Podcasts about lifespan

If anyone tells you that they’re not even a little bit insecure, they’re lying, in denial, or both. It’s a fact of life that we all feel insecure at times - about how we look, behave, our achievements, and whether we are liked by others. In this episode, we examine the psychology behind common insecurities, recognise how we can be our own worst enemies, and consider the ways we can come to accept that we are all flawed, and might not actually need ‘fixing’. We unpack: • The surprising evolutionary benefits that come with insecurity• How our levels of insecurity change throughout our lives• The ‘liking gap’, and why we think others like us less than they do • How being insecure can feed insecurity, in a vicious cycle • Why people pleasing and over confidence are often signs of insecurity • How we can address insecurities that negatively impact our lives Watch on Netflix: HERE Follow Jemma on Instagram: @jemmasbeg Follow the podcast on Instagram: @thatpsychologypodcast Subscribe on Substack: @thepsychologyofyour20s For business: psychologyofyour20s@gmail.com Our favourite sources: https://www.bps.org.uk/research-digest/insecurity-leads-us-underestimate-how-much-others-us https://www.researchgate.net/publication/228079585_Self-Esteem_Development_Across_the_Lifespan https://www.centerforanxiety.org/what-is-hyper-independence-is-it-a-bad-thing/ The Psychology of your 20s is not a substitute for professional mental health help. If you are struggling, distressed or require personalised advice, please reach out to your doctor or a licensed psychologist. See omnystudio.com/listener for privacy information.

Advantages of time-restricted eating for body and brain; Dermatologist tells her patient to stay away from hair supplements; Do you still need colonoscopies past 75? How much NTFactor should you take? Breathing CO2 clears brain of amyloid plaque; Popular AI diet tracking apps may underestimate by as much as 345 calories; A novel treatment for knee pain—fiber! Vitamin D slows biological aging.

Life is longer for “those who think young”; Watching too much TV may shrink your brain (literally!); Diet and supplements may help lupus; When a high-fiber diet before surgery may be inadvisable; Your mouth may be the gateway to your overall health and longevity.

Jeff Kowal discusses why healthspan matters just as much as lifespan and touches on baby boomers buying bigger homes instead of downsizing. Later Anthony Priester joins to shed light on senior scams and what to look out for. Then Jeff examines America's most generous 401k plans and wraps up the show with the great wealth transfer.

Leyla Muedin, a registered dietitian nutritionist in New York City, discusses the growing shift from symptom-only “sick care” to a clinically grounded holistic approach to health and recovery. She argues that self-guided wellness routines can leave gaps when underlying medical issues, mental health conditions, substance use disorders, or trauma remain unaddressed, and emphasizes integrating evidence-based clinical evaluation (including labs and deficiency testing) with lifestyle practices. She explains how treating symptoms in isolation misses connections (e.g., stress, sleep, grief) and defines true holistic care as addressing physical, mental, emotional, relational, environmental, and purpose-related factors without rejecting medical treatment. Key components include consistent movement, individualized nutrition built on basics, nervous system regulation (sleep, nature, breathing, meditation/prayer), meaningful social connection, and a sense of purpose as clinically relevant to resilience.

Gerontologist, Dr. Kerry Burnight, is sparking a global revolution to make older better. Fed up with the fear-driven, anti-aging hysteria, millions of people turn to “Dr. Kerry” for her proven approach to navigating longevity. Her New York Times best-selling book, Joyspan: The Art and Science of Thriving in Life's Second Half is for anyone who is aging - and we are ALL aging.Dr. Burnight taught Geriatric Medicine and Gerontology for 18 years at the University of California, Irvine School of Medicine. Burnight's work has been featured in The New York Times, CBS Mornings, The Guardian, Oprah Daily, BBC News, and Forbes Health.https://www.seniorcareauthority.com/resources/boomers-today/

Is there evidence for statins in the treatment of aortic valve stenosis?How the bacteria behind gum disease can affect heart healthWouldn't it be better to resume taking probiotics after finishing a round of antibiotics?Would it be safe to take olive leaf extract with amoxicillin?I'm considering surgery for varicose veins. Is this just a temporary fix? Can they return?

My 25-year-old son has bipolar disorder and can't tolerate his medications. Any natural recommendations?Is chondroitin effective?  It's in my collagen capsules, which I take to hopefully reduce wrinklesI believe I am still suffering from the negative effects of COVID. What would you suggest I take?

First, we'll tell you why the USS Fort Worth had its lifespan cut short. Then, the local impact of Hurricane Genevieve means dangerously high surf levels. Next, we look into the future of the Downtown La Mesa Trolley Station. And we hear from students from tribal bands and nations who attended arts and culture workshops last week. Plus, we speak to researchers who found a glitch in an anti-theft system on some cars.

Dr. Hoffman continues is conversation with naturopathic gastroenterologist Mark Davis, ND (FABNG).

Naturopathic gastroenterologist Mark Davis, ND (FABNG), discusses his work in fecal microbiota transplantation (FMT), research, and integrative approaches to GI disease. Davis explains FMT history, screening criteria, delivery methods, how it differs from probiotics, and why it is highly effective for recurrent C. difficile (about a 90% durable cure), while noting FDA-approved products (Rebyota, Vowst) and off-label applications. He describes IRB-approved studies on naturopathic care for IBS and ulcerative colitis and a blinded project comparing consistency across 15–20 stool microbiome labs. The conversation covers evidence for diet in IBS/IBD (including SCD and a semi-vegetarian diet), low-FODMAP as a temporary tool, breath testing and relapse in SIBO, helminthic therapy options and legality, targeted probiotics (Saccharomyces boulardii, Akkermansia, soil-based species), enema therapies, indigo naturalis benefits and risks, saffron evidence for mood, telemedicine practice, and a crowdfunding platform for clinical trials.

Dr. Hoffman continues his conversation with Dr. Will Van Derveer and Keith Kurlander, co-authors of “Psychedelic Therapy: A Revolutionary Approach to Restoring Your Mental Health and Reclaiming Your Life.” 

Psychedelic Therapy for Mental Health: Research, Safety, and the Path to FDA Approval: Dr. Will Van Derveer and Keith Kurlander, co-authors of “Psychedelic Therapy: A Revolutionary Approach to Restoring Your Mental Health and Reclaiming Your Life,” reveal the shift from recreational psychedelics to structured, research-based psychedelic-assisted therapy for conditions like PTSD, depression, and anxiety. Van Derveer describes limitations of conventional psychiatry (citing STAR*D remission rates) and his entry into MDMA-assisted PTSD research after promising results. They contrast controlled clinical protocols—screening, preparation, safe setting, trained facilitation, medical monitoring, and post-session integration—with uncontained recreational use. The discussion covers current policy momentum under Trump and RFK Jr., VA interest for veterans, and key agents: ketamine (including abuse risks and clinic-only Spravato), MDMA (phase 3 but not approved in 2024), psilocybin (phase 3, potential FDA approval), LSD (GAD trials), ibogaine (arrhythmia risk, Mexico clinics), ayahuasca, peyote, and microdosing. They also note commercialization, including Eli Lilly's acquisition of a 5-MeO-DMT nasal spray developer, and emphasize an integrative “all-of-the-above” mental health approach.

