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L'interoperabilità è diventata un elemento cruciale nel panorama tecnologico moderno. Se fino a qualche decennio fa erano poche le aziende che potevano creare innovazione a 360 gradi imponendosi sul mercato con ecosistemi completi, oggi assistiamo a un proliferare di aziende specializzate in tecnologie specifiche che stanno diventando leader nei rispettivi settori. Questa evoluzione ha reso fondamentale la capacità di sistemi diversi di collaborare efficacemente, scambiandosi dati e informazioni in modo trasparente: trovare standard comuni è ormai imprescindibile. In questa puntata approfondiamo il tema dell'interoperabilità in vari ambiti: dall'hardware industriale e medico alla domotica, fino ai servizi software e alla Pubblica Amministrazione.Nella sezione delle notizie parliamo di Microsoft che ha reso WSL (Windows Subsystem for Linux) open source, del "Take It Down Act" firmato negli USA anche contro i deepfake e dei satelliti FireSat per il monitoraggio degli incendi boschivi.--Indice--00:00 - Introduzione01:00 - Microsoft rende WSL open source (HDBlog.it, Luca Martinelli)02:04 - In USA è stata firmata la legge federale contro i deepfake (TheGuardian.com, Davide Fasoli)03:19 - I satelliti FireSat per il monitoraggio degli incendi (Google Research, Matteo Gallo)04:55 - Un futuro interoperabile, dall'Industria 4.0 ai servizi per il cittadino (Luca Martinelli)17:01 - Conclusione--Testo--Leggi la trascrizione: https://www.dentrolatecnologia.it/S7E21#testo--Contatti--• www.dentrolatecnologia.it• Instagram (@dentrolatecnologia)• Telegram (@dentrolatecnologia)• YouTube (@dentrolatecnologia)• redazione@dentrolatecnologia.it--Immagini--• Foto copertina: Macrovector su Freepik--Brani--• Ecstasy by Rabbit Theft• Capsized by Tollef

"Bitcoin NON è inevitabile: il suo vero valore non sono i 21 milioni, non è la riserva di valore, ma sono la privacy e la resistenza alla censura. Se lo lasceremo controllare ai governi e alle corporation avrà fallito". A parlare è Thaddeus Dryja, creatore del Lighnting Network e nuovo idolo del BIP SHOW.Inoltre: i "dazi a cazzi" di Trump penalizzano il mining, la fine della task force anti crypto in USA, l'analisi dei flussi trimestrali dell'OAM.It's showtime!

/ Rotterdam / Cruiseboot / Mensen ontvluchten 4 jaar Trump op een cruiseboot / reservaat voor welgestelden / In USA problemen vercommercialiseren / Blijft monarchie in Nederland? / Online werken op een boot / Drijvende huizen ivm water overlast / Kantoor op een boot ?/ /JACK&JOZEF zijn 29 maart 2025 in het Theater (Wekkekerpand Schiedam) Je toegangskaart €7,50 kan je bestellen via www.theateraandeschie.nl/voorstelling/jack-jozef / De Engelse versie www.JACKJOZEF.com / / Sponsor: IBV Consultancy, AndreArt.nl en JPSystems / / Op YouTube.com/@podcastgemist kan je PodcastGemist zien, op Spotify en andere streamingdiensten kan je naar PodcastGemist luisteren / / Heb je een vraag? Wil je ons uitnodigen bij je thuis? Of in je bedrijf voor bedrijfspresentaties, conferenties, teambuilding of andere events? Mail naar info@PodcastGemist.nl / / Voor actuele informatie kijk je op www.PodcastGemist.nl /

Wall Street rimbalza, ma chiude settimana in calo; In Usa creati solo 12mila posti di lavoro a ottobre; Fed verso taglio di 25pb; Apple in calo, Amazon in rialzo all'indomani dei conti; Usa2024: testa a testa Harris-Trump in Pennsylvania  Learn more about your ad choices. Visit megaphone.fm/adchoices

Lo avevamo anticipato e puntualmente è arrivato il nuovo modello di OpenAI che ragiona in modo più evoluto, ecco cosa sa fare. Novità importante anche per Gemini, per gli utenti Android. In USA, per la prima volta, l'AI viene usata nella pubblica amministrazione. Nuove informazioni e dettagli su iPhone 16 Learn more about your ad choices. Visit megaphone.fm/adchoices

(01:48) Il nero non impegna: AfD vince ma non governa (31:10) In USA è cominciata la risacca dell'inclusione? (53:19) Il 62% del PNRR è ancora da spendere negli ultimi 8 mesi Learn more about your ad choices. Visit megaphone.fm/adchoices

The host's of CSN The Network Podcast return this week to discuss USA Olympic basketball, WNBA, college football and the NFL. The host's begin the show by discussing college football as camp has now started. We discussed our favorite story lines in college football for our teams, we discussed the highly anticipated EA Sports College Football 25, and we also discussed what camp means for football as it shows that games will be aired very soon. In the NFL, we posed the question which brand of football would we prefer, college or NFL? We also discussed the start of the 49ers training camp and their contract situations with multiple star players. We then discussed Caleb Williams and his attempt to get his contract paid to his LLC instead of his personal account, because of the Illinois tax regulations for businesses. In USA basketball, we posed the question, has the rest of the world caught up to the USA in basketball? We also discussed LeBron James being named the first men's basketball player to be named the flag bearer for the olympics and where he ranks as an olympic gold medalist. In the WNBA. we discussed the WNBA all star weekend and all of the relevant topics regarding the sport. As always we appreciate the support, please continue to like, subscribe, share and view the content.

Wenn er kommt, soll er helfen, die nächste Pandemie besser zu bewältigen, am besten für die ganze Welt. Entsprechend viele Streitpunkte gibt es bei den Verhandlungen bei der WHO in Genf. Ausserdem: Wie der Luftverkehr klimafreundlicher wird: Ein Überblick mit Einordnung. 00:00 Schlagzeilen 00:44 Der Pandemievertrag der WHO: Wenn er kommt, soll er viel leisten, nämlich helfen die nächste Pandemie besser zu bewältigen, am besten für die ganze Welt. Streitpunkte gibt es bei den Verhandlungen bei der WHO in Genf unter den 194 Mitgliedsländern viele: Wer zahlt? Wer liefert Informationen? Und: Wie lässt sich eine internationale Organisation mit wirksamen Mitteln ausstatten, ohne die Souveränität der Staaten zu gefährden? 07:05 Meldungen: Cannabis schadet dem Gehirn von Teenagern; Internationaler Seegerichtshof unterstützt kleine Inselstaaten; Mammutknochen in Weinkeller entdeckt. 14:09 Wie der Luftverkehr klimafreundlicher wird: In USA gibt es heute erste Flughafen-Tankstellen für synthetisches Kerosin. Mit dieser Alternative zum üblichen Kerosin stossen Flugzeuge bis zu 40 Prozent weniger Abgaspartikel aus. Dies reduziert deutlich die von Flugzeugen verursachten Kondensstreifen am Himmel, die im Luftverkehr klimaschädlicher sind als der CO2-Ausstoss. 20:05 Wie zukunftsweisend ist der alternative Sprit für klimaneutrales Fliegen? Und welche anderen Lösungen zeichnen sich ab? Ein Überblick mit Einordnung. Mehr zum Wissenschaftsmagazin und Links zu Studien: https://www.srf.ch/wissenschaftsmagazin .

FastLetter - Una fonte buona dalla quale aggiornarsia cura di Giorgio TavernitiN. 45 - 20 Maggio 2024Di cosa parliamo* YouTube si mangia la TV* YouTube raggiungerà la Qualità di Netflix tramite Top Creator?* YouTube è “solo” la TV del Mondo?* Questa storia dell'Algoritmo deve finire* Il Multiformato e la Fluidità* Il Futuro della Content Creation per le Aziende* I miei ultimi video* SalutiPremessa: questa edizione è quasi divisa in due. La prossima settimana uscirà il numero dal titolo “Perché stiamo SBAGLIANDO tutti a fare Content Marketing”. Da quello che stiamo per vedere su YouTube ci sono considerazioni importanti, mi occorre però un'altra edizione.Nell'ultimo mese ho pubblicato numerosi video su argomenti che mi interessano molto, dalla SEO all'AI, da YouTube alla Tecnologia. Alla fine di questa edizione ho creato una zona dal titolo “I miei ultimi video” dove faccio un recap ordinato perché parliamo di diverse ore di video e nuove rubriche che voglio presentarvi.Inoltre, ho ripreso le live e consiglio a tutte le persone interessate a seguirmi su Telegram dove è più facile trovare questi link. L'ultima live ha destato parecchio interesse in chat: La SEO nel 2025: dalla SGE (AI Overview) alla Search AI. E sono sicuro che le prossime avranno lo stesso livello:* Intelligenza Artificiale, Embeddings, SEO e Screaming Frog con Giovanni Sacheli, Enrico Altavilla e Alessio Pomaro. Forse altri ospiti in arrivo.* Analisi dei vostri canali YouTube - Parte 2 Non ho invece fatto alcun approfondimento - e non lo farò - sugli eventi di OpenAI e Google I/O. Google ha lanciato molte cose interessanti, ma l'evento è stato molto confusionario. Entrambi però non mi hanno sorpreso o fatto gridare a chissà che cosa. Trovo che gli annunci fatti siano semplicemente prevedibili, la direzione degli sviluppi è chiara. Man mano che proverò le singole funzionalità farò dei video se le riterrò interessanti. Tuffiamoci nell'edizione odierna.YOUTUBE SI MANGIA LA TVSono passati 5 anni da quando ho definito YouTube come la TV del Mondo. I video hanno sopraffatto un po' tutto intanto e su FastForward spiego come si stanno mangiando Internet. In questi ultimi anni le generazioni sono cambiate e gli effetti sono devastanti: nel mondo sono arrivati i video brevi e loro usano meno frequentemente Stampa e TV rispetto alle generazioni passate, definendo nuovi parametri anche dell'autorevolezza. Conoscete qualcuno di più autorevole di Marques Brownlee nel suo settore che venga dai media tradizionali? No..Ovviamente, è una estremizzazione per far comprendere che qualcosa è cambiato.I media che oggi vengono visti un po' staccati perderanno questi paletti proprio perché le nuove generazioni li considerano allo stesso livello nella loro vita, non come noi che consideriamo la TV una cosa e YouTube un'altra.Per esempio. Prime Video produrrà i Beast Games: 5 milioni di dollari in premio per i giochi di MrBeast (N°2 al mondo per numero di iscritti al suo canale YouTube), il montepremi più alto per un gioco televisivo. Televisivo?Boh. Non è televisivo ma lo è. YouTube è il posto dove stanno succedendo cose incredibili e sebbene qualcuno storce il naso perché dentro YouTube troviamo di tutto (la critica è più rivolta agli Shorts) vuole dire che non ha capito cosa sta accadendo.YouTube in questi anni non ha sfidato solo le piattaforme digitali come Twitch, TikTok, Spotify e Apple. Ma anche la TV e Netflix&Co. E lo ha fatto anche con vari modelli di abbonamento, dal Premium a YouTube TV.La potenza distributiva sui dispositivi di YouTube però è unica: Desktop, APP e Smart TV. Se prendete le altre piattaforme non hanno questa caratteristica. In USA il 45% guarda YouTube dalla Smart TV. Perché? Perché ci sono funzionalità diverse anche. Come l'esperienza sportiva e gli abbonamenti ai canali pay della TV tradizionale, cosa che è arrivata in beta anche in Inghilterra e Germania. E attraverso YouTube è possibile fare ADV nella TV tradizionale in USA.In questi ultimi anni YouTube ha dimostrato di riuscire a competere su più fronti, non solo in ambito Digital, ma tentando di mettere piede in luoghi diversi dal Digitale puro. E in effetti i loro uffici commerciali quando vendono l'ADV parlano un linguaggio da pubblicità televisiva.YouTube, DNA Google, non compete con una realtà, ma con tutte. Perché YouTube vuole tutto, vuole essere la piattaforma del futuro. E l'offerta che sta tentando di dare è un'offerta ricca, con tutto dentro.Chi ha un canale YouTube tradizionale si lamenta, però non considera che senza tutte queste cose YouTube oggi avrebbe perso parecchio terreno, parecchia audience e saremmo qui a dire che sono stati degli incapaci.Invece anche nello Streaming Watchtime di Nielsen, YouTube è prima battendo Neflix, Prime Video, Hulu e Disney+.Dal mio punto di vista ci aspetta un mondo dove YouTube tenterà di mangiarsi anche le produzioni televisive. E competerà anche sulla qualità con Netflix.YOUTUBE RAGGIUNGERÀ LA QUALITÀ DI NETFLIX GRAZIE A TOP CREATOR?Non solo in USA, Inghilterra, Germania è possibile abbonarsi ai canali televisivi tradizionali tramite YouTube, non solo si può fare pubblicità in TV tramite YouTube, non solo YouTube produce film e serie, la cosa impressionante è la qualità dei singoli canali YouTube. Che sta per arrivare ad un livello mai visto prima.Ovviamente questo avviene perché YouTube è stata in grado di creare un sistema virtuoso di monetizzazione per avere Creator Indipendenti.Le produzioni di video dei canali YouTube stanno raggiungendo una qualità da Netflix.Vi faccio un esempio citato da The Hollywood Report:Un video che si è meritato il commento di YouTube stessa:Nonostante ad un primo impatto sembrerebbe un canale alla MrBeast, andando ad aprire il video non c'è la frenesia del noto YouTuber (che comunque sta tentando di diminuire e ne parleremo a breve). C'è un'altra roba: una qualità impressionante.Stanno aumentato i canali che offrono una qualità davvero importante. Certo, la migliore produzione Netflix è imbattibile. Ma ricordiamoci che le evoluzioni umane avvengono anche sulla percezione della qualità del pubblico, che cambia di generazione in generazione.La domanda di prima su Marques Brownlee dovrebbe far un po' riflettere. La percezione di Autorevolezza cambia nel tempo, così come i Media, così come la Qualità, così come noi.E ci sono dei momenti dove queste cose subiscono una grande accelerata. Su YouTube USA sta avvenendo che la qualità si è notevolmente alzata. In Italia, con un impatto diverso, avvenne una cosa simile con Vittima degli Eventi di Claudio di Biagio (che sarà al WMF!). Ovvio che stiamo parlando di due cose diverse, di epoche diverse, sto solo dicendo che ci sono dei momenti in cui tutti si accorgono che si può fare.La grande differenza dell'ultimo periodo è che stanno nascendo canali che mantengono una qualità elevata in molti video, con una produzione televisiva. Non un singolo video, non un caso. Ma un canale che si avvicina ad essere una serie TV.Questo sta cambiando YouTube, sta cambiando i Media e cambierà anche il pubblico perché ovviamente al pubblico piace. YOUTUBE È “SOLO” LA TV DEL MONDO?Guardando il report di MBLM, YouTube è il 5° brand più amato al mondo. Per trovare un altro social dovete scendere fino alla posizione 54, dove c'è Twitter destinato a scendere. Poi abbiamo Facebook (119), TikTok (154), LinkedIn (181) e Instagram (182).Molte classifiche dei siti più visitati al mondo mettono Google primo e YouTube secondo. Se guardiamo il report di We Are Social, YouTube è l'app più usata al mondo dopo TikTok e Netflix sia per attività che per tempo speso (slide 113).Nella Musica YouTube è secondo dietro a Spotify. Se prendiamo i podcast, nell'ultimo anno YouTube ha scalzato tutti. Se prendiamo i Podcast più ascoltati al mondo sono quasi tutti dei Video Podcast e YouTube è la piattaforma preferita. Questo avviene perché YouTube ha una marea di forme di monetizzazione molto apprezzate anche dai Podcaster : si guadagna di più e si guadagna in modi diversi.Prendiamo invece lo streaming? YouTube vs Twitch:Non c'è paragone. YouTube è leader. Su Twitch ci sono più canali che fanno streaming, ma i numeri sono bassi. Anche sulla lingua e sulle categorie di streaming si nota come YouTube è molto meglio con più diversità. Bisogna sommare i follower dei primi 26 canali Twitch per raggiungere MrBeast.Sui video brevi sappi

Today's show reviews major developments in various global economies: In USA, the Fed's latest decision to keep interest rates at current levels + its decision to start buying back US Treasuries (QE by another name perhaps?). Why the liquidity injection? Answer: growing concerns about US banks in 2025? Next, is China growing again or not? The idiocy of US policy toward China as Blinken and Yellen attack it economically but request it intervene on behalf of US with Russia and Ukraine. What's happening in Europe with France announcing it will send troops to Ukraine as EU (and UK) economy stagnates. ECB chair, La Garde, worries about seizing $260B Russian assets. How this may lead to de-dollarization and de-euroization. What's happening in Argentina as its peso is devalued by 50%. A deeper look at Office Commercial Real Estate in the USA, US Govt Debt, and US Treasury's record level of current bond buying.

