Podcasts about Microbiome

Dr. Hoffman continues his interview with Dr. Jacob Teitelbaum, Integrative Medicine physician, researcher, and best-selling author.

In this episode of the Intelligent Medicine podcast, host Dr. Ronald Hoffman discusses the increasing prevalence of depression and anxiety, particularly among young people, with guest Dr. Jacob Teitelbaum, Integrative Medicine physician, researcher, and best-selling author. They explore potential causes, including societal factors, diet, sleep patterns, and the fear-inducing media environment. Dr. Teitelbaum shares insights from his expertise in both conventional and integrative medicine, emphasizing the role of nutritional support, such as magnesium, B vitamins, and curcumin, as well as the importance of psychological strategies, biophysical techniques like shaking off trauma, and natural remedies. They also delve into the potential benefits of alternative therapies like CBD, ketamine, and psychedelics for mental health conditions. Listeners are encouraged to consider a comprehensive approach to managing these pervasive mental health issues.

In this enlightening episode, the hosts delve into the intricate connections between gut health, hormones, and personal well-being. The discussion emphasizes the importance of self-awareness and self-care in achieving a balanced life.

Dr. Hoffman continues his conversation with Jane Jansen, a natural and holistic practitioner from the Tree of Life Wellness Center in Massachusetts, on the importance of the microbiome, particularly the role of probiotics, in maintaining health.

Jane Jansen, a natural and holistic practitioner from the Tree of Life Wellness Center in Massachusetts, focuses on the importance of the microbiome, particularly the role of probiotics, in maintaining health at all life stages. They explore the benefits of specific probiotic strains, the impact of prebiotics and postbiotics, and the use of Dr. Ohhira's Probiotics. Topics also include the relationship between the microbiome and mental health, the implications of commonly used medications like Tylenol on gut health, and practical advice for maintaining a healthy gut during travel and holiday seasons.

Synthetic progestogens hike risk for brain tumors, natural progesterone safe; Healthy microbiome, good genes, clean lifestyle propel world's oldest woman to age 117; Can you take too much selenium? Cannabis extract scores vs. low back pain; Can vitamin K prevent breast calcifications? Are we making progress vs. pancreatic cancer? 

On this episode of Vitality Radio, Jared sits down with Dr. Jason Klop, founder of Novel Biome, to explore one of the most fascinating and misunderstood frontiers in health: fecal microbiota transplant (FMT). Often misnamed “fecal matter transplant,” FMT is a highly purified process that restores microbial diversity in the gut—far beyond what probiotics alone can achieve. Jared and Dr. Klop discuss why FMT is gaining traction in digestive health, neurological conditions, and immune balance, and how it differs from traditional probiotic supplementation. You'll learn about the rigorous donor screening process, oral vs. rectal delivery methods, and why gut microbiome diversity is critical for overall vitality. The potential applications of FMT are broad and promising. This conversation pulls back the curtain on how supporting the gut ecosystem could impact everything from digestion and inflammation to mood and longevity.Additional Information:Novel BiomeNovel Biome - InstagramPodcast – Biome Breakthroughs (Spotify): Listen hereVisit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

How many grams of protein do you need to be healthy? What about fiber? Supplements? It feels like we're changing our diets daily to adhere to constantly shifting recommendations and ...

Matters Microbial #110: Enumerating the Microbiome October 3, 2025 Today Dr. Sean Gibbons, Associate Professor at the Institute for Systems Biology, returns to the #QualityQuorum to tell us about how he and his colleagues are able to listen very carefully to the microbiome to uncover important hints about health. Host: Mark O. Martin Guest: Sean Gibbons Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode Here is the article from Dr. Norm Pace and coworkers on the showerhead microbiome referenced in the podcast. Here is a nonspecialist summary of Dr. Pace's work on the showerhead microbiome and mycobacteria. Here is a link to a prior episode of this podcast with Dr. Ameet Pinto on microbiology of the water supply. Here is Dr. Gibbon's earlier visit to this podcast. An overview of the difference between microbiome and microbiota. An article about the “misnumbering” of the number of microbial to human cells in people.  Here is a nonspecialist summary. An overview of metagenomics. An overview of qPCR. An overview of flow cytometry. Plato's Allegory of the Cave, discussed in this podcast. A cautionary tale about determining a cancer microbiome, as discussed in this podcast. An article by Dr. Gibbons and colleagues described in this podcast about how to estimate microbial biomass directly. An article by Dr. Gibbons and colleagues described in this podcast about how to estimate microbial growth rates in the human gut using metagenomics. An article by Dr. Gibbons and colleagues described in this podcast about how to use metagenomics to determine dietary habits. The website for Dr. Gibbon's research group. The faculty website for Dr. Gibbons at ISB. Courses on microbiome sciences online at ISB. The website for Institute for Systems Biology. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

My most recent coronary calcium score is 1200. What are your recommendations?My husband has been sweating like crazy during our walks. What may be causing this?How serious is RSV for seniors? What about healthy seniors?

The secrets of the world's oldest woman at 117: The microbiome and good genes as determinants of longevityWhat are your thoughts on plasmalogens?Our 24-year-old son has recently been diagnosed with Crohn's disease - help! 

Molecular-medicine expert Dr. Nathan Bryan explains how nitric oxide (NO) protects the endothelium, drives vasodilation, and influences energy, immunity, hormones, and longevity. He links stubborn hypertension and poor exercise tolerance to the microbiome–NO axis and outlines common NO killers—antiseptic mouthwashes and fluoride overuse, chronic PPIs, ultra-processed diets, and inactivity. We cover practical restores (movement, nutrient-dense food, targeted micronutrients, careful PPI weaning, ditching antiseptic rinses) and preview clinical work on NO-releasing lozenges for ischemic heart disease, approaches to improve cerebral blood flow and insulin signaling in cognitive decline, and topical NO for chronic wounds. Bryan also touches on food quality (glyphosate, soil health), hormone synergy with NO, and NO-based skincare that supports perfusion and collagen. Bottom line: rebuild NO, and the body's own repair systems can finally do their job.(Educational only; not personal medical advice.)Guest BioNathan S. Bryan, PhD is a molecular medicine researcher and leading authority on nitric oxide (NO) biochemistry. Over two decades, he has mapped how the body generates and uses NO—and what happens when it doesn't—publishing widely, authoring multiple books, and translating discoveries into products and late-stage drug trials. His work spans cardiovascular health, metabolism, neurocognition, wound healing, and skin biology, with a focus on restoring NO as a foundation for repair. Dr. Bryan speaks globally on NO and leads development of NO-based therapeutics targeting ischemic heart disease, Alzheimer's disease, and non-healing ulcers. GET SOCIAL WITH US!