We're reacting to the viral LeBron James farewell songs that have Laker fans in their feelings as the King officially heads to Philly.

This week's supplement spotlight—spermidine; American Heart Association does a 180° on coffee; How accurate are health tracker wearables for sleep, blood pressure, heart rate? A skin disorder practically no one has heard of is often confused for skin cancer; Vitamin D—what forms and what dosages are optimal? Popular sugar substitutes may be worse for the brain than natural sugar.

Science is conquering diseases—now breakthroughs in gene editing promise to vanquish aging itself; The healing potential of hydrogen; Attending concerts, museums and movies may help keep your body younger; Dr. Jeffrey Bland dishes on the benefits of a new full-spectrum fish oil, Omega-3 Rejuvenate.

What Triggers Age-Related Belly Fat? New Stem Cell Findings and a Nutrition Perspective: Nutritionist Leyla Muedin discusses research from City of Hope (published in Science) on why belly fat increases with age even without major weight gain, emphasizing the health risks of visceral fat as an endocrine organ linked to inflammation, diabetes, heart disease, and accelerated aging. The study suggests aging activates adipocyte progenitor cells (APCs) and produces an age-specific stem cell population called committed preadipocytes (CP-As) that generate new fat cells, with experiments showing older APCs create more fat cells even when transplanted into young mice. Single-cell RNA sequencing identified greater CP-A activity in middle-aged mice and similar cells in higher numbers in middle-aged human tissue. Researchers implicate the LIFR signaling pathway and propose future therapies to block these cells, while Leyla questions root causes and argues metabolic dysfunction—insulin resistance, hyperinsulinemia, high carbohydrate intake, and sedentary behavior—should be addressed nutritionally rather than via a pill.

Caite Corripio: How to Make Your Health Span Match Your Lifespan About Caite Corripio Caite Corripio is a National Board Certified Health and Wellness Coach and co-founder of Healthy and Vibrant, where she helps people create sustainable lifestyle change around metabolic health, weight management, stress, and whole body well-being. She has authored two books, "100 Calorie Snacks" and her newly released "100 Self-Care Practices," and hosts a free monthly wellness webinar for her community. Episode Highlights Health Span Versus Lifespan Caite opens the conversation with a foundational truth about aging: "the goal is that you're healthy" so that health span matches lifespan, rather than spending retirement years cycling through doctor visits instead of living out long-planned goals. The Three Macros Made Simple Caite breaks down nutrition into carbs, protein, and fat using a memorable analogy from Winnie the Pooh, where protein is the slow and steady Eeyore, carbs are the quick-burst energy of Tigger, and healthy fat is the wise old owl who balances the two. Pairing macros together, she explains, prevents the blood sugar spikes that come from eating carbohydrates alone. Sugar Cravings and Self-Awareness Caite speaks candidly about her own history with sugar, sharing that she has "a sugar addiction" and continues to fight for better health every day, even while enjoying a slice of cake on her birthday without spiraling into more sugar. Restoring the System Through Sleep and Stress Management Caite calls sleep "nature's nurse," describing it as the time when the body repairs itself, and encourages listeners to release the badge of honor mentality around running on too little rest. She and Julie also discuss box breathing as a simple reset tool, with Caite walking through the visual of breathing around the four sides of a box to calm the nervous system in moments of stress. Wearables and Intentional Tracking Caite discusses her experience wearing a continuous glucose monitor and an aura ring to understand how food, sleep, and travel affect her body, emphasizing that tracking data only matters when it leads to a change in behavior. Movement and Muscle as Retirement Planning Caite reframes exercise as an investment, noting that adults begin losing eight percent of muscle mass per decade after their thirties, and encourages listeners to build strength for the practical demands of daily life, from carrying luggage to preventing falls. Building an Eating Routine Caite recommends eating every two and a half to three hours in smaller, protein and carb balanced portions rather than one or two large meals, and encourages starting the day with protein within about an hour of waking. Choosing Health as a Daily Choice Caite closes with an empowering reminder that a family history of type two diabetes does not have to be a destiny, and that being healthy is a choice made through consistent, sustainable steps rather than a single overnight change. Key Takeaways Health span should be prioritized alongside lifespan through consistent daily habits Balancing protein, carbs, and healthy fat helps prevent blood sugar spikes Sleep and stress management are foundational tools for restoring the body Wearable data is only valuable when it leads to intentional action Building muscle supports independence and confidence at every stage of life Sustainable change comes from small, repeatable choices rather than overnight transformation Connect with Caite Corripio Website: behealthyandvibrant.com Connect with Julie Riga Stacklist: https://stacklist.app/julieriga #stayoncourse #healthspan #wellnesscoach #selfawareness #healthylifestyle Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

At Lifespan, our mission is to help you and your loved ones live your longest, healthiest lives while supporting medical research into breakthroughs to improve all lives. We're building the world's largest longevity community: Join us at https://lifespan.com. Follow us on YouTube, Apple, and Spotify for new Lifespan episodes every 2 weeks.                                __________________________________________ In this episode of Lifespan, Dr. David Sinclair, A.O., Ph.D. – Professor of Genetics at Harvard Medical School and pioneer in longevity research – explores the science of eye aging, vision loss, and emerging strategies to preserve vision throughout life. Dr. Sinclair shares an exclusive update on ER-100, including his team's successful restoration of vision in non-human primates and the launch of the world's first FDA-cleared age reversal human clinical trial. This Phase 1 clinical trial will evaluate the safety of epigenetic cellular restoration as a therapy. Additionally, drawing on decades of research, Dr. Sinclair explains why the eyes may offer one of the earliest windows into biological aging, how everyday factors such as sleep position, alcohol consumption, and intraocular pressure influence long-term eye health, and what the latest evidence reveals about nutrition, supplements, and the connection between the eyes and the brain. Whether you're interested in longevity, brain health, or protecting your eyesight, this episode provides an evidence-based look at the biology of vision and the future of regenerative medicine.                                __________________________________________ Partners of the Lifespan show help us keep this program freely available as an educational resource while also supporting medical research. We only collaborate with partners whose products are grounded in science and that our team has personally used for years. Our selected partners make it convenient for the Lifespan audience to access the tools and technologies featured in this episode - from exogenous fuel for neurons (Ketone-IQ), to wearables that track recovery, strain, and sleep (WHOOP), to smart devices that measure key health metrics such as visceral fat and muscle mass (Withings). If you'd like to learn more or try these tools: ○ Ketone-IQ: Get 30% off your first monthly order at https://ketone.com/lifespan or with code LIFESPAN ○ WHOOP: Get a free WHOOP band and one month of membership at https://join.whoop.com/LIFESPAN or with code LIFESPAN ○ Withings: Get 10% off smart health devices at https://withings.com/lifespan or with code LIFESPAN                                __________________________________________ Legal & Medical Disclaimers The Lifespan show and all related content are provided for informational and educational purposes only and are not intended as medical advice, diagnosis, or treatment. Nothing presented should be interpreted as a recommendation to diagnose, treat, cure, or prevent any disease or medical condition. This content is not a substitute for professional medical advice, diagnosis, or treatment from a qualified healthcare provider. You should always consult with a licensed physician or other qualified healthcare professional before making decisions about your health, including starting, stopping, or modifying any treatment, supplement, diet, or exercise program. The information shared reflects the views and opinions of the host and guests and is based on the scientific literature, their experience and expertise, and general wellness principles. Listening to or engaging with Lifespan content does not establish a doctor–patient or clinical relationship.  Health and longevity outcomes can vary significantly between individuals. Any references to studies, interventions, products, or protocols are not guarantees of specific results, and individual responses may differ. From time to time, Lifespan may discuss or partner with third-party products or services. These references are provided for informational purposes only and should not be considered medical recommendations or endorsements of efficacy for any individual. Lifespan Foundation is an independent 501(c)(3) non-profit organization whose mission is to support medical research.   The views expressed by Dr. David Sinclair, A.O., Ph.D., are his own and do not represent those of Harvard University, Harvard Medical School, or any affiliated institutions.