In Usa e Cina tutto come previsto, in Europa un po’ meno

OnderwerpenDe Vision Pro is beschikbaar in de USA:MKBHD heeft 3 filmpjes: unboxing | eerste indrukken en how-to | reviewNilay Patel van The Verge heeft een vreemd gezicht

Another episode of the Independent Thinking Show for @FifthWrist Radio. @FifthWrist Independent Thinking Show is a place dedicate to showcasing the great people doing interesting and cool things in the world of horology.   In this special episode, Roman (@TimesRomanAU) sits down for a chat with one of his horological heroes and indie watchmaking royalty - master watchmaker and clockmaker Martin Braun, and a previous guest and friend of FifthWrist Scott Goldman (@goldmanstagram1). Our fascinating conversation captures the intricacies of indie horology, the evolution of Martin's horology career, and the trials and tribulations of early independent watchmaking in the 1990s and early 2000s.  We get insights into Martin's approach to unique designs, astronomical influences in his watches, his (not positive) experience with the Frank Muller, and the current relaunch of the EOS sunrise and sunset watch. This episode is packed with rich stories and insights into the world of watchmaking, giving listeners a close-up look into the complexities and the artistry involved in creating timepieces. The iconic Martin Braun EOS model (with customisable sunrise and sunset indicators set for the owner's location) is now relaunched and available. In USA, you can contact Scott (@goldmanstagram1) directly on scott@scottgoldman.net or +1 3109637867 to discuss how to buy the Martin Braun EOS now! It is a MAGICAL WATCH!! Outside North America, you can also check out the Schaumburg Watch website for details. Theme Music for 2023: The Wrong Time by Silent Partner (via YouTube Free Music Channel)   To join our crew group chat then please email us at contact@fifthwrist.com and if you have time please leave us a review wherever you listen to our podcast.   We hope you enjoy listening to this episode as much as we enjoyed making it!   Stay On Time Follow us on Instagram: ⁠@FifthWrist⁠  #fifthwrist #fifthwristradio #fifthwristradiopodcast 

Dr. Mahdi Sheikh and Dr. David Zaridze join Dr. Shannon Westin to discuss how quitting smoking after diagnosis may impact survival in kidney cancer. TRANSCRIPT  The guest on this podcast episode has no disclosures to declare. Dr. Shannon Westin: Hello everyone, and welcome to another episode of JCO After Hours. This is the podcast where we get in-depth on manuscripts that have been published in the Journal of Clinical Oncology. As always, I'm your host, Shannon Westin, Gynecologic Oncologist and Social Media Editor for the JCO. And I am so excited to be here today. We are going to be discussing the paper, “Smoking Cessation After Diagnosis of Kidney Cancer Is Associated With Reduced Risk of Mortality and Cancer Progression: A Prospective Cohort Study,” which was published in the JCO on March 29, 2023. And this very intriguing paper, I have two of the major authors from this paper. First is Mahdi Sheikh, who is a scientist and epidemiologist at the International Agency for Research on Cancer, the World Health Organization in Lyon, France. Welcome, Dr. Sheikh. Dr. Mahdi Sheikh: Thank you very much, Dr. Westin, and thanks for having us. Dr. Shannon Westin: And then with Dr. Sheikh is Dr. David Zaridze. He is the Director of the Department of Clinical Epidemiology at the N.N. Blokhin Russian Cancer Research Center in Moscow and also the President of the Russian Cancer Society. We are with greatness today. Dr. David Zaridze: Thank you. Thank you very much. Nice to be with you. Dr. Shannon Westin: Very nice to be with the two of you. So, let's get started. I first wanted to just level set. Could one of you review just the overall incidence of kidney cancer and what proportion of patients with kidney cancer are known to be smokers at diagnosis? Dr. David Zaridze: The figures I'm going to present are rates. They are adjusted to standard world population. Why am I saying that? Because in America you sometimes use adjustment to the US population. These figures will be different from what you are accustomed to see. Okay, incidence of kidney cancer in Russia, in men, 14.1 per 100,000. I compare this with the United States of America, men, 16.5. Very small difference. Women in Russia, 8 per 100,000. In the United States of America, 8.8 per 100,000 of population. Exactly the same. Very close. These rates are sort of high-ish, but there are very high rates, for example, in the Czech Republic, where rates are more than 20 and other Central European countries. In Russia, kidney cancer mortality in men is 6 per 100,000. In USA, 3 per 100,000. In women in Russia, 1.9. In the United States, 1.3. I would say that there is a difference in mortality in men, not much in women. The incidence of kidney cancer is increasing in Russia sharply, sharply. Since 1990 it has increased - it's tripled. It increased from 5 per 100,000 in 1990 to 14 per 100,000 in 2019. Mortality is stable or declining. This is suggesting that kidney cancer is overdiagnosed in Russia and probably elsewhere. But this is not a problem of our discussion now. The frequency of the prevalence of smoking in kidney cancer patients. It is estimated that 15% to 20% of patients with kidney cancer smoke. In Russia, we have results only from our study. 18% of patients smoked at admission to our cancer center. Dr. Shannon Westin: Got it. Okay, good. Well, that's really helpful, especially to those of us that don't take care of patients with kidney cancer every day. It helps us just understand. And I guess the next question is what do we know about the impact of tobacco cessation on the risk of kidney cancer? So you were talking about that increasing incidence. How does tobacco cessation impact that? Dr. Mahdi Sheikh: Tobacco smoking is a known risk factor for kidney cancer and an estimated 17% of the kidney cancer burden worldwide can be attributed to tobacco smoking. There is a recent meta-analysis of 56 studies that was published a few years ago that clearly showed a dose-response relationship between smoking and kidney cancer, meaning that the more cigarettes a day you smoke, the risk of kidney cancer will go up. For example, the risk that was shown for five cigarettes per day was 20%. It goes up until 70% for 30 cigarettes per day. And also with a duration, the more years you smoke, the risk for kidney cancer will go higher. However, the good news is that when you quit smoking, there is strong evidence that the risk for developing kidney cancer will be lower compared to if you continue smoking. And there is some evidence that shows again dose-response relationship, meaning that the more years you spend in quitting smoking, the lower your risk would be for developing kidney cancer compared to if you continue smoking. So this is not only about renal cancer or kidney cancer but also true about many other cancer sites as well. Dr. Shannon Westin: Okay, that's super helpful. And then I guess prior to your study that we're about to talk about, did we have any information on what happens when patients quit smoking after their diagnosis? Any limitations to those data that were available? Dr. David Zaridze: You mean the data which was prior our study? You know, the negative effect of smoking after diagnosis has been shown nearly three decades ago. The information exists already for thirty years, but it was largely ignored not only in clinical practice but also in clinical trials. And I have to stress that in clinical trials this information is still ignored. I came across these studies and decided to review them some time ago. All they were case-control studies and to my knowledge, none of them assessed the effect of quitting smoking. I decided to review these studies and included this review in my book, Smoking: A Major Cause of Cancer, which was published in 2012 and was dedicated to Professor Richard Doll's anniversary. In fact, this was a stimulus for the study we are discussing. And in fact, the component of this study we are discussing today was built in and baked into the existing cohort study to which we added the active follow-up component for assessing the changes in smoking habit and disease status. Dr. Mahdi Sheikh: If you review the evidence, before publishing this study just like a few years ago, we find that there are many studies published talking about the effects of smoking cessation on cancer survival. However, as David mentioned when you go deep into these studies, you'll find a lot of limitations. First of all, most of these studies are retrospective studies, which means that either case-control or retrospective course that patients developed the outcome, and then some investigators came to see their records to assess or ask family members before they developed the outcomes. There are a lot of biases with these types of studies. And with the epidemiologic study, perspective study that we did, has less limitations compared to retrospective ones. Another one is that when we go into the study you see, they only assess a small number of patients, small sample size. Some studies just assess 10 smokers, some assess like 30. By this study we try to assess a large number of smokers who quit smoking after diagnosis. Another limitation is that– First, let's see what exposure and what setting we are talking about. We're talking about smoking which is a very dynamic behavior. People quit smoking and they relapse smoking and they quit smoking and so on. So if you access this exposure for only a limited time, for example, for one year, then you may miss what happens after that which results in misclassification of some of the participants. So repeated assessment was not done in other studies that we did here in this study. Another one, you are talking about special setting patients who are diagnosed with cancer. These patients have special circumstances, they have treatments, they have family support, they might go under the stress of cancer, and all these different stages at diagnosis. And most studies that are available, they didn't account for this. They didn't adjust or they didn't try to understand the role of these compounding factors, as we call it in epidemiology, on that, the thing that we're trying to address. And a prospective study, as I said, long follow-up time. Even the very few prospective studies that were available for other cancer sites that have only one year or maximum two years of follow-up with this type of exposure, so it is important to follow them for a long time. Another thing I would say was exposure assessment. Not only did we repeatedly try to assess exposure among participants, but try to call the people– David and his team who did the study in the field, called the participants and tried to ask the family members and sometimes their physicians about their smoking behaviors. When you go to current evidence you see, mostly smoking behavior was assessed using the record that is available like treatment records or patient records, which again has some limitations if you do not assess exposure among qualified participants. Finally, we're talking about a dynamic behavior in the follow-ups. Some people might change smoking. But there is a very important thing, in this study, we also collect at the time of quitting smoking. There's a very important thing in statistics we call Survivorship Bias, meaning that, if you were assessing an exposure doing the follow-up and if you do not pay attention to this, you will assess an exposure that is a proxy of people who lived longer. Meaning that people have enough time, they have a long time, and those who have longer time, will have more time to quit smoking. And then you will be assessing this, actually, not the exposure, but you're only assessing people who quit smoking, and then whatever you assess, you would end up with a beneficial effect. But if you have the time of quitting smoking and follow up and all these statistical things and lower sample size, you are able to account for this very very important bias in epidemiology. Dr. Shannon Westin: Before we go further, I'd love for just a bit of a description of exactly how you laid out your study to really add to where this data are so limited around survival and tobacco cessation. So maybe review the primary/secondary objectives, basic design, just to make sure our listeners are all on the same page. Dr. David Zaridze: The study has classical prospective cohort design that the study, which was basically a basic study, in which the new component was built in. This study used a user's questionnaire-based exposure assessment and molecular epidemiologic approach. I mean that, in addition to the questionnaire approach, we collected blood and tumor tissues for molecular studies. All patients with kidney cancer admitted to the cancer center were interviewed at admission before receiving any treatment. A structured lifestyle questionnaire was used. Participants were asked about their lifetime smoking history which included questions about the duration and frequency of smoking cigarettes, the average number of cigarettes smoked every day. They were also asked about their lifetime history of alcohol drinking. The questions included questions about exposures to carcinogens other than smoking, and health conditions, including chronic kidney diseases, hypertension, diabetes and so on. Height and weight were measured. Today, this study generated and continues to generate plenty of results and papers published in most prestigious journals such as Nature Genetics, for example. So, as you know, we started from 2012, we started the follow up of the cohort members, we were focusing on Moscow residents and the follow-up includes regular annual contacts with the patients personally or via telephone or with patients' household members, etc. Again, we collected information about changes in smoking behavior and disease status. We also used information from the regional cancer registry to confirm the information obtained from patients. The average period of follow up was eight years. And this is quite a long follow-up. Repeated assessment of smoking status reduces the likelihood that exposure to smoking was misclassified. However, regrettably, the self-reported information on smoking was not supported by biochemical tests, for example, by blood cotinine testing. To my knowledge, this is the only prospective cohort study in patients with cancer, not only with kidney cancer that have collected data on participants' smoking status prospectively for quite a long time. The average follow-up time was eight years. Dr. Shannon Westin: That was incredible. That definitely caught my eye. And I was looking, I was like, “Oh, how many did they lose?” And you guys kept 80-100% of the patients. I just was so impressed by that. And now hearing the mechanisms in which you did that, it makes sense. You were very diligent, multiple ways to contact patients and confirm the data. So you really are to be congratulated for the work that you're able to achieve. Dr. Sheikh, I'd love to hear, you talked a little bit about how some of the studies didn't really think about confounding variables. Can you kind of highlight some of the confounding variables that you all controlled for in order to really assess the impact of the cessation on survival? Dr. Mahdi Sheikh: Thanks to the high-quality data and also the large sample size and the way the study was designed, we were able to adjust for a lot of confounding. So we tried to adjust for all these things. So we used three approaches. The first approach was adjustment. When you ran this in the analysis, we tried a statistical model, we tried to adjust for these confounders like age, sex, treatment, socioeconomic status, smoking intensity, alcohol, and other factors. This is one effect, one approach. The second approach was stratification, meaning that we come and see the effect within people who have been diagnosed with only earlier stage tumors to see if the effect among people with earlier stage tumors differs with the effect that we see among people with higher stage tumors. But again, if you read the paper, you see that we saw the protective effects of smoking cessation on both groups of people, those who were diagnosed at earlier stages and those who were diagnosed at later stages. And also heavy smokers or mild to moderate smokers, again, we tried stratified analysis excluding those heavy smokers and saw the effect, again, among those who were light smokers or moderate smokers and also with the heavy smokers. I want to say that we tried all these types of analytical approaches and we really saw the protective effects across all patient subgroups. Finally, I talked again about the survivorship bias. So we used really strict statistical approaches to address this confounding, and because we had the time of quitting, we had the follow up time and all these things. And, again, whatever we did in the study we still could see the effects of smoking and all this is due to the good design, the large sample size, and the good questionnaire data that we have. Dr. Shannon Westin: That's awesome. I think, of course, now let's get to the bottom line. 40% reported that they quit smoking after diagnosis with none relapsing during the time period. And what did you see was the impact on overall survival as well as cancer-specific survival? Dr. Mahdi Sheikh: So we tried several outcomes - overall survival, cancer-specific survival, but also progression-free survival. And then because we had the large sample size we could assess all this. Interestingly, we saw the effect on all the three outcomes that we assessed. So the overall survival was better among those during the quitting time and also the cancer-specific survival was also better and also progression-free survival was better among all these participants. Dr. Shannon Westin: I think most people that have read this paper - and if you haven't read this paper you should run to read it right now - I really was impressed with that kind of clear benefit across cancer-specific mentality across all subgroups regardless of how much they smoked. So I don't know why you get a sense of like, “Oh, if you smoke a little bit you wouldn't see as big of an impact,” but a very clear impact. And I would love to hear why you think smoking negatively impacts these outcomes. How does the cessation help? This is a perfect time for that. Dr. Mahdi Sheikh: When we review the evidence about how smoking cessation may be beneficial for patients, for the survivorship of patients with cancer, we come to five mechanisms that are suggested in the literature. So the first one can be, is suggested, that is altered cancer biology. Smoke and tobacco smoke contain numerous carcinogens and mutagens. So it has been shown that cancer cells that are exposed to tobacco smoke, they may become more aggressive and the risk of metastasis might go higher and also, angiogenesis and all other effects on the biology of cancer cells. So it may affect the cancer cell biology. Another suggested mechanism might be altered immune response. So tobacco smoking affects the immune system and then the immune response among those who are exposed to tobacco might be affected by tobacco smoking. So their response to the cancer cells but also other bacteria, viruses, and other things might be affected as well. The third possible mechanism suggested altered drug metabolism. It has been shown that tobacco smoke and smoking can affect some of the enzymes that have metabolic responsibilities and metabolism of the drugs. So that can affect the washout period for the drug. It might not stay enough in the blood or vice versa as well. It might affect the toxicity. There is some evidence about this. The fourth mechanism suggested is about increasing treating-related complications or treatment-related complications. People who smoke have delayed wound healing, they have more complications, the surgery, the time they spend at the hospital might be longer. And this is also part of which smoking may affect the outcomes that we saw here. And finally, that is we are talking about tobacco smoking and patients with cancer are human beings with all these systems. So we know that smoking causes damage to the cardiovascular system, to the pulmonary system and also to the lungs and other things. So this is why we see different outcomes are affected by cancer. Dr. David Zaridze: I was impressed by the data that exposure to tobacco smoke condensate induces changes in tumor microenvironment. For example, it inhibits formation of interferons, interferon alpha and gamma, inhibits the migration to tumor microenvironment of the immune cells. The number of CD8+ T lymphocytes, T killers, are significantly lower in the tumor microenvironment of current smokers compared to former smokers and never smokers. And even more interestingly, the number of PD-L1+ cells are also lower in the tumor microenvironment of current smokers than former or never smokers. This is probably very important in terms of effectiveness of impairment by smoking of the immunotherapeutic approaches in cancer treatment. Dr. Shannon Westin: That's very important and we know the microenvironment has a huge impact on just the way the cells respond to treatment and develop resistance and so that makes a lot of sense. Okay, well, this has been amazing and I think one thing that you just said just struck me, Dr. Sheikh, that you've obviously shown this in lung cancer and you're looking at this in other cancers. I guess the question is: What should we be doing? How should we be implementing tobacco cessation efforts across all cancer diagnoses to help all patients that have really any diagnosis of cancer? Dr. David Zaridze: Let me first underline the clinical importance of these results. The benefits from quitting smoking are comparable or even superior to those recorded in the clinical trials of modern kidney cancer treatments such as immune checkpoint inhibitors. I refer to the results of pivotal trials in advanced renal cell cancer in the frontline setting and these results were reported at ASCO Meeting 2023 recently in May. If you compare the results of our study with results of these pivotal trials, it is very impressive. It is clear that our findings strengthen the case for making tobacco cessation treatment a standard part of the routine health care for all people with cancer, however, smoking is still quite high in cancer patients. And I would like to quote Peter Shields who is saying that, in the United States,10% to 50% of cancer patients smoke. As far as Russia is concerned, in our study, 80% of kidney cancer patients smoke, and in our lung cancer study, 58% of cancer patients smoke.  The barrier is that the oncologists do not believe or are accepting with a great deal of skepticism the results of our study. They don't believe the idea that anything else besides surgical, radiological, or medical treatment could improve the outlook of cancer patients. It's difficult for them to apprehend. Many of them think that smoking cessation after diagnosis is simply a waste of time. Many patients simply don't know that smoking cessation after diagnosis may be beneficial for them. In addition, they are pessimistic and they feel discouraged to quit smoking, as they might think it is too late. I would like to quote my favorite quote: “Smoking cessation treatment has to become the fourth pillar of cancer treatment, one that could affect cancer treatment outcomes as powerfully as surgery, chemotherapy, or radiation therapy.” This is Dr. Fiore, 2019. Dr. Shannon Westin: Thank you so much. And Dr. Sheikh, anything to add there around cessation efforts? Dr. Mahdi Sheikh: As we saw the results of these studies that smoking cessation is feasible and it is accessible at a minimum cost for many patients, it should really be integrated in the  management of patients with cancer. It is feasible, it is cheap, it is accessible. But unfortunately, when we review the evidence we see that only less than half of the physicians, like around 40% of physicians, send the patients to tobacco smoking cessation services. And even some do not discuss this issue. And as David mentioned, they do not know the effect of smoking cessation. So when you go through these studies to find the major barriers, in addition to what David had mentioned, we find two important points. First one is lack of education or experience in providing tobacco cessation interventions among those who deal with patients with cancer. So they do not have the education. And second is lack of available resources for referrals. Now we're not only talking about the United States but also many other countries even high-income countries, we do not see the resources for referrals on smoking cessation services in cancer care settings. The take home message probably from this study and also from these barriers, would be for three groups. First, for the policymakers, we would recommend sustainable funding should be dedicated to tobacco cessation services. As we saw, the effect is huge and seems to be a very big effect and it is cheap so why not implement this smoking cessation service within cancer care settings.  And the second one, tobacco treatment training programs for healthcare providers. This is also very, very important that we try to implement this training program in the curriculum of healthcare providers, especially those who deal with cancers and tobacco-related outcomes. And also for physicians, we recommend that physicians should assess and address tobacco use in all patients with cancer. They should talk about this topic and also show the benefits of quitting smoking. And patients with cancer who smoke should be supported to stop smoking at any time and each visit after diagnosis is not like some time pass, as we saw, all patient subgroups could benefit from smoking cessation. This is important.  But something also very, very important that we shouldn't forget that cancer itself causes a lot of fear and anxiety and stress. And smoking cessation sometimes may be associated with stress and more anxiety. So it is very, very important to think about this point and provide the psychosocial support to patients who quit smoking. Sometimes they may relapse just because of the fear and anxiety they have. So it's not only showing the evidence, but also supporting these patients, telling them how to do that and also supporting them emotionally and also psychosocially. And finally for the patients, I would like to give this message that we see and we know that it is never too late to quit smoking. As David said, patients may feel like, “It is too late now I've developed cancers,” but no, it's really not too late. And if you quit smoking at any time after diagnosis, you would benefit a lot from smoking cessation. Dr. David Zaridze: In the United States there are guidelines, several guidelines for smoking cessation, specifically for cancer patients because smoking cessation in cancer patients is very different from smoking cessation in general population. In the general population, we more or less succeeded, I would say, and we have to look now at this direction to the smoking cessation in cancer patients. And this is a message to WHO, that countries, members of WHO, based on the recommendation guidelines of WHO, develop their own specific guidelines for smoking cessation in cancer patients. And that should be used in all cancer clinics and that should be a must, absolutely important part of anti-cancer treatment. And as I already told, it should be the fourth pillar in cancer treatment, as treatment, as surgery, chemotherapy and radiation. Dr. Shannon Westin: Thank you both. That was such a great discussion, and I hope that we've convinced everyone that this is a critical effort that they need to be addressing every day.  I just want to thank everyone who listened. This has been "Smoking Cessation after Diagnosis of Kidney Cancers Associated with Reduced Risk of Mortality and Cancer Progression: A Prospective Cohort Study", again published in the JCO on March 29, 2023. Thank you guys again for listening to JCO After Hours. Please check out our other podcast offerings. You can check them out on the website or wherever you get your podcasts and let us know what you think about the podcast on Twitter. Dr. David Zaridze: Thank you. Dr. Mahdi Sheikh: Thank you very much.  The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions.   Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement.  