Reviewing the events of the week and the Bret Weinstein Dark Horse Podcast with Dr. Mark Cannon

Resources:Need resources to help with your bariatric lifestyle? Check out our Bariatric Tools page with meal plans, recipes, GLP-1 guide, etc.AD:Visit Procarenow.com now for all of your vitamin and mineral, calcium and protein needs. Use Code: BSS10 to save $Podcast Guests:Gayle Brazzi Smith MS, RDN, CSOWM, LDNRegistered & Licensed DietitianWeight Loss and Bariatric Surgery InstituteOrlando, FLEmail: gayle.brazzismith@orlandohealth.comWebsite: OrlandoHealth.com/Bariatrics  Bariatric Dietitian Isabel Maples, RDBariatric CoordinatorUVA Health in Haymarket, VirginiaEmail: ggw5ud@uvahealth.org Rate, Review & Follow on Apple Podcasts:"I love Dr. Susan and Bariatric Surgery Success." If this sounds like you, would you please rate and review my podcast? I love hearing from you, and it's actually super easy for you to leave a podcast rating. Wherever you listen to the Bariatric Surgery Success podcast, go to the review section and usually click a quick star rating. If you feel like taking it one small step further, please write a review if there's a place for one. Thank youSummaryIn this episode, Dr. Susan Mitchell and expert dietitians Isabel Maples and Gayle Smith discuss the importance of gut health and how everyday foods can support a healthy microbiome. They explore the role of various foods, particularly those high in fiber and probiotics, in promoting gut health and overall well-being. The conversation emphasizes practical tips for incorporating gut-friendly foods into daily meals and the significance of diversity in diet for optimal gut function.TakeawaysYou don't need expensive supplements to support your microbiome.The gut microbiome consists of trillions of bacteria, viruses, and fungi.Good gut health is crucial for digestion, immune function, and mood.Different foods can encourage the growth of beneficial gut bacteria.Fiber acts as food for gut bacteria, promoting their health.Probiotics are beneficial bacteria that support digestive health.Prebiotics are the food that healthy bacteria feed on.Incorporating a variety of foods can enhance gut microbiome diversity.Aim for 30 different plant foods each week for optimal gut health.Simple changes in diet can lead to significant improvements in gut health.Chapters00:00 Introduction to Gut Health and Nutrition02:58 Understanding the Gut Microbiome05:57 The Role of Food in Gut Health09:04 Key Foods for a Healthy Gut12:02 The Importance of Fiber and Probiotics14:50 Practical Tips for Incorporating Gut-Healthy Foods18:10 Conclusion and Key Takeaways

In this episode of The Brand Called You, Ashutosh Garg speaks with Dr. Debojyoti Dhar, co-founder of Leucine Rich Bio Pvt Ltd. From childhood curiosity to pioneering microbiome science in South Asia, Dr. Dhar shares his journey of balancing research, entrepreneurship, and integrity while shaping the future of health through gut science.00:35- About Dr Debojyoti DharDr. Debojyoti Dhar is the co-founder and director of Leucine Rich Bio Pvt Ltd. He has been nominated as a member of the expert committee constituted by the government of India on functional foods.He is the co-author of a book titled I, Microbiome: A Secret to a Healthy and Balanced Human Body.

The cause of autism revealed—is it Tylenol? Is there an ideal probiotic for Crohn's Disease? Treating constipation by modifying the microbiome with botanicals; ACTION ALERT: If Congress has its way, 95% of natural hemp products with CBD/THC may be banned by year's end! The popular diet that reverses psoriasis; A daily habit that could save you from chronic back pain.

Imagine living life without a brain... you'd be in pretty rough shape. But most of us are ignoring the health of our second brain.  Your gut is the second brain and the gut-brain connection they share is so isunderstood. But once you undertstand it, it's like a cheat code for the rest of your life.   TOPICS DISCUSSED IN THIS EPISODE: What the gut-brain connection actually is How your gut and brain communicate Why this connection must ne healthy for a healthy life How leaky gut causes leaky brain What your gut produces (90% of your serotonin, etc...) How your gut controls your immune system The power of your gut microbiome and how it shapes your moods, thoughts and overall health Dr. Nandi's 5 pillars for total wellness   More from Dr. Partha Nandi Website: askdrnandi.com Facebook: @AskDrNandi Instagram: @AskDrNandi Twitter / X: @AskDrNandi TikTok: @AskDrNandi   Leave us a Review: https://www.reversablepod.com/review   Need help with your gut? Visit my website gutsolution.ca to join a program: Get help now   Contact us: reversablepod.com/tips    FIND ME ON SOCIAL MEDIA: Instagram  Facebook  YouTube         

In this Huberman Lab Essentials episode, I explain how the immune system defends against infection and describe the relationship between the immune and nervous systems. I discuss the immune system's three primary layers of defense, emphasizing how each contributes to protection from infection. I share practical tools to enhance immune function and accelerate recovery from sickness, including specific breathing patterns, sleep positioning and targeted supplementation. I also explore the powerful mind-body connection, showing how mindset and nervous system activation can directly influence the body's ability to heal. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman LMNT: https://drinklmnt.com/huberman Timestamps (0:00) Immune System & Nervous System (0:33) Immune System 101, Innate & Adaptive Immune Systems (8:03) Mucus & Microbiome, Tools: Nasal Breathing; Avoid Eyes; Ingest Fermented Foods (10:57) Sponsor: AG1 (12:04) Sickness Behavior & Vagus Nerve, Fever, Photophobia, Rest (16:43) Humoral Factors, Inflammatory Cytokines (18:14) Sleep & Enhancing Immune System, Glymphatic System, Tool: Elevate Feet (21:12) Sponsor: LMNT (22:44) Stress & Inflammation, Tool: Early Symptoms & Cyclic Hyperventilation (31:09) Positive Mindset & Immune Function, Dopamine (34:03) Electroacupuncture, Fascia, Catecholamines & Inflammation (36:22) Accelerating Recovery, Medication, Tool: Spirulina & Rhinitis (38:34) Recap & Key Takeaways Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

Gut health isn't just about digestion - it shapes your metabolism, hormones, and even your cravings. In this episode, Dr. Will Cole welcomes back Colleen Cutcliffe, PhD, co-founder of Pendulum, to break down the cutting-edge science of the microbiome. From antibiotics and diet to fasting, fiber, and fermented foods, Colleen shares how keystone strains like Akkermansia impact GLP-1, insulin, and metabolic health. Learn why your gut resilience is the key to everything from energy to cravings, and how to rebuild it naturally. For all links mentioned in this episode, visit www.drwillcole.com/podcast.Go to pendulumlife.com and use code WILLCOLE to get 20% off all Pendulum membership first orders. Discount applied at checkout.Please note that this episode may contain paid endorsements and advertisements for products and services. Individuals on the show may have a direct or indirect financial interest in products or services referred to in this episode.Sponsors:Get better sleep, hair and skin with Blissy and use WILLCOLE to get an additional 30% off at blissy.com/WILLCOLE.MANUKORA.com/WILLCOLE to save 31% plus $25 worth of free gifts.Save 30% off your first subscription order & receive a free six pack of Ketone-IQ with KETONE.com/WILLCOLE.Get 20% off, or if you choose the already discounted subscription, you get almost a third off the price! Go now to get this amazing discount: PUORI.com/WILLCOLE.Start your love story on Bumble. Pique is hooking you up: 20% off for life—yes, FOR LIFE—plus a FREE rechargeable frother and glass beaker when you grab their Pu'er Bundle. Go to Piquelife.com/willcole to grab yours now.Produced by Dear Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