My LDL is 421, and I have mild to moderate aortic stenosis. Must I take a statin?Lean Mass Hyper-responders on low carb diets explainedWould you consider writing a book about health in advancing age?A revisit of Dr. Hoffman's published booksWhat is the best dose of lithium orotate for therapeutic benefit?Must I exercise fasted? Why?  

Nature or nurture—which is more important when it comes to health conditions?Would I benefit from taking nattokinase along with my statin?Mechanism of action of nattokinase vs. statin medications on coronary artery health

Your Dog Can't Go to Therapy? Do This Instead | Pet Trauma | Dog Care Did you know that your pet's symptoms aren't just problems to eliminate—they are messages to decode? In this episode of the Meditation Podcast, we sit down with Dr. Jeff Fineman, a veterinarian, molecular biologist, and energy healer with over 40 years of experience. He reveals why conventional training often fails to heal traumatized animals and introduces the "Happiness Protocol"—a revolutionary approach to healing trauma through joy, love, and cellular balance. From healing a cat's life-threatening blood count without drugs to helping a silent, terrified rescue dog find its voice again, Dr. Jeff shares profound insights into the invisible energy that connects us to our animals. Learn how to maximize your pet's joy to upgrade their mitochondria, break the bonds of old trauma, and restore their natural resilience. If you've ever felt helpless watching your anxious or aggressive pet, this conversation will change how you see them forever. Get Dr. Jeff's Free Course & Book Links Below

Your Dog Can't Go to Therapy? Do This Instead | Pet Trauma | Dog Care Did you know that your pet's symptoms aren't just problems to eliminate—they are messages to decode? In this episode of the Meditation Podcast, we sit down with Dr. Jeff Fineman, a veterinarian, molecular biologist, and energy healer with over 40 years of experience. He reveals why conventional training often fails to heal traumatized animals and introduces the "Happiness Protocol"—a revolutionary approach to healing trauma through joy, love, and cellular balance. From healing a cat's life-threatening blood count without drugs to helping a silent, terrified rescue dog find its voice again, Dr. Jeff shares profound insights into the invisible energy that connects us to our animals. Learn how to maximize your pet's joy to upgrade their mitochondria, break the bonds of old trauma, and restore their natural resilience. If you've ever felt helpless watching your anxious or aggressive pet, this conversation will change how you see them forever. Get Dr. Jeff's Free Course & Book Links Below

Dr. Hoffman continues his conversation with board-certified psychiatrist Dr. Susan Trachman, author of “It's Not Just In Your Head.”

The Brain–Body Connection, Gut Health, Stress, and Medical Gaslighting: board-certified psychiatrist Dr. Susan Trachman, author of “It's Not Just In Your Head,” about psychosomatic medicine and the two-way brain–body connection. Trachman explains how patients with complex symptoms are often dismissed as having “medically unexplained symptoms” and discusses medical gaslighting, especially affecting women and people of color, with examples of missed diagnoses. She describes how inflammation, the gut microbiome, leaky gut, diet, probiotics, fermented foods, and even fecal transplants can influence mood and health, and reviews vagus nerve stimulation research. The conversation covers stress effects, including Takotsubo “broken heart” cardiomyopathy, CBT for anxiety, IBS, and pain, the role of sleep and the brain's glymphatic system, pandemic-related mental health and long COVID symptoms, concerns about GLP-1 drugs causing emotional flatness, and careful SSRI tapering to avoid withdrawal. 

Dr. Hoffman continues his conversation with Nikki Schultek, founder of Intracel Research Group and co-founder of the Alzheimer's Pathobiome Initiative.

Can Infections Drive Alzheimer's? Nikki Schultek, founder of Intracel Research Group and co-founder of the Alzheimer's Pathobiome Initiative, details evidence that pathogens may contribute to Alzheimer's and other neurodegenerative and neuroimmune disorders beyond the amyloid hypothesis. Schultek recounts her own misdiagnosed systemic illness with neurodegenerative symptoms, later found to involve Lyme disease, Babesia, and chronic infection with the intracellular respiratory bacterium Chlamydia pneumoniae, treated with combination antibiotics. The discussion covers PANS/PANDAS as an infection-associated pediatric neuropsychiatric condition, parallels with neuroinflammation and blood–brain barrier changes, and a 2023 Alzheimer's & Dementia “research roadmap” documenting 86 infection-associated dementia cases and calling for actionable testing and collaboration. They review links involving herpes viruses, COVID-related cognitive decline, gum pathogen P. gingivalis therapies, and controversies around chronic infection diagnosis and long-term antibiotics, and share resources including alzpi.org, ILADS, MAPS, and Schultek's Pathobiome Research Center at PCOM.

