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It's Tuesday, October 21st, A.D. 2025. This is The Worldview in 5 Minutes heard on 140 radio stations and at www.TheWorldview.com.  I'm Adam McManus. (Adam@TheWorldview.com) By Kevin Swanson                    Xi Jinping fired 9 Chinese military commanders China's communist system is in turmoil, as the defense ministry announces the removal of nine very senior military commanders from duty, including a number two general, He Weidong. Since 2023, the communist leader, Xi Jinping, has administered the removal of dozens of senior officers. These moves signal a factionalism from within the party and the Chinese military. Experts question whether Jinping will survive in his position. This week, the Central Committee of the Communist Party of China is holding its Fourth Plenary Session where leaders will work out a Five-Year Plan. The outcome of this meeting will reveal Jinping's standing in party politics. Keep in mind: God is in control. Haggai 2:22 says, “The word of the Lord came unto Haggai … I will overthrow the throne of kingdoms. … I will overthrow the chariots, and those that ride in them; and the horses and their riders shall come down, everyone by the sword of his brother.” Pakistani pastor survives murder plot A Pakistani pastor survived a murder attempt in Islamabad, the capital of Pakistan, on the morning of Sunday, September 21, reports Barnabas Aid. Pastor Kamran Naz had been traveling by bus, accompanied by his mother, from his home in Gujranwala to lead a church service in Islamabad when he was attacked by two unidentified gunmen. One bullet wounded the pastor in the right leg. A second bullet narrowly missed his head. The attackers then fled on a motorcycle as some church members who were present swiftly came to the pastor's aid and contacted emergency services. Pastor Kamran had previously notified the police of numerous death threats. He was warned to stop ministering at the church or face the consequences.  Pastor Imran Amanat, leader of the Christian advocacy group LEAD Ministries Pakistan, said, “We will not be intimidated or silenced. We demand that the authorities immediately ensure the protection of Christian leaders and hold the criminals accountable. If the government continues to ignore these threats, it becomes complicit in the persecution.” According to Open Doors, Pakistan is the eighth most dangerous country worldwide for Christians. Swedish parents lost custody over kids' required church attendance Certain European nations have now been recognized for their systemic violation of parental rights, especially if the parents happen to be Christian.  Alliance Defending Freedom International is working on a case in Sweden, where parents have lost custody of their children under charges of “religious extremism.” The parents had simply restricted the phone use of their teen children and required attendance at church meetings. After three years of attempts to regain custody, Daniel and Bianca Samson are appealing their case to the European Court of Human Rights. Recently, the High Court has already condemned countries like Spain, Portugal, Italy, Croatia, and Romania for systemic violations in family separation and child welfare cases. Iran threatens Israel Iran's Ayatollah Ali Khamenei took to social media (X) yesterday, effectively taunting the American government, threatening Israel, and asserting independence for the nation's nuclear program. He asked, “What authority do you, Americans, have to dictate what a country should or shouldn't do if it possesses nuclear industry? What position do you hold in the world? How is it any of America's business whether Iran has nuclear capabilities and nuclear industry or not? .. . The U.S. President boasts that they've bombed and destroyed Iran's nuclear industry. Very well, in your dreams!” Trump urges Putin and Zelenskyy to end the war President Donald Trump is urging Ukraine's leader, Volodymyr Zelenskyy to end the war on Russia's terms.  He warned Zelenskyy of Russian President Vladimir Putin's threat to “destroy” Ukraine it there is no agreement.  The Financial Times described the meeting as a “shouting match”, with Trump throwing maps in the room, and “cursing all the time.” Japan greenlights Morning After Pill Japan has just approved the abortifacient drug known as the over-the-counter “morning after” pill. Japan also approved the RU-486 abortion kill pill back in April 2023. Japan recorded 686,000 births in 2024. That's down from 762,000 in 2023, and down from 2,000,000 in 1975. Jeremiah 32:35 speaks of this child sacrifice.  “They built the high places of Baal in the Valley of the Son of Hinnom, to offer up their sons and daughters to Molech, though I did not command them, nor did it enter into my mind, that they should do this abomination.” Day 21 of U.S. government shutdown The U.S. government shutdown is rounding its 21st day. With 900,000 employees furloughed, the shutdown represents the most severe in American history.  Indeed, 7,850 flights were delayed due to air traffic control staffing shortages on Sunday.  According to TheHill.com, 13,000 air traffic controllers and 50,000 TSA agents are presently working without pay. Housing bubble has burst The housing bubble has burst in multiple cities across the United States. The median house values in Oakland, California and Austin, Texas have dropped by 24% since the peak in 2022. Significant declines have also been reported in New Orleans, San Francisco, Fort Myers, Florida, and Denver, Colorado, reports WolfStreet.com. Gold and silver hit new record highs Metals continued their journey upwards and onwards in Monday's market activity. Gold hit $4,350 per ounce and silver hit $52 and change per ounce, reports Reuters. Trump's Education Dept. funds conservative ideology at colleges The Trump Education Department is offering preferential funding for those universities willing to bend more conservative. Only Vanderbilt, the University of Arizona, and the University of Texas at Austin have embraced to the idea out of the nine universities approached with the proposal, reports Breitbart.  MIT, Brown University, the University of Pennsylvania, and the University of Southern California have all rejected the Trump administration's encouragement to abolish their departments opposed to conservative ideas.  Major jewel heist at Louvre in Paris, France And finally, a team of four thieves broke into the Louvre Museum in Paris over the weekend. They stole priceless jewels dating back to the 19th Century, reports Reuters. Among the stolen items were a tiara and brooch belonging to Empress Eugénie, wife of Napoleon III, an emerald necklace and a pair of emerald earrings from Empress Marie Louise, Napolean's second wife, and a tiara, a necklace, and single earring from the sapphire set that belonged to Queen Marie-Amelie and Queen Hortense. (Also a brooch known as the "reliquary brooch” was taken). Close And that's The Worldview on this Tuesday, October 21st, in the year of our Lord 2025. Follow us on X or subscribe for free by Spotify, Amazon Music, or by iTunes or email to our unique Christian newscast at www.TheWorldview.com.  I'm Adam McManus (Adam@TheWorldview.com). Seize the day for Jesus Christ.

Derek Champagne talks with Sramana Mitra. Sramana is the founder and CEO of One Million by One Million (1Mby1M), the world's first and only global virtual incubator/accelerator. Its goal is to help a million entrepreneurs globally reach a million dollars in annual revenue, build a trillion dollars in global GDP, and create 10 million jobs.Since its founding in 2010, 1Mby1M has become a powerful platform for democratization of entrepreneurship acceleration.Sramana also developed 1Mby1M's Incubator-in-a-Box methodology for Corporate Incubation that is used by enterprises to manage internal and external innovation endeavors.In 2015, LinkedIn named Sramana one of their Top 10 Influencers alongside Bill Gates and Richard Branson.Sramana has been an entrepreneur and a strategy consultant in Silicon Valley since 1994. Her fields of experience span from hardcore technology disciplines like Artificial Intelligence, Cloud Computing and Semiconductors, to sophisticated consumer marketing industries including e-commerce, fashion and education.As an entrepreneur CEO, Sramana founded three companies: Dais (off-shore software services), Intarka (sales lead generation and qualification software using Artificial Intelligence algorithms; VC: NEA) and Uuma (online personalized store for selling clothes using Expert Systems software; VC: Redwood). Two of these were acquired, while the third received an acquisition offer from Ralph Lauren which the company did not accept.As strategy consultant, Sramana has consulted with over 80 companies, including public companies such as SAP, Cadence Design Systems, Webex, KLA-Tencor, Best Buy, MercadoLibre and Tessera among others. Her work has also included numerous startups and VCs.Sramana has a Masters degree in EECS from MIT and a Bachelors degree in Computer Science and Economics from Smith College.From 2000 to 2004, Sramana chaired the MIT Club of Northern California's entrepreneurship program in Silicon Valley.Learn more at www.1Mby1M.comBusiness Leadership Series Intro and Outro music provided by Just Off Turner: https://music.apple.com/za/album/the-long-walk-back/268386576

Schild Tamás New Yorkban: A vágóhídtól a balettpróbákig, fotókon az emberi sorsok  

(October 17, 2025)Brown, Penn, USC, & MIT decline White House funding compact; everything we know about the federal funding proposal for universities. California made it through another summer without a Flex alert… thanks batteries, experts say. Beyond Meat's stock collapses after debt deal. Is it okay to decline your airplane seat?

This is a replay of my June 27th conversation with @Sustainabledud1 on all things Rare Earths (REE) ... before they were popular :) I hope you guys enjoy!Remember: EDUCATIONAL PURPOSES ONLY FOLKS. Stoked to have Sustainable Dude on the podcast to dive deep into the world of Rare Earth Elements (or REEs). They're messy, complicated, opaque, and rich with opportunity. We talk processing, refining, production, China's dominance, how the West can build its supply chain, and individual stock names. This was terrific. Give Sustainable dude a follow and subscribe to his Substack. It is WELL worth the read. Finally, a big thanks to the following sponsors for making the podcast a reality.MitimcoThis episode is brought to you by MIT Investment Management Company, also known as MITIMCo, the investment office of MIT. Each year, MITIMCo invests in a handful of new emerging managers who it believes can earn exceptional long-term returns in support of MIT's mission. To help the emerging manager community more broadly, they created ⁠⁠⁠⁠⁠⁠emergingmanagers.org⁠⁠⁠⁠⁠⁠, a website for emerging manager stockpickers.For those looking to start a stock-picking fund or just looking to learn about how others have done it, I highly recommend the site. You'll find essays and interviews by successful emerging managers, service providers used by MIT's own managers, essays MITIMCo has written for emerging managers and more!TegusTegus has the world's largest collection of instantly available interviews on all the public and private companies you care about. Tegus actually makes primary research fun and effortless, too. Instead of weeks and months, you can learn a new industry or company in hours, and all from those that know it best.I spend nearly all my time reading Tegus calls on existing holdings and new ideas. And I know you will too. So if you're interested, head on over to ⁠⁠⁠⁠⁠⁠tegus.co/valuehive⁠⁠⁠⁠⁠⁠ for a free trial to see for yourself.TIKRTIKR is THE BEST resource for all stock market data, I use TIKR every day in my process, and I know you will too. Make sure to check them out at ⁠⁠⁠⁠⁠⁠TIKR.com/hive⁠⁠⁠⁠⁠⁠.

C dans l'air l'invité du 15 octobre 2025 avec Olivier Blanchard, professeur émérite au MIT (Boston) et à la Paris School of economics, ancien économiste en chef du FMI.Sébastien Lecornu a annoncé mardi devant l'Assemblée nationale la suspension de la réforme des retraites, symbole de la présidence Macron. Lors de sa déclaration de politique générale, il a proposé la suspension de la réforme des retraites «jusqu'à l'élection présidentielle» de 2027, qui portera sur la mesure d'âge et la durée de cotisation, comme demandé par le PS, et proposé une conférence sociale sur «les retraites et le travail». «Aucun relèvement de l'âge n'interviendra à partir de maintenant jusqu'à janvier 2028, comme l'avait précisément demandé la CFDT. En complément, la durée d'assurance sera elle aussi suspendue et restera à 170 trimestres jusqu'à janvier 2028», a indiqué le Premier ministre. Selon Sébastien Lecornu, «le coût de la suspension pour notre système de retraite est de 400 millions d'euros en 2026 et de 1,8 milliard d'euros en 2027». Il a affirmé que «cette suspension bénéficiera à terme à 3,5 millions de Français».La réforme «devra donc être compensée financièrement, y compris par des mesures d'économies» et ne pourra «pas se faire au prix d'un déficit accru», a toutefois prévenu Sébastien Lecornu, qui a souligné sa volonté de préserver «la crédibilité de notre pays» aux yeux des «prêteurs sur les marchés financiers».Olivier Blanchard, ancien économiste en chef du FMI et professeur émérite au MIT, à Boston, et à la Paris School of economics, est notre invité. Il réagira à la suspension de la réforme des retraites, et analysera les conséquences pour le déficit, alors que le FMI annonce une prévision de croissance de 0,7% pour la France en 2025. Il nous donnera aussi ses préconisations en terme de justice fiscale et de taxation des plus riches, le jour où le socialiste Olivier Faure annonce qu'il souhaite proposer la taxe Zucman sous forme d'amendement au budget.