In USA la Corte Superma ha abolito le cosiddette "Affirmative Actions" il cui scopo è quello di contrastare la discriminazione: ma è veramente così? Ne parliamo con Michele Boldrin! LOGONAUTI in sconto ancora per poche ore ➤➤➤ https://www.alessandrodeconcini.com/tutti-i-corsi/logonauti ⬇⬇⬇SOTTO TROVI INFORMAZIONI IMPORTANTI⬇⬇ LE FONTI CITATE: 1) https://www.questionegiustizia.it/articolo/affirmative-action-game-over-per-la-scotus - 2) https://youtu.be/R-0NsJ6RgJ0 Abbonati al canale da 0,99 al mese ➤➤➤ https://bit.ly/memberdufer I prossimi eventi dal vivo ➤➤➤ https://www.dailycogito.com/eventi Impara ad argomentare bene ➤➤➤ https://www.dailycogito.com/video-corso/ Il mio ultimo libro per Feltrinelli ➤➤➤ https://amzn.to/3jmCYpQ Entra nella Community ➤➤➤ https://www.patreon.com/rickdufer La newsletter gratuita ➤➤➤ http://eepurl.com/c-LKfz Daily Cogito su Spotify ➤➤➤ http://bit.ly/DailySpoty Canale Discord (chat per abbonati) ➤➤➤ https://discord.gg/pSVdzMB Tutti i miei libri ➤➤➤ https://www.dailycogito.com/libri/ Il negozio (felpe, tazze, maglie e altro) ➤➤➤ https://www.dailycogito.org/ #affirmativeaction #dufereboldrin #rickdufer INSTAGRAM: https://instagram.com/rickdufer INSTAGRAM di Daily Cogito: https://instagram.com/dailycogito TELEGRAM: http://bit.ly/DuFerTelegram FACEBOOK: http://bit.ly/duferfb LINKEDIN: https://www.linkedin.com/pub/riccardo-dal-ferro/31/845/b14 -------------------------------------------------------------------------------------------- Chi sono io: https://www.dailycogito.com/rick-dufer/ -------------------------------------------------------------------------------------------- La sigla è stata prodotta da Freaknchic: https://www.freaknchic.it/ La voce è della divina Romina Falconi, la produzione del divino Immanuel Casto. A cura di Stefano Maggiore. Learn more about your ad choices. Visit megaphone.fm/adchoices

"Sposati e figlia": in Cina progetti pilota per incentivare matrimonio e gravidanza. La realtà della gravidanza adolescenziale nella Repubblica Dominicana: "Non ho finito il liceo. Ora ne pago il prezzo". In Usa ok al farmaco non ormonale contro i sintomi da menopausa. Cuba: la comunità LGBTQI+ marcia per celebrare l'adozione del matrimonio tra persone dello stesso sesso.https://www.radiobullets.com/notiziari/16-maggio-2023-notizie-donne-lgbtq-mondo-podcast/

This week Alex and Mary discuss what it's like to travel with a chronic illness. They share tips for their preparation and planning for their upcoming trip to Germany. Listen on our website, www.downthereaware.com/podcast, or wherever you get your podcasts. #Podcast #Spotify #Anchor #research #advocacy #travel #Germany #medications #preparations #chronicillness #compressionsocks #Lasix #mobility #blood sugar #hcm #diabetes Stay Connected Email Us: downthereaware@gmail.com Instagram:@downthereaware Facebook: Down There Aware Twitter: @downthereaware Pinterest: Down There Aware TikTok: Down There Aware Episode Highlights Intro [0:13] Welcome Back! [1:24] Chronic illness travel prep [4:50] Checking in with the cardiologist [5:20] Compression socks [6:05] Lasix and frequent bathroom breaks [6:55] Restroom accessibility in Europe [8:00] Refrigerated medications [8:48] Upgraded to lie-flat accommodations [10:30] Mobility on airplane [11:45] Snacks to control blood sugar [12:22] Medications in carry-on luggage [12:55] Organization [14:10] Sadie Mae and Uncle Will [15:12] In USA docs limited in out of state RXs [15:45] Alex's travel packets [16:55] Shout out to Steve and Victoria [17:21] Dress for destination weather [17:55] Menstruating on a long trip [19:05] Flight Attendant requests, if needed [19:55] Atlanta airport [21:10] Think ahead [22:28] “Give yourself grace.” [22:42] Pace out the itinerary [23:40] 5-week series [23:54] Sadie Mae joins us [25:03] Thanks for listening! [25:39] Summary Keywords Podcast, Spotify, Anchor, research, travel, Germany, medications, preparations, chronic illness, compression socks, Lasix, mobility, blood sugar, HCM, diabetes --- Send in a voice message: https://anchor.fm/downthereaware/message

Host Johnny Punish welcomes VT's Dr. Kevin Barrett. Together they responsibly discuss the current state of the global anti-vax movement, what we learned in the aftermath of the pandemic, the modern merits of using vaccines across the globe and how all of this affects our global population of 8 billion people.IMPORTANT DISCLOSURE: This is a responsible independent open forum conversation as it relates to foreign policy around the world. This is NOT a scientific data driven discussion and should NOT be used to determine whether a vaccine should be used or not.  For such information, please consult your doctor and your government Health agencies.  In USA, please consult  the Center for Disease Control ( CDC) at their web site:  https://www.cdc.gov/Dr. Kevin Barrett, a Ph.D. Arabist-Islamologist is one of America's best-known critics of the War on Terror. He is the host of TRUTH JIHAD RADIO; a hard driving weekly radio show funded by listener subscriptions at Substack and the weekly news roundup FALSE FLAG WEEKLY NEWS (FFWN). He also has appeared many times on Fox, CNN, PBS, and other broadcast outlets, and has inspired feature stories and op-eds in the New York Times, the Christian Science Monitor, the Chicago Tribune, and other leading publications. Dr. Barrett has taught at colleges and universities in San Francisco, Paris, and Wisconsin; where he ran for Congress in 2008. He currently works as a nonprofit organizer, author, and talk radio host.SHOP OFFICIAL VT MERCH

2 MEDIA CONFIRMATIONS : Attorney General Merrick Garland's announcement of a special counsel to investigate Biden — like with Trump , China protested the passage of a U.S. Navy destroyer through the Taiwan Strait - as predicted by Clairvoyant Stoyanka Staikova in her Ebook publ. Dec.16,2022 : New E-book by Clairvoyant Stoyanka Staikova : PSYCHIC PREDICTIONS 2022 /2023 for : Vice President Kamala Harris, Republican Senator Bill Hagerty, Senator Josh Hawley, Senator John Hoeven, Elon Musk , Hunter Biden, Ron DeSantis, Yevgeny Prigozhin (Wagner Group) Author : Stoyanka Staikova Published : December 16, 2022 2022 Copyrights Dimitrinka Staikova, Stoyanka Staikova, Ivelina Staikova https://books.apple.com/us/book/psychic-predictions-2022-for-vice-president-kamala/id6445158578?ls=1 TABLE OF CONTENTS : https://hottestnewspredictions.blogspot.com/2022/12/new-e-book-by-clairvoyant-stoyanka.html ONLY A SMALL PART OF CLAIRVOYANT/PSYCHIC READING FOR : 6. Hunter Biden (Son of President Joe Biden) - Clairvoyant/Psychic predictions December 3,2022 - His business, Threat by Prison? When Joe Biden will be in danger?… - by Clairvoyant Stoyanka Staikova Visit our E-book Store , Blogs and Websites: How to order a Clairvoyant reading : http://clairvoyantDimitrinkaStaikova.weebly.com http://sites.Google.com/site/dimitrinkastaikova http://HottestNewsPredictions.blogspot.com http://ivstaikova.wixsite.com/clairvoyant …. January 2023 - USA and Russia will fight for a big water basin. In USA the Democrats will be investigated.(MEDIA CONFIRMATION 1) I see unrests and riots, protests connected with ships.(MEDIA CONFIRMATION 2) January/February 2023 - Hunter Biden will be….. MEDIA CONFIRMATIONS : MEDIA CONFIRMATION 1 Attorney General Merrick Garland's announcement of a special counsel to investigate Biden — like with Trump … January 13,2023 https://www.msnbc.com/the-reidout/reidout-blog/garland-special-counsel-biden-trump-rcna65767 ***************************** MEDIA CONFIRMATION 2 Taiwan's Tsai Visits Base as China Protests US Ship Passage January 6,2023 …..rival China protested the passage of a U.S. Navy destroyer through the Taiwan Strait, as tensions between the sides showed no sign of abating in the new year. https://thediplomat.com/2023/01/taiwans-tsai-visits-base-as-china-protests-us-ship-passage/ ************************ FIND SOME OF OUR EBOOKS IN APPLE BOOKS : https://books.apple.com/bg/author/dimitrinka-staikova/id1040330467 EBOOK STORE : BOOKS PUBLISHED YEAR 2022 Our Latest Ebooks : New Ebook : Parade of 69 Clairvoyant / Psychic Predictions with 139 Media Confirmations for Year 2022. World Predictions that came true for : Midterms 2022, Queen Elizabeth's death, Putin , Health diagnosis of Celebrities …. By Clairvoyants : Dimitrinka Staikova , Stoyanka Staikova, Ivelina Staikova Published January 2,2023 Table of Contents : https://clairvoyantdimitrinkastaikova.weebly.com/hottestnewspredictions/new-ebook-parade-of-69-clairvoyant-psychic-predictions-with-139-media-confirmations-for-year-2022-world-predictions-that-came-true-for-midterms-2022-queen-elizabeths-death-putin-health-diagnosis-of-celebrities-by-clairvoyants-dimitri ************Click here to read more : https://hottestnewspredictions.blogspot.com/2023/01/2-media-confirmations-attorney-general.html

Subscribe to my youtube for a chance to win a free flight: https://www.youtube.com/channel/UC-OhQIZMdPdENPlAVZuo-MA find me here: https://linktr.ee/BoldPerceptionsPodcast This was recorded in August, 2022. My thoughts on big news stories: Poland over taking UK (British plumbing in Poland), Canadian Trans Shop Teacher, Martha's Vineyard Immigration, 3rd World Business Hustler's Using Cloud LLC's In USA, & more.

In USA gli elettrodomestici vanno a 110, nel resto del mondo al doppio. Come mai? Io sono Gianpiero Kesten, per gli amici Jam. Mi trovi ogni giorno in onda su Radio Popolare e in podcast su Cose Molto Umane. —

Ein Wort mit 36 Buchstaben? Dominic versteht nicht, wieso Dirk da nicht sofort drauf kommt. Aber was soll's, wir verstehen im Moment ziemlich wenig von dem, was auf der Welt passiert. Nur 5% der Deutsch*innen finden Brusthaar attraktiv. Boris Johnson ist - fast - weg. Er will nur noch ein wenig Premier bleiben, damit er im schicken Schloss heiraten kann. In USA gibt es weitere Shootings. Diesmal sogar ziemlich nahe an Dominic's Wohnort in Chicago und am 4. Juli. Shinzo Abe wurde auf einer Wahlkampfbühne ermordet. Vom Abtreibungsgesetz in USA wollen wir garnicht sprechen. Was ist eigentlich los hier, Freunde? Gut, dass wir uns weiter gut verstehen. Dominic ist nach Episode 123 endlich wieder aufgewacht und Dirk hat's ihm nicht übel genommen. Und so haben wir diesmal einen sehr bunten Strauss an Themen - auch positiven. Die erste schwarze Frau ist Präsidentin einen NFL Teams, Dominic's Rad ist überraschender Weise Tubeless, Boris ist - fast - weg, Dirk hat im Filmquiz ordentlich abgeschnitten und: Top Gun: Maverick ist all das, was sich Dominic erhofft hat. Und noch zwei, drei Schippen mehr :-) Episode 124? Lohnt sich! Also hört und schaut rein und abonniert uns auf: Apple Podcasts: https://podcasts.apple.com/de/podcast/ist-doch-wurscht-wie-der-podcast-heisst/id1500941965 Spotify: https://open.spotify.com/show/2jORFqugpKOkmyL8EnZK6r?si=vQ_hvXKwQbehIdiwez03Dw Youtube: https://www.youtube.com/playlist?list=PLHug0m47v3pz67oMLWUu7aqkIGb5DCAmV #istdochwurschtwiederpodcastheisst #produktivität #biohacking #biohack #corona #coronavirus #biotech #mainz #chicago #filme #serien #bücher #podcastlife #podcasting #podcaster #applepodcasts #tubeless #lksg #highlandpark #shinzoabe #candor #brusthaar #topgunmaverick

1 in 10 people over 40 in the UK now have Type 2 Diabetes. In USA 11.3% of the total population now have the disease including many children. In this fun & engaging episode we talk to Ainsley Duncombe about his diagnosis, initially being in denial & then how with advice from his Doctor he used simple & consistent lifestyle change to reverse his diagnosis, lose 5 stone (70lbs) & totally turn his life around. This is a frank & honest conversation that will act as inspiration for anyone who needs to hear this information. It's also inspiring for anyone looking to make a lifestyle change as Ainsley talks with humour about what is really required & how becoming more healthy doesn't have to be boring.