BUFFALO, NY — July 21, 2026 — A new #research paper was #published in Volume 18 of Aging on July 6, 2026, titled “Inhibition of peroxisomal protein PRX-11 promotes longevity in Caenorhabditis elegans via enhancements to mitochondria.” The study was authored by Yash Flora, Dhriti Shastri, Kathryn R. DeLeo, and K. Adam Bohnert from the Department of Biological Sciences, Louisiana State University. Aging is accompanied by the gradual decline of many cellular structures that help maintain healthy tissues and organs. Among these are peroxisomes, which play essential roles in breaking down toxic molecules and metabolizing lipids, and mitochondria, which generate most of the cell's energy. Although these organelles work closely together, little has been known about how changes in one influence the aging of the other. This new study reveals that preserving peroxisomes helps maintain healthier mitochondria and extends lifespan in the nematode Caenorhabditis elegans, providing new insight into how communication between cellular organelles influences aging. In this study, the researchers investigated the function of PRX-11, a peroxisomal protein involved in peroxisome division. Previous work from the group showed that reducing PRX-11 activity prevents the age-related degradation of peroxisomes through a process known as pexophagy and increases lifespan. The new study explored why preserving peroxisomes produces these beneficial effects and found that maintaining peroxisomes also preserves mitochondrial health during aging. The researchers found that animals with reduced PRX-11 activity retained long, interconnected mitochondrial networks that resembled those seen in young adults, whereas normal aging was associated with progressive mitochondrial fragmentation. These preserved mitochondria also accumulated less calcium, generated lower levels of oxidative stress, maintained higher ATP-to-ADP ratios, and were associated with improved locomotor function in older animals. Together, these findings indicate that preventing age-related peroxisome loss supports multiple aspects of mitochondrial function during aging. Full press release - https://www.aging-us.com/news-room/preserving-peroxisomes-helps-maintain-mitochondrial-health-and-extend-lifespan-in-c-elegans DOI - https://doi.org/10.18632/aging.206395 Corresponding author - K. Adam Bohnert - bohnerta@lsu.edu Abstract video - https://www.youtube.com/watch?v=fbcqBsP90CY Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206395 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, cellular aging, lifespan, pexophagy, mitochondrial tubulation, inter-organelle crosstalk To learn more about the journal, please visit https://www.Aging-US.com​​ and connect with us on social media at: Bluesky - https://bsky.app/profile/aging-us.bsky.social ResearchGate - https://www.researchgate.net/journal/Aging-1945-4589 X - https://twitter.com/AgingJrnl Facebook - https://www.facebook.com/AgingUS/ Instagram - https://www.instagram.com/agingjrnl/ LinkedIn - https://www.linkedin.com/company/aging/ Reddit - https://www.reddit.com/user/AgingUS/ Pinterest - https://www.pinterest.com/AgingUS/ YouTube - https://www.youtube.com/@Aging-US Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM

Jen Schriever is a Tony Award–nominated lighting designer working across Broadway, the West End, Off-Broadway, regional theatre, and opera.  Most recently, Schriever received the Drama Desk Award and Outer Critics Circle Award for Outstanding Lighting Design for The Lost Boys at the Palace Theatre, a 12-time Tony Award–nominated production that earned her a Tony Award nomination for Best Lighting Design, shared with co–lighting designer Michael Arden.  She received two Tony nominations for her lighting design of A Strange Loop at the Lyceum Theatre and Death of a Salesman at the Hudson Theatre. She is also an Obie Award-winner for Sustained Excellence in Lighting Design and received an Obie Award Special Citation as part of the creative team and ensemble of A Strange Loop.  On Broadway and in the West End, her work includes Art (Music Box Theatre), Glengarry Glen Ross (Palace Theatre), Eureka Day and Lackawanna Blues (MTC, Samuel J. Friedman Theatre), Death of a Salesman (Hudson Theatre), 1776 and Birthday Candles (American Airlines Theatre), A Strange Loop (Lyceum Theatre, The Barbican), Mother Play; Grand Horizons and What the Constitution Means to Me (Helen Hayes Theater), The Lifespan of a Fact (Studio 54), Eclipsed (Golden Theatre), and John Leguizamo's Ghetto Klown (Lyceum Theatre and HBO).  Off-Broadway and New York credits include Antigone (This Play I Read in High School) and The Other Americans (Public Theater), Strategic Love Play (Audible, Minetta Lane Theatre), Spain (Second Stage, Tony Kiser Theatre), Shhh (Atlantic Theater Company), Power Strip (Lincoln Center Theater, Claire Tow Theater), Usual Girls (Roundabout Theatre Company), Strange Interlude (Irondale Theatre, Transport Group), Emmet Otter's Jug-Band Christmas (New Victory Theater), and Selling Kabul (Playwrights Horizons).  Regionally, her work includes Uncle Vanya (Berkeley Repertory Theatre), Highway Patrol (Goodman Theatre), Hippest Trip: The Soul Train Musical (American Conservatory Theater), A Transparent Musical (Mark Taper Forum), A Strange Loop (Woolly Mammoth Theatre Company). She earned a Helen Hayes award for Private Jones at Signature Theatre DC.  In opera, Schriever has designed A Thousand Splendid Suns (Seattle Opera), Iphigenia (tour), The Pearl Fishers and Die Fledermaus (Metropolitan Opera), and La Traviata, Faust, and A Midsummer Night's Dream at the Mariinsky Theatre in Russia, as well as The Pearl Fishers for English National Opera in London.  Learn more about your ad choices. Visit podcastchoices.com/adchoices

Sponsor Link:NordVPN - Secure your online presence with our exclusive offer for Space Nuts listeners. Check out www.nordvpn.com/spacenuts for details.In this engaging Q&A episode of Space Nuts, Andrew Dunkley and Professor Fred Watson dive into listener inquiries that span the cosmos. From the intriguing concept of black hole evaporation to the mysteries of Jupiter's atmosphere and the latest on the Artemis 2 mission, this episode is packed with fascinating insights and scientific discussions.In this episode:- The mechanics of black hole evaporation and how cosmic microwave background radiation affects their lifespan.- An exploration of Jupiter's thin atmosphere and how it compares to the dense atmospheres of moons like Titan and planets like Venus.- Insights into the Artemis 2 mission and the implications of visual observations of meteorite impacts on the moon's far side.- A look ahead at upcoming solar missions and the cutting-edge technology being deployed to study our sun.- The significance of cosmic rays and their impact on human perception in space.Resources & Links:- [Parker Solar Probe](https://www.nasa.gov/content/parker-solar-probe) - NASA's mission to study the sun's outer atmosphere.- [Artemis Program](https://www.nasa.gov/specials/artemis/) - NASA's initiative to return humans to the moon.- [The Cosmic Microwave Background](https://map.gsfc.nasa.gov/universe/uni_cmb.html) - Understanding the remnants of the Big Bang.- [Titan and Its Atmosphere](https://solarsystem.nasa.gov/planets/titan/overview/) - NASA's insights into Saturn's largest moon.Join Andrew and Fred Watson as they unravel the complexities of space science and encourage curiosity about the universe. Don't forget to send in your questions for future episodes!Become a supporter of this podcast: https://www.spreaker.com/podcast/space-nuts-astronomy-insights-cosmic-discoveries--2631155/support.(00:00) Andrew Dunkley takes audience questions on this week's Space Nuts(02:53) If black holes are colder than cmb, how much does this lengthen(09:12) Fred: Does Jordy have an unusually thin atmosphere for a rocky planet(10:48) Titan has a much higher atmospheric pressure than our own planet Jordy(17:16) Michael from Switzerland claims Artemis 2 astronauts saw meteorite flashes on moon(24:55) Houston has had a main B undervolt problem(25:07) Final question today comes from somebody who forgot to tell us their name(34:04) Andrew Dunkley: Thanks for your company. Bye. You're listening to the Space Nuts podcast