Industry leaders from Coder, Scale AI, and Suger reveal why 95% of AI pilots fail—and share the frameworks that actually work to get agents into production.Topics Include:Panel features leaders from Coder, Scale AI, and Suger discussing agentic AI.MIT report reveals 95% of AI pilots fail to reach production.Challenges are rarely technical—they're organizational, mindset, and people-driven instead.Companies lack documented tribal knowledge needed to train agents effectively.Many organizations attempt AI where deterministic, rules-based automation would work better."Freestyle agents" concept: Some problems shouldn't be solved by agents at all.Regulated industries struggle when asking agents to handle highly differentiated, complex tasks.Common mistakes: building one universal agent or separate agents for every use case.Post-billing workflows and business-critical operations aren't ready for AI's black box.VCs pressure companies to define "AI-native"—but nobody has clear answers yet.Scale AI uses five maturity levels; Coder uses three tiers for adoption.Success metrics span operational readiness, business impact, and technology performance indicators.Production requires data governance, context, A/B testing, and robust fallback mechanisms.Even Anthropic uses agents conservatively: research tasks and log triage, no write-access.Path to 50% success requires agile frameworks, people change, and proper AI talent.Participants:Ben Potter - VP of Product, CoderRaviteja Yelamanchili - Head of Solutions Engineering, Scale AIJon Yoo - CEO, SugerAdam Ross - US, Partner Sales Sr. Leader, Amazon Web ServicesSee how Amazon Web Services gives you the freedom to migrate, innovate, and scale your software company at https://aws.amazon.com/isv/

Az nyilvánvaló, hogy mindenkinek jót tesz, ha van egy szeretett hobbija: ez kikapcsolja, feltölti, segít ellazulni a mindennapokban és kiszakadni a mókuskerékből. Van, akinek ilyen az olvasás, mások a sportban találják meg ugyanezt, de van olyan ismerősünk is, aki kovászol, süt-főz, és néhányan a takarításra esküsznek. És akkor ott vannak azok, akik horgolnak! Vagy kötnek! Vagy mindkettőt és még hímeznek is. Most meg valami elképesztő divatja lett az egésznek. Nemcsak a horgolásnak, hanem a horgolt és kötött cuccoknak is, tök jól mennek a kézzel készült termékek (sapik, táskák, felsők…). Az újrahasznosítás miatt is jó alternatíva a kötés/horgolás, a pólófonal felhasználása például elég jellemző. Hívtunk egy szakértőt is, aki velünk ellentétben tényleg tud kötni és horgolni, nem csak beszélni róla! A vendégünk Kremmer Sári, aki a Kis Kos Műhely tulajdonosa. Bővebben: 00:00:18 - Ez az adás ilyen Millenial nagymamák klubja. 00:03:00 - Nem kellett sokat várni, Nórának annyira mégsem jött be ez a gyöngyös cucc. (Amiről azóta tudjuk, hogy gyémántfestés a neve.) 00:11:06 - Életmódpercek: lehet, hogy segít a kötés leszokni a dohányzásról. Nem biztos, mi is csak tippelünk. 00:14:56 - Az interneten rendelhettek olyan csomagokat is, amikben mások megkezdett kötései vannak. Igen, jól olvastad (hallottad). 00:17:53 - Elkezdeni tuti nehéz, de miért? (Karamazov testvérek, khm...) 00:19:43 - A kötés kb. mindenre jó: jót tesz a mentális egészségnek, dopamint termel és a demencia tüneteinek megjelenését is visszaszoríthatja. Tiszta haszon, mert a végére még az is lehet, hogy sapkád, sálad, kesztyűd és pulcsid is lesz, meg mindenki másnak is a családban! 00:25:54 - Ugyanakkor a kötés egyáltalán nem olcsó hobbi... 00:31:40 - Nem árt szóba hozni a kötött és horgolt ruhadarabok mögötti munkát sem, mert lehet, hogy az üzletekben leárazott termékek után alig kapnak fizetést azok, akik elkészítették a világ másik felén. 00:36:25 - Mitől lett a horgolás és a kötés őszi-téli kuckózós lassulós hobbi? 00:39:04 - Ha most kezdenéd, akkor érdemes egy fülvédővel próbálkozni. 00:42:14 - Új dimenzió: a kötésminta-tervező influenszerek! 00:44:43 - A divatipar és a kötés világa hatnak egymásra, nézzük csak meg a Sophie's scarf-sztorit! 00:50:04 - Ezzel kapcsolatban pedig az egyik legfontosabb dolog, hogy alacsony belépési küszöbű darab. Nem bonyolult és nem kell hozzá sok drága anyag. 00:54:07 - Mi lett amúgy a bolti ruhaméretekkel? 01:02:25 - Nem lehet minden tervezőn számon kérni, de azok közül, akik kötésmintákat készítenek, egyre többen foglalkoznak azzal is, hogy szinte minden méret elérhető legyen. 01:05:50 - És mizu az ajándékozással? (Mindjárt karácsony!) 01:12:11 - Várjuk a leveleiteket, dicsekedjetek azzal is, hogy mit horgoltatok, kötöttetek, amíg hallgattátok az adást! Néhány olvasnivaló, amit érdekesnek tartunk a témában: Jó kis összefoglaló a kötés és a horgolás mentális egészségre gyakorolt pozitív hatásairól a Guardianen. De a témát már egy ideje kutatják már, mert a kötögetők/horgolók nyugodtabbak általában a hobbijuknak köszönhetően. Ha inkább videót néznél, hogy kötés/horgolás közben is elmélyülhess a témában. A kötés kb. újrahuzalozza az agyunkat, ami sok-sok szempontból jó. Az emlegetett Reddit-thread arról, hogy miért olyan hihetetlen menő a kötés és a horgolás mostanában. Illetve egy videó arról, hogy miért terjednek ennyire az ilyen tartalmak. Ha elkészítenétek az emlegetett sálat, a kötésmintákat PetiteKnit oldalán találjátok meg. Etikus forrásból pedig például a Kis Kos Műhelynél szerezhettek be fonalat és eszközöket. Kéthetente pedig Sárival is köthettek! Podcastunk kéthetente jelentkezik új adással, meghallgatható a 444 Spotify- és Apple-csatornáján is. Korábbi adásaink itt találhatók. Javaslataid, ötleteid, meglátásaid a tyukol@444.hu címre várjuk. Illusztráció: Kiss Bence/444See omnystudio.com/listener for privacy information.

Október 15-én az Ingában tartottunk élő podcastfelvételt visszatérő vendégeinkkel, Takácsy Dorka Oroszország-szakértővel, és Takács Márk katonai szakértővel, a Magyar Honvédség volt századosával, ahol Franciaországtól Kínáig beszélgettünk a nemzetközi politika aktualitásairól. A beszélgetés podcast formátumban is meghallgatható: A tartalomból:01:00: Donald Trump nem kapott Nobel-békedíjat, és a Time magazin címlapjára rakott fotójával sem elégedett. Miért fontos az oroszoknak, hogy hirtelen megcirógassák az amerikai elnök lelkét? 04:26. Tomahawk-gyorstalpaló. 09:08: A nukleáris fenyegetés vörös vonal? 10:07: A számtalan orosz vörös vonal evolúciója. 13:23: Közeleg a tél. Ha közeleg a tél, akkor menetrendszerűen növekednek az energetikai infrastruktúra elleni támadások. De most tényleg pusztítóbbak ezek, mint korábban? 16:30: Üzemanyag-problémák Oroszországban. Deja-vu percek: élelmiszerinfláció, ársapkák és a KATA eltörlése (mármint nem nálunk, hanem Oroszországban). 21:30: Kínai kémműholdak Lviv rakétázásakor, kínai drónok és alkatrészek mindkét félnél. 26:30: Oroszország szépen becsúszott Kína alá, az orosz állampolgárok erről csak a propaganda valósághajlítása után értesülnek. Kína jó, a csúnya Nyugat rossz! 33:46: Nem rossz könyvek crossover: disztópikus orosz regények az orosz-kínai egyesülés utáni pokoli életről. 35:27: Egy másik disztópia: az európai fegyverkezés göröngyös útja. 41:54: Aki magyar akar maradni, az szavazzon Orbán Viktorra, aki nem akar magyar maradni a szavazzon Ursula von der Leyenre, de akkor Ursula von der Leyen lesz. Ez most vicc vagy egy örökbecsű bölcsesség? 45:08: Gyakoribbá válhat a látványos orosz kiállás a választásokhoz közeledve? 47:42: Mi kerül ennyire nagyon-nagyon-nagyon sokba egy rakétán? Nézői kérdések:50:29: Helyes lehet az a percepció, hogy ha az ukránok elég hosszú ideig folytatják az orosz olajiparnak a támadását, akkor belátható időn belül vége lehet ennek a háborúnak? 52:57: Mennyire elképzelhető, hogy Európában kicsit kevesebb pénz jut nyugdíjra, mert rakétákra fejlesztünk? 56:35: Van még olyan ország, amelyik megközelítőleg olyan befolyással és fontossággal bír Oroszország számára, mint Kína? 59:00: Van olyan harcjármű Európában, amit futószalagon lehetne gyártani, mint a régi időkben, és oda lehetne adni az ukránoknak? A szervezettség és a szürkeállomány fontosssága. 01:03:21: Van az euroatlanti világnak lehetősége arra, hogy az orosz hátországot masszírozza olyan szándékkal, hogy vagy meggyengüljön vagy megroppanjon és ugyanerre van-e lehetőség ilyen hibrid információs műveletekkel a hadsereg a moráljának a rombolására? 01:09:12: Számszerűen mit tudunk mi a szemben álló erőkről? Hogy fejlődik az ukrán hadsereg parancsnoksága? 01:15:58: Totálisabb háború fele megyünk? A légvédelmek meggyengülése miatt már hatásosabb támadni egymás finomítóit? 01:19:05: Melyik társadalom az ütésállóbb? Az orosz vagy az ukrán? 01:24:28: Miért gondoljuk azt, hogy az oroszok az ukrajnai tapasztalatokkal a birtokukban most Európát akarják megtámadni? Mi most erre készülünk, de miért? Az oroszok nem fogják úgy félreismerni az európai társadalmakat, ahogy tették Ukrajnával. A kis zöld emberkék már az észt határon vannak. 1:31:45: Mit érdemes tudni az ukrán belpolitikáról? Sorozatajánló, ahol a vicceket és mások nyomorát is érteni fogjuk: A nép szolgája. A főszerepben: Volodimir Zelenszkij. 1:41:14: Mit gondolunk arról, hogy Európát megtámadja Oroszország, de az USA azt mondja, hogy mégsem jön segíteni?See omnystudio.com/listener for privacy information.