IRON: It's a part 3 of sorts, as we've covered Iron twice on the show previously but given the questions that continue to come in: This is the show to round it all out thoroughly. We unpack: Iron - when it's a friend, foe and how to get into a ‘healthier relationship with it'. Why your body might think it needs to protect you from iron Understanding inflammation to understand your iron challenges betterIron as it travels through the digestive tract - a deep dive into all that has to be ‘just right' for iron levels and absorption to be healthy. Microbiome factors when it comes to healthy iron absorptionWhy we need a lot more research on iron and women's heatlhWhy iron supplementation shouldn't be your first “go to fix” when it comes to iron deficiencyWhat you can do to further investigate your iron beyond iron studies blood tests. How to move forward in your diet and health focuses to maintain healthy iron levels. And we explore all of this with Rebecca Edwards, Director of Education at Activated Probiotics. With over 2 decades of naturopathic clinical experience, Rebecca educates clinicians globally in all areas of naturopathy, with a special passion for iron absorption, given the many factors that play into it - so luck to have Rebecca to help us dive further into the fascinating topic of IRON. Note: This episode is in no way funded by or influenced by the company Rebecca works for. You can trust that I will never allow for a paid guest spot. Rebecca is an exceptional educator, and our community had more questions on Iron and she was the perfect person. On our podcast you can be sure that ads are ads, and show guests are guests because of their subject matter, not because of what they sell. Enjoy the show and share it with someone who needs support with their iron, Alexx xThank you to this month's show partners for joining us to help you make your low tox swaps! @forestsuperfoods is back with a very generous offer for all new subscribers: Subscribe to a product you know you take regularly from their organic, wholefood, filler-free supplement range and every month receive a mystery luxe-sized product or supplement - enough for a 7-14 day supply to really test it out, product depending. Link in Bio and change products in your subscription every month - super flexi! https://www.forestsuperfoods.com.au/pages/low-tox-life @ausclimate is our major partner giving you 10% off their range for the whole of 2025, with brilliant Winix Air Purifiers, the best Dehumidifiers I've ever used and their new energy-efficient heating, air-circulating and cooling range. code LOWTOXLIFE (also works over and above their sales - pro tip!) https://bit.ly/ShopAusclimateBe sure to join me on Instagram @lowtoxlife and tag me with your shares and AHAs if something resonated! I love to see your thoughts, genuinely! Hosted on Acast. See acast.com/privacy for more information.

Your gut holds the key to your overall health—and now, you can finally decode it.

NBC News Medical Contributor Dr. Natalie Azar discusses gut health and creating a healthy microbiome. Plus, Selma Blair opens up about her personal journey navigating multiple sclerosis. Also, Jesse Williams talks his new action-comedy 'Hotel Costiera.' And, Orthopedic Physical Therapist, Karena Wu shares some footwear upgrades to ease pain and discomfort. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

September is Cholesterol Education Month. In this episode of Intelligent Medicine, Jim LaValle, a clinical pharmacist and certified clinical nutritionist, details cholesterol's importance and its implications for cardiovascular health. He delves into the nuances of cholesterol types, the historical shifts in perceptions of cholesterol, and how dietary and lifestyle factors influence cholesterol levels and cardiovascular risk. Jim provides expert insights into the roles of LDL and HDL cholesterol, the significance of cholesterol particle size, the impact of carbohydrates on cholesterol, and the benefits of aged garlic extract and other supplements. The conversation emphasizes the importance of comprehensive lipid testing, understanding individual risk factors, and integrating both lifestyle modifications and, when necessary, medications into cardiovascular preventive strategies. The episode concludes with a discussion on the role of health policies and the future of integrative health approaches.

Dr. Hoffman continues his conversation with Jim LaValle, a clinical pharmacist and certified clinical nutritionist, detailing cholesterol's importance and its implications for cardiovascular health. 

In this episode of the Pain and Performance Podcast, I sit down with Anu to explore how gut health impacts everything from energy and motivation to inflammation, mental health, and recovery.We dive into how your microbiome diversity shapes performance, why intentional eating matters more than most people realize, and how stress, exercise, sleep, and even mindset play key roles in gut health. Anu also shares her MBHR framework: Microbiome, Brain, Hormones, and Reframing mindset, and real patient stories that highlight how small, consistent changes can transform health.If you've ever struggled with fatigue, brain fog, cravings, or stubborn inflammation, this conversation will help you understand why your gut may be the missing link, and what you can do to fix it.Key Takeaways-- Gut diversity fuels motivation, dopamine, and higher performance.-- Intentional eating is one of the fastest ways to change gut health.-- Stress disrupts digestion, raises cortisol, and drives belly fat.-- Exercise reduces inflammation, boosts digestion, and supports microbial diversity.-- Gut imbalances influence cravings, brain fog, and mood.-- Targeted probiotics and prebiotics work — but not all strains help.-- Sleep and gut health are directly connected to cravings and insulin resistance.-- Food is either poison or medicine — cut triggers like sugar, gluten, and processed oils.-- The gut is the lead domino: fix it and you improve inflammation, weight, pain, and clarity.Gut health isn't just about digestion; it's about energy, clarity, recovery, and long-term vitality. Fix your gut, and you set the foundation for everything else.Links:DERRICKTikTok:https://www.tiktok.com/@drderrickInstagram:https://www.instagram.com/derrickbhines/Youtube:https://www.youtube.com/@DrDerrickANU:Buy her book here: https://www.amazon.com/Flourish-Within-Feed-Lifelong-Health/dp/1954493797/ref=sr_1_1?crid=9Z49DJGUXZTJ&dib=eyJ2IjoiMSJ9.kU7039-KFUhIHFg1Bnfc_syYtZkl3p_lrN1XOsYWxc1tN8OTrvwLud49ZtEIBefDWuc27ZRGlSurMIVr8TjbHcI_JzqgQiZYn4fj_7kuYG0Ng9cPow0tX3YvmjXpdC1ABJWiFaJAerr_dFxGgA7SggmStPW4VexQVDXw0i5GV6yn8paIzaFuSei3WzsI1zTTvmZCe9e9k7g5x9HQpBAQC7S1TPnQG0xyHgIecuegnws.uEqsN5zv2kS04bkIegNOaVNJvhrXBaroiWequAPsSAU&dib_tag=se&keywords=flourish+from+within&qid=1758677205&sprefix=flourish+f%2Caps%2C597&sr=8-1 Instagram: https://www.instagram.com/9armsofwellness/Youtube:https://www.youtube.com/@BadMedicinePodcastWebsite:https://www.9armsofwellness.com/

#302 Welcome back to Love and Guts! In this episode, Dan Sipple returns for a deep dive into the intertwined worlds of gut health and hormonal balance. Dan, a naturopath, nutritionist, and herbalist, brings over his expertise to discuss the impact of hormonal changes during perimenopause and andropause on gut motility, permeability, and microbial diversity. This conversation highlights the importance of cortisol, microbial composition, neurotransmitter modulation, and lifestyle interventions like diet and strength training. Dan also touches on innovative therapies such as bio-identical hormones, peptides, and the essential role of bile acids. Don't miss this extensive and insightful discussion that's packed with valuable tips for managing midlife hormonal shifts and gut health.   Connect: Guest: https://thefunctionalnaturopath.com/about Host: lynda_griparic_naturopath  