Today, I'm joined by Marco Suvilaakso, co-founder & co-CEO of Nucu.   Swapping wearables for "nearables," Nucu's low-touch ambient sleep monitoring platform gives guardians insight into kids' and teens' rest patterns.   In this episode, we discuss filling the market gap in pediatric sleep.   We also cover:   Building family-focused healthtech Benefits of real-time hypnogram data Avoiding obsession over metrics   Subscribe to the podcast → insider.fitt.co/podcast  Subscribe to our newsletter → insider.fitt.co/subscribe  Follow us on LinkedIn → linkedin.com/company/fittinsider    Nucu's Website: https://nucuhealth.com/  Nucu's Instagram: https://www.instagram.com/nucuhealth/  Nucu's LinkedIn: https://www.linkedin.com/company/nucu/    -   The Fitt Insider Podcast is brought to you by EGYM. Visit EGYM.com to learn more about its smart fitness ecosystem for fitness and health facilities.   Fitt Talent: https://talent.fitt.co/  Consulting: https://consulting.fitt.co/  Investments: https://capital.fitt.co/    Chapters: (00:00) Introduction (01:33) Marco background and Nucu overview (05:15) Kids/teens market gap  (06:30) Customer feedback and shift (09:54) Form factor redesign (11:20) Sleep consciousness building (15:03) Baseline and trend tracking (16:00) Room conditions correlation (18:31) Deep biometric insights (20:00) Training schedule impact (21:15) Lifespan data architecture (24:15) Ecosystem partnerships (26:30) Avoiding obsession over metrics (29:50) Real-time hypnogram data (33:40) Two target audiences (36:00) Research collaborations (37:07) Conclusion

Diets rich in fruits and vegetables preserve brain function—but in vulnerable persons with the ApoE4 “Alzheimer's gene”, more meat staves off decline, contradicting years of recommendations to minimize animal protein; Supplements for adrenal insufficiency; “Forever chemicals” may weaken teen's bones—but menopausal hormone replacement therapy decisively fends off osteoporosis; Legionnaire's disease strikes poor and affluent alike in New York City; Doctors propose warning labels for GLP-1 drugs on account of this under-appreciated danger.

Pentagon plans widespread testosterone screening for troops; New study claims arthroscopic surgery for age-related degenerative changes of knees is worthless; Widely touted “precision” proton therapy doesn't outperform conventional radiation treatment for prostate cancer; Comparing the effectiveness of gummies and liquids vs. tablet or capsule forms of supplements; Supplements to lower LDL; Lithium orotate for Alzheimer's prevention; Novel ultrasound treatment may target inflammation in osteoarthritis; Researchers explore antiviral treatments for multiple sclerosis.  

Get access to more than 200 episodes of my premium podcast (The Aliquot) when you sign up as a FoundMyFitness Premium Member The next 10 years may add decades to human lifespan by compressing the time it takes to understand, treat, and prevent disease. In this episode, Dr. Derya Unutmaz explains why accelerating AI could transform drug discovery, shorten clinical trials, and push cancer treatment toward increasingly personalized interventions. He also reframes AI not as an existential threat, but as a medical enabler that doctors may soon be ethically obligated to use. Timestamps: (00:00) Introduction (07:11) Why the next 10 years may add 50 to your lifespan (11:19) How AI is transforming drug discovery (16:50) Could digital twins shorten clinical trials? (19:25) Can AI predict drug safety and efficacy? (23:40) Have we already reached AGI? (29:23) Why AI may be medicine's greatest force multiplier (35:35) Can AI replicate a scientist's biological intuition? (42:16) Is it malpractice for doctors not to use AI? (48:18) What happens when AI monitors disease in real time? (51:52) Which AI models should doctors trust? (57:29) Claude vs. GPT—does the model matter for diagnosis? (1:00:58) Generalist vs. specialized AI—which works better in medicine? (1:04:25) Why cancer is so hard to cure (1:08:18) Could cancer be curable within a decade? (1:12:29) Can AI design cancer treatments on demand? (1:14:31) How AI could curb overtreatment and side effects (1:17:28) Predicting cancer years before it forms—is it possible? (1:23:50) Why biology could go exponential with AI (1:28:58) Why aging may be easier to prevent than reverse (1:34:51) Can the body be engineered to resist aging? (1:40:07) Can AI model how gene therapy will behave? (1:44:12) What people who reach 110+ reveal about Human 2.0 (1:46:21) From Dolly to Yamanaka factors—the case for cellular age reversal (1:50:56) Why full-body rejuvenation is an engineering problem (1:58:44) What happens when AI reasons longer about biology? (2:01:25) The biosecurity dilemma of powerful AI (2:06:12) What should we actually measure to track aging? (2:12:34) How old immune cells distort aging clocks (2:15:22) Why reversing brain aging is uniquely difficult (2:21:49) The ultimate prompt for extending lifespan (2:23:50) What data does a true digital twin need? (2:28:32) How to build a mini digital twin today (2:33:26) How to give AI a long-term memory of your data (2:36:33) Why personal baselines matter for AI advice Show notes are available by clicking here Watch this episode on YouTube

Vitamin B12 Deficiency--The “Aging” Symptoms You Shouldn't Ignore: Leyla Muedin, a registered dietitian nutritionist in New York City, discusses vitamin B12 deficiency as a common problem that can mimic normal aging, noting adults need only about two micrograms daily to support red blood cells, nerves, and DNA. She reviews the history of liver treatment for pernicious anemia and explains that deficiency remains common in older adults, vegans/vegetarians, and people with impaired absorption due to low stomach acid, autoimmune gastritis, weight loss surgery, or medications such as metformin and proton pump inhibitors. Symptoms can develop slowly and include fatigue, weakness, shortness of breath, numbness/tingling, poor balance, memory issues, and brain fog; she advises medical evaluation and B12 testing rather than assuming aging or relying on wellness-clinic injections when levels are normal. She emphasizes B12 is primarily in animal foods, so vegans need supplements, and notes broader nutrient shortfalls she sees in vegan clients.

Does coffee really dehydrate you? A deeper dive on this important topicHelp for nighttime urinationPlease discuss aortic dissection

How do I find a preventive cardiologist in northern New Jersey?What is the best supplement for dissolving bone spurs?What is the half-life of vitamin D, either by supplement or sun exposure?What do you think about mushroom coffee? Does it have any health benefits?Please discuss how strontium affects DEXA scan results

Dr. Hoffman continues his conversation with Dr. David Chernoff, Chief Medical Officer of Setpoint Medical.