An avalanche of information besets us on what to eat. It comes from the news, from influencers of every ilk, from scientists, from government, and of course from the food companies. Super foods? Ultra-processed foods? How does one find a source of trust and make intelligent choices for both us as individuals and for the society as a whole. A new book helps in this quest, a book entitled Food Intelligence: the Science of How Food Both Nourishes and Harms Us. It is written by two highly credible and thoughtful people who join us today.Julia Belluz is a journalist and a contributing opinion writer for the New York Times. She reports on medicine, nutrition, and public health. She's been a Knight Science Journalism Fellow at MIT and holds a master's in science degree from the London School of Economics and Political Science. Dr. Kevin Hall trained as a physicist as best known for pioneering work on nutrition, including research he did as senior investigator and section chief at the National Institutes of Health. His work is highly regarded. He's won awards from the NIH, from the American Society of Nutrition, the Obesity Society and the American Physiological Society. Interview Transcript Thank you both very much for being with us. And not only for being with us, but writing such an interesting book. I was really eager to read it and there's a lot in there that people don't usually come across in their normal journeys through the nutrition world. So, Julia, start off if you wouldn't mind telling us what the impetus was for you and Kevin to do this book with everything else that's out there. Yes, so there's just, I think, an absolute avalanche of information as you say about nutrition and people making claims about how to optimize diet and how best to lose or manage weight. And I think what we both felt was missing from that conversation was a real examination of how do we know what we know and kind of foundational ideas in this space. You hear a lot about how to boost or speed up your metabolism, but people don't know what metabolism is anyway. You hear a lot about how you need to maximize your protein, but what is protein doing in the body and where did that idea come from? And so, we were trying to really pair back. And I think this is where Kevin's physics training was so wonderful. We were trying to look at like what are these fundamental laws and truths. Things that we know about food and nutrition and how it works in us, and what can we tell people about them. And as we kind of went through that journey it very quickly ended up in an argument about the food environment, which I know we're going to get to. We will. It's really interesting. This idea of how do we know what we know is really fascinating because when you go out there, people kind of tell us what we know. Or at least what they think what we know. But very few people go through that journey of how did we get there. And so people can decide on their own is this a credible form of knowledge that I'm being told to pursue. So Kevin, what do you mean by food intelligence? Coming from a completely different background in physics where even as we learn about the fundamental laws of physics, it's always in this historical context about how we know what we know and what were the kind of key experiments along the way. And even with that sort of background, I had almost no idea about what happened to food once we ate it inside our bodies. I only got into this field by a happenstance series of events, which is probably too long to talk about this podcast. But to get people to have an appreciation from the basic science about what is going on inside our bodies when we eat. What is food made out of? As best as we can understand at this current time, how does our body deal with. Our food and with that sort of basic knowledge about how we know what we know. How to not be fooled by these various sound bites that we'll hear from social media influencers telling you that everything that you knew about nutrition is wrong. And they've been hiding this one secret from you that's been keeping you sick for so long to basically be able to see through those kinds of claims and have a bedrock of knowledge upon which to kind of evaluate those things. That's what we mean by food intelligence. It makes sense. Now, I'm assuming that food intelligence is sort of psychological and biological at the same time, isn't it? Because that there's what you're being told and how do you process that information and make wise choices. But there's also an intelligence the body has and how to deal with the food that it's receiving. And that can get fooled too by different things that are coming at it from different types of foods and stuff. We'll get to that in a minute, but it's a very interesting concept you have, and wouldn't it be great if we could all make intelligent choices? Julia, you mentioned the food environment. How would you describe the modern food environment and how does it shape the choices we make? It's almost embarrassing to have this question coming from you because so much of our understanding and thinking about this idea came from you. So, thank you for your work. I feel like you should be answering this question. But I think one of the big aha moments I had in the book research was talking to a neuroscientist, who said the problem in and of itself isn't like the brownies and the pizza and the chips. It's the ubiquity of them. It's that they're most of what's available, along with other less nutritious ultra-processed foods. They're the most accessible. They're the cheapest. They're kind of heavily marketed. They're in our face and the stuff that we really ought to be eating more of, we all know we ought to be eating more of, the fruits and vegetables, fresh or frozen. The legumes, whole grains. They're the least available. They're the hardest to come by. They're the least accessible. They're the most expensive. And so that I think kind of sums up what it means to live in the modern food environment. The deck is stacked against most of us. The least healthy options are the ones that we're inundated by. And to kind of navigate that, you need a lot of resources, wherewithal, a lot of thought, a lot of time. And I think that's kind of where we came out thinking about it. But if anyone is interested in knowing more, they need to read your book Food Fight, because I think that's a great encapsulation of where we still are basically. Well, Julie, it's nice of you to say that. You know what you reminded me one time I was on a panel and a speaker asks the audience, how many minutes do you live from a Dunkin Donuts? And people sort of thought about it and nobody was more than about five minutes from a Dunkin Donuts. And if I think about where I live in North Carolina, a typical place to live, I'm assuming in America. And boy, within about five minutes, 10 minutes from my house, there's so many fast-food places. And then if you add to that the gas stations that have foods and the drug store that has foods. Not to mention the supermarkets. It's just a remarkable environment out there. And boy, you have to have kind of iron willpower to not stop and want that food. And then once it hits your body, then all heck breaks loose. It's a crazy, crazy environment, isn't it? Kevin, talk to us, if you will, about when this food environment collides with human biology. And what happens to normal biological processes that tell us how much we should eat, when we should stop, what we should eat, and things like that. I think that that is one of the newer pieces that we're really just getting a handle on some of the science. It's been observed for long periods of time that if you change a rat's food environment like Tony Sclafani did many, many years ago. That rats aren't trying to maintain their weight. They're not trying to do anything other than eat whatever they feel like. And, he was having a hard time getting rats to fatten up on a high fat diet. And he gave them this so-called supermarket diet or cafeteria diet composed of mainly human foods. And they gained a ton of weight. And I think that pointed to the fact that it's not that these rats lacked willpower or something like that. That they weren't making these conscious choices in the same way that we often think humans are entirely under their conscious control about what we're doing when we make our food choices. And therefore, we criticize people as having weak willpower when they're not able to choose a healthier diet in the face of the food environment. I think the newer piece that we're sort of only beginning to understand is how is it that that food environment and the foods that we eat might be changing this internal symphony of signals that's coming from our guts, from the hormones in our blood, to our brains and the understanding that of food intake. While you might have control over an individual meal and how much you eat in that individual meal is under biological control. And what are the neural systems and how do they work inside our brains in communicating with our bodies and our environment as a whole to shift the sort of balance point where body weight is being regulated. To try to better understand this really intricate interconnection or interaction between our genes, which are very different between people. And thousands of different genes contributing to determining heritability of body size in a given environment and how those genes are making us more or less susceptible to these differences in the food environment. And what's the underlying biology? I'd be lying to say if that we have that worked out. I think we're really beginning to understand that, but I hope what the book can give people is an appreciation for the complexity of those internal signals and that they exist. And that food intake isn't entirely under our control. And that we're beginning to unpack the science of how those interactions work. It's incredibly interesting. I agree with you on that. I have a slide that I bet I've shown a thousand times in talks that I think Tony Sclafani gave me decades ago that shows laboratory rats standing in front of a pile of these supermarket foods. And people would say, well, of course you're going to get overweight if that's all you eat. But animals would eat a healthy diet if access to it. But what they did was they had the pellets of the healthy rat chow sitting right in that pile. Exactly. And the animals ignore that and overeat the unhealthy food. And then you have this metabolic havoc occur. So, it seems like the biology we've all inherited works pretty well if you have foods that we've inherited from the natural environment. But when things become pretty unnatural and we have all these concoctions and chemicals that comprise the modern food environment the system really breaks down, doesn't it? Yeah. And I think that a lot of people are often swayed by the idea as well. Those foods just taste better and that might be part of it. But I think that what we've come to realize, even in our human experiments where we change people's food environments... not to the same extent that Tony Sclafani did with his rats, but for a month at a time where we ask people to not be trying to gain or lose weight. And we match certain food environments for various nutrients of concern. You know, they overeat diets that are higher in these so-called ultra-processed foods and they'd spontaneously lose weight when we remove those from the diet. And they're not saying that the foods are any more or less pleasant to eat. There's this underlying sort of the liking of foods is somewhat separate from the wanting of foods as neuroscientists are beginning to understand the different neural pathways that are involved in motivation and reward as opposed to the sort of just the hedonic liking of foods. Even the simple explanation of 'oh yeah, the rats just like the food more' that doesn't seem to be fully explaining why we have these behaviors. Why it's more complicated than a lot of people make out. Let's talk about ultra-processed foods and boy, I've got two wonderful people to talk to about that topic. Julia, let's start with your opinion on this. So tell us about ultra-processed foods and how much of the modern diet do they occupy? So ultra-processed foods. Obviously there's an academic definition and there's a lot of debate about defining this category of foods, including in the US by the Health and Human Services. But the way I think about it is like, these are foods that contain ingredients that you don't use in your home kitchen. They're typically cooked. Concocted in factories. And they now make up, I think it's like 60% of the calories that are consumed in America and in other similar high-income countries. And a lot of these foods are what researchers would also call hyper palatable. They're crossing these pairs of nutrient thresholds like carbohydrate, salt, sugar, fat. These pairs that don't typically exist in nature. So, for the reasons you were just discussing they seem to be particularly alluring to people. They're again just like absolutely ubiquitous and in these more developed contexts, like in the US and in the UK in particular. They've displaced a lot of what we would think of as more traditional food ways or ways that people were eating. So that's sort of how I think about them. You know, if you go to a supermarket these days, it's pretty hard to find a part of the supermarket that doesn't have these foods. You know, whole entire aisles of processed cereals and candies and chips and soft drinks and yogurts, frozen foods, yogurts. I mean, it's just, it's all over the place. And you know, given that if the average is 60% of calories, and there are plenty of people out there who aren't eating any of that stuff at all. For the other people who are, the number is way higher. And that, of course, is of great concern. So there have been hundreds of studies now on ultra-processed foods. It was a concept born not that long ago. And there's been an explosion of science and that's all for the good, I think, on these ultra-processed foods. And perhaps of all those studies, the one discussed most is one that you did, Kevin. And because it was exquisitely controlled and it also produced pretty striking findings. Would you describe that original study you did and what you found? Sure. So, the basic idea was one of the challenges that we have in nutrition science is accurately measuring how many calories people eat. And the best way to do that is to basically bring people into a laboratory and measure. Give them a test meal and measure how many calories they eat. Most studies of that sort last for maybe a day or two. But I always suspected that people could game the system if for a day or two, it's probably not that hard to behave the way that the researcher wants, or the subject wants to deceive the researcher. We decided that what we wanted to do was bring people into the NIH Clinical Center. Live with us for a month. And in two two-week blocks, we decided that we would present them with two different food environments essentially that both provided double the number of calories that they would require to maintain their body weight. Give them very simple instructions. Eat as much or as little as you'd like. Don't be trying to change your weight. We're not going to tell you necessarily what the study's about. We're going to measure lots of different things. And they're blinded to their weight measurements and they're wearing loose fitting scrubs and things like that, so they can't tell if their clothes are getting tighter or looser. And so, what we did is in for one two-week block, we presented people with the same number of calories, the same amount of sugar and fat and carbs and fiber. And we gave them a diet that was composed of 80% of calories coming from these ultra-processed foods. And the other case, we gave them a diet that was composed of 0% of calories from ultra-processed food and 80% of the so-called minimally processed food group. And what we then did was just measured people's leftovers essentially. And I say we, it was really the chefs and the dieticians at the clinical center who are doing all the legwork on this. But what we found was pretty striking, which was that when people were exposed to this highly ultra-processed food environment, despite being matched for these various nutrients of concern, they overate calories. Eating about 500 calories per day on average, more than the same people in the minimally processed diet condition. And they gained weight and gained body fat. And, when they were in the minimally processed diet condition, they spontaneously lost weight and lost body fat without trying in either case, right? They're just eating to the same level of hunger and fullness and overall appetite. And not reporting liking the meals any more or less in one diet versus the other. Something kind of more fundamental seemed to have been going on that we didn't fully understand at the time. What was it about these ultra-processed foods? And we were clearly getting rid of many of the things that promote their intake in the real world, which is that they're convenient, they're cheap, they're easy to obtain, they're heavily marketed. None of that was at work here. It was something really about the meals themselves that we were providing to people. And our subsequent research has been trying to figure out, okay, well what were the properties of those meals that we were giving to these folks that were composed primarily of ultra-processed foods that were driving people to consume excess calories? You know, I've presented your study a lot when I give talks. It's nice hearing it coming from you rather than me. But a couple of things that interest me here. You use people as their own controls. Each person had two weeks of one diet and two weeks of another. That's a pretty powerful way of providing experimental control. Could you say just a little bit more about that? Yeah, sure. So, when you design a study, you're trying to maximize the efficiency of the study to get the answers that you want with the least number of participants while still having good control and being able to design the study that's robust enough to detect a meaningful effect if it exists. One of the things that you do when you analyze studies like that or design studies like that, you could just randomize people to two different groups. But given how noisy and how different between people the measurement of food intake is we would've required hundreds of people in each group to detect an effect like the one that we discovered using the same person acting as their own control. We would still be doing the study 10 years later as opposed to what we were able to do in this particular case, which is completed in a year or so for that first study. And so, yeah, when you kind of design a study that way it's not always the case that you get that kind of improvement in statistical power. But for a measurement like food intake, it really is necessary to kind of do these sorts of crossover type studies where each person acts as their own control. So put the 500 calorie increment in context. Using the old fashioned numbers, 3,500 calories equals a pound. That'd be about a pound a week or a lot of pounds over a year. But of course, you don't know what would happen if people were followed chronically and all that. But still 500 calories is a whopping increase, it seems to me. It sure is. And there's no way that we would expect it to stay at that constant level for many, many weeks on end. And I think that's one of the key questions going forward is how persistent is that change. And how does something that we've known about and we discuss in our books the basic physiology of how both energy expenditure changes as people gain and lose weight, as well as how does appetite change in a given environment when they gain and lose weight? And how do those two processes eventually equate at a new sort of stable body weight in this case. Either higher or lower than when people started the program of this diet manipulation. And so, it's really hard to make those kinds of extrapolations. And that's of course, the need for further research where you have longer periods of time and you, probably have an even better control over their food environment as a result. I was surprised when I first read your study that you were able to detect a difference in percent body fat in such a short study. Did that surprise you as well? Certainly the study was not powered to detect body fat changes. In other words, we didn't know even if there were real body fat changes whether or not we would have the statistical capabilities to do that. We did use a method, DXA, which is probably one of the most precise and therefore, if we had a chance to measure it, we had the ability to detect it as opposed to other methods. There are other methods that are even more precise, but much more expensive. So, we thought that we had a chance to detect differences there. Other things that we use that we also didn't think that we necessarily would have a chance to detect were things like liver fat or something like that. Those have a much less of an ability. It's something that we're exploring now with our current study. But, again, it's all exploratory at that point. So what can you tell us about your current study? We just wrapped it up, thankfully. What we were doing was basically re-engineering two new ultra-processed diets along parameters that we think are most likely the mechanisms by which ultra-processed meals drove increased energy intake in that study. One was the non-beverage energy density. In other words, how many calories per gram of food on the plate, not counting the beverages. Something that we noticed in the first study was that ultra-processed foods, because they're essentially dried out in the processing for reasons of food safety to prevent bacterial growth and increased shelf life, they end up concentrating the foods. They're disrupting the natural food matrix. They last a lot longer, but as a result, they're a more concentrated form of calories. Despite being, by design, we chose the overall macronutrients to be the same. They weren't necessarily higher fat as we often think of as higher energy density. What we did was we designed an ultra-processed diet that was low in energy density to kind of match the minimally processed diet. And then we also varied the number of individual foods that were deemed hyper palatable according to kind of what Julia said that crossed these pairs of thresholds for fat and sugar or fat and salt or carbs and salt. What we noticed in the first study was that we presented people with more individual foods on the plate that had these hyper palatable combinations. And I wrestle with the term terminology a little bit because I don't necessarily think that they're working through the normal palatability that they necessarily like these foods anymore because again, we asked people to rate the meals and they didn't report differences. But something about those combinations, regardless of what you call them, seemed to be driving that in our exploratory analysis of the first study. We designed a diet that was high in energy density, but low in hyper palatable foods, similar to the minimally processed. And then their fourth diet is with basically low in energy density and hyper palatable foods. And so, we presented some preliminary results last year and what we were able to show is that when we reduced both energy density and the number of hyper palatable foods, but still had 80% of calories from ultra-processed foods, that people more or less ate the same number of calories now as they did when they were the same people were exposed to the minimally processed diet. In fact they lost weight, to a similar extent as the minimally processed diet. And that suggests to me that we can really understand mechanisms at least when it comes to calorie intake in these foods. And that might give regulators, policy makers, the sort of information that they need in order to target which ultra-processed foods and what context are they really problematic. It might give manufacturers if they have the desire to kind of reformulate these foods to understand which ones are more or less likely to cause over consumption. So, who knows? We'll see how people respond to that and we'll see what the final results are with the entire study group that, like I said, just finished, weeks ago. I respond very positively to the idea of the study. The fact that if people assume ultra-processed foods are bad actors, then trying to find out what it is about them that's making the bad actors becomes really important. And you're exactly right, there's a lot of pressure on the food companies now. Some coming from public opinion, some coming from parts of the political world. Some from the scientific world. And my guess is that litigation is going to become a real actor here too. And the question is, what do you want the food industry to do differently? And your study can really help inform that question. So incredibly valuable research. I can't wait to see the final study, and I'm really delighted that you did that. Let's turn our attention for a minute to food marketing. Julia, where does food marketing fit in all this? Julia - What I was very surprised to find while we were researching the book was this deep, long history of calls against marketing junk food in particular to kids. I think from like the 1950s, you have pediatrician groups and other public health professionals saying, stop this. And anyone who has spent any time around small children knows that it works. We covered just like a little, it was from an advocacy group in the UK that exposed aid adolescents to something called Triple Dip Chicken. And then asked them later, pick off of this menu, I think it was like 50 items, which food you want to order. And they all chose Triple Dip chicken, which is, as the name suggests, wasn't the healthiest thing to choose on the menu. I think we know obviously that it works. Companies invest a huge amount of money in marketing. It works even in ways like these subliminal ways that you can't fully appreciate to guide our food choices. Kevin raised something really interesting was that in his studies it was the foods. So, it's a tricky one because it's the food environment, but it's also the properties of the foods themselves beyond just the marketing. Kevin, how do you think about that piece? I'm curious like. Kevin - I think that even if our first study and our second study had turned out there's no real difference between these artificial environments that we've put together where highly ultra-processed diets lead to excess calorie intake. If that doesn't happen, if it was just the same, it wouldn't rule out the fact that because these foods are so heavily marketed, because they're so ubiquitous. They're cheap and convenient. And you know, they're engineered for many people to incorporate into their day-to-day life that could still promote over consumption of calories. We just remove those aspects in our very artificial food environment. But of course, the real food environment, we're bombarded by these advertisements and the ubiquity of the food in every place that you sort of turn. And how they've displaced healthy alternatives, which is another mechanism by which they could cause harm, right? It doesn't even have to be the foods themselves that are harmful. What do they displace? Right? We only have a certain amount the marketers called stomach share, right? And so, your harm might not be necessarily the foods that you're eating, but the foods that they displaced. So even if our experimental studies about the ultra-processed meals themselves didn't show excess calorie intake, which they clearly did, there's still all these other mechanisms to explore about how they might play a part in the real world. You know, the food industry will say that they're agnostic about what foods they sell. They just respond to demand. That seems utter nonsense to me because people don't overconsume healthy foods, but they do overconsume the unhealthy ones. And you've shown that to be the case. So, it seems to me that idea that they can just switch from this portfolio of highly processed foods to more healthy foods just doesn't work out for them financially. Do you think that's right? I honestly don't have that same sort of knee jerk reaction. Or at least I perceive it as a knee jerk reaction, kind of attributing malice in some sense to the food industry. I think that they'd be equally happy if they could get you to buy a lot and have the same sort of profit margins, a lot of a group of foods that was just as just as cheap to produce and they could market. I think that you could kind of turn the levers in a way that that would be beneficial. I mean, setting aside for example, that diet soda beverages are probably from every randomized control trial that we've seen, they don't lead to the same amount of weight gain as the sugar sweetened alternatives. They're just as profitable to the beverage manufacturers. They sell just as many of them. Now they might have other deleterious consequences, but I don't think that it's necessarily the case that food manufacturers have to have these deleterious or unhealthy foods as their sole means of attaining profit. Thanks for that. So, Julia, back to you. You and Kevin point out in your book some of the biggest myths about nutrition. What would you say some of them are? I think one big, fundamental, overarching myth is this idea that the problem is in us. That this rise of diet related diseases, this explosion that we've seen is either because of a lack of willpower. Which you have some very elegant research on this that we cite in the book showing willpower did not collapse in the last 30, 40 years of this epidemic of diet related disease. But it's even broader than that. It's a slow metabolism. It's our genes. Like we put the problem on ourselves, and we don't look at the way that the environment has changed enough. And I think as individuals we don't do that. And so much of the messaging is about what you Kevin, or you Kelly, or you Julia, could be doing better. you know, do resistance training. Like that's the big thing, like if you open any social media feed, it's like, do more resistance training, eat more protein, cut out the ultra-processed foods. What about the food environment? What about the leaders that should be held accountable for helping to perpetuate these toxic food environments? I think that that's this kind of overarching, this pegging it and also the rise of personalized nutrition. This like pegging it to individual biology instead of for whatever the claim is, instead of thinking about how did environments and don't want to have as part of our lives. So that's kind of a big overarching thing that I think about. It makes sense. So, let's end on a positive note. There's a lot of reason to be concerned about the modern food environment. Do you see a helpful way forward and what might be done about this? Julia, let's stay with you. What do you think? I think so. We spent a lot of time researching history for this book. And a lot of things that seem impossible are suddenly possible when you have enough public demand and enough political will and pressure. There are so many instances and even in the history of food. We spend time with this character Harvey Wiley, who around the turn of the century, his research was one of the reasons we have something like the FDA protecting the food supply. That gives me a lot of hope. And we are in this moment where a lot of awareness is being raised about the toxic food environment and all these negative attributes of food that people are surrounded by. I think with enough organization and enough pressure, we can see change. And we can see this kind of flip in the food environment that I think we all want to see where healthier foods become more accessible, available, affordable, and the rest of it. Sounds good. Kevin, what are your thoughts? Yes, I just extend that to saying that for the first time in history, we sort of know what the population of the planet is going to be that we have to feed in the future. We're not under this sort of Malthusian threat of not being able to know where the population growth is going to go. We know it's going to be roughly 10 billion people within the next century. And we know we've got to change the way that we produce and grow food for the planet as well as for the health of people. We know we've got to make changes anyway. And we're starting from a position where per capita, we're producing more protein and calories than any other time in human history, and we're wasting more food. We actually know we're in a position of strength. We don't have to worry so acutely that we won't be able to provide enough food for everybody. It's what kind of food are we going to produce? How are we going to produce it in the way that's sustainable for both people and the planet? We have to tackle that anyway. And for the folks who had experienced the obesity epidemic or finally have drugs to help them and other kinds of interventions to help them. That absolve them from this idea that it's just a matter of weak willpower if we finally have some pharmaceutical interventions that are useful. So, I do see a path forward. Whether or not we take that is another question. Bios Dr. Kevin Hall is the section chief of Integrative Physiology Section in the Laboratory of Biological Modeling at the NIH National Institute of Diabetes and Digestive and Kidney Diseases. Kevin's laboratory investigates the integrative physiology of macronutrient metabolism, body composition, energy expenditure, and control of food intake. His main goal is to better understand how the food environment affects what we eat and how what we eat affects our physiology. He performs clinical research studies as well as developing mathematical models and computer simulations to better understand physiology, integrate data, and make predictions. In recent years, he has conducted randomized clinical trials to study how diets high in ultra-processed food may cause obesity and other chronic diseases. He holds a Ph.D. from McGill University. Julia Belluz is a Paris-based journalist and a contributing opinion writer to the New York Times, she has reported extensively on medicine, nutrition, and global public health from Canada, the US, and Europe. Previously, Julia was Vox's senior health correspondent in Washington, DC, a Knight Science Journalism fellow at the Massachusetts Institute of Technology in Cambridge, and she worked as a reporter in Toronto and London. Her writing has appeared in a range of international publications, including the BMJ, the Chicago Tribune, the Economist, the Globe and Mail, Maclean's, the New York Times, ProPublica, and the Times of London. Her work has also had an impact, helping improve policies on maternal health and mental healthcare for first responders at the hospital- and state-level, as well as inspiring everything from scientific studies to an opera. Julia has been honored with numerous journalism awards, including the 2016 Balles Prize in Critical Thinking, the 2017 American Society of Nutrition Journalism Award, and three Canadian National Magazine Awards (in 2007 and 2013). In 2019, she was a National Academies of Sciences, Engineering, and Medicine Communications Award finalist. She contributed chapters on public health journalism in the Tactical Guide to Science Journalism, To Save Humanity: What Matters Most for a Healthy Future, and was a commissioner for the Global Commission on Evidence to Address Societal Challenges.