In USA il rovesciamento della Roe v. Wade rischia di portare alla proscrizione dell'aborto in 28 stati. L'articolo commentato: https://www.nytimes.com/2022/05/10/opinion/roe-overturn-consequences.html Leggi il mio nuovo libro "Seneca tra gli zombie" ➤➤➤ https://amzn.to/3J0cPE2  Il nostro nuovo sito ➤➤➤ https://www.dailycogito.com/  Feed va in live su Twitch dal lun al ven alle 12 ed esce in podcast 24 ore dopo. Le live si tengono qui: https://www.twitch.tv/dailycogito  Segui anche Daily Cogito, "l'altro" podcast: https://open.spotify.com/show/3CPV6sZxGV3fVuDLbR9uWh  Gli eventi dal vivo ➤➤➤ https://rickdufer.com/eventi/ Il canale Youtube ➤➤➤ https://www.youtube.com/c/RiccardoDalFerro  La mia newsletter ➤➤➤ http://eepurl.com/c-LKfz La Community di Patreon ➤➤➤ https://www.patreon.com/rickdufer La chat di Discord ➤➤➤ https://discord.gg/vs3reA2k Instagram ➤➤➤ https://www.instagram.com/rickdufer/ Tutti i miei libri ➤➤➤ http://bit.ly/libdufer Il nostro negozio ➤➤➤ https://www.dailycogito.org/ Le musiche sono tratte da Epidemic Sound Learn more about your ad choices. Visit megaphone.fm/adchoices

Asketic co Founder Miķelis Baštiks talking with Head of “Printful” Marketing Raitis Puriņš, about growing a marketing team, building and monetizing your audience.M: Much has already been said about the growth of Printful, but I find your growth as the Marketing Team Leader even more interesting. You started from a very small team of five, now you are more than 100. There are many things to unpack. How to lead a team of five and then switch to a much larger team is a conversation of its own. But how has the daily life changed for you personally? I don't know how much you have reflected upon it yourself, but it would be interesting to hear.R: Since day one my position was the Head of Marketing Unit at Printful, however, when you have a team of five, you're not really a manager. The whole office consisted of 30 or so employees, I was number 35. You're not a manager, you learn to become one afterwards. In the beginning you're thrown into unknown waters and you try to swim out. Along the way you learn to become a manager. The first and most difficult realization is the ability to delegate and trust others. When you really become a manager, you think, okay, this person can do this instead of me. He might do it slower at first or take a different approach, but he will catch on. At first, I always put 100% trust into a person when I give a task. It's not like I let them sink or swim, instead I become a beacon that provides help and checks in to see if he's on the right track. Afterwards he has to grow by himself and you witness the progress. Trust is something to be applied to your own colleagues. M: How does it look in daily life? Do you have daily, weekly check-ins? It's clear you have to trust and provide freedom, but there has to be some accountability. Where have you found the balance?R: We have a framework, at the company there's a presentation “How not to die at Printful”. The idea is that it's better to manage a team of fifty or a project, since the company is so big and one project encompasses a large amount of people. There are a few ways you can look at that. One framework provides that every person has its own goal that he has come here to do and he has to achieve in 3 months, 6 months. He knows what he has to complete. One step further, everyone has a number that drives him. The goal of my team could be revenue. You can influence any team, when you set them a number that they are responsible for. If it's the amount of new clients in Australia, then in becomes your drive and all your activities within the project are focused on that. You never come and talk randomly; you always focus on your goal. Managers don't have to keep everything on their mind - it's all written down, you just check in and see whether your team is on the right track.M: There are so many teams. If one team learns something or tests something, are there any systems for not making the same mistakes twice? Is there a way to transfer the know-how of one team to another when there are so many?R: We provide a blueprint or a framework of previous successful approaches, so you don't have to do your own trial and error; instead you have an outline for your new project. In a rapidly growing company, the only constant is change. You have to be okay with facing changes. Not just because you feel like it, but with purpose to be able to work better. You can't lead a team otherwise, whether those are 5 people or 100. Your manager can change or something else. I know that even I have to constantly keep learning. The rules keep changing, and marketing changes too. I actually like it, the discomfort of not knowing something. No one taught me at school how to lead a marketing team of 100 people. If someone knows such school, let me know. Otherwise you just do you best.M: Of course you learn a lot of things along the way, but can you identify a few things that have helped you on the journey from a single digit team to a three digit team. How did your life look before and how does it look now?R: The main thing that I also remind my project colleagues is that you have to ensure you're your partners share accountability for what you are working on. Another thing I remind my team is that there's no such thing as over-communication, especially internal over-communication. We previously had a situation when the IT team came to me and said that an e-mail should be sent out about an update. Okay, when are you going to launch it? Yesterday. So you were kept out of the loop, because it was assumed that you could do this very quickly anyways. It's important to ensure accountability so that you are aware about a project from day one and can contribute. We also have a huge client support team, more than 200 people globally. The company has to ensure constant internal communication about what you're going to do and what projects are happening, the communication is needed above all. The bigger the team gets, the more important it becomes.M: You once mentioned personal growth and how you sometimes write to marketing managers of big companies to ask something, and most of the time you actually receive answers. Is it something you would do in other areas? Meaning, proactively apply the example of a predecessor. And those times when you have received an answer, what have you learned from your predecessors in different companies, but in the same category or position?R: I have never studied marketing, I know almost no theory, and therefore all I've learned comes from other colleagues, also from my previous workplaces. I don't even remember who gave me the idea that you need a mentor. It's less about learning. When teams are of similar size, we switch charts. It was one of my challenges when my team reached 50 members. Okay, I need a structure for scaling or I will die and won't be able to manage it all. You find out what each team is doing, why it's so large, what works, what doesn't. Secondly, you switch agencies and tools. That allows you to adapt it to yourself. I've also joined several groups, there's a DGMG community for B2B marketing. You can ask your question to the crowd or just search for account based marketing, which isn't a well-known term in Latvia. I don't even know who I could ask that in Latvia. This allows you to gain more from real people who have done this, instead from a blog post, where you don't know if this information has been used in practice.M: What else has helped you to learn and grow along the way? This is a cool example of reaching out and learning from the experience of others. But is there anything else?R: Experiments, for example. Often we don't know if something would work and get good results. You just try and see whether it would work. You learn from mistakes. There are projects from last year where I have lost more than 100 000 dollars, without bringing any gain to the company. But I know I have spent several millions that have benefitted us.M: If you could go get coffee with three marketing people from around the world, who would they be?R: I'm more interested in branding right now. I would like to understand performance checks, I like to measure all technical things. If you're spending a lot of money for Super Bowl ads, you need a good justification for that and need to know how to do it correctly. From the branding point of view, my favourite is Coca-Cola. It's the reason why Santa Claus is wearing a red suit. Amazing! Also Apple. The product plays a big part of it, but they're also doing cool things with the brand.M: If you're more interested in branding now, could you unpack the topics that you're interested in?R: Many say that brand comes from the management. At Printful, the management is me. If I want to invest a bigger team, resources or money in this, then I need strong arguments for why we're going to do this. We'll see the results after three, four years, so why do we need to invest a large amount of money, since the market is huge. I still can't do this. It's not like we don't have a brand. The brand is everything that the company has done all these years. But I'm still missing something for us to scale and do it correctly. The right people, the right team? I don't know.M: You said there are 8 regions. Is the brand the same everywhere or do you build it differently for each region?R: We don't think about branding in each region that much, we like the framework “jobs to be done”. We try to find a person who we can help in achieving what he wants.M: Can you tell me more about the framework “jobs to be done”? How do you implement it in practice?R: First, you want to create an e-commerce shop, maybe you have an Instagram following you want to sell to or an existing business, or you want to create a merch line. Second, you want to order something for yourself. We enable you to do that easily, but you need to find answers to many questions. Who will you sell the shirt to? Do you have a design to print? How will you integrate it? For how much will you sell? Then you have to bring people to the website to buy something. A side-product from all this is that we educate clients. The marketing team is teaching others about marketing. All our resources are directed this way. It's much more beneficial to think about the person's dream than to think about benefitting from them driving a BWM. That's why we're very focused on this work. M: You have mentioned content marketing as one of the things you're doing. Do you still think it's working? When looking at the marketing landscape, do you see other things to focus on in the future? R: Content marketing is everywhere, including what we're doing. It's something you polish and put out. Content marketing can be measured in many different ways. The best effect is when any text that we publish in a blog or on website gets indexed on Google. That enables you to first find Printful in organic results just by searching. In content marketing you also create your image. I, by being in podcasts, am creating an image of being an expert on some topic, which makes people want to talk to me. It's similar for companies. If you create content about something, people will have an opinion about you, which goes along with branding. Okay, they know about this thing, probably I should work with them to ensure quality. You just have to create content, otherwise you won't understand what you have to do here. The idea of starting an e-commerce shop is great, but there a lot of ways to do it. The content helps us guide the creator through this tunnel towards a shop and making sales. M: What would be a go-to for potential clients who would like to create a new brand to be sold through Printful and create their content marketing?R: You have to build an audience. I don't have many examples nor experience, but many successful examples show that you can, for example, grow an Instagram account for dog-lovers and monetize it. You need a data base. You can also build hype by making an e-mail list, because you have to start somewhere, e-mail can't be your main channel. You can't send to some list, it has to be legal. The next channels are channels based on captured interest. From paid channels I can mention Google, which allows you to be found as an interesting author through searching. Then it's about whether the content on the website is enough. You create and all the elements mix together. It's hard to name one. Everything is organic game. It won't happen in one day. You'll see the results in the next few months. It's a long-term work.M: Printful grew very quickly, in just a couple of years. Was it a coincidence of showing up in the right time with the right product? Or was it the skill? I wonder if another company from a different category could duplicate what you did to grow five times or ten times quicker as they would otherwise?R: One mould that we have is “solve your problem”. Before Printful, there was Startup Vitamins, which still sells motivational posters. We needed them, because the offices of Draugiem.lv needed cool posters. Every cool office had those, so we needed them too. Didn't have them, so we designed some and started to sell. We did okay overall. We mostly printed posters, so we started to think about t-shirts and other things. I started searching for someone who could do it on demand, because we didn't know if they would sell. This niche turned out to be quite empty, so we decided to take it. Because again, what we're doing – we're solving our problem. The solution is so simple. In the end we printed our shirts, but it was planned out to be as fast and efficient as possible and with less costs.M: Do you feel a difference between the environments of Asia, Europe and North America when it comes to your clients?R: We haven't really delved into that. There might reasons why one is more successful and one isn't, but there aren't any cardinal differences. These reasons are mostly general. In japan, in order to switch your full-time job you need a special reason. In USA, side-hustling is very typical, you need to have an extra job to survive. You can drive an Uber or create an e-commerce shop. While in Germany and Scandinavia, you don't have such motivation. If you're happy with your job, you just have a beer and rest in your free time. You have other reasons for using Printful. In Germany, you need trust badges on your website for them to believe you're legit. There are some specifics, but it's not mainstream and isn't affecting much. We adapt.M: When you talked about brand development and marketing, one of the ways to grow a brand is word-of-mouth. One of your clients has successfully built his business. I think you mentioned that your tagline is “be your own boss”. This one successful person tells it to someone else, who also finds courage to try. For a company as big as yours, is such word-of-mouth still an important channel and tool?R: 100% yes! We might be big in Latvia, but the niche we can fill is still very small. How many e-commerce people in the world would sell printed goods and know about Printful? Not many. So this requires a constant drive. Social media stars rise every day nowadays, and they have an audience that can be reached more easily than ever, therefore it is important. The best approach is to be good at what you do. There's a guy who did a built-in kitchen for me. I have recommended him to at least 7 people, just because I'm satisfied with his job. If someone has a need, I will recommend him. And so it continues. It's the same for a company. It just happens in a bigger scale. When there's a chance to make a recommendation and someone has had good experience with you, he will recommend you, because it's something new he hasn't seen before. They become brand ambassadors. You don't pay them, you can only motivate them to do this more.M: This big trend of “creative economy” goes hand in hand with what you are doing with building an audience. MrBeast just launched his chocolate brand, which is super successful. He has built an enormous audience on YouTube, he launches one product after another. He has a chocolate or snack company. When you look at this category and also what you're doing with personalization and enabling people to be their own boss, do you see how this category develops and how big is the potential?R: That's one of the reasons why us too are developing and growing. Building an audience nowadays is much easier than it was twenty years ago. You can use the thing you have created – video, music, design –to captivate this person who wants to be associated with you, and, brutally speaking, you can monetize it. The ultimate goal is business. You create an audience and monetize it. One of my favourite examples recently are musicians. Musicians inspire passion in people. You follow them. If you like the music, you go to concerts and are ready to spend money. There are a lot of music bands, any one of them can start offering their merch.M: You've experienced an amazing and quick growth during the last five years. Do you have a vision for the following five years?R: We spend such a big part of life working. But in the end you work in order to be able to rest and live. The one thing on my plan is that I need more vacation days. If you work so much, you need time for resting, enjoy the fruits of your labour, spend time with family. There is still a lot of potential in Printful for development so you don't get bored. At some point I will address that too. M: What helped you to overcome the desire to do everything by yourself? I think that a lot of practical people are stuck in this bottleneck and are not ready to release the control.R: For example, if you have to send an e-mail, we agree on a period for doing it. Let's say, I will do it by Friday, but we agree that you will send me the contents by Thursday. If you are aware of the time period when it will happen and get this information, then you don't have to worry whether everything will be done on time. You just get a message that this is done. This has to be agreed upon. Then you can be sure that this person will check in with you that the text is ready, and on Friday you can confirm that everything is done. There have been occasions when I start writing e-mails and then have to edit this and that. When you start to delegate, the thing that you're afraid of is that something won't be done at all or in the quality you want. You just have to introduce these middle points. And any of these points can have a deadline. This way you can free your mind, because the computer will notify you at the right time. And you do the same thing with your team. You just write things down, you don't try to keep 10 things in mind. You say, this is our structure, these are the tasks, and this is the next step. By this time you have to do the following. If not, then you can start to micro-manage something else. That's where the trust comes from, just go through the game rules.M: Thank you.R: Cool, thank you.Raitis Puriņšhttps://www.linkedin.com/in/raitispurins/?originalSubdomain=lvhttps://www.printful.com/Subscribe to Asketic Podcast on:Spotify:https://open.spotify.com/show/73QSMYK46NHoHCytJYYmPZ?si=Mw4ZLISUSoueh9Es1pCLUgApple Podcast:https://podcasts.apple.com/lv/podcast/asketic-podcast/id1496922775YouTube:https://www.youtube.com/channel/UCQdekksSROS4PCxRV7aqT3QGoogle Podcasts:https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy50cmFuc2lzdG9yLmZtL2Fza2V0aWMtcG9kY2FzdA--Asketic design & branding:Instagram: https://www.instagram.com/asketicstudio/LinkedIn: https://www.linkedin.com/company/asketic/WWW: http://asketic.com/

Pat Mayo & Skylar Hoke discuss their favorite 2022 Dell Match Play DraftKings picks along with their favorite values for the week. Mayo previews the course, debates the best roster construction for the week and explains which players are best suited for DFS guaranteed prize pool (GPP) tournaments. PME DK LINK: https://bit.ly/22MPPMEDKLL Get 20% OFF @manscaped + Free Shipping with promo code MAYO at MANSCAPED.com! #ad #manscapedpod Play in the season long Fantasy Golf Contest at FanTeam for Corales. Use Code “MMN” at deposit to get a FREE DFS ticket into the MASTERS 20K GPP: Bracket Challenge: https://fanteam.blog/2022/03/20/wgc-matchplay-bracket-challenge-league/ IN USA: https://bit.ly/FanTeamMMNUSA REST OF WORLD: https://bit.ly/FanTeamMMN Mayo's Full Bracket Picks: https://www.instagram.com/p/CbYDjV8pO99/ Get 20% All DK Tools/Stat Engine: https://www.fantasynational.com/mayo Join Mayo Media Newsletter: https://mayomedia.substack.com/people/32468255-mayo-media Sub to the Mayo Media Network: https://bit.ly/YTMMN SHOW INDEX 00:00 Intro 1:28 Phil Mickelson OUT of Masters 3:21 Match Play DraftKings Strategy 19:03 10K 25:50 9K 28:27 DP World Your Qatar Masters Picks 34:18 8K 37:14 7K 51:23 6K 1:01:56 Weakest Pods 1:05:21 Strongest Pods

Pat Mayo and Geoff Fienberg preview the course and run through the odds while making their 2022 WGC Dell Match Play Picks. The guys give their fantasy golf picks, provide their one and done strategy for the event from Austin CC. PME DK LINK: https://bit.ly/22MPPMEDKLL Play in the season long Fantasy Golf Contest at FanTeam starting at THE PLAYERS. Use Code “MMN” at deposit to get a FREE DFS ticket when you enter the season long contest: Bracket Challenge: https://fanteam.blog/2022/03/20/wgc-matchplay-bracket-challenge-league/ IN USA: https://bit.ly/FanTeamMMNUSA REST OF WORLD: https://bit.ly/FanTeamMMN Mayo's Full Bracket Picks: https://www.instagram.com/p/CbYDjV8pO99/ Get 20% All DK Tools/Stat Engine: https://www.fantasynational.com/mayo Join Mayo Media Newsletter: https://mayomedia.substack.com/people/32468255-mayo-media Sub to the Mayo Media Network: https://bit.ly/YTMMN SHOW INDEX 00:00 Intro 2:43 Valspar Recap 4:51 Match Play 12:21 GROUP 1 19:07 GROUP 16 25:44 GROUP 8 30:43 GROUP 9 38:13 GROUP 4 41:03 GROUP 13 46:41 GROUP 5 49:29 GROUP 12 52:29 GROUP 2 59:57 GROUP 15 1:01:35 GROUP 7 1:03:06 GROUP 10 1:08:35 GROUP 3 1:12:22 GROUP 14 1:18:26 GROUP 6 1:20:24 GROUP 11 1:23:16 Bracket Picks 1:27:22 Quick Picks + ONE AND DONE