Dr. David Chernoff, Chief Medical Officer of Setpoint Medical, discusses electrically driven vagus nerve stimulation (VNS) as a “neuroimmune modulation” approach to autoimmune and inflammatory disease. Chernoff explains the vagus nerve's sensory role in monitoring organs and signaling the brainstem and spleen to regulate immune responses, and how precise stimulation can reduce pro-inflammatory cytokines without immunosuppression. Setpoint's miniaturized, wireless, MRI-compatible implant is placed in an outpatient 45-minute neck procedure and delivers one minute of daily stimulation titrated to an upper comfort level; long-term safety is supported by prior surgical experience and a 242-patient blinded RA study with two-year data, leading to FDA approval for rheumatoid arthritis. The discussion covers add-on use with medications, potential steroid tapering, reimbursement, and research in Crohn's disease, relapsing MS (vision and remyelination), and other conditions, including psoriatic arthritis, lupus, and neurodegenerative diseases.

Discussion Highlights: the importance of precision medicine as the intersection of biology, lifestyle, and environment, influenced by both genetic predispositions and external factors the complexity of choosing appropriate tests and the need for expertise in interpreting results the gap between standard laboratory testing and deeper molecular analysis needed for precision health the need to equip doctors with tools to interpret multi-omic data as AI becomes more prevalent in healthcare the concept of a "biological 401(k)" to describe the daily deposits and withdrawals of bioenergetic currency, including diet, exercise, sleep, nutrition, meaning, purpose, and environment, which contribute to overall health resilience the importance of understanding and addressing root causes of health issues rather than just treating symptoms Dr. Anil Bajnath is the Founder & President of the American Board of Precision Medicine, author of The Longevity Equation, and a board-certified physician specializing in precision and longevity medicine. His clinical practice is built around root-cause resolution, translating genetics, advanced biomarker analysis, and individualized nutrition into frameworks real people can use. He's known for helping patients and practitioners turn complex data into practical action and lasting lifestyle change. Learn more at ifho.org and follow Dr. Bajnath on Instagram @dranilbajnath Visit ConfidenceThroughHealth.com to find discounts to some of our favorite products.Follow me via All In Health and Wellness on Facebook or Instagram.Find my books on Amazon: No More Sugar Coating: Finding Your Happiness in a Crowded World and Confidence Through Health: Live the Healthy Lifestyle God DesignedProduction credit: Social Media Cowboys

I sat down with Dr. Jordan Metzl, a sports-medicine physician who's convinced that the reason most of us can't stay consistent isn't discipline or knowledge, it's motivation, and he says you can actually engineer it by "lowering the cost to act." We get into exercise as a literal medicine that would beat almost any drug if it came in a pill, why fun is the real holy grail of compliance, and how movement can go head-to-head with antidepressants for everyday anxiety and depression. If you've been white-knuckling your way through willpower and losing, this one's going to change how you think about getting off the couch. CLICK HERE TO BECOME GARY'S VIP!: https://bit.ly/4ai0Xwg Get Dr. Jordan Metzl's book, “Push: Unlock the Science of Fitness Motivation to Embrace Health and Longevity”: https://bit.ly/4f28xiO Connect with Dr. Jordan Metzl Website: https://bit.ly/4gzA0tp  Instagram: https://bit.ly/4aRhbhA  Facebook: https://bit.ly/4fdR45E  X: https://bit.ly/4aP5Mig   Thank you to our partners A-GAME: “ULTIMATE15” FOR 15% OFF: http://bit.ly/4kek1ij AION: “ULTIMATE10” FOR 10% OFF: https://bit.ly/4h6KHAD AIRES: "ULTIMATE20 " FOR 20% OFF: https://bit.ly/4a3Duze BAJA GOLD: "ULTIMATE10" FOR 10% OFF: https://bit.ly/3WSBqUa BODYHEALTH: “ULTIMATE20” FOR 20% OFF: http://bit.ly/4e5IjsV COLD LIFE: THE ULTIMATE HUMAN PLUNGE: https://bit.ly/4eULUKp CYMBIOTIKA: "ULTIMATE20" FOR 20% OFF: https://bit.ly/4tjyluP GENETIC METHYLATION TEST (UK ONLY): https://bit.ly/48QJJrk GENETIC TEST (USA ONLY): ⁠https://bit.ly/3Yg1Uk9 GOPUFF: GET YOUR FAVORITE SNACK!: https://bit.ly/4obIFDC H2TAB: “ULTIMATE10” FOR 10% OFF: https://bit.ly/4hMNdgg HEALF: 10% OFF YOUR ORDER: https://bit.ly/41HJg6S PEPTUAL: “TUH10” FOR 10% OFF: https://bit.ly/4mKxgcn SNOOZE: LET'S GET TO SLEEP!: https://bit.ly/4pt1T6V WHOOP: JOIN & GET 1 FREE MONTH!: https://bit.ly/3VQ0nzW Watch  the “Ultimate Human Podcast” every Tuesday & Thursday at 9AM EST: YouTube: https://bit.ly/3RPQYX8 Podcasts: https://bit.ly/3RQftU0 Connect with Gary Brecka Instagram: https://bit.ly/3RPpnFs TikTok: https://bit.ly/4coJ8fo X: https://bit.ly/3Opc8tf Facebook: https://bit.ly/464VA1H LinkedIn: https://bit.ly/4hH7Ri2 Website: https://bit.ly/4eLDbdU Merch: https://bit.ly/4aBpOM1 Newsletter: https://bit.ly/47ejrws Ask Gary: https://bit.ly/3PEAJuG Timestamps 00:00 - ​Intro of Show 02:00 - From family of doctors to sports medicine 04:00 - Prescribing the medicine of exercise 05:55 - What an exercise prescription looks like 07:41 - The 1950s London Transport study 10:22 - Cellular adaptations and mitochondria 11:52 - Inflammation and chronic disease 13:31 - Immuno-fatigue and the theory of aging 14:45 - Motivation, not discipline, is missing 18:14 - Knowledge, emotion, and belief 20:25 - Building a fitness community 24:11 - Biomarkers and the cost of chronic disease 26:23 - Lifespan vs healthspan gap 28:26 - Fun is the holy grail of compliance 34:00 - Why remote work hurts our health 39:16 - Making exercise pay for doctors 41:01 - Two minutes of vigorous activity a day 44:30 - The GLP-1 and arthritic knee study 48:49 - Exercise vs antidepressants 55:38 - Lowering the cost to act 59:42 - What it means to be an Ultimate Human 1:01:29 - Alice: a marathon at 70 Disclaimer: This podcast is for informational purposes only and does not provide medical advice. It is not intended for diagnosing or treating any health condition. Always consult a licensed healthcare professional before making health or wellness decisions.  Gary Brecka is the owner of Ultimate Human, LLC which operates The Ultimate Human podcast and promotes certain third-party products used by Gary Brecka in his personal health and wellness protocols and daily life and for which Ultimate Human LLC and / or Gary Brecka directly or indirectly holds an economic interest or receives compensation.  Accordingly, statements made by Gary Brecka and others (including on The Ultimate Human podcast) may be considered promotional in nature. Learn more about your ad choices. Visit megaphone.fm/adchoices

Dr. Hoffman continues his conversation Jim LaValle, a clinical pharmacist, author, and board-certified clinical nutritionist.