Funktionsmodus frisst Lebendigkeit: Wenn Alltag und Beziehungen nur noch im Überlebensmodus ablaufen, gerät Empathie ins Abseits, der eigene Körper wirkt fremd. Sandra Quedenbaum – Coachin für Hochsensibilität und Trauma – zeigt, warum Leistung ohne Pause ins Leere führt und wie ein innerer Notausstieg den Kreislauf aus Anspannung, Dissoziation und Erschöpfung aufbricht. Wer echte Nähe sucht, findet im bewussten Kontakt die Kraftquelle für Regeneration. Du erfährst... ...wie du den Funktionsmodus erkennst und ihm entkommst. ...welche fünf Schritte zu mehr Lebendigkeit und Energie führen. ...warum bewusste Momente und soziale Kontakte Kraftquellen sind. __________________________ ||||| PERSONEN |||||

Dr. Mark McClellan has served as a Member of the President's Council of Economic Advisors, Administrator of the Centers for Medicare & Medicaid Services (CMS), and Commissioner of the U.S. Food and Drug Administration (FDA). But his experiences before, and accomplishments following these leadership roles at the highest levels of government health policy are equally important to his perspective on the healthcare ecosystem – especially during a time of rapid policy change.Dr. McClellan always intended on pursuing a medical degree and entered a joint Harvard-MIT program that took him in a slightly different direction. He ended up studying economics and the rising cost of healthcare at MIT. He ultimately earned a medical degree from the Harvard-MIT Division of Health Sciences and Technology, a Ph.D. in economics from MIT, and a master's in public administration from Harvard's Kennedy School.Dr. McClellan began his career at the Treasury Department in the Clinton Administration, and returned to public service under the George W. Bush Administration where he led the FDA and CMS. Today, Dr. McClellan is the Robert J. Margolis, M.D., Professor of Business, Medicine and Policy at Duke University and the founding Director of the Duke-Margolis Institute for Health Policy. His work centers on improving health care through policy and research, with a focus on payment reforms, quality, value, and biomedical innovation.With his expertise in medicine, economics and public policy, Dr. McClellan talked to Keith Figlioli in this episode of Healthcare is Hard to share his perspective on adapting to rapid change in the current healthcare landscape. Topics they discussed include:Misalignment of innovation and outcomes. While advancements in digital health are coming to market faster than ever before, Dr. McClellan says there's still a lack of technology truly centered on keeping patients healthy. He says traditional payment methods make it hard to support this type of innovation. For example, advancements in AI are helping physicians gather information for prior authorization requests, and ambient scribing saves time with note taking and administration. But these technologies essentially help providers see more fee-for-service patients or bill for more profitable services. He argues that more outcome-oriented payments are needed to advance technology-embedded care models. The evolution of value-based care. After Congress passed the Medicare Modernization Act in 2003 to establish Medicare Advantage, Dr. McClellan became administrator of CMS at the President's request to lead its implementation. With unique insight from leading some of the earliest VBC programs, he shared his thoughts on the speed of adoption and why it hasn't happened faster. He discussed how early MA models needed to be based on existing fee-for-service infrastructure, his surprise that not much has changed, and his optimism that it's finally starting to.Mobilizing private capital for public health. Private investment will be essential to support the significant changes required to improve healthcare – especially with uncertainties around future levels of government funding. Dr. McClellan explained how the Duke-Margolis Capital Impact Council (CIC) was launched to guide and improve the role of private investment in healthcare. He described how members of the council are developing and sharing practices for investors and their portfolio companies to track health value return on investment alongside financial ROI.To hear Dr. McClellan and Keith discuss these topics and more, listen to this episode of Healthcare is Hard: A Podcast for Insiders.

Als Gründer des Miniatur Wunderlandes hat Frederik Braun eine große kleine Welt in der Hamburger Speicherstadt erschaffen - zusammen mit seinem Zwillingsbruder. Mit dem führte er zuvor auch schon acht Jahre lang eine Diskothek.

Vorurteile über die Franken gibt es reichlich, etwa die oft zitierte Wortkargheit. Damit räumt die Linguistin und Sprachhistorikerin Christine Ganslmayer jetzt aber auf - in ihrem Buch "Fränkisch. Des is fei schäi" (Duden Verlag). Mit uns spricht sie über innere Mehrsprachigkeit durch Dialektwissen, über die jiddischen Einflüsse in den fränkischen Dialekten und über das berühmte Schäuferla.