Bret Weinstein speaks with Dr. Mark Cannon on the subject of the microbiome.Dr. Mark L Cannon is a Professor Emeritus from Ann & Robert H. Lurie Children's Hospital of Chicago and Northwestern University.*****Sponsors:Everyday Dose: Coffee plus collagen, mushrooms & nootropics – delicious! Get 45% off your first subscription order and also receive free gifts at http://everydaydose.com/darkhorse.Jolie: Beautiful shower heads that filter out the garbage without reducing water pressure. Go to http://jolieskinco.com/DarkHorse to get free shipping; free returns within 60 days.Prima is offering 20% off their fantastic bars. Go to http://EatPrima.com/DarkHorse to get 20% off. Try Prima ancestral protein bars today!*****Join DarkHorse on Locals! Get access to our Discord server, exclusive live streams, live chats for all streams, and early access to many podcasts: https://darkhorse.locals.comCheck out the DHP store! Epic tabby, digital book burning, saddle up the dire wolves, and more: https://www.darkhorsestore.orgTheme Music: Thank you to Martin Molin of Wintergatan for providing us the rights to use their excellent music.Support the show

Send us a textHow maternal obesity epigenetically reprograms liver metabolism in offspring, predisposing them to metabolic disease.Episode Summary: Dr. Elvira Mass talks about macrophages, specialized immune cells that vary by tissue and play crucial roles beyond fighting infections, such as supporting organ function; Kupffer cells (liver macrophages) and how maternal obesity during pregnancy reprograms these cells in offspring, leading to fatty liver disease, fibrosis, and even cancer later in life, based on mouse studies showing epigenetic and metabolic shifts like increased glycolysis, with insights into developmental windows, nutritional mismatches, and broader implications for human health.About the guest: Elvira Mass, PhD, is a Professor of Developmental Immunology at the University of Bonn in Germany, where her lab focuses on the development and function of macrophages in various tissues.Discussion Points:Macrophages are diverse, tissue-specific cells that develop from embryonic precursors, performing unique tasks like providing growth factors in organs.Kupffer cells in the liver monitor blood from the gut and are exposed to maternal nutrients during fetal development.Maternal obesity (induced in mice via high-fat diets) programs offspring Kupffer cells epigenetically, leading to fatty liver in newborns and progression to diseases like cancer, even on normal diets.A "nutritional mismatch" between in utero high-fat exposure and postnatal normal diets worsens liver issues, as cells are "prepared" for excess high-fat intake but face scarcity.Key mechanism: Reprogrammed Kupffer cells overproduce apolipoproteins, driving excess lipid uptake in liver cells (hepatocytes), linked to transcription factor HIF-1α and a shift to inefficient glycolysis.Offspring from obese mothers show sex differences (males affected earlier) and persistent changes.Human parallels: Rising childhood fatty liver (once rare and tied to alcoholism) correlates with maternal obesity; studies like Dutch Hunger Winter show early gestational disruptions cause lifelong issues.Broader factors: Microbiome changes, specific fatty acids, and environmental toxins like microplastics may also reprogram macrophages; diets in studies vary beyond fat content, affecting results.Advice: Maintain consistent healthy habits pre- and during pregnancy; avoid sudden diet shifts, as developmental windows are critical for long-lived cells like Kupffer cells.Reference Paper:Study: Kupffer cell programming bySupport the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. For all the ways you can support my efforts

In this encore episode, we detail hypochlorhydria while reviewing gastric lining anatomy, highlighting hydrochloric acid (HCl) secretion and its role in digestion, micronutrient absorption, and microbial defense. We discuss potential downstream effects of hypochlorhydria, including impaired digestive signaling, bacterial overgrowth in the small intestine (SIBO), and more. Lastly, we detail upstream microbial control, focusing on possible influences of the oral microbiome and oral dysbiosis.Topics: 1. Introduction- Highlighting the stomach and hypochlorhydria / low stomach acid, as well as microbial balance, dysbiosis, and overgrowth.- Discussion of intestinal microbiome and oral microbiome. 2. Gastric Anatomy and Mucosal Layers- The stomach: cardia, fundus, body, pylorus.- The gastric mucosa: epithelial lining, lamina propria, muscularis mucosae.- The epithelial layer: mucous cells, parietal cells, chief cells, enteroendocrine cells.- Beneath the mucosa: submucosa and muscular layers that contribute to gastric motility, mechanical digestion, and more. 3. Mucous Cells - The surface epithelium and gastric pits.- Secretion of thick, viscous mucus.- Protecting the epithelium.- The mucus traps bicarbonate ions: neutral microenvironment that protects against acid-induced damage. 4. Parietal Cells and Gastric Acid Secretion- Secretion of hydrochloric acid (HCl): denatures dietary proteins, sterilizes ingested food.- Parietal cells produce intrinsic factor: binds vitamin B12 to facilitate absorption in the ileum. 5. Chief Cells and Pepsinogen- Secretion of pepsinogen: activated by low pH into the proteolytic enzyme pepsin.- Pepsin and protein digestion.- Release of gastric lipase. 6. Hydrochloric Acid: Digestive and Protective Roles- Immune defense.- Pepsinogen activation.- Adequate gastric acidity essential for properly acidified chyme.- Priming release of bile and pancreatic enzymes. 7. The Small Intestine, Stomach, and Microbial Regulation- The pyloric sphincter.- The stomach supports minimal microbial diversity.- Acidic barrier aids in limiting the entry of opportunistic microbes into the small intestine. 8. Hypochlorhydria, Low Stomach Acid- Hypochlorhydria can compromise one of the body's defense mechanisms.- Colonization of the small intestine.- Insufficient pepsinogen activation and possible protein digestion impairment.- Suboptimal chyme formation and downstream digestive capacity.- Possible symptoms of hypochlorhydria.- Possible impaired absorption of micronutrients including vitamin B12, iron, calcium, magnesium.- H. pylori infection, autoimmunity, aging. 9. The Oral Microbiome, Intestinal Microbiome, and Dysbiosis- Oral and environmental microbes.- Altered gastric pH, bile, digestive enzymes, and more.- The oral cavity as the gateway to the GI tract.- Oral microbial species.- Oral hygiene and oral microbiome health. 10. Conclusion- Root-cause approach.Thank you to our episode sponsor: 1. ⁠⁠⁠⁠⁠⁠⁠⁠OmneDiem®'s⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠Histamine Digest®⁠⁠⁠⁠⁠⁠⁠⁠ and ⁠⁠⁠⁠⁠⁠⁠⁠Histamine Digest® PureMAX⁠⁠⁠⁠⁠⁠⁠⁠ : Use code STXAL9VI for 15% off.2. ⁠⁠⁠⁠⁠⁠⁠⁠Histamine Digest® Histamine Complete⁠⁠⁠⁠⁠⁠⁠⁠ with DAO, Vitamin C, Quercetin, Bromelain, and Stinging Nettle Root Extract: Use code STXAL9VI for 15% off.Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