 Mushrooms for Sleep and Cognitive Support: Jim LaValle, a clinical pharmacist, author, and board-certified clinical nutritionist, details Wakunaga/Kyolic's new Specialty Series mushroom products and related health strategies. He reveals a sleep formula with reishi, L-theanine, valerian, and Aged Garlic Extract aimed at calming stress and supporting better sleep. The formula for cognition includes lion's mane for memory support and aronia berry antioxidants. He also emphasizes Aged Garlic Extract's heart benefits. 

Dr. Alan Castel, PhD, is a professor of psychology at the University of California, Los Angeles (UCLA) and one of the world's foremost experts on human memory and cognitive aging. We discuss what science actually tells us about how to improve our learning ability and memory at any age. We also discuss how memory works, why all planning and imagination about the future is based on the past, false memories, and how to leverage curiosity, emotion, and self-testing retrieval practice to stamp in memories for the long term. We discuss what "superagers"—people who actually improve their cognitive capacity with age—do differently than everyone else. This episode is for anyone interested in the science of memory and tools to maintain and improve your memory across the lifespan. Thank you to our sponsors AG1: https://drinkag1.com/huberman Wealthfront*: https://wealthfront.com/huberman Helix Sleep: https://helixsleep.com/huberman Function: https://functionhealth.com/huberman Lingo: https://hellolingo.com/huberman Timestamps (00:00:00) Dr. Alan Castel (00:02:41) What Is Memory?, Reconstruction & Metacognition (00:04:49) Mnemonics, Remembering Names & Deeper Learning (00:08:22) The Penny & Apple Logo, Noticing vs Seeing, Learning Through Mistakes (00:10:43) Sponsors: Wealthfront & Helix (00:14:05) Neuroplasticity, Frustration, Curiosity & Mindset (00:17:42) Maintaining vs Learning New Things, Habits, Novelty & Emotional Memory (00:24:28) "Mental Photographs," Photo-Taking & Imagining the Future (00:29:28) Eyewitness Memory, the Ronald Cotton Case, Confidence vs Accuracy (00:35:07) Medium-Term & Prospective Memory, Hotel Fire Exits (00:40:28) Sponsor: AG1 (00:41:47) When Habits Turn Lethal, Aviation & Human Error (00:49:01) Why Memory Changes With Age; Alzheimer's & the Nun Study (00:52:34) Exercise & Hippocampal Volume, Falls & Balance (00:57:14) SuperAgers & Athletes; Regret, Balance & Being Driven (01:12:08) Sponsor: Function (01:13:45) Age Stereotypes, Subjective Age & Positive Age Beliefs (01:20:02) Goals & Plans, Scams; Anterior Midcingulate Cortex & SuperAgers (01:26:23) Culture, Resilience, Blue Zones & COVID (01:29:18) Adversity, the Positivity Effect & Intergenerational Learning (01:36:31) Sponsor: Lingo (01:38:00) Limitations & Purpose; Time, Family & Connection (01:44:58) Deliberately Building Memories; the ABCs of Successful Aging (01:51:02) Following Your Interests; Castel's Path & Older Adults (01:57:16) Mental Simulations, Curiosity Studies & Selectivity (02:01:19) Socioemotional Selectivity Theory; Steve Jobs & Lifespan (02:07:10) The Secret to Successful Aging; State vs Trait Curiosity (02:11:04) Scams & AI Voice Cloning (02:14:31) John Wooden, Wisdom, Love & Balance (02:17:41) Learning Through Mistakes; Does the Brain Get Better With Age? (02:25:00) Conclusion, Better With Age (02:26:00) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures *This experience may not be representative of other Wealthfront clients, and there is no guarantee of future performance or success. Experiences will vary. Andrew Huberman receives cash compensation from Wealthfront Brokerage for paid testimonials in his podcast, creating a conflict of interest. The Cash Account, which is not a deposit account, is offered by Wealthfront Brokerage LLC, member FINRA/SIPC. Wealthfront Brokerage is not a bank. The base APY is 3.30% on cash deposits as of January 30, 2026, is representative, subject to change, and requires no minimum. If eligible for the overall boosted rate of 4.05% offered in connection with this promo, your boosted rate is also subject to change if the base rate decreases during the 3 month promo period. Additional terms and conditions apply, which can be found on Wealthfront.com/Huberman. Funds in the Cash Account are swept to program banks, where it earns the variable APY. Same-day withdrawal or instant payment transfers may be limited by destination institutions, daily transaction caps, and by participating entities such as Wells Fargo, the RTP® Network, and FedNow® Service. New Cash Account deposits are subject to a 2-4 day holding period before becoming available for transfer. Investment advisory services are provided by Wealthfront Advisers LLC, an SEC-registered investment adviser. Securities investments: not bank deposits, bank-guaranteed or FDIC-insured, and may lose value. Learn more about your ad choices. Visit megaphone.fm/adchoices

Is it safe to stop statins “cold turkey”? Can the supplement ingredient HMB counteract age-related muscle loss? Researchers may have discovered the key to development of a true fat-burning weight loss medication; Can a mammogram yield clues about cardiovascular risk? Their bottom line threatened by GLP-1 weight loss drugs, BIg Food tweaks portion sizes, adds spices and flavorings to pique blunted appetites; Vitamins A & D may improve lung health for asthma sufferers; When it comes to thyroid medication prescribing, treat the numbers or treat the patient? 

Carnitine, with acknowledged muscle and brain benefits, may find a new role in supporting cancer immunity; Calcium and vitamin D's bone-building impact may be limited; Internal visceral fat may accelerate brain aging, MRI study finds; The remarkable benefits of a newly-discovered mitochondrial booster—urolithin A (Mitopure®️).