Vom typischen D2C-Start auf Amazon und eigenem Onlineshop hat sich Glow25 zu einer erfolgreichen Marke entwickelt und prägt bereits nach wenigen Jahren den deutschen Markt für Kollagen-Supplements. Mit nur vier Kernprodukten schafft die Marke eine außergewöhnliche Kundenbindung: eine Facebook-Community von 66.000 Glowies, fast 70 % Wiederkäufer:innen und eine 18-prozentige Subscription-Rate. Karo spricht mit CEO Steven Mattwig über die Strategien hinter diesem Erfolg. Welche Rolle spielen Community und Stars wie Bill Kaulitz in der Marketingstrategie und im Vertrauensaufbau der Kund:innen? Wie nutzt Glow25 AI und Ads-Testing, um Wachstum zu skalieren? Und welche Strategien treiben die Expansion in Europa und darüber hinaus voran? Das Gespräch im Überblick: (2:28) Die Entstehung von Glow25 (10:41) Produktportfolio & Zielgruppe: Was bewirkt Kollagen und wer nutzt es? (9:17) Marketing & Vertrieb: Sichtbarkeit, Kanäle und Kundenansprache (18:04) Die Community der Glowies (24:34) Preisstrategien, Abo-Modelle und Customer Lifetime Value (38:58) Influencer-Kooperationen: Von Mikro-Influencer:innen bis zu den Kaulitz-Hills (42:27) Expansion & Zukunftspläne: Neue Märkte, Vertriebskanäle und AI Podcast-Host – Karo Junker de Neui: https://www.linkedin.com/in/karojunker https://etribes.de/ Newsletter: https://www.kassenzone.de/newsletter/ Community: https://kassenzone.de/discord Disclaimer: https://www.kassenzone.de/disclaimer/ Youtube: https://www.youtube.com/c/KassenzoneDe/ Blog: https://www.kassenzone.de/ Kassenzone wird vermarktet von Podstars by OMR. Du möchtest in Kassenzone werben? Dann https://podstars.de/kontakt/?utm_source=podcast&utm_campaign=shownotes_kassenzone

Auslosen oder doch freiwillig melden? Die Frage, wie genau der neue Wehrdienst funktionieren soll, spaltet gerade die Bundesregierung. Klar ist – da sind sich Union und SPD einig – Deutschland braucht mehr Soldat:innen, nicht zuletzt wegen der wachsenden Bedrohung durch Russland. Wie das gelingen soll, erzählt in dieser 11KM-Folge der NDR-Verteidigungsexperte Kai Küstner. Mit ihm klären wir, wer bald Post von der Bundeswehr bekommen könnte und worum es beim neuen Wehrdienst genau geht. Redaktionsschluss für diese Folge war der 15. Oktober 2025 um 18 Uhr. Hier geht's zu unserem Podcast-Tipp “Streitkräfte und Strategien” mit Kai Küstner: https://1.ard.de/Streitkraefte_und_Strategien Alle aktuellen Entwicklungen in der Wehrdienst-Diskussion findet ihr auf Tagesschau.de: https://www.tagesschau.de/thema/wehrpflicht In dieser früheren 11KM-Folge klären wir, wie Wehrdienst in Schweden funktioniert und ob das ein Vorbild für Deutschland sein könnte: https://1.ard.de/11KM_Wehrdienst_Schweden Diese und viele weitere Folgen von 11KM findet ihr überall da, wo es Podcasts gibt, auch hier in der ARD Audiothek: https://www.ardaudiothek.de/sendung/11km-der-tagesschau-podcast/12200383/ An dieser Folge waren beteiligt: Folgenautorin: Charlotte Horn Mitarbeit: Sebastian Schwarzenböck Host: Elena Kuch Produktion: Jan Stahlmann, Konrad Winkler, Marie-Noelle Svihla und Hanna Brünjes Planung: Caspar von Au und Hardy Funk Distribution: Kerstin Ammermann Redaktionsleitung: Fumiko Lipp und Nicole Dienemann 11KM: der tagesschau-Podcast wird produziert von BR24 und NDR Info. Die redaktionelle Verantwortung für diese Episode liegt beim BR.

How does food DNA impact the human body? In what ways do ecological communities in the gut change and adapt to individual people over time? Join us in this episode as Dr. Sean Gibbons discusses a breakthrough method that analyzes food-derived DNA in fecal metagenomes – and what this means for human health… Dr. Gibbon leads the Gibbons Lab at the Institute for Systems Biology, where he works to better understand and improve how the gut microbiome affects our health, utilizing a range of approaches, from hands-on experimentation to computer tools. His goal is to help create more personalized medical treatments. How? By accurately tracking dietary intake from gut microbiome samples and ultimately fostering better nutrition research and overall precision health. Click play to find out: How the human microbiome influences our responses to diet, drugs, and more. What food DNA is, and where this idea comes from. The strongest driver of microbiome composition. How accurate dietary data is collected. Dr. Sean Gibbons earned his Ph.D. in Biophysical Sciences from the University of Chicago in 2015. He then completed postdoctoral training in Eric Alm's lab in the Department of Biological Engineering at MIT (2015–2018), where he developed techniques to measure how the human gut microbiome changes and evolves in individual people. He is now a full-time microbiome researcher and an Associate Professor at the Institute for Systems Biology. Want to follow along with Dr. Gibbons's work with Gibbons Lab? Click here now! Episode also available on Apple Podcasts: http://apple.co/30PvU9C

In 2009, the U.S. Department of Defense issued a bizarre challenge: find 10 red weather balloons hidden across theUnited States and do it faster than anyone else. What followed was a test not just of internet savvy, but of leadership in the digital age. In this episode, we dive into the winning strategy from MIT, uncover why most teams failed, and extract powerful lessons about networks, incentives, and what it really means to lead when scale and speed matter most.—Learn To Lead is brought to you by Abilitie, a leading provider of experiential learning. Abilitie's simulations and leadership programs have inspired over 100,000 professionals in more than 50 countries. To learn more about Abilitie and about our host Matthew Confer, visit the links below:Abilitie Leadership Development - https://www.abilitie.comThe Learn To Lead Podcast - https://www.abilitie.com/learn-to-lead-podcast/Host Matthew Confer:LinkedIn - https://www.linkedin.com/in/matthewconfer/Matthew's TEDx Talk on Decision Making - https://www.ted.com/talks/matthew_confer_before_you_decide_3_steps_to_better_decision_makingMake sure you subscribe to our show to ensure you get our next episode when it is released.

Im ersten Prozess gegen Signa-Gründer René Benko hat es den ersten Schuldspruch gegen den gefallenen Immobilientycoon gegeben. Wie es zu diesem Urteil gekommen ist und was dem einstigen Politliebling noch alles droht, darüber sprechen wir mit Renate Graber und Jakob Pflügel aus der Wirtschaftsredaktion des STANDARD. **Hat Ihnen dieser Podcast gefallen?** Mit einem STANDARD-Abonnement können Sie unsere Arbeit unterstützen und mithelfen, Journalismus mit Haltung auch in Zukunft sicherzustellen. Alle Infos und Angebote gibt es hier: [abo.derstandard.at](https://abo.derstandard.at/?ref=Podcast&utm_source=derstandard&utm_medium=podcast&utm_campaign=podcast&utm_content=podcast)

On this episode of the Woodard Report podcast, Joe speaks with Jeff about the future of AI in accounting and how predictive models can transform bookkeeping accuracy. Jeff shares how his company, Digits, leverages AI not to replace accountants but to streamline workflows, reduce errors, and give professionals more time for higher-value work. They also explore the difference between generative and predictive AI, the role of accountants in reviewing outputs, and why firms must adapt quickly or risk being outpaced by competitors. About Jeff Seibert Jeff Seibert is the co-founder and CEO of Digits, where he's building the world's first AI-powered accounting platform for startups and small businesses. Jeff is also a frequent presenter on both entrepreneurial and technical topics and has lectured at Stanford, Harvard, MIT, and Tufts, as well as keynoted Scaling New Heights, Twitter Flight, AppsWorld, AnDevCon, EclipseCon, and others. Learn more about Jeff at: JeffSeibert.com Twitter LinkedIn Thank you to our show sponsor, Canopy! Unclunk your firm with Canopy, the fully integrated practice management that helps accountants build the firm they always wanted. The suite includes client and document management, workflow, time and billing, engagements and proposals, and more. Check out getcanopy.com. Learn more about the show and our sponsors at Woodard.com/podcast

Strategisches Cross- und Upselling entfaltet Kraft erst dort, wo Beziehungen wachsen – nicht Verträge. Gero Decker beleuchtet, warum echte Umsatzsteigerung in der klugen Entwicklung von Accounts und den individuellen Herausforderungen großer Kunden liegt. Es geht um den Wert gemeinsamer Landkarten, kluge Pricing-Logik und die Kunst, Bedürfnisse früh zu erkennen. Erfolg entsteht nicht aus Taktik, sondern aus wirklicher Nähe zum Kunden. Wer Wachstum führen will, denkt Customer Success als gelebte Verantwortung – nicht nur als Rolle. Du erfährst... In dieser Episode erfährst du… …wie du mit Cross- und Upselling deine Kundenbeziehungen vertiefst. …warum die ersten 30 Tage entscheidend für den Erfolg im SaaS-Bereich sind. …welche Rolle Customer Success bei der langfristigen Kundenbindung spielt. __________________________ ||||| PERSONEN |||||

- Give me (M)5: MacBook Pro, iPad Pro und Vision Pro mit M5 vorgestellt - Und Cut! Apple stellt seine App Clips ein - Das Kreuz mit dem Plus: Droht ein Apple-TV-Namenschaos? - Mal sehen: Vision-Pro-Entwicklung angeblich zugunsten von Smart Glasses eingestellt - Scharfe Kamera im scharfen Schirm: Neues Pro Display XDR in macOS 26 entdeckt - Umfrage der Woche - Zuschriften unserer Hörer === Anzeige / Sponsorenhinweis === Sichere dir 4 EXTRA-Monate auf einen 2-Jahresplan über https://nordvpn.com/apfelfunk Teste NordVPN jetzt risikofrei mit der 30 Tage Geld-Zurück-Garantie. === Anzeige / Sponsorenhinweis Ende === Links zur Sendung: - Mac & i: MacBook Pro und iPad Pro 2025 sagen Hallo - https://www.heise.de/news/Mit-Apple-M5-MacBook-Pro-und-iPad-Pro-2025-sagen-Hallo-10767488.html - Apple Newsroom: Apple stellt den M5 vor, den nächsten grossen Sprung bei KI Performance für Apple Chips - https://www.apple.com/de/newsroom/2025/10/apple-unleashes-m5-the-next-big-leap-in-ai-performance-for-apple-silicon/ - Apfelfunk News: Apple stellt Video-App Clips ein und entfernt sie aus dem App Store - https://apfelfunk.com/apple-stellt-video-app-clips-ein-und-entfernt-sie-aus-dem-app-store/ - Mac & i: Apple TV+ lässt das Plus weg - https://www.heise.de/news/Buntes-Rebranding-Apple-TV-laesst-das-Plus-weg-10757270.html - Apfelfunk m5: Apple pausiert angeblich gesamte Vision Pro-Entwicklung zugunsten von Smart Glasses - https://apfelfunk.com/apple-pausiert-angeblich-gesamte-vision-pro-entwicklung-zugunsten-von-smart-glasses/ - Mac & i: Hinweis auf Apples neuen Profi-Bildschirm - https://www.heise.de/news/Mit-wichtiger-Hardware-Aenderung-Hinweis-auf-Apples-neuen-Profi-Bildschirm-10760756.html Wir danken unseren Unterstützern! Du möchtest den Podcast auch supporten? Hier gibt es mehr Infos: https://steadyhq.com/de/apfelfunk/about Kapitelmarken: (00:00:00) Begrüßung (00:14:00) Werbung (00:17:13) Begrüßung (00:18:19) Themen (00:19:18) Give me (M)5: MacBook Pro, iPad Pro und Vision Pro mit M5 vorgestellt (01:04:45) Und Cut! Apple stellt seine App Clips ein (01:10:16) Das Kreuz mit dem Plus: Droht ein Apple-TV-Namenschaos? (01:16:55) Mal sehen: Vision-Pro-Entwicklung angeblich zugunsten von Smart Glasses eingestellt (01:22:37) Scharfe Kamera im scharfen Schirm: Neues Pro Display XDR in macOS 26 entdeckt (01:25:29) Umfrage der Woche (01:29:28) Zuschriften unserer Hörer