View This Week's Show NotesStart Your 7-Day Trial to Mobility CoachJoin Our Free Weekly Newsletter: The AmbushFeeling tired after meals, battling brain fog, or wondering why your gut health feels off? Dr. Amy Shah — a double board-certified physician, nutrition expert, and bestselling author — reveals how your microbiome holds the key to energy, mood, and long-term wellness. In this episode of The Ready State Podcast, she breaks down the hidden impact of ultra-processed foods, the surprising role of microbes and dirt in childhood, and why circadian rhythms matter as much as diet. From understanding the “energy trifecta” to mastering her 30/30/3 rule, Dr. Shah shares simple, science-backed steps that make gut health practical and powerful. Tune in for clear, actionable insights to help you eat smarter, sleep better, and feel truly energized every day.What You'll Learn in This EpisodeWhy ultra-processed foods confuse your brain and immune systemHow dirt, animals, and early exposure shape a child's microbiomeThe truth about fermented foods — and which ones actually workWhat Dr. Shah calls the “energy trifecta” for boosting mood and focusWhy most Americans aren't getting nearly enough fiberHow circadian rhythms (and when you eat) impact gut healthA simple 30/30/3 rule to reframe your daily nutritionKey Highlights: 00:00 - Preview01:06 - Intro02:00 - Dr. Amy Shah's Journey08:58 - Ultra-Processed Foods11:48 - Gut and Immune System Connection18:15 - Benefits of Fermented Foods21:21 - Energy Trifecta Explained25:20 - Gut-Brain Connection Insights31:51 - Momentous: Importance of Vitamin D34:41 - LMNT: Benefits of Salty Morning38:45 - Importance of Fiber in Diet42:33 - Hunger, Appetite, and Cravings Explained46:53 - Role of Circadian Rhythms53:13 - Understanding Appetite56:24 - Skin Health and Nutrition1:00:50 - Food Allergies Overview1:06:08 - Current Trends: Megan's Insights1:08:23 - Benefits of Circadian Fasting1:09:44 - Where to Find Dr. Shah1:10:16 - Dr. Shah's BooksSponsorsThis episode of The Ready State Podcast is brought to you by Momentous, and LMNT.

Bad bacteria in the mouth trigger 54 systemic inflammatory diseases, from heart disease to Alzheimer's. The inflammation doesn't stay local. It travels through your bloodstream, attacking every organ in your body. In this episode, I sit down with Dr. Jonathan Levine to explore the science of oral-systemic health. We discuss his revolutionary mouth mapping system, the truth about root canals and mercury fillings, and why your primary physician might be unaware of critical health clues hiding in your mouth. Dr. Levine reveals simple daily routines that take just three minutes but can transform your oral microbiome, plus surprising connections between mouth breathing, sleep apnea, and chronic disease that could be the missing piece in your health puzzle.   "The mouth is connected to the rest of the body. What happens in the mouth goes to the body." ~ Dr. Jonathan Levine   In This Episode: - Oral microbiome's role in longevity: beware of mouthwash - Mercury fillings: the neurotoxin in your mouth - Aluminum in composite fillings - Inside Smile House and the Mouth Mapping™ system - Sleep apnea, mouth breathing, and jaw development - Mouth taping benefits and home sleep test options - Cone beam scans and what they reveal - The root canal debate: when to treat, when to extract - Wisdom teeth, cavitations, and PRP for healing - Building an effective daily oral care routine - Insight on fluoride, hydroxyapatite, and more tips for oral care   Products & Resources Mentioned: Puori PW1 Whey Protein & Creatine+: Go to https://puori.com/wendy and use code WENDY to get 20% off your entire order, even on discounted subscriptions. Tru Energy Lip Peptide Treatment: Visit https://trytruenergy.com/wendy3 now to claim your special Buy One, Get One Free offer for a limited time. Qualia Senolytic: Get 15% off with code WENDY at https://qualialife.com/wendy  Heavy Metals Quiz: Start now at https://heavymetalsquiz.com    About Dr. Jonathan Levine: Dr. Jonathan Levine is a prosthodontist, innovator, and one of America's most sought-after voices in oral health and dental longevity. With over 35 years of clinical experience, 29 patents, and a pioneering role in aesthetic dentistry, he is the founder of Smile House in New York City,  a destination for integrative and functional dentistry. Through his GLO Good Foundation, he delivers vital dental care and education to underserved communities worldwide. Learn more at smilehouse.co.    Disclaimer The Myers Detox Podcast was created and hosted by Dr. Wendy Myers. This podcast is for information purposes only. Statements and views expressed on this podcast are not medical advice. This podcast, including Wendy Myers and the producers, disclaims responsibility for any possible adverse effects from using the information contained herein. The opinions of guests are their own, and this podcast does not endorse or accept responsibility for statements made by guests. This podcast does not make any representations or warranties about guests' qualifications or credibility. Individuals on this podcast may have a direct or indirect financial interest in products or services referred to herein. If you think you have a medical problem, consult a licensed physician.

Episode Notes Welcome to another special edition of NHA Today, the official podcast of the National Health Association. As part of our guest host series, this episode is led by Chuck Carroll, host of The Exam Room Podcast from the Physicians Committee for Responsible Medicine (PCRM). Chuck is joined by Dr. Will Bulsiewicz (“Dr. B”), The Gut Health MD, for a wide-ranging conversation on gut health, healing, and lifestyle medicine. Together they explore: Why heartburn and GERD are really gut motility issues The role of diet, fiber, and the microbiome in supporting long-term health The risks of long-term reliance on reflux medications How stress, sleep, and exercise influence digestion through the gut-brain axis The importance of community, including Dr. B's Gut Health Collective Insights from his upcoming book Plant Powered Plus This episode delivers practical strategies and empowering science for anyone looking to improve their gut health and overall well-being.   Links & Resources

Interview with Jiyoung Ahn, PhD, author of Oral Bacterial and Fungal Microbiome and Subsequent Risk for Pancreatic Cancer. Hosted by Vivek Subbiah, MD. Related Content: Oral Bacterial and Fungal Microbiome and Subsequent Risk for Pancreatic Cancer

We're fascinated by the microbiome — and for good reason. But how do we protect this invisible ecosystem that plays such a vital role in our health?From engineering live, programmable therapeutics that disarm dangerous gut pathogens to creating a global “doomsday vault” to safeguard the diversity of human gut microbes, we dive deep into the cutting-edge science shaping the future of microbiome research.Show notes1. Ronda, C., Perdue, T., Schwanz, L. et al. Precise virulence inactivation using a CRISPR-associated transposase for combating Enterobacteriaceae gut pathogens. Nat. Biomed. Eng (2025). https://doi.org/10.1038/s41551-025-01453-12. 2. Dominguez-Bello, M.G., Steiger, D., Fankhauser, M. et al. The microbiota vault initiative: safeguarding Earth's microbial heritage for future generations. Nat Commun 16, 5373 (2025). https://doi.org/10.1038/s41467-025-61008-5