In questo audio il prezioso incontro con Vanni Cuoghi artista Adriana Albini biochimica.L'intervista con Vanni Cuoghi e Adriana Albini è in Contemporaneamente a cura di Mariantonietta Firmani il podcast pensato per Artribune.In Contemporaneamente podcast trovate incontri tematici con autorevoli interpreti del contemporaneo tra arte e scienza, letteratura, storia, filosofia, architettura, cinema e molto altro. Per approfondire questioni auliche ma anche cogenti e futuribili. Dialoghi straniati per accedere a nuove letture e possibili consapevolezze dei meccanismi correnti: tra locale e globale, tra individuo e società, tra pensiero maschile e pensiero femminile, per costruire una visione ampia, profonda ed oggettiva della realtà. Vanni Cuoghi e Adriana Albini ci raccontano di arte e scienza, dove l'essere e il fare coincidono. Di risultati eccellenti cui si arriva attraverso strade ampie e contorte, strettamente calato nel tempo in cui vive. Arte e scienza sono ambiti professionali altamente specializzati e rigorosi, fondati su intuito di ricerca. Ci raccontano di necessità delle relazioni, nutraceutica, nutrigenetica, nutrigenomica, tra bellezza e gioielli. E molto altro.ASCOLTA L'INTERVISTA!BREVI CENNI BIOGRAFICI DEGLI AUTORIVanni Cuoghi, artista dall'ottobre del 2015 è titolare della cattedra di Pittura presso l'Accademia Aldo Galli di Como.Ha partecipato a numerose biennali in Italia e all'estero, tra cui: Biennale di San Pietroburgo (2008), Biennale di Praga (2009). 54° Biennale di Venezia, Corderie dell'Arsenale, Padiglione Italia (2011), Biennale Italia-Cina (2012) e 56° Biennale di Venezia, Collateral Italia Docet (2015). Sue opere esposte in fiere internazionali come: Frieze (Londra), MiArt (Milano), Artefiera (Bologna), Scope (New York), Off (Bruxelles), Daegu Artfair (Corea), KIAF Seoul (Corea), Bank (Hong Kong). È presente in molte mostre collettive in prestigiose location pubbliche come: Palazzo Reale di Milano (2007 ), Haidian Exhibition Center di Pechino (2008). Liu Haisu Museum di Shangai (2008), Museo d'Arte Contemporanea di Permm, in Russia (2010), Castello Sforzesco di Milano (2012). Fabbrica del Vapore di Milano (2015), Vestfossen Kunstlaboratorium Museum in Norvegia (2018). Tra le mostre personali pubbliche si ricordano nel 2011 “Novus Malleus Maleficarum”, presso San Pietro in Atrio e Pinacoteca di Palazzo Volpi a Como.Nel 2013, “Aion" presso i Musei Civici Cremaschi a Crema, nel 2016 “Da Cielo a Terra” al Museo Ebraico di Bologna. Ed ancora nel 2017 “The Invisible Sun”, presso il Museo Francesco Messina a Milano. Nel 2012, su commissione di Costa Crociere, ha realizzato otto grandi dipinti per la nave Costa Fascinosa e nel 2014 sei per Costa Diadema. Le ultime mostre personali: nel maggio 2019 inaugura “The eye of the Storm”, una mostra personale presso la Rossi-Martino Gallery a Hong Kong. In ottobre inaugura la personale “Esuli pensieri” presso la Fondazione Balestra a Longiano (FC). A luglio del 2020 inaugura la mostra personale “Apnea”, a cura di Elisabetta Sgarbi presso le Argenterie nella Villa Reale di Monza. Nel 2021 inaugura la mostra personale “Submariner” al Civico Acquario di Milano, a cura di Nicoletta Castellaneta e Ivan Quaroni. Adriana Albini biochimica, docente e scrittrice italiana, unica donna italiana nella lista BBC 100 Women of 2020. Prima donna italiana eletta nel Board of Directors dell'American Association for Cancer Research.L'intensa attività scientifica è affiancata dalle passione per la scrittura che la porterà a pubblicare diversi romanzi. Appassionata di scherma è medaglia d'argento al campionato europeo del 2015 e bronzo ai Campionati del mondo per veterani 2018. Laurea in chimica organica nel 1979 all'università di Genova, dal 1988 è stata responsbabile di Laboratorio all'Istituto Scientifico Tumori di Genova, (ora San Martino) dove resterà fino al 2006 quando ne era vice-direttrice e direttrice di dipartimento. Specializzazione biochimica all'Istituto Max Plank, di Monaco di Baviera, e Scientist all'National Institute of Health a Bethesda USA fino al 1988, quando è rientrata in Italia. Nel 1985 mette a punto un modello di “metastasi in provetta” usato in tutto il mondo per facilità d'uso e basso costo, anche per lo studio dell'angiogenesi.Dal 2006 dirige laboratori di ricerca biomedica a Milano, Reggio Emilia e dal 2015 dirige un laboratorio di ricerca all'IRCCS MultiMedica ed è Direttore Scientifico di Fondazione MultiMedica Onlus di Milano. Inoltre insegna al Corso di Medicina in Englishall'Università Bicocca di Milano.. Ha diretto o coordinato laboratori di ricerca e gruppi di lavoro. È stata Presidente di società e Gruppi di studio: Comitato Tecnico Scientifico di O.N.Da (Osservatorio Nazionale sulla salute della Donna). Società Italiana di Cancerologia (SIC). Società Internazionale per lo Studio della Metastasi, Metastasis Research Society (MRS). Componente del Direttivo dell'American Association for Cancer Research. E molti altri. È titolare di 14 brevetti per nuove strategie terapeutiche contro il cancro.Conduce diversi studi sulla tossicità per il sistema cardiovascolare di farmaci antineoplastici e sul contributo alla progressione dei tumori, da parte delle cellule infiammatorie.Ha contribuito all'identificazione di un una nuova popolazione di cellule natural killer (NK), nei tumori solidi. Studia gli aspetti molecolari di componenti della dieta alimentare per la creazione di un programma di prevenzione delle neoplasie. Come immunologa ha lavorato su HIV e Covid-19. Svolge ricerca nell'ambito oncologico, in particolare sul microambiente tumorale e angiogenesi, sulla prevenzione farmacologica con derivati alimentari; le sue ricerche hanno evidenziato nelle acque di vegetazione dell'olio di oliva e nelle alghe principi attivi per la lotta contro il cancro; ha coordinato inoltre ricerche sui principi anticancerogeni del luppolo, nella ricerca “La birra e le sue proprietà nutraceutiche” su multimedica.it. e molti altri.Impegnata nella divulgazione Iscritta all'albo dei giornalisti è direttore editoriale della rivista online Cancerworld. Invitata in diversi programmi televisivi RAI tra cui Elisir e Geo. È componente delle redazioni di riviste scientifiche: Journal of the National Cancer Institute, Carcinogenesis, Molecular Cancer Therapeutics, Clinical & Experimental Metastasis, Pathology Oncology Research. Autrice di oltre 300 articoli scientifici, e diversi romanzi tra i cui La danza delle cellule immortali, 2008. In USA si sensibilizza al tema del gender gap e entra a far parte della associazione Women in Cancer Research curando corsi di formazione volti ad insegnare alle donne a farsi strada mettendo a frutto capacità e merito. Ha ideato e è presidente di TIWS (Top Italian Women Scientists), il club delle scienziate italiane più citate in campo biomedico. Tra i molti premi e riconoscimenti: Premio EUWIIN (Network Europeo Donne Inventrici ed Innovatrici nel 2015, Ambasciatrice di Genova nel mondo, BBC 100 women 2020.

Pat Mayo and Tyler Tamboline discuss their favorite 2022 PLAYERS Championship Bets, DraftKings picks, debate the best roster construction for the week and project ownership for DFS guaranteed prize pool (GPP) tournaments while taking viewer questions LIVE. PME DK LINK: https://bit.ly/22PLAYERSDKPME Play in the season long Fantasy Golf Contest at FanTeam starting at THE PLAYERS. Use Code “MMN” at deposit to get a FREE DFS ticket when you enter the season long contest: IN USA: https://bit.ly/FanTeamMMNUSA REST OF WORLD: https://bit.ly/FanTeamMMN Get 20% All DK Tools/Stat Engine: https://www.fantasynational.com/mayo Join Mayo Media Newsletter: https://mayomedia.substack.com/people/32468255-mayo-media Sub to the Mayo Media Network: https://bit.ly/YTMMN SHOW INDEX 00:00 Intro 1:44 Player News 3:54 Weather 10:59 Final Bets 16:06 DraftKings Ownership & Pivot Plays 37:09 Season Long 41:12 Chat Replay

Pat Mayo and Rick Gehman make their 2022 PLAYERS Championship DraftKings Picks previewing each playing in the field for the 2022 PLAYERS Championship. PME DK LINK: https://bit.ly/22PLAYERSDKPME Play in the season long Fantasy Golf Contest at FanTeam starting at THE PLAYERS. Use Code “MMN” at deposit to get a FREE DFS ticket when you enter the season long contest: IN USA: https://bit.ly/FanTeamMMNUSA REST OF WORLD: https://bit.ly/FanTeamMMN Get 20% All DK Tools/Stat Engine: https://www.fantasynational.com/mayo Join Mayo Media Newsletter: https://mayomedia.substack.com/people/32468255-mayo-media Sub to the Mayo Media Network: https://bit.ly/YTMMN Show Index 00:00 Intro/Giveaways 2:22 Jon Rahm 4:17 Rory 5:43 Morikawa 9:12 Justin Thomas 11:47 Viktor Hovland 14:52 Patrick Cantlay 17:31 Dustin Johnson 19:31 Xander 21:22 Hideki 23:52 Cam Smith 26:18 Scheffler 28:46 Jordan Spieth 31:13 Will Zalatoris 32:42 Berger 35:48 Louis 37:35 Brooks 39:13 Finau 42:17 Niemann 43:16 Sungjae 44:49 Adam Scott 45:52 Horschel 47:21 Lowry 49:08 Sam Burns 50:42 Hatton 52:41 Matt Fitzpatrick 54:55 Ancer 56:57 Webb 1:00:02 Homa 1:00:52 Leishman 1:01:54 Day 1:03:34 Henley 1:05:48 Casey 1:07:11 Sergio 1:08:02 Woodland 1:10:28 Fleetwood 1:11:11 Conners/Tringale 1:12:43 SI WOO KIM 1:13:42 Rose/Poulter 1:14:03 Kokrak 1:14:57 Reed 1:16:03 7000-7200 1:18:53 6500-7000 1:23:12 6500 & Lower

Pat Mayo and Geoff Fienberg preview the course and run through the odds while making their 2022 PLAYERS Championship Picks. The guys give their fantasy golf picks, provide their one and done strategy for the event from TPC Sawgrass. PME DK LINK: https://bit.ly/22PLAYERSDKPME Play in the season long Fantasy Golf Contest at FanTeam starting at THE PLAYERS. Use Code “MMN” at deposit to get a FREE DFS ticket when you enter the season long contest: IN USA: https://bit.ly/FanTeamMMNUSA REST OF WORLD: https://bit.ly/FanTeamMMN Get 20% All DK Tools/Stat Engine: https://www.fantasynational.com/mayo Join Mayo Media Newsletter: https://mayomedia.substack.com/people/32468255-mayo-media Sub to the Mayo Media Network: https://bit.ly/YTMMN SHOW INDEX 00:00 Intro 1:13 Bay Hill Recap 6:09 Strategy/Weather 10:43 Rory Comments/PLAYERS Coverage 21:19 ANDERCURSED 24:58 Brooks/DJ 32:14 Favorites 53:49 30-60 1:09:47 60-100 1:20:06 Long Shots 1:34:33 Quick Picks 1:37:41 One and Done

Biden's overhaul of Day Care?? WHAT? Day Care??? Build Back Better PASSES! More social spending and Climate regulations. So..less freedom! Got it! How does a trans, pro-pedophilia professor get a job at a Virginia University? Can you cross a bridge in a snow storm without massive spending? Gun ownership caused Rittenhouse case! Not a joke! Doctor's told by government to speak in “woke” language and ban certain prescriptions? IN USA? Winsome Sears is a rock star and a threat to the Left. (SO FUN) Is it still a vaccine if you need a booster? Did smallpox, polio, and chickenpox need a booster? Christian florist pays gay couple $5000 for denial of service. Conform and agree with us or suffer!

1 de octubre de 2021: IN ORBE TERRARUM: Biden contra ‘Americam Primum’ est. In USA 21,570 homicidia in 2020 sunt. In Aequatoria 116 rei mortui sunt. In Germania SPD vicit. In Russia trucidatio armis igniferis in universitate fuit. IN MEXICO: Alius ‘campus ad homines exterminandos’ inveniunt. Infans’O (id est Baby’O) speluncam igniunt. De casu Ayotzinapa. Posperitas Argentaria foederationis salaria persolvet. Mexici nativitas bicentenaria celebrant. De scientiae cultoribus casu. De nova ‘Heoidum Via’. De proximus tumultus pro vita e pro mulieribus. De 4.75% ratio creditorum.

Ilona Europa interview with polish / Hollywood actress MONIKA EKIERT. Monika is a Polish-French actress based between Los Angeles, Paris and Warsaw. She acts in English, French, Polish, Russian. Monika has been a lead actress in many polish and French TV shows and films. She was also the face of international fashion campaigns, working with famous brand names such as Giorgio Armani, L'Oréal Paris, Schwarzkopf, Redken, and many others. In USA, she has appeared in TV series, films, and theatre. Her role of 'The Girl' in "The Seven Year Itch", a role first played by Marilyn Monroe, brought her huge recognition. https://www.imdb.com/name/nm4861354/ actress reel: https://www.youtube.com/watch?v=62sxjVILfnE https://www.youtube.com/watch?v=UdRxltiZyE4

Photo: Marijuana leaf, sand sculpture contest, Canonchet Beach, Rhode Island @Batchelorshow The fresh growth of Christina Lake cannabis in the burgeoning THC and CBD oils marketplace. Joel Dumaresq, CEO & Director, Christina Lake Cannabis, British Columbia, Canada. IN USA trading symbol: C-L-C-F-F   In Canada trading symbol: C-L-C https://christinalakecannabis.com https://christinalakecannabis.com/wp-content/uploads/2021/05/CLC_Investor-Presentation_May-2021.pdf June 29, 2021 in Press Releases Christina Lake Cannabis Increases Average THC Concentration of Distillate Oils to 90.4% June 15, 2021 in Press Releases To Start the 2021 Growing Season, Christina Lake Cannabis Begins Transferring Over 45,000 Plants from the Greenhouse to the Field May 19, 2021 in Press Releases Christina Lake Cannabis Provides Q2 2021 Update Including R&D Milestones, Personnel Expansion, and Field Preparation for Upcoming Growing Season Christina Lake sits in the heart of two intersecting valleys in British Columbia, Canada. The unique geographic positioning creates a fertile delta and is one of the hottest parts of Canada making it one of the most desirable locations in North America for an outdoor cultivator. The location provides several benefits: Low Elevation At 500m above sea level, our valley is one of the lowest in the Kootenay Boundary region and as such, it lends itself to an extended growing season that typically spans up to 8 months of the year. Consistent Breezes We receive a consistent breeze from the southern-facing valley that aids in the structural development of our plants as well as their respiration cycles and pest control. Low Precipitation With a low average rainfall of 500mm, 54% of which takes place over the winter, our outdoor crops are less susceptible to water damage, mildew and rot. Ample Sunshine Thanks to the characteristics of our latitudinal valley, our location is exposed to a prolonged abundance of full-spectrum sunshine. Protective Valleys Nestled in a lush private setting, our 32-acre starting property is protected from the influences of outside industries.

Comedian & Podcaster Nikki Glaser joins the gang to gossip about going from growing up in St Louis to living with her parents as an adult again in St Louis. This episode is a whirlwind of an adventure, covering her dramatic teenage years to living life with an eating disorder - Nikki as always, holds nothing back. *Warning: todays episode features a long discussion on eating disorders. If you or someone you know is struggling or looking for assistance, please reach out. In Canada: https://nedic.ca/In USA: https://www.nationaleatingdisorders.org/International: https://www.worldeatingdisordersday.org/home/find-help/Remember hope & help are always available. Watch FULL episodes here: https://www.youtube.com/darcymichaelcomedyFollow Nikki on twitter: https://twitter.com/NikkiGlaserFollow Nikki on instagram: https://www.instagram.com/nikkiglaser/Follow us on Instagram: https://www.instagram.com/highschoolsucked/Follow us on Facebook:https://www.facebook.com/HighSchoolSuckedFor more Darcy & Jane click here: https://beacons.page/highschoolsuckedpodcastAs always, please rate, review & subscribe.xoxoDarcy & ToetoestoesJane See acast.com/privacy for privacy and opt-out information.