These days, it feels like we're bombarded with information from every direction, and figuring out what's true can be overwhelming. Yael sits down with Alex Edmans, author of May Contain Lies, for a fascinating conversation about how misinformation shapes the way we see the world. They talk about why even fact-checking has its limits and how common biases, such as wanting to confirm what we already believe or seeing things in black and white, can cloud our judgment. Using everyday examples, from the Atkins diet to debates about breastfeeding, Alex shows how data can be bent to tell almost any story. We invite you to stay curious but skeptical, with practical strategies for navigating opposing views and creating more thoughtful, respectful conversations.Listen to POTC ad-free for just $5 a month by becoming a Mega Supporter on Patreon! Or, support the podcast with a one-time donation at Buy Me A Coffee!Listen and Learn:Why simply “checking the facts” isn't enough and how even accurate data can mislead when context, updates, or evolving evidence are ignoredHow confirmation bias subtly shapes our judgments, even among experts and leadersWhy we're drawn to simple, black-and-white explanations and how applying scientific thinking and questioning our own biases helps us see nuance, challenge popular myths, and make more informed decisionsThe danger of oversimplified advice and the lasting impact of misinformation, and why real progress and understanding come from embracing complexity and questioning easy answersBeing “data-driven” isn't enough, and true understanding comes from distinguishing data from evidenceHow reframing conflict through curiosity and focusing on shared goals, rather than opposition, can transform disagreements into opportunities for collaboration, deeper understanding, and personal growthManaging disagreements by calming their initial reactions, focusing on shared goals, and giving others the benefit of the doubt, turning conflict into an opportunity for understanding and growthResources: May Contain Lies: How Stories, Statistics, and Studies Exploit Our Biases--And What We Can Do about It https://bookshop.org/a/30734/9780520405851 Alex's Website: https://alexedmans.com/ Connect with Alex on Social Media: https://www.instagram.com/aedmanshttps://www.linkedin.com/in/aedmans/https://twitter.com/aedmans About Alex Edmans: Alex Edmans is a Professor of Finance at London Business School, where his ability to translate complex ideas has earned him 28 teaching awards and the title of Poets & Quants Professor of the Year in 2021. His journey has taken him from Oxford to Wall Street (Morgan Stanley), then to MIT as a Fulbright Scholar for his PhD, followed by tenure at Wharton before joining LBS.Alex moves fluidly between academia and the real world—he's testified in Parliament, spoken at Davos, and somehow convinced 3 million people to watch his TED talks. His latest book, May Contain Lies: How Stories, Statistics, and Studies Exploit Our Biases—And What We Can Do About It, arrives at exactly the right moment for our post-truth era, where everyone's an expert and every statistic can be bent to tell the story you want to hear.Related Episodes:245. Family Firm with Emily Oster311. Nobody's Fool with Daniel Simons and Christopher Chabris382. The Anxious Generations? The Conversation We Should be Having About Kids, Technology, and Mental HealthSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In dieser Folge ist KIKA-Moderatorin Clarissa Corrêa da Silva zu Gast ("Wissen macht Ah") . Die 35-Jährige spricht im Podcast über ihre komplexe deutsch-israelisch-brasilianische Patchworkfamilie. Wie sie den Umzug nach São Paulo als Teenager verkraftete, welche Rolle Rassismus in ihrem Leben spielte – und wie sie beim Fernsehen landete. Wir sprechen über ihr Buch "Mein wunderbares ich", das erste Kindersachbuch über Epigenetik, und der damit verbundenen Wissens- aber auch Familienrecherche. Über "schicke Deutsche" in Brasilien, ihre Annäherung zu ihrem leiblichen israelischen Vater, Kulturschock in Baden-Württemberg – und was sie bei ihrem ersten Fernsehjob beim Thüringer Karneval erlebte. Buch: "Mein wunderbares ich - Was mich ausmacht und welche Rolle die Gene dabei spielen: Das erste Kindersachbuch über Epigenetik von „Wissen macht Ah!“- Moderatorin Clari" https://www.instagram.com/clarissa.correa.da.silva/ (02:35) Passkontrolle (08:30) Klischee-Check (21:45) Dorf Berlin: "Brasilien war immer dabei, Israel hat keine Rolle gespielt" (41:40) Mit 14 nach Sāo Paulo: Horror, Hohe Mauern & Reiche Erfahrung (55:05) Schicksalsschlag, Studium in Deu & Kulturschock in Stuttgart (1:06:00) Kinderkanal: Erst hinter, dann vor der Kamera (1:16:45) Buch "Mein wunderbares ich" & Annäherung an leiblichen Vater SUPPORT: Halbe Katoffl unterstützen: https://halbekatoffl.de/unterstuetzen/ Paypal: frank@halbekatoffl.de Steady: https://steady.page/de/halbekatoffl/about Überweisung/ Dauerauftrag: Schreib an frank@halbekatoffl.de | Stichwort: KONTO PODCAST WORKSHOP & BERATUNG https://halbekatoffl.de/workshops/ KONTAKT: frank@halbekatoffl.de

About the Guest:Jose Garcia is the President of Alberici Constructors, one of the top construction firms in the U.S. He's a West Point, Stanford, and MIT graduate, a passionate advocate for mentorship, and the founder of Strong to Serve, a nonprofit supporting orphans in Nicaragua.His story is one of bold choices, deep character, and a relentless pursuit of excellence.What You Will Learn:Why adversity can be the foundation for leadershipHow feedback, when given with care, unlocks growthWhy self-awareness is the #1 predictor of leadership successHow Dale Carnegie's principles shaped a servant leaderThe power of mindset in building culture and thriving teamsJoin us for this inspiring conversation about grit, growth, and the kind of leadership that leaves a legacy. Whether you're leading a team, mentoring others, or climbing your own mountain, this episode will help you take command—one step, one breath at a time. Please rate and review this Episode!We'd love to hear from you! Leaving a review helps us ensure we deliver content that resonates with you. Your feedback can inspire others to join our Take Command: A Dale Carnegie Podcast community & benefit from the leadership insights we share.

In this week's episode, we are speaking with Deborah Blum, environmental journalist, Pulitzer-prize winning science writer and science columnist. Let me explain why we have asked Deborah to join us. In 1962, American marine biologist, science writer, and conservationist Rachel Carson writes a pivotal book in our history, titled Silent Spring, which skillfully lays out the very real life scenario of how and where poisonous chemicals and controls, like DDT, were created and distributed by the US government in hand with major chemical companies and were used in agricultural fields, orchards, and private homeowners.What consumers didn't know at the time was that chemicals like DDT were doing immeasurable and great harm to animals, ecosystems, and humans. We have asked Deborah Blum to speak with us about Rachel Carson because of Blum's extensive qualifications as a science writer, and for the fact that she only just recently retired as the Director of the Knight Science Journalism program at MIT, and has specialised in toxicology for the last 15 years, writing about poisons and pesticides in our everyday lives.Time Stamps:Intro: 00:15Interview: 9:40TA: 55:50Show Notes:⁠https://deborahblum.com/⁠PBS with Blum featured⁠https://www.youtube.com/watch?v=SeJNRaE11A0⁠A short film on Rachel Carson⁠https://www.youtube.com/watch?v=ezVEzCmiXM4⁠

What if everything you thought you knew about startup success was wrong? In today's episode of It Gets Late Early, I'm breaking down the myth that young, hoodie-wearing entrepreneurs are the key to successful startups. Spoiler: the data proves otherwise. According to MIT research, the average age of a high-growth startup founder is 42 — not 21. The top 1% of founders are even older, typically around 45 years old. Yet, venture capitalists continue to invest in young, inexperienced founders, ignoring the seasoned leaders with decades of experience.I also tackle the growing age discrimination in tech, where older workers are pushed out despite having the experience and connections that drive success. Companies that embrace diverse ages and experiences in their teams are the ones that succeed. Let's flip the script on startup success. It's time to stop assuming that youth equals innovation. It's never too late to go after your dreams, and age is an asset, not a liability.“So just why is it that older workers tend to be more successful? Two words: life experience.” ~ Maureen Wiley CloughIn This Episode:-Research from MIT: the truth about successful startup founders-The age bias in venture capital and tech hiring-Why older founders have an advantage over younger ones-The challenge to venture capitalists: stop funding failure-Encouraging older tech workers: your experience mattersAnd much more!Resources:-Free Guide to LinkedIn Job Hunting for the 40+ Crew - https://www.itgetslateearly.com/job-guide-EEOC Special Report - https://www.eeoc.gov/special-report/high-tech-low-inclusion-diversity-high-tech-workforce-and-sector-2014-2022-MIT Research on Age and High-Growth Entrepreneurship - https://mitsloan.mit.edu/shared/ods/documents?PublicationDocumentID=6212#:~:text=Our%20primary%20finding%20is%20that,growth%20new%20ventures%20is%2045.0.-Ageism in Tech Hiring - https://www.linkedin.com/posts/maureenwclough_tech-ageism-hiring-activity-7369769952683171841-u7zS?utm_source=social_share_send&utm_medium=member_desktop_web&rcm=ACoAAACPAV4BMEaPyyLI0T1Hayp_eLtXH5AO5-4-iPhone unveiling with Steve Jobs - https://www.youtube.com/watch?v=x7qPAY9JqE4-Workplace Age Discrimination Cases Grow Nationwide - https://gbsbenefitsgroup.com/workplace-age-discrimination-cases-grow-nationwide/#:~:text=The%20Equal%20Employment%20Opportunity%20Commission%20(EEOC)%20has,Act%20(ADEA)%20as%20in%20fiscal%20year%202022-Late-Career Job Losses Are Blurring What Retirement Looks Like in America -

Jim Collins, Termeer Professor at MIT, unveils his AI-powered project that has discovered several new antibiotics, effective against resistant strains and often employing entirely new mechanisms of action. He details how their refined multi-step AI process, even with small datasets and modest compute, can efficiently screen vast chemical spaces to identify promising drug candidates. This breakthrough offers a realistic and affordable path to tackling the staggering antibiotic resistance crisis, which currently claims over a million lives annually. Collins argues this practical application of AI represents a transformative win for humanity, often overlooked amidst the focus on AGI. Sponsors: AssemblyAI: AssemblyAI is the speech-to-text API for building reliable Voice AI apps, offering high accuracy, low latency, and scalable infrastructure. Start building today with $50 in free credits at https://assemblyai.com/cognitive Claude: Claude is the AI collaborator that understands your entire workflow and thinks with you to tackle complex problems like coding and business strategy. Sign up and get 50% off your first 3 months of Claude Pro at https://claude.ai/tcr Linear: Linear is the system for modern product development. Nearly every AI company you've heard of is using Linear to build products. Get 6 months of Linear Business for free at: https://linear.app/tcr AGNTCY: AGNTCY is dropping code, specs, and services. Visit AGNTCY.org. Visit Outshift Internet of Agents Shopify: Shopify powers millions of businesses worldwide, handling 10% of U.S. e-commerce. With hundreds of templates, AI tools for product descriptions, and seamless marketing campaign creation, it's like having a design studio and marketing team in one. Start your $1/month trial today at https://shopify.com/cognitive PRODUCED BY: https://aipodcast.ing CHAPTERS: (00:00) About the Episode (04:30) Introducing Jim Collins (05:26) Antibiotic Resistance Primer (14:04) The Antibiotic Market Failure (18:45) AI Discovers Halicin (Part 1) (18:51) Sponsors: AssemblyAI Ad 1 | Claude (22:11) AI Discovers Halicin (Part 2) (30:58) The Economics of Discovery (39:10) Inside the AI Architecture (Part 1) (39:17) Sponsors: Linear | AGNTCY | Shopify (43:47) Inside the AI Architecture (Part 2) (01:00:13) Human-in-the-Loop Discovery (01:12:12) Novel Mechanisms & Properties (01:19:02) Future Applications & Risks (01:27:01) A Call to Action (01:28:04) Outro

In this episode of The Chad & Cheese Podcast, the boys interview Malcolm Frank, former president of Cognizant Digital and current CEO of Talent Genius, a platform focused on AI-driven talent acquisition. Frank, an Ohio native, discusses his extensive experience in technology and consulting, highlighting Cognizant's growth from 10,000 to over 300,000 employees. He traces AI's rise in business, noting its "slow, then sudden" impact since ChatGPT's 2022 debut. Frank critiques CEOs for layering AI onto outdated structures, leading to poor ROI, as shown in an MIT survey, and advocates for first-principles thinking to redesign processes. He sees recruiting transforming with AI, cutting sourcing time (e.g., scanning 7.5 million profiles instantly) and improving cultural fit analysis, though human recruiters remain vital for emotional connection. Frank warns of AI scaling biases faster than humans, necessitating strong governance to avoid issues like predatory lending seen in early AI experiments. He discusses Talent Genius's “Agent Powered” platform, which helps workers leverage AI to amplify skills (e.g., becoming “5x” more effective), drawing parallels to historical job shifts like the iceman's obsolescence. The lively discussion, peppered with humor about Davos and Buckeyes, emphasizes AI's potential to turbocharge talent management if thoughtfully integrated, urging listeners to visit talentgenius.io for more. Chapters 00:00 - Introduction to Malcolm Frank 01:56 - The Rise of AI and Its Impact 05:20 - Challenges in AI Implementation 09:02 - The Future of Recruiting with AI 12:53 - Investing in Employee Development 17:19 - The Role of AI in Talent Acquisition 21:16 - Big Tech vs. Niche Vendors in HR Tech 24:48 - The Evolution of ATS and Recruiting Tools 28:51 - Bias in AI and Its Implications 35:23 - AI's Impact on Blue Collar Jobs 37:39 - The Vision Behind Talent Genius