APR Health Solutions Peptides: www.aprhealthsolutions.com - code nyleOptimize HRT Clinic: https://members.optimize-hp.com - code nyleMerch: https://www.aykons.com/nylePlease share this episode if you liked it. To support the podcast, the best cost-free way is to subscribe and please rate the podcast 5* wherever you find your podcasts. Thanks for watching.To be part of any Q&A, follow trensparentpodcast or nylenayga on instagram and watch for Q&A prompts on the story  https://www.instagram.com/trensparentpodcast/Huge Supplements (Protein, Pre, Defend Cycle Support, Utilize GDA, Vital, Astragalus, Citrus Bergamot): https://www.hugesupplements.com/discount/NYLESupport code 'nyle' 10% off - proceeds go towards upgrading content productionYoungLA Clothes: https://www.youngla.com/discount/nyleCode ‘nyle' to support the podcastLet's chat about the Podcast:Instagram: https://www.instagram.com/trensparentpodcast/TikTok: https://www.tiktok.com/@transparentpodcastPersonalized Bodybuilding Program:  https://www.nylenaygafitness.comRP Hypertrophy Training App: rpstrength.com/nyle (code nyle)Timestamps:00:00:00 - Intro00:01:39 - Medical Tourism: Hair Transplants & Teeth00:04:06 - Why Athletes Go to Turkey for Heart Scans00:06:15 - The Galleri Test: Preemptive Cancer Screening00:09:09 - Genetic Limits vs. Mega-Dosing Gear00:14:33 - Protecting Your Fertility on Cycle00:17:24 - Left Ventricular Hypertrophy in Bodybuilders00:19:22 - Top 5 Longevity & Health Supplements00:23:40 - Detecting Hidden Insulin Resistance00:26:15 - How to Fix a Fatty Liver00:29:52 - Endothelium: The Root of Heart Disease00:32:43 - Why ApoB Matters More Than LDL00:38:06 - The Danger of Dumping Blood (Phlebotomy)00:43:54 - Calcium Scores vs. CT Angiograms00:58:48 - Brain Farts, ADHD, & Sleep Hygiene01:02:26 - The Truth About Research Peptides01:09:19 - Curing Leaky Gut & GI Issues01:11:02 - Safe Gear & Insulin for Women01:16:58 - Navigating Female Endocrine Preservation01:20:57 - Toxic Coaching & Client Caps01:22:06 - Broderick Chavez & Cycle Philosophies01:26:30 - Structuring a 16-Week Off-Season01:33:42 - The Importance of Bridge Phases01:40:06 - Muscle Memory & First Cycle Gains01:49:26 - Breaking Plateaus with Halotestin & Winstrol01:58:27 - Superdrol & Water Retention02:00:12 - IGF-1, HGH, & Tumor Growth02:08:34 - Top 5 Bodybuilding Coaches02:15:20 - Peaking a Type 1 Diabetic02:18:41 - Fixing Chronic IBS02:20:23 - The Truth About Follistatin02:25:20 - Controlling Your Waistline in the Off-Season02:36:05 - Retatrutide vs. Semaglutide02:39:33 - Women's Physique vs. Female Bodybuilding02:48:08 - Final Message: Your Future Self

At Lifespan, our mission is to help you and your loved ones live your longest, healthiest lives - while supporting medical research into breakthroughs to improve all lives. We're building the world's largest longevity community: Join us at https://lifespan.com. Follow us on YouTube, Apple, and Spotify for new Lifespan episodes every 2 weeks.                               __________________________________________ In this second installment of Lifespan's two-part series on calorie restriction and fasting, Dr. David Sinclair, A.O., Ph.D.  – Professor of Genetics at Harvard Medical School and a pioneer in longevity research – explores how to fast effectively for health and longevity. Drawing on decades of research and the latest scientific evidence, Dr. Sinclair explains how to approach fasting effectively, what happens inside your body at the 12-, 24-, and 48+-hour marks, how to overcome common plateaus, and the key considerations for women, men, and people at different stages of life.  Whether you're new to fasting or looking to refine your approach, this episode provides a practical, evidence-based guide to using fasting to support metabolism, cellular repair, and healthy longevity.                                __________________________________________ Partners of the Lifespan show help us keep this program freely available as an educational resource while also supporting medical research. We only collaborate with partners whose products are grounded in science and that our team has personally used for years. Our selected partners make it convenient for the Lifespan audience to access the tools and technologies featured in this episode - from exogenous fuel for neurons (Ketone-IQ), to wearables that track recovery, strain, and sleep (WHOOP), to smart devices that measure key health metrics such as visceral fat and muscle mass (Withings). If you'd like to learn more or try these tools: ○ Ketone-IQ: Get 30% off your first monthly order at https://ketone.com/lifespan or with code LIFESPAN ○ WHOOP: Get a free WHOOP band and one month of membership at https://join.whoop.com/LIFESPAN or with code LIFESPAN ○ Withings: Get 10% off smart health devices at https://withings.com/lifespan or with code LIFESPAN                                __________________________________________ Legal & Medical Disclaimers The Lifespan show and all related content are provided for informational and educational purposes only and are not intended as medical advice, diagnosis, or treatment. Nothing presented should be interpreted as a recommendation to diagnose, treat, cure, or prevent any disease or medical condition. This content is not a substitute for professional medical advice, diagnosis, or treatment from a qualified healthcare provider. You should always consult with a licensed physician or other qualified healthcare professional before making decisions about your health, including starting, stopping, or modifying any treatment, supplement, diet, or exercise program. The information shared reflects the views and opinions of the host and guests and is based on the scientific literature, their experience and expertise, and general wellness principles. Listening to or engaging with Lifespan content does not establish a doctor–patient or clinical relationship.  Health and longevity outcomes can vary significantly between individuals. Any references to studies, interventions, products, or protocols are not guarantees of specific results, and individual responses may differ. From time to time, Lifespan may discuss or partner with third-party products or services. These references are provided for informational purposes only and should not be considered medical recommendations or endorsements of efficacy for any individual. Lifespan Foundation is an independent 501(c)(3) non-profit organization whose mission is to support medical research.   The views expressed by Dr. David Sinclair, A.O., Ph.D., are his own and do not represent those of Harvard University, Harvard Medical School, or any affiliated institutions.

Pre-order Keto Flex Revised and get free bonuses at: https://bit.ly/4wKG1sM Everyone's chasing longevity — more years, anti-aging, living longer. Ben Azadi says that's the wrong goal, and quietly chasing it may be destroying the years you actually get. In this episode, Ben and Alex break down the difference almost nobody talks about: lifespan vs. healthspan. Modern medicine is great at adding years. But adding years you spend inflamed, medicated, and dependent isn't living — it's just declining slower. The real goal was never a longer life. It's a life you can actually enjoy: energy, mobility, and showing up for the people you love. What we get into: Lifespan vs. healthspan, and why extending your life means little if the quality collapses The "take less hits" principle (what Jordan, Kobe, and Brady all figured out) and how it applies to your daily choices Why your symptoms — brain fog, achy joints, belly fat, bloating — aren't the problem, they're your body's check engine light How the damage compounds: it starts as whispers, then your body starts screaming (Sandra's story: 40 wishes vs. one) Why not prioritizing your health is one of the most selfish things you can do, and who really pays the price Common vs. normal: aging is inevitable, but suffering isn't, and how your cellular age can actually be reversed The comfort trap, and how Gail broke out of it, losing 120 lbs and getting her independence back The "medication deficiency" myth, and why only 2 countries on earth allow pharma ads on TV One line to remember: "If you treat your health casually, you'll end up a casualty." Find All The Ben Azadi Show Sponsorship Deals https://www.ketokamp.com/sponsorship-deals Ben's website: http://www.benazadi.com