Wochenausblick: Rekorde bei Indizes und globale Mindeststeuer. Inflationssorgen haben die Märkte nicht arg belastet. In USA und Europa gingen die Kurse weiter nach oben. Der DAX konnte vergangenen Freitag sogar ein neues Rekordhoch markieren. Doch wie geht es nun weiter? Neues vom US-Markt und FED Die US-Arbeitsmarktdaten am vergangenen Freitag fielen nicht so stark wie erwartet aus. Davon könnten die Märkte jedoch profitieren. Durch die Hoffnung auf eine weitere stärkere Konjunkturerholung. Neues gab es auch von der US-Notenbank FED. Unternehmensanleihen und ETFs auf Unternehmensanleihen, welche in der Corona Pandemie erworben wurden, sollen bis Jahresende wieder verkauft werden. Deren Verkäufe sollen demnächst beginnen und bis Jahresende abgeschlossen sein. Im Vergleich zu den 120 Milliarden Dollar die monatlich für den Kauf von Staatsanleihen und Hypothekenpapieren aufgewendet werden ist der Betrag der gekauften Unternehmensanleihen sowieso eher gering. Kommt die globale Mindeststeuer? Die G7-Staaten waren ebenfalls aktiv. So soll es zukünftig eine globale Mindeststeuer von 15 Prozent für multinationale Konzerne geben. Für dieses Vorhaben müssen jedoch noch die OECD-Staaten, sowie die G20 Staaten zustimmen. Diese beinhalten auch Indien und China. Steueroasen wie Irland sind noch nicht begeistert. Da dies für die dort ansässigen US-Tech Konzerne höhere Steuern bedeuten würde. Zukünftiges Ziel der Politik: Es ist nicht mehr der Standort eines Unternehmens entscheidend. Sondern wo man seine Umsätze erzielt. Dies könnte dann auch deutsche Firmen treffen. Was kommt diese Woche auf uns zu? Hier sollte man die EZB-Zinssitzung am Donnerstag im Blick behalten. Eine Änderung der Geld Politik wird zwar nicht erwartet. Man sollte allerdings darauf achten was EZB-Präsidentin Christine Lagarde zu Konjunktur und Inflation zu sagen hat. Wichtige Wirtschaftsdaten aus den USA werden ebenfalls am Donnerstag veröffentlicht. Dein Tom Volz Trading Podcast & Zypern Auswandern Erfahrungen - Traden lernen mit einer Trading Ausbildung: https://tom-volz.com - Zum kostenlosen Beratungsgespräch: https://4rex-impulse.com/termin - Forex Broker Erfahrungen: https://tom-volz.com/forex-broker-erfahrungen-mit-fxglobe

Buone notizie per chi usa Google Home e magari ha un iPhone e quindi un'abbonamento ad Apple Music: in diversi paesi del mondo, tra cui Inghilterra, Germania e Francia, arriva la compatibilità tra Apple Music e gli smart speaker di Google. Per ora, però, non Italia, ma la novità dovrebbe essere dietro l'angolo.Gli utenti TIM potrebbero avere 100 gb gratis per 3 mesi: nella puntata di oggi vi racconto come fare.Billboard e Google fanno la classifica dei brani più canticchiati dell'anno. (In USA).Arrivano molte novità per i Google Pixel.

questa sera collegamento con la svizzera per i referendum etici, a Jesolo con assessore Perazzolo. Computer e privacy con Luciano Barbato. In USA con Malaguti per le presidenziali, non mancheranno le gustose ricette di San Martino di Lucia da Perugia. Buon Viaggio !! --- Support this podcast: https://anchor.fm/radio-nostra/support

Progetto a guida italiana. In Usa stop a test anticorpo Lilly

On this episode I interviewed Pastor Brian Stewart from Bloomington, IN USA about how he has implemented personal discipleship in his local church. I hope it's a blessing to you! For questions or comments you can reach us at generalorderfour@gmail.com or on twitter https://twitter.com/GeneralOrder4Music for this podcast provided by:Inspiring Teaser by Rafael KruxLink: https://filmmusic.io/song/5672-inspiring-teaser-License: http://creativecommons.org/licenses/by/4.0/

Reasons to Investigate Selling Internationally on Amazon - The opportunity - intro Amazon stats 2019 Amazon GMV 2019 worldwide was 280.5  Billion USD All of Amazon outside USA: Was 87B USD GMV in 2019 (31% of total) Amazon International selling summit: Global Empires Summit - Hosted by Kevin Sanderson My presentation for Summit: Overview of some lessons from the British Empire - the 4 horsemen - - and the “Merchant Mindset” BASH - and Merchant Skills that you need…. Why consider Amazon selling internationally? Reason 1: Additional Revenue - USA is about ⅔ of total - So even on average, you could add another ⅓ or so to sales by being fully diversified Reason 2: one of the easiest ways to expand - Identifying a market is hard - Getting a quality, differentiated product is really hard - Doing so profitably even harder! - Expanding once you've done all that EVEN in an era of more bureacracy is easier - Mostly because you can outsource the bureaucracy (tactical) but you CAN'T really outsource great sourcing (strategic) Reason 3: Profits/low competition - Fewer competitors in some places. Barriers to entry. - Inertia - Language barrier. EU Japan - Cultural barrier. Japan - VAT/Sales tax etc. barriers. EU. Japan etc - Strong currency EUR/DE - Wealthy consumers (EUR/DE) Reason for Amazon Selling Internationally: Diversifying Risk Reason 4: Currency risk - Diversifying risk 1 - Fluctuations - GBP to USD - Currency being punished - GBP! - EUR to USD tight range last few years Reason 5: COVID Risk Diversification -  Diversifying risk 2 - Demand shock - US helicopter money coming to end - UK furlough coming to end - UK GDP sank 20% in Q2 2020! - USA only 10% - Supply shock - Fr. And IT FCs shutdown height of COVID spring 2020 - US FC - US FC shutdowns to come? Reason 6: Amazon Suspension Risk - Diversifying Risk 3 - Reduce single-Amazon marketplace dependence - Individual countries can change regulations and lead to suspended listings - Eg Hazmat in Germany for client account - In USA, same exact product selling, no issues - An entire marketplace Amazon account can be suspended while others remain open Reason 7: Cashflow/Working Capital trick - MOQs - profit per unit - Stock turn (cashflow) - WC - function of profit and stock turn Cost-Benefit analysis  Upside (Benefit) assessment - Possible upside - Probability - Downside assessment (Cost) - How bad it could be - Possibility 3 Amazon overseas expansion opportunities - low hanging fruit Canada for US based sellers - Physically close so can affordably send stock - Straightforward. Helpful customs agents in Govt. - Speak English For UK sellers: Germany is a huge market Bigger than say Italy But similar costs/time to comply with VAT registration - All things being equal, better value Etc etc For all sellers - Japan - About same size as U.K. market GMV - 2 weeks shipping time to China. This is huge for cashflow!! - Only 10% sales tax on import cf 20% VAT into U.K. or EU - no research tools. Most sellers stay out. Again huge. Next steps Get informed about international Amazon Global Empires Summit - Hosted by Kevin Sanderson My presentation for Summit: Overview of some lessons from the British Empire - the 4 horsemen - - and the “Merchant Mindset” BASH - and Merchant Skills that you need…. Upcoming Interviews on 10K Collective podcast about Amazon International Selling Simply VAT about VAT in general, EU in particular and Brexit on 10K Collective Brexit - selling into OR from inside the UK Sales Tax update (selling in USA) Get expert help to start selling on Amazon abroad - Tax specialists - Freight forwarder (internationally) - Cultural expert (Esp for Japan) - General strategic guidance (coach)

HauntingLIVE! Podcast is a weekly Paranormal Podcast broadcasting LIVE Paranormal investigations with guest Jackie Dennison, host of the TV Show Rescue Mediums! On this Podcast we welcome to the show Jackie Dennison from the TV Show Rescue Mediums and part owner of feathers academy with proprietor of feathers academy in the UK! Jackie Dennison is a Clairvoyant Medium of International Status, with appearances in England on BBC TV, ITV, DMAX, CBS Reality, CBS Drama & Paranormal TV. Recently in the UK with Lime Productions for Channel 4 'My Psychic Life'. In USA on WE Network. In Germany on Pro7TV. She is however mostly known for Canada's successful TV Show 'Rescue Mediums'

Borse europee e asiatiche in rallentamento oggi.Il Nasdaq e il CSI 300 cinese continuano a salire.In USA i contagi di Covid19 salgono a 3 Milioni. ING Bank ci fornisce 3 scenari possibili sull'andamento economico per il 2020 e 2021 per l'Europa, l'USA e la Cina.Perchè nonostante la basse domanda l'ORO continua a salire ?

Smart working: In Usa dal 14 al 60%, una società amerciana su 5 sta elargendo contributi per acquistare attrezzature e arredi per rendere più confortevole il lavoro da casa. Succederà anche da noi in Italia? Potrebbe essere un'opportunità anche per l'Italia e per il Sud del Paese, ma c'è ancora molto da fare per abbattere le resistenze in atto. Ne abbiamo discusso con l'economista Nicolò Andreula, che nel libro Flow Generation ha raccontato il movimento dei nomadi digitali, che cresce e che sceglie di lavorare in mobilità e per obiettivi (dal minuto 2'06”).I cambiamenti culturali in azienda incidono su uno switch obbligatorio da parte degli imprenditori e dei manager, che dovrebbero assumere più fiducia e meno controllo. Roberto Lorusso, imprenditore di lungo corso, ha scritto “Umiltà, l'unico sostantivo della leadership” e ci racconta questo nuovo paradigma (da 5'30”).Il networking è un'attività necessaria sia dal punto di vista sociale ma anche in ottica di employability. Quando cerchiamo lavoro o scegliamo di cambiarlo, però, ci rivolgiamo a parenti e amici stretti, ignorando o sottovalutando quelli che si definiscono “legami deboli”, spesso determinanti, come ci spiega la nostra supercoach Pina Sabatino (da 12'00”)Buon ascolto! Photo - Model: @Austindistel https://www.instagram.com/austindistel/ Photographer: @breeandstephen https://www.instagram.com/breeandstephen/

In this episode we'll get straight into the concept of micro-investing and how it can help you save more money. In USA use: https://www.acorns.com/ ; in Australia use: https://raizinvest.com.au/ . You can't go wrong with these apps, they're super easy to use and you don't need to know anything about investing, finance of technology! --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app --- Send in a voice message: https://anchor.fm/joinmeforcoffee/message Support this podcast: https://anchor.fm/joinmeforcoffee/support

eCommerce and Corona Virus  Global Wired Advisors are experienced M & A Advisors for digitally native enterprise E-Commerce and Coronavirus with Jason Somerville of Global Wired Advisors Supply side effects of Coronavirus Started in China - supply chain effect A lot of ecommerce sellers and businesses had stocked up on inventory going into CNY - which mitigated supply chain issues As it spread into EU and USA it became a broader issue Demand side effects of Coronavirus As effects more acute, ecommerce has been affected Quarantine or stay at home order, that’s when bigger picture effects really started. Ecommerce has tended to be affected uniquely compared to others Public Capital markets effects of lockdown Mid march - stock market fell a lot. Business activity ground to a halt Except “essential” businesses Rotating from Virus discussion to post virus discussion. Ecommerce and Corona Virus   When people forced to stay home, many buy goods online. Many other businesses eg travel, airlines, restaurants, local stores been effectively shut off from economic activity for over a month. A lot of businesses that sell consumer goods that are “non essential” A number of clients march sales 4X Q4 in 2019 Supply side challenges for eCommerce and Amazon sellers It’s more an inventory management exercise to fulfil demand Amazon FBA issues Limit inbound Deprioritise non essentials Recession for eCommerce due to Coronavirus Most e-commerce businesses don’t have the downward trend. It’s more like a hockey stick! Within bigger picture, there is a big downward push in sales and economic activity. It’s not so much a V, it’s like a backwards checkmark. So in the short term, the left side of the V is There is a dramatic bounce say 50% of the depth of the left side Then you enter into recovery period The shape of that will be driven by How long the shutdown lasts Every week matters The longer it goes, the longer it takes to come back It won’t be a 1-month bounce back to the usual economy Government stimulus prog’s will also change it How effective How big Eg Federal Reserve etc. has tried hard but they’re inefficient, ham handed. Don’t always work the way they are supposed to work. It’s not just how many $, it’s about how they are delivered. ecommerce and Coronavirus short term -short term shift to online shopping Market share shifts from traditional to online This benefits a lot of ecomm business What to expect for ecommerce after Coronavirus -in the economic recovery stickiness is the key! This is bringing a lot of new customers to online shopping It’s bringing those who were online already, into categories they would still purchase in a retail outlet How sticky is that once economy starts to open up? It won’t be 100% stickiness but it may be 30-40% of that demand stays around for the long term Next factor - consumers damaged in downturn Discretionary items usually  go down in a recession Luxury good or high end (premium) these categories tend to go down first and sharpest Then you move into a new consumer behaviour model The changes in behaviour are correlated to depth and breadth of downturn How to shore up the value of your ecommerce business as an asset? Bucket 1 -  if your ecommerce sales have reduced seriously during lockdown Try to access as much liquidity as you possibly can In USA, a number of progs allow smaller progs to access liquidity for the businesses The investment in the future you make now will pay dividends Because This event is likely to affect consumer behaviour for the long term Ecommerce businesses are a lot more attractive as an asset than historically Get smart about stock management If you’re in a cat that you feel will take off after crisis, be ready!

eCommerce and Corona Virus  Global Wired Advisors are experienced M & A Advisors for digitally native enterprise E-Commerce and Coronavirus with Jason Somerville of Global Wired Advisors Supply side effects of Coronavirus Started in China - supply chain effect A lot of ecommerce sellers and businesses had stocked up on inventory going into CNY - which mitigated supply chain issues As it spread into EU and USA it became a broader issue Demand side effects of Coronavirus As effects more acute, ecommerce has been affected Quarantine or stay at home order, that's when bigger picture effects really started. Ecommerce has tended to be affected uniquely compared to others Public Capital markets effects of lockdown Mid march - stock market fell a lot. Business activity ground to a halt Except “essential” businesses Rotating from Virus discussion to post virus discussion. Ecommerce and Corona Virus   When people forced to stay home, many buy goods online. Many other businesses eg travel, airlines, restaurants, local stores been effectively shut off from economic activity for over a month. A lot of businesses that sell consumer goods that are “non essential” A number of clients march sales 4X Q4 in 2019 Supply side challenges for eCommerce and Amazon sellers It's more an inventory management exercise to fulfil demand Amazon FBA issues Limit inbound Deprioritise non essentials Recession for eCommerce due to Coronavirus Most e-commerce businesses don't have the downward trend. It's more like a hockey stick! Within bigger picture, there is a big downward push in sales and economic activity. It's not so much a V, it's like a backwards checkmark. So in the short term, the left side of the V is There is a dramatic bounce say 50% of the depth of the left side Then you enter into recovery period The shape of that will be driven by How long the shutdown lasts Every week matters The longer it goes, the longer it takes to come back It won't be a 1-month bounce back to the usual economy Government stimulus prog's will also change it How effective How big Eg Federal Reserve etc. has tried hard but they're inefficient, ham handed. Don't always work the way they are supposed to work. It's not just how many $, it's about how they are delivered. ecommerce and Coronavirus short term -short term shift to online shopping Market share shifts from traditional to online This benefits a lot of ecomm business What to expect for ecommerce after Coronavirus -in the economic recovery stickiness is the key! This is bringing a lot of new customers to online shopping It's bringing those who were online already, into categories they would still purchase in a retail outlet How sticky is that once economy starts to open up? It won't be 100% stickiness but it may be 30-40% of that demand stays around for the long term Next factor - consumers damaged in downturn Discretionary items usually  go down in a recession Luxury good or high end (premium) these categories tend to go down first and sharpest Then you move into a new consumer behaviour model The changes in behaviour are correlated to depth and breadth of downturn How to shore up the value of your ecommerce business as an asset? Bucket 1 -  if your ecommerce sales have reduced seriously during lockdown Try to access as much liquidity as you possibly can In USA, a number of progs allow smaller progs to access liquidity for the businesses The investment in the future you make now will pay dividends Because This event is likely to affect consumer behaviour for the long term Ecommerce businesses are a lot more attractive as an asset than historically Get smart about stock management If you're in a cat that you feel will take off after crisis, be ready!

Hi Guys! I’m Coach Cris and I am an online health and life coach, motivational speaker and international real estate broker associate. I help empower individuals by helping them transform in mind, body and spirit into the best version of themselves! I also provide income and leadership opportunities to real estate agents In USA, Canada, Australia & UK looking to expand their business. I also have the pleasure of being able to assist in creating income opportunities for individuals who are interested in starting there own business as a health coach and help others! I am available for coaching and real estate needs! - Coach Cris - Vixen Workouts Insta: @vixenworkout IG @fitbrokercris Facebook. @fitbrokercris86 Email: fitbrokercris24@gmail.com Interested in being a health coach and earning income: https://form.jotform.com/fitbrokercris/becomeacoach Interested in getting results and being a client: lose Weight, gain muscle or have more energy https://form.jotform.com/fitbrokercris/evaluation Join my 21 Day Body Transformation Challenge https://form.jotform.com/fitbrokercris/21bodysoul - Colton Trout - IG: https://www.instagram.com/ttdtlf/ FB: https://www.facebook.com/ttdcolton FB GROUP: https://www.facebook.com/groups/332683347615233/ JOIN THE CREW: https://purchasingpositivity.clickfunnels.com/optin-form1584879642957?fbclid=IwAR0dhG3dJZfxRzL724gYfYYgXxgitpFw_sQj5MTA7O6A3MTNr7T0anRhKSI

In USA and elsewhere in the world now feeling the sting of the deadly COVID-19 virus that some poor unfortunate and most probably innocent people in Wuhan, Hubei Province China unleashed on the world, there is growing apprehension that what is unknown about the pandemic continues to out- pace any true understanding of the virus. Amidst latest reports that possibly a virus lab located just three miles from that wet market where the Chinese Communist Party claims the COVID-19 Pandemic originated from bats, may have unleashed the virus is just too horrible to imagine but the story appeared this week in The Washington Times. As the world experiences one thing “Made in China” that we all could have done without, COVID-19 has caused pain, suffering and death everywhere. But now in USA where spread of the coronavirus is reportedly worse than anywhere else, the land of plenty is indeed just that as the government is sending the equivalent of USD$3400 to every family of four in the biggest cash giveaway in history. By contrast in Kenya where the coronavirus disease has also struck, and where a great many workers have already been sent home without pay, the pandemic has impacted people’s ability to provide the necessities of life, including food to eat. “The economic consequences of the COVID-19 Nairobi shutdown. especially for the people to whom we provide medical care and care in our homes, are completely incalculable,” Lufthansa Cargo Captain Fokko Doyen who founded Cargo Human Care the greatest charity in our industry told me. --- Support this podcast: https://anchor.fm/geoffrey-arend/support

L'epidemia da Covid-19 sta colpendo anche il settore commerciale della cannabis. In Italia sono circa 700 i negozi temporaneamente chiusi mentre gli effetti dei primi provvedimenti sono visibili anche in Spagna ed Olanda. Nel primo caso i cannabis social club hanno cessato le attività mentre i coffee shop olandesi, presi d'assalto fino a domenica, sono ora chiusi. Viene implementato il servizio di consegna a domicilio. In USA incetta di marijuana ricreativa prima delle possibili chiusure e garanzia di rifornimento per i malati. In Canada aumento dell'80% delle vendite in attesa dei primi provvedimenti di chiusura. IMPORTANTE: in trasmissione parliamo anche di altro...