Kat Niewiadomska is a global Executive Coach and Leadership Development Consultant who blends her engineering, business and behavioral science background to help founders and entrepreneurs achieve sustainable success. She has over 15 years of experience working with startups, SME's, NGO's and multinational organizations. Kat is also the co-founder of Synaps Analytics, a data analytics company that measures social and leadership impact and ROI. Kat has over a decade of experience in consulting, training and coaching and has worked with startups, SME's, NGO's and multinational organizations on topics such as Creativity and Innovation, Design Thinking, Emotional Intelligence and Leadership. She also has 6 years of experience as a design engineer working on cutting edge technology with governmental, military and non-governmental organizations both in the United States and France. She was an Adjunct Professor and taught Entrepreneurship, Innovation and Design Thinking at top-rated universities in the Middle East. She holds a B.E. in Electrical Engineering from SUNY, New York, an M.S. in Engineering from MIT and a PhD in Environmental Sciences from the Sorbonne. She is also an award wining author and TEDx speaker, an aspiring triathlete, acrylic painter and a mom of 3. Find Kat Online LinkedIn: https://www.linkedin.com/in/katniewiadomska/ Co-Founder & CEO @ Synaps Analytics LLC: https://www.synapsanalytics.com/ Executive Coach and Leadership Consultant @ Audacity Activated Inc: https://www.audacityactivated.com/ Creator of the Entrepreneurial Failure Risk Index: https://failureindex.com/ If you're enjoying Entrepreneur's Enigma, please give me a review on the podcast directory of your choice. The show is on all of them and these reviews really help others find the show. iTunes: https://gmwd.us/itunes Podchaser: https://gmwd.us/podchaser TrueFans: https://gmwd.us/truefans Also, if you're getting value from the show and want to buy me a coffee, go to the show notes to get the link to get me a coffee to keep me awake, while I work on bringing you more great episodes to your ears. →  https://gmwd.us/buy-me-a-coffee Support me on TrueFans.fm → https://gmwd.us/truefans. Support The Show & Get Merch: https://shop.entrepreneursenigma.com Want to learn from a 15 year veteran? Check out the Podcast Mastery Community: https://www.skool.com/podcast-mastery/about Follow Seth Online: Instagram: https://instagram.com/s3th.me LinkedIn: https://www.linkedin.com/in/sethmgoldstein/ Seth On Mastodon: https://indieweb.social/@phillycodehound The Marketing Junto Newsletter: https://MarketingJunto.com Leave The Show A Voicemail: https://voiceline.app/ee Learn more about your ad choices. Visit megaphone.fm/adchoices

Mosharaf Chowdhury, associate professor at the University of Michigan and director of the ML Energy lab, and Dan Zhao, AI researcher at MIT, GoogleX, and Microsoft focused on AI for science and sustainable and energy-efficient AI, join Kevin Frazier, AI Innovation and Law Fellow at the University of Texas School of Law and a Senior Editor at Lawfare, to discuss the energy costs of AI. They break down exactly how much a energy fuels a single ChatGPT query, why this is difficult to figure out, how we might improve energy efficiency, and what kinds of policies might minimize AI's growing energy and environmental costs. Leo Wu provided excellent research assistance on this podcast. Read more from Mosharaf:https://ml.energy/ https://www.technologyreview.com/2025/05/20/1116327/ai-energy-usage-climate-footprint-big-tech/ Read more from Dan:https://arxiv.org/abs/2310.03003'https://arxiv.org/abs/2301.11581 Hosted on Acast. See acast.com/privacy for more information.

Entscheidungsdruck entfaltet Kraft oder lähmt: Führungskräfte verlieren Orientierung, wenn Unsicherheit dominiert und Information hält selten, was sie verspricht. Überforderung wird zur Blockade, Ratlosigkeit wächst, während alle nach Halt suchen und Fehlerangst Entscheidungen verlangsamt. Ein Kundenprojekt gerät ins Stocken, Lösungen entstehen erst durch echte Fokussierung und den Mut, Imperfektion zuzulassen. Wer sich Unterstützung holt und auf Selbstführung setzt, gewinnt neue Handlungsfähigkeit – auch in widersprüchlichen Zeiten. Du erfährst... ...wie Führungskräfte Entscheidungsverzögerungen überwinden und handlungsfähig bleiben. ...welche Rolle Selbstführung und externe Unterstützung in Krisenzeiten spielen. ...wie Kundenzentrierung und schnelle Etappenlösungen Unternehmen stabilisieren. __________________________ ||||| PERSONEN |||||

Stabilität über alles: Mit dieser Mentalität bremst die Bundesrepublik die schöpferische Zerstörung im Land. Drei Forscher zeigen, welche Folgen das für Wachstum und Wohlstand hat.

Die Tinte auf dem Vertrag von Sharm El-Sheikh ist trocken - für Donald Trump bricht eine neue Zeit an: „Gott segne den Nahen Osten“ sagte der US-Präsident während seiner Reise nach Israel und Ägypten. Dass die israelischen Geiseln endlich freigekommen sind, hat auch Tagesthemen-Moderator Ingo Zamperoni und seine Frau Jiffer Bourgouignon tief bewegt: „Ich glaube, man konnte das nicht anschauen, ohne Tränen in den Augen zu haben“, erzählt Jiffer über ihre Reaktionen während der Live-Übertragung der Freilassung. Am Tag nach den großen Emotionen analysieren die beiden Trumps Auftritte vor der Knesset und bei der Zeremonie am Roten Meer und was wohl von Trumps 20-Punkte-Friedensplan übrig bleiben wird, wenn nun die nächsten Schritte anstehen. Und blicken anschließend auch wieder über den Atlantik rüber - denn während sich Trump auf der Weltbühne als Friedensstifter präsentiert, handelt er innenpolitisch zunehmend alles andere als friedlich. Mit dramatischen Worten prangert er eine angeblich bürgerkriegsähnliche Lage in US-Großstädten an, die von Bürgermeistern der Demokratischen Partei regiert werden. So will er den Einsatz der Nationalgarde im Land rechtfertigen. Das sei Machtmissbrauch, kritisieren vor allem die Betroffenen und haben vor Gerichten erfolgreich geklagt. Die Mitarbeiter der Einwanderungsbehörde ICE suchen derweil weiterhin mit teils brutalen Mitteln nach illegalen Einwanderern. „Diese ICE-Raids durch den Einsatz der Nationalgarde zu flankieren, das ist nichts, wo man sagen würde, das ist Peace-Talk“, schätzt Ingo Trumps Innenpolitik ein. Erleben Sie den Podcast "Amerika, wir müssen reden!" live: Im Rahmen der Hamburger Woche der Pressefreiheit sind Ingo Zameroni und Jiffer Bourguignon am 4. November in der Zentralbibliothek Hamburg zu Gast. Der Eintritt ist frei, Teilnahme nur über Anmeldung: https://www.ndr.de/nachrichten/info/podcastlive-100.html Feedback und Fragen bitte an podcast@ndr.de Wie geht es weiter im Gazastreifen? https://www.tagesschau.de/ausland/asien/faq-gaza-nach-freilassungen-100.html Gericht verbietet Nationalgarde-Einsatz in Chicago https://www.tagesschau.de/ausland/amerika/nationalgarde-chicage-gericht-100.html Podcast-Tipp: 11KM der tageschau-Podcast über das Leben in Afghanistan https://1.ard.de/11KM_Afghanistan

Marty speaks with biochemist and astrobiologist William Bains on the topic of Dark Ecology, as a final chapter to our 4 previous episodes on this topic with Chris Beckett (Ep 56), Julius Csotonyi (Ep 57-58) and Adrian Tchaikovsky (Ep 59).  Dr. Bains is the author of “The Cosmic Zoo: Complex Life on Many Worlds”, and has earned degrees from the universities of Oxford, Warwick and Stanford, and has held positions at the University of Bath, MIT, Imperial College London, and in addition to founding a number of biotech start-up companies is now a senior research fellow in the Department of Physics and Astronomy at Cardiff University in the UK.  William is exactly the kind of person we love to speak with on this show as his expertise really expands and deepens some of ideas we've been talking about in contemporary science fiction.  Some of his recent papers carry titles like  "Prospects for detecting signs of life on exoplanets in the JWST era" and  "Astrobiological implications of the stability and reactivity of peptide nucleic acid (PNA) in concentrated sulfuric acid".  So that's the kind of thing we discuss in the following conversation.  In addition to expanding on the details of Adrian Tchaikovsky's worldbuilding in Shroud, we talk about the WOW signal in astronomy, the incoming 3I/ATLAS extrasolar object, and new experiments in high throughput chemistry and biochemistry.Send us a messageEmail: thescienceinthefiction@gmail.comFacebook: https://www.facebook.com/groups/743522660965257/

Monday, October 13th, 2025Today, former national security advisor John Bolton could be indicted as early as this week; Trump robs Peter to pay Paul without Congressional authorization; Donald's nominee for the Office of Special Counsel is a sex pest; a Republican has purchased Dominion voting machines; stocks tank as Trump extends China tariffs; Republicans want to gut a 50 year old law that protects sea life; Donald is scrambling to re-hire top CDC scientists he just fired; MIT rejects the regime's shakedown of nine major universities; a librarian fired in a dispute of LGBTQ+ books gets a massive settlement; the guy deploying troops against his own citizens loses the Nobel peace prize; and Allison and Dana deliver your Good News.Thank You, IQBARText DAILYBEANS to 64000 to get 20% off all IQBAR products, plus FREE shipping. Message and data rates may apply. Guest: Stephanie TellesStephanie Telles for ABQ City Council District 1@stephanieforabq - InstagramStephanie for ABQ - facebookStoriesJim Comey. Leticia James. Is John Bolton Next? | MuellerSheWrote.comCriminal charges against Bolton expected as early as next week | MSNBCTrump authorizes troop pay amid government shutdown | NBC NewsDominion Voting Systems sold to company run by former Republican election official | ABC NewsS&P and Nasdaq Slump as Stocks Fall on Trump China Tariff Threat | NYTRepublicans try to weaken 50-year-old law protecting whales, seals and polar bears | ABC NewsMAGA steams at Trump's Nobel snub | POLITICOPost by @grahamformaine.bsky.social — BlueskyTrump Administration Is Bringing Back Scores of C.D.C. Experts Fired in Error | NYTKey Trump nominee accused of sexual harassment | POLITICOMIT Rejects Special Funding Offer From Trump Administration | NYTWyoming library director fired amid book dispute reaches $700,000 settlement | NBC NewsGood TroubleCalifornia! YOU have your prop 50 ballots. Fill them out and return them ASAP.Yes On Prop 50 | CA Special Election Phone Banks - mobilize.us**October 20 Deadline -Petition of America First Legal Foundation for Rulemaking**October 18 - NoKings.org **Vote Yes 836 - Oklahoma**How to Organize a Bearing Witness Standout**Fire Kilmeade - foxfeedback@foxnews.com, Requests - Fox News**Indiana teacher snitch portal - Eyes on Education**Find Your Representative | house.gov, Contacting U.S. SenatorsFrom The Good NewsLISTERS: A Glimpse Into Extreme Birdwatching | YouTubeSpecial HCN access for current or former government employees - High Country NewsProject Mail StormThePrintedGarden.comDreams of Our Fathers | YouTube(Mark your calendar for November 14th, 2025 - Chicago, Illinois - Dana)Our Donation LinksNational Security Counselors - DonateMSW Media, Blue Wave California Victory Fund | ActBlueWhistleblowerAid.org/beansFederal workers - email AG at fedoath@pm.me and let me know what you're going to do, or just vent. I'm always here to listen. Find Upcoming Actions 50501 Movement, No Kings.org, Indivisible.orgDr. Allison Gill - Substack, BlueSky , TikTok, IG, TwitterDana Goldberg - BlueSky, Twitter, IG, facebook, danagoldberg.comMore from MSW Media - Shows - MSW Media, Cleanup On Aisle 45 pod, The Breakdown | SubstackReminder - you can see the pod pics if you become a Patron. The good news pics are at the bottom of the show notes of each Patreon episode! That's just one of the perks of subscribing! patreon.com/muellershewrote Our Donation LinksNational Security Counselors - DonateMSW Media, Blue Wave California Victory Fund | ActBlueWhistleblowerAid.org/beansFederal workers - feel free to email AG at fedoath@pm.me and let me know what you're going to do, or just vent. I'm always here to listen. Find Upcoming Actions 50501 Movement, No Kings.org, Indivisible.orgDr. Allison Gill - Substack, BlueSky , TikTok, IG, TwitterDana Goldberg - BlueSky, Twitter, IG, facebook, danagoldberg.comCheck out more from MSW Media - Shows - MSW Media, Cleanup On Aisle 45 pod, The Breakdown | SubstackShare your Good News or Good TroubleMSW Good News and Good TroubleHave some good news; a confession; or a correction to share?Good News & Confessions - The Daily Beanshttps://www.dailybeanspod.com/confessional/ Listener Survey:http://survey.podtrac.com/start-survey.aspx?pubid=BffJOlI7qQcF&ver=shortFollow the Podcast on Apple:The Daily Beans on Apple PodcastsWant to support the show and get it ad-free and early?The Daily Beans | SupercastThe Daily Beans & Mueller, She Wrote | PatreonThe Daily Beans | Apple Podcasts Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

0:00 Marjorie Taylor Greene explains real America First agenda w/ Tim Dillon! Robby Soave | RISING 9:54 Hamas frees living Israeli hostages; Knesset celebrates Trump | RISING 18:27 Adam Schiff blasts Trump, says he will not be intimidated by 'vengeance' | RISING 23:41 MIT rejects Trump Admin's deal for universities: A WIN for education! Lindsey Granger | RISING 33:29 George Stephanopoulos cuts off JD Vance, ends interview after clash over Homan allegations | RISING 42:04 Tim Burchett reveals naval officer's wild alleged UFO encounter underwater | RISING Learn more about your ad choices. Visit megaphone.fm/adchoices

Beau Wangtrakuldee is the founder and CEO of AmorSui, a science-backed medical supply brand bringing innovation, safety, and sustainability to the $58B PPE industry. A former scientist turned entrepreneur, Beau is reimagining protective apparel with clean chemistry, circular materials, and design that finally puts the user first.After a lab accident exposed the flaws in traditional PPE, Beau built AmorSui to bridge the gap between safety, comfort, and sustainability: offering PFAS-free, recyclable, and biobased alternatives trusted by global brands like Thermo Fisher Scientific and Benco Dental.Whether you're building a mission-driven ecommerce brand or rethinking your product's lifecycle, Beau shares a masterclass in turning real-world problems into scalable innovation, proving that circular design and commercial growth can coexist.In This Conversation We Discuss:[00:30] Intro[01:01] Building comfort and safety into every product[01:46] Creating a business from personal experience[04:37] Designing products people actually reuse[06:10] Validating ideas through real user stories[08:12] Raising capital before manufacturing begins[08:47] Allocating funds beyond first production run[09:45] Navigating minimum order quantity realities[10:32] Launching pre-sales with finished prototypes[11:04] Stay updated with new episodes[11:14] Balancing safety standards with speed to market[12:37] Episode Sponsors: Electric Eye & Heatmap[15:18] Marketing through word-of-mouth momentum[17:01] Refining targeting through early experiments[19:00] Discovering growth through customer feedback[21:34] Testing demand before building logistics[23:17] Learning quickly by shipping imperfect products[24:09] Focusing every decision on the end userResources:Subscribe to Honest Ecommerce on YoutubeModern PPE brand that protects people and the planet amorsui.com/Follow Beau Wangtrakuldee linkedin.com/in/beauwangtrakuldeeSchedule an intro call with one of our experts electriceye.io/connectClear, real-time data built for ecommerce optimization heatmap.com/honestIf you're enjoying the show, we'd love it if you left Honest Ecommerce a review on Apple Podcasts. It makes a huge impact on the success of the podcast, and we love reading every one of your reviews!