Alexis Schultz, a research scientist for Standard Process, focuses on agronomy research, plant breeding, and crop development on the Standard Process certified organic farm. Bridging the connection between healthy soils, resilient crops, and superior nutrition is at the heart of Alexis' work. With a deep understanding that our health begins with the soil and the food we grow from it, she's dedicated to research that strengthens the link between agriculture and well-being. Listen in as Alexis and Dr. Sarah Clarke engage in an educational and inspirational conversation about healthy soil – how to build it and why it's important for good health.  2:06 What constitutes healthy soil and how healthy soil affects our health 5:10 How the microbiome of each plant compare to the human microbiome 8:32 Keeping soil healthy with regenerative and organic farming practices 11:16 How cover cropping improves the diversity of the root system 14:16 Using compost to enrich soil 17:10 Organic farming practices used to maintain organic certification and prevalence of organic farming in the US 19:45 Plant breeding defined and how it differs from GMOs 22:53 Ancient Oats – history of cultivation and how the nutrient content has changed 25:40 Benefits of seed selection and variety trials 27:38 Growing mountain spinach – does the bright red color of this plant contain more phytonutrients than less vibrant varieties? 29:40 Emphasis on research at the Standard Process Farm 30:56 Alexis as a guest speaker at the Whole Systems Nutrition Virtual Symposium on October 24th

In this episode of the Smarter Not Harder Podcast, Dr. Vivek Lal joins Dr. Scott Sherr for a groundbreaking and eye-opening conversation about the gut-lung axis — the overlooked connection between your microbiome and your ability to breathe, perform, and recover. From inhaled probiotics to AI‑driven lung therapy, this episode bridges clinical science and next‑gen wellness in a way you've never heard before. Join us as we delve into: How gut bacteria directly influence lung inflammation, asthma, and COPD Why your lungs aren't sterile — and what lives in them might save your life The rise of inhaled postbiotics and what “air as medicine” really means Cutting-edge lung science: AI, organoids, omics, and future therapies This episode is for you if: You've never heard of the gut-lung axis but want to breathe, sleep, and recover better You or someone you love has asthma, COPD, or unexplained breathing issues You're fascinated by how microbiomes affect health far beyond the gut You want smarter, not harder, ways to optimize lung health and longevity You can also find this episode on…  YouTube: https://youtu.be/PZZw8ulAHiM  Find more from Dr. C. Vivek Lal, MD, FAAP: Resbiotic Nutrition: https://resbiotic.com/ LinkedIn: https://linkedin.com/in/c-vivek-lal-md-faap-20183913 Instagram: https://instagram.com/dr.viveklal/ Find more from Smarter Not Harder: Website: https://troscriptions.com/pages/podcast Instagram: https://instagram.com/troscriptions/ HOMeHOPe Symposium: https://homehope.org/homehope-symposium Get 10% Off your purchase of the Gut Lung Axis Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Troscriptions order with code POD10 at https://www.troscriptions.com

Martha Carlin, CEO and founder of the Bio Collective, details the significant influence of the microbiome on overall health. Martha discusses her unconventional path from accounting to microbiome research, sparked by her husband's Parkinson's diagnosis. Together, they explore the complex connections between gut health and diseases like Parkinson's, autism, and even Alzheimer's. Martha sheds light on groundbreaking research funded by NIH grants, the potential of machine learning and AI in understanding microbiome patterns, and the future prospects of personalized probiotics. Practical advice on maintaining a healthy microbiome, the impact of diet and exercise, and the intriguing intersections between gut health, neurochemistry, and systemic diseases are highlighted. The discussion also covers challenges in integrating microbiome research into clinical practice and potential future therapies.

Dr. Hoffman continues his conversation with Martha Carlin, CEO and founder of the Bio Collective.

Could the water you drink impact your gut health? In this episode, Dr. Greg Nigh discusses deuterium-depleted water, sulfur metabolism and hydrogen sulfide SIBO and their relationship with digestion, energy and overall health. You'll also hear practical insights on ketogenic and carnivore diets, plus emerging therapies like peptides and infrared light. Lindsey Parsons, your host, helps clients solve gut issues and reverse autoimmune disease naturally. Take her quiz to see which stool or functional medicine test will help you find out what's wrong. She's a Certified Health Coach at High Desert Health in Tucson, Arizona. She coaches clients locally and nationwide. You can also follow Lindsey on Facebook, Tiktok, X, Instagram or Pinterest or reach her via email at lindsey@highdeserthealthcoaching.com to set up your free 30-minute Gut Healing Breakthrough Session. Show Notes

Ancient Teeth Reveal Insights into Evolution of Oral MicrobiomesBy Today's RDH ResearchOriginal article published on Today's RDH: https://www.todaysrdh.com/ancient-teeth-reveal-insights-into-evolution-of-oral-microbiomes/Need CE? Start earning CE credits today at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://rdh.tv/ce⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Get daily dental hygiene articles at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.todaysrdh.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Follow Today's RDH on Facebook: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.facebook.com/TodaysRDH/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow Kara RDH on Facebook: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.facebook.com/DentalHygieneKaraRDH/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow Kara RDH on Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/kara_rdh/

Laura & Clayton chat with Christina O'Connor, Registered Dietitian at Pendulum, about why gut health is the foundation of overall wellness, and why everyone's buzzing about Akkermansia. Christina breaks down how this powerful next-generation probiotic supports your gut lining, balances blood sugar, and helps keep inflammation in check. Learn what makes Akkermansia unique, how to nourish your microbiome through diet and lifestyle, and why a healthy gut can be the key to feeling your best from the inside out. Resources & Links: Pendulum: Code FUNC for 20% off all subscription orders at Pendulum. JASPR Air Purifiers: Code FUNC for a discount at JASPR.  Adapt Naturals: Discount at https://www.adaptnaturals.com/FUNC. Naturepedic: Code FUNC15 for a discount at 

Alliance for Natural Health sues FDA to allow truthful, science-based health claims for 118 vitamins, minerals and nutraceuticals in 1st Amendment test; What to do for H. pylori—or should it even be treated? Whole body MRI for cancer screening—is it worth undertaking? A remarkable new functional food supplement and beverage, harnessing the unique benefits of the muscadine grape. 

Dr. Derya Unutmaz joins Dr. Buck Joffrey to discuss the critical role of T cells in the immune system, their changes with aging, and the implications for chronic diseases. He emphasizes the importance of thymus regeneration and the microbiome's influence on health. The discussion also covers advancements in engineering immune cells for cancer treatment and the potential of AI in revolutionizing aging research and drug discovery. Unutmaz expresses optimism about the future of aging research, highlighting the need for a shift in how aging is perceived in the medical community. Learn more about Dr. Derya Unutmaz: https://www.jax.org/research-and-faculty/faculty/derya-unutmaz - Download Dr. Buck Joffrey's FREE ebook, Living Longer for Busy People: https://ru01tne2.pages.infusionsoft.net/?affiliate=0 Book a FREE longevity coaching consultation with Dr. Buck Joffrey: https://coaching.longevityroadmap.com/