L'epidemia da Covid-19 sta colpendo anche il settore commerciale della cannabis. In Italia sono circa 700 i negozi temporaneamente chiusi mentre gli effetti dei primi provvedimenti sono visibili anche in Spagna ed Olanda. Nel primo caso i cannabis social club hanno cessato le attività mentre i coffee shop olandesi, presi d'assalto fino a domenica, sono ora chiusi. Viene implementato il servizio di consegna a domicilio. In USA incetta di marijuana ricreativa prima delle possibili chiusure e garanzia di rifornimento per i malati. In Canada aumento dell'80% delle vendite in attesa dei primi provvedimenti di chiusura. IMPORTANTE: in trasmissione parliamo anche di altro...

In USA si inizia a parlare di crisi e di recessione a causa del Coronavirus? Ci sono davvero possibilità?SCOPRI DI PIÙ SUL MIO MONDO E SEGUIMI SUI SOCIAL: https://stefanomongardi.com/start-here

מסכת זבחים ד:ב – ד:ה Calendar for Cheshvan: https://bit.ly/2NrkaSt For the start of Seder Kodshim, we are delighted to announce our new collaboration with Mishna Sdura from Koren Publishers! Mishna Sdura have laid out the mishnayos in a clear format, designed for easy reading and learning. We have personally benefited greatly from the Mishna Sdura edition. Please see their Haskomos from Ha’agon R’ Chaim Kanievsky below. For a limited time, Mishna Sdura are offering all Time4Mishna subscribers a 20% discount on all mishnayos books and booklets with their easy-to-read Kav Naki commentary and/ or Ba’artenura commentary. For orders of a few books or more - email Koren directly orders@korenpub.com and the salesman will give you a discount, depending on the order. In USA - enter a discount code at checkout TIME4MISHNA - 20% discount IN GB - these stores have the Mishna Sdura or can easily order it (prices fixed by the stores): Additionally, they are allowing to use copies of their books in the Time4Mishna program for Masechtos Zevachim, Menachos and Chullin! Please let us know how you find them learning with them. Time4Mishna is always looking to grow in quantity and in quality! As we approach a new Seder, it is now the best time for new participants to subscribe so please be sure to tell your family and friends to sign up today! Any feedback you could give us at this time on how to improve the program would be most appreciated. Mazal Tov and Hatzlocha with Seder Kodshim! Please check out our brand-new App: iOS: https://apple.co/2SBYJyA Android: https://bit.ly/2VumbiV For our previous shiurim and summary sheets, visit our website: https://www.time4torah.org. Time4Torah is a member of the JFT family organisations. Have a question on one of the mishnayos? Contact us at: time4mishna@gmail.com, or whatsapp: +447552628361. You can support Time4Mishna at: https://www.paypal.me/JewishFuturesTrust Want to sponsor a whole masechta? https://time4torah.org/dedication/

מסכת זבחים ג:ד – ד:אש Calendar for Cheshvan: https://bit.ly/2NrkaSt For the start of Seder Kodshim, we are delighted to announce our new collaboration with Mishna Sdura from Koren Publishers! Mishna Sdura have laid out the mishnayos in a clear format, designed for easy reading and learning. We have personally benefited greatly from the Mishna Sdura edition. Please see their Haskomos from Ha’agon R’ Chaim Kanievsky below. For a limited time, Mishna Sdura are offering all Time4Mishna subscribers a 20% discount on all mishnayos books and booklets with their easy-to-read Kav Naki commentary and/ or Ba’artenura commentary. For orders of a few books or more - email Koren directly orders@korenpub.com and the salesman will give you a discount, depending on the order. In USA - enter a discount code at checkout TIME4MISHNA - 20% discount IN GB - these stores have the Mishna Sdura or can easily order it (prices fixed by the stores): Additionally, they are allowing to use copies of their books in the Time4Mishna program for Masechtos Zevachim, Menachos and Chullin! Please let us know how you find them learning with them. Time4Mishna is always looking to grow in quantity and in quality! As we approach a new Seder, it is now the best time for new participants to subscribe so please be sure to tell your family and friends to sign up today! Any feedback you could give us at this time on how to improve the program would be most appreciated. Mazal Tov and Hatzlocha with Seder Kodshim! Please check out our brand-new App: iOS: https://apple.co/2SBYJyA Android: https://bit.ly/2VumbiV For our previous shiurim and summary sheets, visit our website: https://www.time4torah.org. Time4Torah is a member of the JFT family organisations. Have a question on one of the mishnayos? Contact us at: time4mishna@gmail.com, or whatsapp: +447552628361. You can support Time4Mishna at: https://www.paypal.me/JewishFuturesTrust Want to sponsor a whole masechta? https://time4torah.org/dedication/

מסכת זבחים ב:ה – ג:ג Calendar for Cheshvan: https://bit.ly/2NrkaSt For the start of Seder Kodshim, we are delighted to announce our new collaboration with Mishna Sdura from Koren Publishers! Mishna Sdura have laid out the mishnayos in a clear format, designed for easy reading and learning. We have personally benefited greatly from the Mishna Sdura edition. Please see their Haskomos from Ha’agon R’ Chaim Kanievsky below. For a limited time, Mishna Sdura are offering all Time4Mishna subscribers a 20% discount on all mishnayos books and booklets with their easy-to-read Kav Naki commentary and/ or Ba’artenura commentary. For orders of a few books or more - email Koren directly orders@korenpub.com and the salesman will give you a discount, depending on the order. In USA - enter a discount code at checkout TIME4MISHNA - 20% discount IN GB - these stores have the Mishna Sdura or can easily order it (prices fixed by the stores): Additionally, they are allowing to use copies of their books in the Time4Mishna program for Masechtos Zevachim, Menachos and Chullin! Please let us know how you find them learning with them. Time4Mishna is always looking to grow in quantity and in quality! As we approach a new Seder, it is now the best time for new participants to subscribe so please be sure to tell your family and friends to sign up today! Any feedback you could give us at this time on how to improve the program would be most appreciated. Mazal Tov and Hatzlocha with Seder Kodshim! Please check out our brand-new App: iOS: https://apple.co/2SBYJyA Android: https://bit.ly/2VumbiV For our previous shiurim and summary sheets, visit our website: https://www.time4torah.org. Time4Torah is a member of the JFT family organisations. Have a question on one of the mishnayos? Contact us at: time4mishna@gmail.com, or whatsapp: +447552628361. You can support Time4Mishna at: https://www.paypal.me/JewishFuturesTrust Want to sponsor a whole masechta? https://time4torah.org/dedication/

מסכת זבחים ב:א – ב:ד Calendar for Cheshvan: https://bit.ly/2NrkaSt For the start of Seder Kodshim, we are delighted to announce our new collaboration with Mishna Sdura from Koren Publishers! Mishna Sdura have laid out the mishnayos in a clear format, designed for easy reading and learning. We have personally benefited greatly from the Mishna Sdura edition. Please see their Haskomos from Ha’agon R’ Chaim Kanievsky below. For a limited time, Mishna Sdura are offering all Time4Mishna subscribers a 20% discount on all mishnayos books and booklets with their easy-to-read Kav Naki commentary and/ or Ba’artenura commentary. For orders of a few books or more - email Koren directly orders@korenpub.com and the salesman will give you a discount, depending on the order. In USA - enter a discount code at checkout TIME4MISHNA - 20% discount IN GB - these stores have the Mishna Sdura or can easily order it (prices fixed by the stores): Additionally, they are allowing to use copies of their books in the Time4Mishna program for Masechtos Zevachim, Menachos and Chullin! Please let us know how you find them learning with them. Time4Mishna is always looking to grow in quantity and in quality! As we approach a new Seder, it is now the best time for new participants to subscribe so please be sure to tell your family and friends to sign up today! Any feedback you could give us at this time on how to improve the program would be most appreciated. Mazal Tov and Hatzlocha with Seder Kodshim! Please check out our brand-new App: iOS: https://apple.co/2SBYJyA Android: https://bit.ly/2VumbiV For our previous shiurim and summary sheets, visit our website: https://www.time4torah.org. Time4Torah is a member of the JFT family organisations. Have a question on one of the mishnayos? Contact us at: time4mishna@gmail.com, or whatsapp: +447552628361. You can support Time4Mishna at: https://www.paypal.me/JewishFuturesTrust Want to sponsor a whole masechta? https://time4torah.org/dedication/

Welcome to all our new members! For the start of Seder Kodshim, we are delighted to announce our new collaboration with Mishna Sdura from Koren Publishers! Mishna Sdura have laid out the mishnayos in a clear format, designed for easy reading and learning. We ourselves have personally benefited greatly from the Mishna Sdura style. Please see their Haskomos from Ha’agon R’ Chaim Kanievsky below. https://bit.ly/2Oq5yTG https://bit.ly/2KwVvLx https://bit.ly/34eYdwM For a limited time, Mishna Sdura are offering all Time4Mishna subscribers a 20% discount on all mishnayos books and booklets with their easy-to-read Kav Naki commentary and/ or Ba’artenura commentary. For orders of a few books or more - email Koren directly orders@korenpub.com and the salesman will give you a discount, depending on the order. In USA - enter a discount code at checkout TIME4MISHNA - 20% discount IN GB - these stores have the Mishna Sdura or can easily order it (prices fixed by the stores - be in touch for more details). Additionally, they are allowing to use copies of their books in the Time4Mishna program for Masechtos Zevachim, Menachos and Chullin! Please let us know how you find them learning with them. Time4Mishna is always looking to grow in quantity and in quality! As we approach a new Seder, it is now the best time for new participants to subscribe so please be sure to tell your family and friends to sign up today! https://bit.ly/2Ovk64i Any feedback you could give us at this time on how to improve the program would be most appreciated. Mazal Tov and Hatzlocha with Seder Kodshim! time4mishna@gmail.com

We would like to wish you a big Yosher Koach on finishing Seder Nezikin! For the upcoming start of Seder Kodshim, we are delighted to announce our new collaboration with Mishna Sdura from Koren Publishers! Mishna Sdura have laid out the mishnayos in a clear format, designed for easy reading and learning. We ourselves have personally benefited greatly from the Mishna Sdura style. Please see their Haskomos from Ha’agon R’ Chaim Kanievsky below. https://bit.ly/2Oq5yTG https://bit.ly/2KwVvLx https://bit.ly/34eYdwM For a limited time, Mishna Sdura are offering all Time4Mishna subscribers a 20% discount on all mishnayos books and booklets with their easy-to-read Kav Naki commentary and/ or Ba’artenura commentary. For orders of a few books or more - email Koren directly orders@korenpub.com and the salesman will give you a discount, depending on the order. In USA - enter a discount code at checkout TIME4MISHNA - 20% discount IN GB - these stores have the Mishna Sdura or can easily order it (prices fixed by the stores - be in touch for more details). Additionally, they are allowing to use copies of their books in the Time4Mishna program for Masechtos Zevachim, Menachos and Chullin! Please let us know how you find them learning with them. Time4Mishna is always looking to grow in quantity and in quality! As we approach a new Seder, it is now the best time for new participants to subscribe so please be sure to tell your family and friends to sign up today! https://bit.ly/2Ovk64i Any feedback you could give us at this time on how to improve the program would be most appreciated. Mazal Tov and Hatzlocha with Seder Kodshim! time4mishna@gmail.com

Was hat es mit der Opiatkrise in den USA auf sich und droht so etwas bei uns? — SONG / INTRO — In den USA sind in 2018 etwa 80.000 Menschen an einer Überdosis Drogen gestorben. In 36 Bundesstaaten verklagen mehr als 1.600 US-Städten Arzneimittelhersteller und Händler, um Milliarden Dollar für die Bekämpfung der Folgen der mit der Opioidsucht verbundenen Krise im Bereich der öffentlichen Gesundheit. Verordnung hat in D auch zugenommen. Droht auch eine Krise? Was sind Opiate, was Opioide?Stärkste Schmerzmittel Essentiell bei Tumorschmerz oder Herzinfarkt mit Todesangst Aus Opium = getrockneter Milchsaft des Schlafmohns Teilsynthese, Vollsynthese verschiedene Opiat-Rezeptoren Körpereigene = Opioide-Peptide Gleicher Rezeptor, gleiche Wirkung, gleiche Nebenwirkungen Wo wirken Opiate?Nicht Opioide Schmerzmittel vorwiegende am Ort der Schmerzentstehung Opioide vorwiegend auf die Weiterleitung des Schmerz im Rückenmark und Schmerzempfindung im Gehirn Welche Opiate gibt es? Welches ist das stärkste?Analgetische Potenz Morphin-Äquivalente 1 Fentanyl 120, Derivate bis zu 5000 und mehr Tilidin, Codein, Tramadol 0,1 Naloxon, Naltrexon 0 Antagonist Loperamid 0 https://de.wikipedia.org/wiki/Analgetische_Potenz  Gibt es Opiate die nicht süchtig machen?Nein Sucht eine Frage der Wirkstärke, Dosis und Zeitverlauf, v.a. schnell anflutend (kick) führt zum Missbrauch Selbst Tramadol hat Potential, daher Tropfen inzwischen BtM Tilidin wird mit Naloxon kombiniert Wer darf Opiate verschreiben?Nur Ärzte Rp: Einige auf normales Rezept BtM-Rp: die meisten auf BtM-Rezept mit 3 Kopien: Apotheke, Arzt, Bundes-Opiumstelle Nicht verkehrsfähig: Heroin, Morphin-Abkömmling, war 1897 Bayer Produkt, Bis in die dreißiger Jahre hinein verkaufte Bayer weltweit hochreines Marken-Heroin für viele Indikationen, einschließlich Husten, Depression, Asthma, Heroin-getränkte Tampons, 5% des Umsatzes, “heroische” Neuentwicklung, wurde ohne Daten als nicht-abhängigmachend vermarktet. Selbst die Gesunden hatten viel Spaß mit Heroin. Alpenclubs empfahlen ihren Mitgliedern, vor einer Tour ins Hochgebirge das Zeug zu schlucken, weil das die Atmung erleichtere. Entscheidend für die ausbleibende Sucht war die damals vorherrschende Art der Heroin-Aufnahme. Die Kranken schluckten nur wenige Milligramm - weniger als ein Zehntel dessen, was sich Fixer spritzen. Oral aufgenommen gelangt es nur langsam ins Gehirn. Einen Flash erlebten die damaligen Konsumenten nicht. Warum machen Opiate Verstopfung?Auch über µ-Rezeptoren Darmbewegung vermindert, Wasseraufnahme erhöht. Harter Stuhlgang der nur langsam ausgeschieden wird. Fast alle Patienten, teilweise belastender als der ursprüngliche Schmerz Mechanismus entspricht Loperamid bei der Reisediarrhoe, nur dieses wirkt nicht auf Nerven und Schmerz (Blut/Hirn-Schranke) Diese Nebenwirkung bleibt, immer Abführmittel mit verordnen Übelkeit, Erbrechen, Sedierung (Schlafanstoßend) Toleranz Wann machen Opiate abhängig?Wenn mehr als gebraucht, daher fester Zeitplan abhängig von der Wirkdauer Wenn nach “Bedarf” Wenn zu schnell abgesetzt Welche Risiken haben Opiate? Gibt es Gegenmittel? Hauptrisiko akute Überdosierung mit Atemlähmung  Gegenmittel Naloxon, auch zum Entzug Was in den USA passiert? In USA aggressive Vermarktung von Opioiden an Ärzte durch z.B. Johnson & Johnson und Purdue, erhöhten Opioidverordnung, danach erhöhten Mortalität aufgrund von Überdosierungen (Hadland et al. 2019). Anzeichen für eine Opioid-Epidemie in Australien und Kanada, aber nicht in Deutschland.  Chronischen Nichtkrebsschmerzen nur wenige profitieren. Sorgfältig Patienten selektieren. Mehrkomponentenschmerztherapien, hat Opioidepidemie in Deutschland verhindert (Häuser, Schug, and Furlan 2017). Opioide sind nicht die Ersttherapie für Patienten mit chronische nicht durch Krebs verursache Schmerzen (Busse et al. 2018). Oxycodon. zwölf Stunden Schmerzfreiheit, garantiert durch Über...

Torniamo sul documento dei 5 Stelle che, se approvato, disintegra la filiera della cannabis light mentre in Uruguay si pongono le basi per diventarne esportatore. In Messico inizia la discussione parlamentare per la legalizzazione, già attivata a Canberra (Australia). In USA passa alla Camera il Marijuana Banking Bill che, se approvato anche in Senato, permetterebbe alle transazioni riguardanti la marijuana di accedere al sistema bancario. In Italia? Tanto movimento nella corsa a depositare dei testi-bandiera sulla legalizzazione dimenticandosi che è già stata depositata alla Camera una legge di iniziativa popolare sottoscritta da 57.000 cittadini. Che la si mettesse in discussione!

Torniamo sul documento dei 5 Stelle che, se approvato, disintegra la filiera della cannabis light mentre in Uruguay si pongono le basi per diventarne esportatore. In Messico inizia la discussione parlamentare per la legalizzazione, già attivata a Canberra (Australia). In USA passa alla Camera il Marijuana Banking Bill che, se approvato anche in Senato, permetterebbe alle transazioni riguardanti la marijuana di accedere al sistema bancario. In Italia? Tanto movimento nella corsa a depositare dei testi-bandiera sulla legalizzazione dimenticandosi che è già stata depositata alla Camera una legge di iniziativa popolare sottoscritta da 57.000 cittadini. Che la si mettesse in discussione!

Almost any article on a pressing national crisis ends with some expert saying, "We must do something." By "we" they mean the national government. The fact is, most governments haven't solved problems for years. They only try to put out fires that they or their voters have set. In USA, the fire is Trump; in UK, it is Brexit. Most national problem-solving has ended, and Glenn Campbell argues that it won't be back. The only "we" that can still be effective is local, not national.