“I'm not one of these people who keeps the phone on, and the champagne in the fridge.” Peter Howitt certainly didn't seem to be expecting the news of his 2025 prize in economic sciences. In this call recorded just after the announcement, he talks to the Nobel Prize's Adam Smith about his longstanding friendship with fellow-laureate Philippe Aghion and how they started their collaboration in the conducive environment of MIT. “My future,” he concludes, “is going to involve more economics, and less golf, than I had anticipated!” © Nobel Prize Outreach. First reactions terms of use: https://www.nobelprize.org/ceremonies/streams-terms-of-use Hosted on Acast. See acast.com/privacy for more information.

Forsker-afsnit-alarm!: Martin Rosenlyst er forsker i astropartikelfysik og står foran et ophold på MIT, hvor han skal arbejde med nogle af universets største spørgsmål. I dagens afsnit taler vi om rejsen dertil, fra at vokse op med et talebesvær, der gjorde matematikken til det sprog, der gav mest mening, til at følge sin nysgerrighed hele vejen ind i forskningen. Vi snakker om CERN, partikelacceleratorer, simulationsteori, gud, tro og om at ligge alene på Grønlands indlandsis, fem dages vandring fra nærmeste civilisation, midt i et voldsomt angstanfald.Gå fornøjelse, Christian. Vil du høre resten? Så find hele episoden eksklusivt på Podimo:http://podimo.dk/christian Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Október 3-án Vlagyimir Putyin nyilvánosan is kiállt Orbán Viktor újraválasztása mellett. Mi ennek a politikai jelentősége? Mit jelent ez a kampány menetére nézve? Képes lehet az orosz államhatalom befolyásolni akár a választási kampány alakulását? Egyáltalán: hogyan lettek az ukránok a Fidesz kampányának főszereplői? Felidézzük az elmúlt négy év háborús kommunikációjának legfontosabb fordulópontjait és megpróbálunk választ adni ezekre a kérdésekre. A műsor második felében élőben kapcsoljuk Buda Péter biztonságpolitikai elemzőt. A stúdióban Rényi Pál Dániel és Takács Lili.See omnystudio.com/listener for privacy information.

Die 18-jährige Studentin Alice Sebold geht spätabends durch den Thornden Park. Plötzlich hört sie Schritte hinter sich. Ein Mann tritt aus der Dunkelheit und greift sie brutal an. Alice überlebt. Schwer verletzt schleppt sie sich zurück in ihr Studentenwohnheim. In den frühen Morgenstunden spricht sie mit der Polizei, durchsucht Fotos möglicher Täter. Doch der Mann, den sie beschreibt, ist nicht dabei.Fünf Monate später begegnet sie ihm dann auf der Straße und die Räder des Rechtssystems beginnen sich zu drehen. Ein Verfahren, ein Urteil, ein abgeschlossenes Kapitel. Zumindest scheinbar.Denn viele Jahre später macht Alice ihre Geschichte mit dem Buch Lucky öffentlich. Als das Buch verfilmt werden soll, tauchen erste Fragen auf. Über Erinnerungen, über Wahrheit und darüber, ob die Geschichte, an die alle glaubten, wirklich so geschehen ist.Heute erzählen wir euch den Fall von Alice Sebold und Anthony Broadwater, zwei Leben, die auf schmerzliche Weise miteinander verbunden sind und davon, wie ein einziges Verbrechen mehr als ein Opfer hinterlassen kann.Inhaltswarnung: Explizite Gewalt, Sexualisierte Gewalt, Justizskandal, RassismusDiesen Fall haben bereits live in der Thalia Universitätsbuchhandlung in Rostock aufgeführt. Es war ein wundervoller Abend, danke, an alle, die dabei waren

From flying F-16s over Iraq to testing Virgin Galactic's spaceplanes, Keith “Coma” Colmer has lived one of the most diverse and impactful careers in modern aviation. Raised near John Wayne's ranch in rural Arizona, he rose from an Air Force ROTC cadet at MIT to a combat and test pilot shaping the future of flight. In this episode, Coma shares untold stories from flying GPS satellites during Desert Storm, developing the Litening and Sniper pods, pioneering electronic warfare systems like the ALQ-213, and leading Virgin Galactic's early spaceflight test team. He also opens up about leadership lessons from the Air National Guard, directing operations at Gulfstream Aerospace, and why he now flies floatplanes in the Pacific Northwest “just for the fun of it.” This is an incredible deep dive into flight testing, innovation, and the passion that keeps pilots in the sky long after the mission ends.

Worum geht's: Um das erste offizielle Rocky-Videospiel zu demonstrieren, pilgerten die Pixelkino-Prügelknaben zur Stay Forever Convention Süd 2025 nach Karlsruhe: Der Kampf des Jahrhunderts zwischen dem »Austrian Stallion« und der »Fresse aus Hesse« fand dort live am ColecoVision statt. In dieser Podcast-Version des Spektakels könnt ihr alle sechs Runden miterleben. Anhand der Rocky-Filmserie schlagen wir uns durch drei Jahrzehnte Spielegeschichte – von kruden Arcade-Kloppereien (1976) bis zu den 3D-Rockys der PS2-Ära (2006). Der Film: Rocky III (1982) von Sylvester Stallone. Das Spiel: Rocky Super Action Boxing (1983) von Coleco. Pixelkino ist ein seit 2023 laufender Podcast von und mit Heinrich Lenhardt und Christian Genzel. Das Thema einer jeden Folge ist immer ein bekannter Film und die dazugehörige Spielumsetzung oder andersherum – bekanntes Spiel und dazugehörige Filmumsetzung. Mit dem Start von Staffel 3 wechselte das Pixelkino für mindestens eine Staffel (6 Folgen) ins Stay-Forever-Portfolio und wird exklusiv zweimonatlich für unsere Unterstützer und Unterstützerinnen auf Patreon/Steady ausgestrahlt. Das ist immer neues Material, keine Wiederveröffentlichung bisheriger Folgen.

This is a free preview of a paid episode. To hear more, visit www.louiseperry.co.ukMy guest today is Linda Griffith, Professor of Biological and Mechanical Engineering at MIT and director of the Center for Gynepathology Research in Boston. Linda is a leading world expert on endometriosis, our subject today. We spoke about her own experiences with the disease, why it's so poorly understood, the challenges of diagnosis, the impact on wo…

Between 1946 and 1953, at a Massachusetts institution called the Walter E. Fernald State School, dozens of boys were recruited into something called a “Science Club.” They were promised special perks — better food, baseball games, trips to the beach. What they weren't told was that their breakfast oatmeal and milk were secretly laced with radioactive iron and calcium. The so-called nutritional study was designed by scientists from MIT, funded in part by the U.S. Atomic Energy Commission, and co-sponsored by Quaker Oats, which supplied the cereal. The goal was to measure how well the body absorbed minerals from food — but the method violated every basic rule of ethics and consent. The children, many labeled “feebleminded” or “morons” by the state, were wards of Massachusetts — boys without parents, without rights, and without the ability to refuse. Some were even injected with radioactive materials in follow-up experiments. None were told what was happening to them. When the truth came out decades later, public outrage was immediate. Survivors like Fred Boyce came forward, saying the greatest harm wasn't the radiation — it was being treated like an object, not a person. In 1998, MIT and Quaker Oats settled a class-action lawsuit for $1.85 million, and President Bill Clinton issued an apology on behalf of the federal government for Cold War-era human radiation testing. But behind the headlines is a bigger story — about power, secrecy, and the belief that science justifies anything. In this episode, we dig deep into the Fernald radioactive oatmeal experiments — what really happened, who was responsible, what became of the victims, and how it changed human-subject research forever. Hosted by Tony Brueski. Subscribe for more longform true-crime investigations that expose the hidden side of power, psychology, and justice. #HiddenKillers #TrueCrimePodcast #FernaldExperiment #RadioactiveOatmeal #ColdWarHistory #HumanExperimentation #MIT #QuakerOats #InstitutionalAbuse #ScienceEthics Want to comment and watch this podcast as a video? Check out our YouTube Channel. https://www.youtube.com/@hiddenkillerspod Instagram https://www.instagram.com/hiddenkillerspod/ Facebook https://www.facebook.com/hiddenkillerspod/ Tik-Tok https://www.tiktok.com/@hiddenkillerspod X Twitter https://x.com/tonybpod Listen Ad-Free On Apple Podcasts Here: https://podcasts.apple.com/us/podcast/true-crime-today-premium-plus-ad-free-advance-episode/id1705422872

Between 1946 and 1953, at a Massachusetts institution called the Walter E. Fernald State School, dozens of boys were recruited into something called a “Science Club.” They were promised special perks — better food, baseball games, trips to the beach. What they weren't told was that their breakfast oatmeal and milk were secretly laced with radioactive iron and calcium. The so-called nutritional study was designed by scientists from MIT, funded in part by the U.S. Atomic Energy Commission, and co-sponsored by Quaker Oats, which supplied the cereal. The goal was to measure how well the body absorbed minerals from food — but the method violated every basic rule of ethics and consent. The children, many labeled “feebleminded” or “morons” by the state, were wards of Massachusetts — boys without parents, without rights, and without the ability to refuse. Some were even injected with radioactive materials in follow-up experiments. None were told what was happening to them. When the truth came out decades later, public outrage was immediate. Survivors like Fred Boyce came forward, saying the greatest harm wasn't the radiation — it was being treated like an object, not a person. In 1998, MIT and Quaker Oats settled a class-action lawsuit for $1.85 million, and President Bill Clinton issued an apology on behalf of the federal government for Cold War-era human radiation testing. But behind the headlines is a bigger story — about power, secrecy, and the belief that science justifies anything. In this episode, we dig deep into the Fernald radioactive oatmeal experiments — what really happened, who was responsible, what became of the victims, and how it changed human-subject research forever. Hosted by Tony Brueski. Subscribe for more longform true-crime investigations that expose the hidden side of power, psychology, and justice. #HiddenKillers #TrueCrimePodcast #FernaldExperiment #RadioactiveOatmeal #ColdWarHistory #HumanExperimentation #MIT #QuakerOats #InstitutionalAbuse #ScienceEthics Want to comment and watch this podcast as a video? Check out our YouTube Channel. https://www.youtube.com/@hiddenkillerspod Instagram https://www.instagram.com/hiddenkillerspod/ Facebook https://www.facebook.com/hiddenkillerspod/ Tik-Tok https://www.tiktok.com/@hiddenkillerspod X Twitter https://x.com/tonybpod Listen Ad-Free On Apple Podcasts Here: https://podcasts.apple.com/us/podcast/true-crime-today-premium-plus-ad-free-advance-episode/id1705422872

Nobel Prize; China Rare Earth; Deficit; MIT; Qatar; Drill; Woke Church; Bad Bunny | Yaron Brook ShowOctober 10, 2025

Dave Blundin has co-founded 23 companies, co-hosts the Moonshots podcast, runs the VC firm Link Ventures, teaches at MIT, and has been building neural networks since the 1980s. His take: “[AI is] under-hyped. It's absolutely going to change the world in the next couple of years more than any change in human history. There's nothing even vaguely comparable to it.” — (7:37) “Stop sleeping. Rush to everything you do.” (15:16) Why he started building neural nets at MIT in the 1980s (16:19) Should you finish college or start a business? (20:38) Why best friends are the best co-founders (25:00) San Francisco is still king, but Boston is AI startup central (28:06) “The chip shortage is going to be incredibly bad.” (34:26) The AI energy shortage (36:32) Are we in an AI bubble? (55:44) The case for human immortality before 2050 (1:02:00) Advice for first-time founders (and second-time, and 23rd-time) — Want to connect?