Want to biohack your biology with nature's most powerful anti-aging compounds? In this episode, you'll discover how medicinal mushrooms fuel neurogenesis, protect mitochondria, supercharge immunity, and even help save the planet's pollinators. From sharper focus and deeper REM sleep to protecting DNA from oxidative stress, fungi are the ultimate biohacking tools for performance, resilience, and longevity. Watch episodes on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR (Re-run) Host Dave Asprey sits down with legendary mycologist and author Paul Stamets and mushroom entrepreneur Julian Mitchell. Together, they uncover the science of fungi as medicine — how mushrooms repair nerves, fight viruses, act as prebiotics for your microbiome, and provide the ultimate anti-aging biohacks. You'll also hear how fungi hold the key to saving pollinators, regenerating soil, and extending human longevity. You'll Learn: • Which anti-aging compounds in mushrooms protect your mitochondria and DNA • How lion's mane stimulates nerve growth factor and improves memory, focus, and REM sleep • Why oyster mushrooms may help fight flu viruses and reduce chronic inflammation • How mushroom tinctures unlock more bioactive compounds than powders or capsules • The surprising role fungi play in saving bees and restoring environmental balance Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: anti-aging mushrooms, Paul Stamets fungi, lion's mane memory, mushroom tincture benefits, ergothionine mitochondrial protection, oyster mushroom flu prevention, reishi immune system, cordyceps endurance, turkey tail microbiome, medicinal mushroom research, fungi save the bees, chaga antioxidants, mushroom longevity biohack, mycelium networks, functional mushrooms anti-inflammatory, mushroom brain health, neurogenesis fungi, adaptogenic mushrooms, mushroom cooking bioavailability • Lifecykel Mushroom Products - use code ‘DAVE20' for 20% off: https://www.lifecykel.com/?rfsn=4497217.61b030&utm_source=refersion&utm_medium=affiliate&am… • Paul Stamets' Website: https://hostdefense.com/ Thank you to our sponsors! • ECHO Water | Go to http://echowater.com/dave and use code DAVE10 for 10% off your ECHO Flask. Resources: • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: • 0:00 — Trailer • 0:47 — Intro • 6:15 — Mushrooms vs. Algae • 10:21 — Mushroom Safety & Microbiome • 12:24 — Mushrooms as Medicine • 14:43 — Psychedelics & Microdosing • 16:26 — Kakadu Plum & Prebiotics • 18:07 — Oyster Mushrooms & Cooking • 21:35 — Mushrooms & Bees • 25:59 — Lion's Mane & Chaga See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

TWiM explores the varied and distinct microbiome of trees, and an array of biopesticidal metabolites against mosquito larvae isolated from a Mediterranean island. Become a patron of TWiM. Links for this episode: Microbiome of trees (Nature) Biopesticides from a Mediterranean island (Appl Environ Micro) Music used on TWiM is composed and performed by Ronald Jenkees and used with permission. Send your microbiology questions and comments to twim@microbe.tv

In this episode, Dr. Jeffrey Gladden and Dr. Emaline Brown discuss the critical role of gut health in longevity and overall well-being. They explore the Gut Zoomer test, its significance in identifying gut microbiome health, and how dietary choices impact gut health. The conversation delves into the importance of fiber, the implications of leaky gut, and the effects of alcohol on gut health. They also highlight the connection between gut health and metabolic processes, emphasizing the need for a balanced diet rich in diverse plant-based foods.   For Audience ·       Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/ !    Takeaways ·       Gut health is essential for overall health and longevity. ·       Stool testing can provide insights for everyone, not just those with symptoms. ·       An altered gut microbiome is a significant marker of aging. ·       Dietary fiber, especially from plants, is crucial for maintaining gut health. ·       Hydrochloric acid plays a vital role in digestion and gut health. ·       Alcohol can negatively affect gut health and contribute to leaky gut. ·       Food serves as information for our body, influencing our health. ·       Maintaining a diverse diet can optimize nutrient status and gut health. ·       Leaky gut can lead to systemic inflammation and various health issues. ·       The gut microbiome is integral to metabolic health and hormone balance.   Chapters 00:00 Introduction to Gut Health and Testing 03:34 Understanding the Gut Zoomer Test 07:45 The Importance of Gut Microbiome for Longevity 11:49 The Role of Diet in Gut Health 15:30 Detecting Pathogens in the Gut 18:07 New Features of the Gut Zoomer Test 24:50 Leaky Gut and Its Implications 29:37 Systemic Impact of Gut Health 32:00 The Role of Gut Microbiome in Metabolic Health 34:34 Hormonal Interactions and Gut Health 38:32 Optimizing Digestion and Nutrient Absorption 44:23 The Impact of Alcohol on Gut Health 50:51 Promoting Healthy Social Interactions   To learn more about Dr. Emaline:Email: emaline.b@vibrant-wellness.com IG: @vibrantlabs Website: https://vibrant-wellness.com/ YouTube: https://www.youtube.com/channel/UCmWuVqgp3_5Hw4l2jFE2KZA Got a question for Dr. Gladden? Submit it using the link below and it might be answered in our next Q&A episode! https://form.typeform.com/to/tIyzUai7? Reach out to us at:    Website: https://gladdenlongevity.com/     Facebook: https://www.facebook.com/Gladdenlongevity/    Instagram: https://www.instagram.com/gladdenlongevity/?hl=en     LinkedIn: https://www.linkedin.com/company/gladdenlongevity    YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw    

My guest is Michael Snyder, PhD, professor of genetics at Stanford and an expert in understanding why people respond differently to various foods, supplements, behavioral and prescription interventions. We discuss how to optimize your health and lifespan according to what type of glucose responder you are, which genes you express, your lifestyle and other factors. Dr. Snyder also explains the key ages when you need to be particularly mindful about following certain health practices. We also discuss how people respond in opposite ways to different fiber types. This episode ought to be of interest and use to anyone seeking to understand their unique biological needs and how to go about meeting those needs. Sponsors AGZ by AG1: https://drinkag1.com/huberman Wealthfront*: https://wealthfront.com/huberman David: https://davidprotein.com/huberman Eight Sleep: https://eightsleep.com/huberman Function: https://functionhealth.com/huberman *This experience may not be representative of the experience of other clients of Wealthfront, and there is no guarantee that all clients will have similar experiences. Cash Account is offered by Wealthfront Brokerage LLC, Member FINRA/SIPC. The Annual Percentage Yield (“APY”) on cash deposits as of December 27,‬ 2024, is representative, subject to change, and requires no minimum. Funds in the Cash Account are swept to partner banks where they earn the variable‭ APY. Promo terms and FDIC coverage conditions apply. Same-day withdrawal or instant payment transfers may be limited by destination institutions, daily transaction caps, and by participating entities such as Wells Fargo, the RTP® Network, and FedNow® Service. New Cash Account deposits are subject to a 2-4 day holding period before becoming available for transfer. Timestamps 00:00 Michael Snyder 03:33 Healthy Glucose Range, Continuous Glucose Monitors CGM, Hemoglobin A1c 09:02 Individual Variability & Food Choice, Glucose Spikes & Sleepiness 12:18 Sponsors: AGZ by AG1 & Wealthfront 15:16 Glucose Spikes, Tools: Post-Meal Brisk Walk; Soleus “Push-Ups”; Exercise Snacks 21:06 Glucose Dysregulation, Diabetes & Sub-Phenotypes, Tool: Larger Morning Meal 28:34 Exercise Timing, Muscle Insulin Resistance 30:49 Diabetes Subtyping, Weight, Glucose Control; Incretins 35:41 GLP-1 Agonists, Diabetes, Tool: Muscle Maintenance & Resistance Training 38:40 Metformin, Berberine, Headaches 41:01 GLP-1 Agonists, Cognition, Longevity, Tool: Habits Support Medication; Cycling 47:41 Subcutaneous vs Visceral Fat, Organ Stress 49:10 Sponsors: David & Eight Sleep 51:58 Meal Timing & Sleep, Tools: Post-Dinner Walk, Routines, Bedtime Consistency 57:16 Microbiome, Immune System & Gut; Diet & Individual Variability 1:02:52 Fiber Types, Cholesterol & Glucose, Polyphenols 1:09:50 Food As Medicine; Fiber, Microbiome & Individual Variability; Probiotics 1:18:48 Sponsor: Function 1:20:35 Profiling Healthy Individuals, Genomes, Wearables 1:26:31 Whole-Body MRIs, Nodules, Healthy Baseline, Early Diagnosis 1:34:07 Sensors, CGM, Sleep, Heart Rate Variability HRV, Tools: Mindset Effects, Increase REM 1:39:30 HRV, Sleep, Exercise, Tool: Long Exhales; Next-Day Excitement & Sleep 1:42:48 Organ Aging, “Ageotypes”; Biological Age vs Chronological Age 1:49:41 Longevity, Health Span, Genetics, Blue Zones 1:52:19 Epigenetics, Viral Infection & Disease 1:58:54 ALS, Heritability; Neuroprotection, Nicotine 2:03:47 Air Quality, Allergies, DEET & Pesticides, Inflammation, Mold; Microplastics 2:15:02 Single-Drop Blood Test & Biomarkers, Wearables, Observational Trials 2:20:33 Acupuncture, Blood Pressure 2:26:40 Immersive Events & Mental Health Benefits 2:34:59 Data, Nutrition & Lifestyle; Siloed Health Care vs Personalized Medicine 2:43:06 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Social Media, Neural Network Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices

Martha Carlin joins the podcast to explore the crucial connection between soil health and our gut ecosystem. As the founder of The BioCollective, a microbiome-focused company advancing cutting-edge science, and BiotiQuest, the first-of-its-kind probiotic line, Martha combines expertise in terrain theory, microbial ecology, and genetic analysis with personal experience and intuition. Her unique approach empowers people to optimize their health by bridging science, nature, and practical wellness strategies… In this conversation, we unpack: The commonalities between various diseases and microbiome health. How to holistically care for your body. The best way to test your gut health. Martha is a systems thinker and self-described ‘Citizen Scientist' whose pioneering work in the microbiome was born from a deeply personal journey. When her husband was diagnosed with Parkinson's disease at just 44, Martha shifted from a thriving career in business strategy and complex problem-solving to explore the uncharted frontier of microbiome science. Without formal training in medicine or microbiology, she harnessed her analytical skills and relentless curiosity to uncover patterns often overlooked by conventional research. Want to keep up with Martha and her work? Click here now!

Episode focus: What GLP‑1 actually is (your body already makes it), when/where it's released, why food noise exists, and practical ways to nudge the same mechanisms without a prescription. Listen for: simple definitions, meal/lifestyle plays that boost satiety signals, and a week‑by‑week experiment plan. Quick Summary GLP‑1 (glucagon‑like peptide‑1) is a peptide hormone your gut releases after you eat. It helps meals feel calmer by slowing stomach emptying, supporting insulin only when glucose is high, and signaling the brain to turn down cravings. Release is biphasic (two waves): a quick early wave soon after food hits the upper small intestine, and a later, longer satiety wave 30–120+ minutes after—especially when meals include protein, some fat, and fermentable/viscous fiber. Food noise is multi‑factor: hyperpalatable foods, fast eating/liquid calories, sleep debt and stress, microbiome shifts, and environment/cues. Meds mute it fast; habits keep it quiet. What it is: a gut‑made peptide hormone that coordinates the after‑meal response. Where it's made: special gut cells called L‑cells (mostly in the ileum and colon). When it's released: Early wave: minutes after you start eating. Late wave: 30–120+ minutes later as nutrients and fiber fermentation products reach the lower gut. What it does: Slows the stomach so fuel trickles in (you feel fuller, longer). Supports insulin only when glucose is high (smaller spikes, gentler landings). Signals the brain via the vagus nerve to turn down “keep eating” urges. Why meds feel stronger: prescription GLP‑1s are engineered to last much longer than your natural hormone. Food/lifestyle can raise your own signals but won't extend them like a drug. Why Food Noise Gets Loud (and Stays Loud) Hyperpalatable foods (sweet+fat+salt+crunch) keep reward circuits fired up. Removing them for 7–14 days usually turns the volume down. Sleep debt & stress: more ghrelin (hunger), less leptin (satiety), and higher reactivity to cues. Meal speed & form: soft/ultra‑processed textures and liquid calories outrun gut signals. Microbiome: low‑fiber patterns → fewer short‑chain fatty acids → weaker late satiety wave. Environment: visual cues, routines, social context, alcohol, and easy access keep the cycle going. Food Levers (Evidence‑Aligned, Practical) 1) Protein‑forward meals (especially breakfast) Aim ≥30 g protein. Whey (if tolerated) is a strong pre‑meal option: 20–30 g, 15–30 min before a carb‑heavy meal. Why it works: raises satiety hormones (including GLP‑1 and PYY) and lowers “hunt for more” at the next meal. 2) Viscous & fermentable fibers Viscous (slows the meal): oats/barley (beta‑glucan), legumes, chia/flax, okra, eggplant. Fermentable (late‑wave satiety): beans/lentils; cooked‑then‑cooled potatoes/rice (resistant starch); green bananas/plantains; Jerusalem artichokes/asparagus (inulin). Supplements (optional, measured): Psyllium 5–10 g in 12–16 oz water 10–15 min pre‑meal (start with 2–3 g). PHGG (partially hydrolyzed guar gum) 5–10 g/day (gentle fermentable fiber). Glucomannan or inulin/FOS (build slowly; watch GI tolerance). 3) Some fat with meals Sources: eggs, salmon, olive oil, avocado, nuts/seeds. Why it works: helps release bile and triggers fullness signals; supports slower stomach emptying when paired with protein and fiber. 4) Bitter & spicy nudges (optional) Bitter greens (arugula, radicchio), citrus pith, dark cocoa. Capsaicin (chili peppers) or capsinoids (non‑pungent pepper extracts). Start small to check tolerance. 5) Meal order & pace Water/salad/broth first, then protein + veg, then starch. Minimum 15–20 minutes per meal; chew well. Optional: 1–2 tsp vinegar in plenty of water before higher‑starch meals (skip if reflux or enamel sensitivity). Lifestyle Levers (That Amplify Satiety Signals) Vigorous exercise windows: hard sessions can suppress appetite acutely for 1–3 hours; follow with protein + viscous fiber to extend satiety. Sleep 7–9 hours: normalizes hunger/satiety hormones and reduces cue‑reactivity. Early time‑restricted eating: a daytime 8–10 hour window often eases appetite even at similar calories. Environment design: strip hyperpalatables, reduce visible cues, pre‑portion foods, limit variety within a meal.