Ram Menen has seen many seasons come and go, spending more than two decades first as part of the launch team and then as top executive of Emirates SkyCargo where he led that organization to the top of the world. Today, happily retired in Luxembourg and Kuala Lumpur, Ram is a much sought after air cargo executive that readily shares his take on 2019 in an exclusive FlyingTalkers interview. Neel Jones Shah is a smart guy and a dreamer and doer. He is no shrinking violet either, but rather someone who is actively on the front lines of change, having moved rather easily from top management at the airlines into top management at the wunderkind bunch at Flexport where he serves as EVP and Global Head of Airfreight. Once upon a time, Neel as the head of Delta Cargo, led approximately 2,000 employees worldwide and oversaw over $1 Billion in freight & mail revenues. In USA, Bake Me A Wish, headquartered in New York City began in 2005, offering nationwide service for gourmet birthday cake delivery nationwide . During the past 14 plus years the company has grown to offer more and more of the finest bakery gifts available including gourmet cookies, brownies, cupcakes, pies and quiches. “There is no better way to celebrate a special occasion than to send a little indulgence from someone who cares,” said company founder Josh Kaye. --- Support this podcast: https://anchor.fm/geoffrey-arend/support

Welcome to Finance and Fury, The Furious Friday edition Continuing SDGs – today we are covering Economics or SDG 8 First, look at the economics of the UN itself – something never talked about Who pays for the UN – Member states - A complex formula - US pays most at 22%-28% of the UN's different budgets Aus - Regular budget for AUD - $86m (rough estimate) in 2016 - $58m USD – not too much But the official budget doesn’t include other donations – Gov agency voluntary contributions (specified or unspecified) – all revenues from government donors – Total was $747m p.a. USD ($1.1bn) – across 21 UN organisations A lot of money being shipped to UN when we have a desperate need to more infrastructure and helping create more liveable areas outside of Cities – Up from $601m in 2014 – massively increased - UN revenues massively increased – What does the UN spend money on? 2016, the organisation's total expenditures was nearly $50 billion, with the US financing about $10 billion, or one fifth, of that. Even with costs surging fourfold in the last 20 years – expenditures have been compounding at 7.8% p.a. since 1976 UN plans - Economic growth and decent work – SDG 8 Promote sustained, inclusive and sustainable economic growth, full and productive employment and decent work for all. World Pensions Council (WPC) development economists have argued that the twin considerations of long-term economic growth and infrastructure investment weren’t prioritized enough – Plan is growth through full employment on infrastructure projections 2020 Target - to reduce youth unemployment and operationalise a global strategy for youth employment. Implementing the Global Jobs Pact of the International Labour Organization is also mentioned. 2030 target - to establish policies for sustainable tourism that will create jobs. Strengthening domestic financial institutions and increasing Aid for Trade support for developing countries is considered essential to economic development (not for us though, but other nations). Implementing an Enhanced Integrated Framework for Trade-Related Technical Assistance to Least Developed Countries is their method for achieving sustainable economic development UN say that $5trn a year is needed – mobilise a lot more than currently being spent – essentially mass redistribution   At this economic model’s core - Global redistribution of GDP – push out lower-paying jobs to be outsourced by AI or by globalisation Built around David Ricardo's Comparative advantage theory from 1817 – Spent 4.5y doing Commerce – Finance also Economics – International Trade and Finance – Knew the right answers on the tests – That comparative advantage should benefit both parties if done right How the theory works – which argued that countries should specialise in the production of goods in which they have a relative advantage over other countries in production - promoting benefits of international trade Example – Back then a mutual trade benefit would be realised between China and the United Kingdom from China specialising in the production of porcelain and tea and the United Kingdom concentrating on machine parts. Makes sense right? In the 90s China for low wages in manufacturing/production and west for Service-based economy But what the theory doesn’t account for – Not 1817 – Capital (money) is easy to transfer across borders – Technology as well – With Capital comes technology (FDI) – China as an example – FDI and increase in tech – outproduce across board – but slowly wages rise in china – so do costs – so production leapfrogs to another country with lower wages – so previous country stagnates in wages and growth – then new country goes through the same cycle - so on – race to the bottom – takes a while – Has been happening since 1975 – Lima Accord – set the framework for the movement of capital and technology to developing nations – which are the labour cost in comparative countries Modern Robin Hood – But you are the rich when compared to the third world UN has engineered the decline of the Comparative Advantage efficiency – simply a beggar thy neighbour policy now that creates downward pressures on wages globally – Name of Globalism The offshoring of jobs has reduced Australian (USA, UK, other 1st world nations) manufacturing and industrial capability and associated innovation, research, development, supply chains, consumer purchasing power, and tax base of state and local governments – technology comes from engineering and not science (especially climate science) Comparative advantage Creates a Focus of Multi-national companies on short-term profits at the expense of these long-term costs – Effect of moving our economies to the developing world Currency and taxes come into this – Today Media calling tariffs a trade war - There is no trade war – simply the US trying to protect their industries by placing tariff barriers on the import of cheaper products from foreign countries The irony is half of the imports from China are imports from US companies – US at war with US companies – go figure Evident that our economies are in decline – GDP growth slowing as over decades our manufacturing/industrial/engineering capability has been transferred abroad. Our demise is what is fuelling countries like China - owes it faster than expected rise as a world power to the transfer of jobs, capital, technology, and business know-how to China Jobs have been declining for years in terms of value-added and pay – creates aggregate demand decline (lower GDP growth) Proof from listed companies using profits not for investment in new plant and equipment, but to buy back their own shares or make once-off dividend payments Economic growth comes from a rising labour force participation rate and engineering innovation – More people earning more money – better productivity than more money on top - Governments tried Aggregate demand model of redistribution (UBI proposed) – more likely Government work programs (infrastructure projects) – Gov projects force minimum wages – offer $15 in USA – employees have to now compete with gov – unfair as they are contributing through taxes to fund their own demise – What if the work isn’t worth $15 USA an hour? In USA – offer insurances and benefits – making it even harder for small businesses to complete But this wage capped and unaffordable –has to come from taxes – and would also be taxed – making it an inefficient redistribution – but does increase size and importance/reliance on Gov Perfect socialist world we would all get $100k p.a. for not working – but resources aren’t infinite As costs of labour increase in developing countries (i.e. china wage rises) – to maximise profits – wage regulations in developed countries further compound the decline in employment and wages Which is where it gets worse when combined with the implementation of recommended policies within the higher labour cost countries Decent work – the work that is funded by the Gov- limits free-market choices when Government competes – Almost like having a Communist Nation and fee market operating at the same time -   From the club of Rome – Watched their online lectures – available on the LinkedIn learning centres – not hiding it – just have to look Shorten the length of the work year and raise the retirement ages Redefine ‘paid work’ to cover those who care for others at home and Increase unemployment benefits Increase the taxation to redistribute profits – introduce death taxes Tax fossil energy to make low-carbon energy more competitive – higher prices (no different to tariffs) Shift taxes from employment to emissions and resource Increase death taxes to reduce inequality and philanthropy while boosting government income Expand the use of green stimulus packages by printing money or raising taxes to help governments respond to climate change and the need for redistribution Encourage unionization and restrict trade and business where necessary   With no employment or wage growth – where will growth come from? Same as last 30 years - Mostly debt – Some UN current donations from Governments – Also have infrastructure spending access from Supers, tax – next ep Mostly debt fuel growth through massive government infrastructure spending – employ people in the employment plans at higher than market wages with insurances and benefits (higher super counts) – all at additional costs to Gov budgets Plus more and more regulation – John Stossel did a great interview with entrepreneurs in Africa – Inequality they face is competition from the West through free stuff (can't compete with free) and Government regulations – which leads to corruption – only way to get things done is through bribes or having millions to get around regulations/paying the fines The whole of Economic growth in 21st century is expansion through Government spending and debt – cheap credit but consumer income has not kept pace and consumer debt expansion has reached its limits – at 120%   The core is to try and keep the debt-based economy going – IMF SDRs spending massive amounts of money on the next great social program – some referred to it as the great leap forward – create higher inflation again, then inflate the current debts away over time – also is the next step in a one-world currency – if they gain legitimacy and become the global reserve currency like China and Russia want Governments try to increase asset prices through printing money But this doesn’t increase production, as jobs and economic activity don’t exist anymore Just makes the property and other assets more expensive for us – while pushing up costs of living Next is to drive growth through reindustrialisation – global infrastructure works and climate change action – Growth driven by debt – FDR style – Great Society programs of mass Gov employment – at expense of population and companies paying for those wages – Gov spending comes form you or borrowing in your name Last next part is to merge Governments and companies – Fascism 101 – but only approved companies – create a completely controlled economy Through the consumption and production outlines in the circular economy Take away – Governments have proved to only be economic destruction houses – long history of getting it wrong and creating economic decline slowly over time with equilibrium policies – So why give them even more control and power over the economy and our lives? Other take away – Policies to fuel world GDP growth through more ‘beggar they neighbour’ policy – Take advantage through investing in Asian/developing markets and infrastructure companies – more on this next Friday   Thanks for listening – Next week – go through infrastructures and the inequality angle  If you want to get in contact, you can here.   UN Revenue by Gov data – https://www.unsystem.org/content/FS-D00-02 https://www.unsystem.org/content/FS-D03-01

In USA alone, according to a study, disengaged management costs the economy over $100 billion. If you own a business with employees this is a must listen to episode. If you work for a company but want more clarity for what type of leadership you work with, definitely listen to this episode. It might just save your career. Share this episode and leave a comment with a FIVE star review if you haven't done so already and if you haven't subscribed to this podcast yet go ahead and hit the Subscribe button. To connect or ask a question you can find Raphael on: Instagram: http://instagram.com/raphaelmavi Facebook: http://facebook.com/Raphaelmavi

✴️ In USA circola una bozza di legge che potrebbe bloccare LIBRA...✴️ IRAN pensa ad una crypto di stato...✴️ BAKKT: ce la faranno i nostri "eroi"..?✅Argomenti del giorno:

Unethical Chinese Amazon Black Hat Tactics with Kevin King Contents: Amazon Black hat in China - What Chinese sellers are learning Amazon's response to Black Hat Is it worth spending time worrying about Unethical black hat tactics in Amazon? Yes it is serious. Kevin likes to keep to white hat on Amazon. But he likes to know what’s Chinese Amazon sellers are doing. Amazon Black Hat training in Canton Kevin was speaking at the  MDS - Million dollar seller group with Brandon Young They were invited to an event. It’s a weekly meeting on Amazon black hat tactics- and there were 1300 people there! It was a Sunday meeting - and it was all about reviews. The following meeting completely new topic. Chinese Communist Party is involved with Amazon Black Hat Strategies They were in a side room with a promoter. Then Kevin heard a loudspeaker - the Communist Party turned up. If you have over 1000 people at a gathering, you’re required to ask the Communist Party. Being a good citizen - like a mini pep rally. In USA, they pledge allegiance; in UK, you might sing something! [not really! - ed.] Professional events for Amazon Black Hat There are 1300 people - nice room, 5 screens (like a big football match) - host is beautiful. The 5-6 speakers that spoke (in Chinese) were all about getting reviews with Amazon Black Hat tactics. These guys paid 30 RMB - $6-7 to come to the event The info was things that in the USA, Europe, you’d pay $5-10K to learn! Kevin and Brendon presented on  white -hat tactics - using Manychat (Brendon) and  postcards (Kevin). To check out the "Helium10 Elite" online mastermind (formerly "Illuminati Mastermind") lead by Kevin King and Manny Coates, go to https://pages.helium10.com/register-elite?crsh_reqid=374520  Chinese style product research The next day they did a special event for $300 each  About 60 people came. Brendon asked: how are you finding products? Their system was look on Jungle Scout to figure out what to sell - get it made - and then use Black hat techniques to get it launched.    Amazon Black hat tactics being taught in China How to get 2000 buyer accounts. How to get 2000 credit card numbers eg bank of America will give you 600 of them! They have the inside SOPs from Amazon. eg “Don’t leave a review within 14 days” However, most don’t do social media. Why Chinese sellers use Amazon black hat techniques One of the guys came over to the hotel - been in Wall Street Journal - spoke to a few of the guys. Kevin asked him point blank - How do we compete with Amazon black hat users in China? Why are they teaching black hat in China? The reason why is “because it’s super competitive in China. There are 1.4 B people here! Also we’re “communist capitalists” - if we see an opportunity to make money, we need to grab it. We’re not trying to build a brand. We don’t care about having 50 amazon accounts.  Also, we don’t know whether the Chinese gov’t will make it illegal or tax us a lot. “ In the US or UK, economies more democratic. The situation in China is different. Amazon Seller Black hat users - who is doing this? Most of the 1300 people at the event turned out to work for big companies - Kevin’s US friends say: Only about 60 companies in China  cause all the issues. There is one doing $1B sales. They have 3 floors of a building, with 1000 people per floor. They have people responsible for 5 products on Amazon; same products on eBay, 5 other guys. Also they work almost non-stop - “9X9X6” - 12 hours a day, 6 days a week (9 am -9pm) Work for $1000 a month! Launching product after product - don’t care if 4/5 fail. Amazon courting Chinese factories Amazon is courting Chinese sellers - lightning deals etc. Amazon is all about giving the customers the best price - that’s why they’re courting the Chinese so heavily. Marketplace plus - 40% of all active Amazon seller accounts are coming out of China.

In USA tutti i nodi stanno per venir al pettine: vi riassumiamo tutto velocemente su Hope, Beth, Thomas e i risvolti dark!

Heute erkläre ich Chris Anthony Sorour was Mezzanine Kapital ist, warum man es einsetzt und warum man es sehr schnell zurück zahlen sollte. Der Projektinitiator hat wenig bis gar kein Geld, die Bank möchte aber einen Eigenkapitalquote von 10-25%, hier ist Mezzanine Financing die Lösung. In USA nennt man die Geldverleiher auch treffend “Hard Money Lender”. Wenn es Euch gefallen hat bewertet uns bitte und gebt uns einen review. --- Send in a voice message: https://anchor.fm/alexanderkorte/message

John Haime is a Human Performance Coach who prepares performers to be their very best by helping them tap into the elusive 10% of their abilities that will elevate them to the top. This is something that anyone with a goal craves and John Haime knows how to get performers there. John closes the gap for performers in business, sports and the arts taking them from where they currently are to where they want to go. The best in the world trust John. They choose him because he doesn’t just talk and theorize about the world of high performance – he has lived it and lives in it everyday. He is a former Tournament Professional Golfer with professional wins. He has a best-selling book “You are a Contender” that is widely read by world-class athletes, coaches and business performers. He has worked around the globe for some of the world’s leading companies. Athlete clients include performers who regularly rank in the World Top 50 in their respective sports. John has the rare ability to work as seamlessly in the world of professional/high level sports as he does in the world of business/leadership or the performing arts. Clients all agree that John Haime cares about them as a performer and a person. Working with individuals or teams, John takes clients inside his world of high performance and provides insights and long-term solutions to help them build on core capabilities. He shares the fundamentals and a defined, proven, step by step process that he uses with the world’s best. The process features the very best elements from performance psychology, emotional intelligence, sport psychology, business planning, executive coaching and neuroscience. Clients learn what separates the average from the elite and how individuals and teams can maximize abilities. John is passionate about helping others prepare, think and perform like a world-class athlete. He coaches clients on how to tap into the 10% that makes 90% of the difference in daily performance. Along with a variety of professional accreditations, John has been mentored by some of the top industry practitioners in human performance and leadership. He is a life-long learner believing that what worked yesterday is often outdated today. He has researched, studied, investigated and used trial and error to help people perform at extraordinary levels. His only benchmark is measurable, sustainable results for valued New Edge Performance clients. He is a graduate of Purdue University, West Lafayette, IN USA. John lives in Ottawa, Canada with his wife and son.

Ritirarsi dal lavoro a 30 o 40 anni: possibile?In USA c'è un numero sempre crescente di Millennials che fa questa scelta,soprattutto in occasione di lavori altamente retribuiti ma molto stressantiMettono da parte il più possibile durante gli anni di lavoro e poi staccano,per dedicarsi a se stessi, agli altri, a cause sociali o culturali.E' il Movimento FIRE (financial independence, retire early), di cui parla il New York Timeshttps://www.nytimes.com/2018/09/01/style/fire-financial-independence-retire-early.html

Join us for Part 1 of the Mario Kart 64 and Double Dash tournament at the GameXchange in Noblesville, IN. Thanks to Cody, David, Ricky, Tristan, and Javon for appearing on this episode. GameXchange: 205 Sheridan Rd Noblesville, IN USA (317) 770-8121 https://www.facebook.com/GXCNI/ Patreon: https://www.patreon.com/asapodcasting Amazon Link to Help Fight Cystic Fibrosis: https://tinyurl.com/ASAPodcastingAmazon FB: https://www.facebook.com/groups/askyrimaddictpodcast/ Twitter: https://twitter.com/ASAPodKarting Email: asapodkarting@gmail.com Forum: ASAPodcasting.Proboards.com

A mere 1 percent of all youth athletes end up playing pro. What is the goal of youth sports for those other 99 percent? In this episode, John Haime discusses the real skills that kids can learn in the locker room and transfer to the board room. Bio John is a world-class Coach in the area of performance and one of the world’s leading authorities in Emotional Intelligence as it relates to performance in sport. He personally coaches leading professional and elite amateur athletes, corporate athletes and artists in a variety of performance areas. He is a sought after speaker by sports and corporate groups around the globe.  John has competed at the highest levels in sports performance. From 1985 to 1991, John successfully competed on international golf tours in Canada, Australia, Asia, South Africa and the United States. Along with several professional victories, career highlights include a career low 62 in a professional event in Melbourne, Australia. Before turning professional he was one of Canada’s top amateur and junior golfers. John has been published in leading business, leadership and sport publications. His highly anticipated first book, You Are a Contender! Build Emotional Muscle to Perform Better and Achieve More … in Business, Sports and Life was released in December 2009 by Morgan James (New York). You are a Contender! became a bestseller in the United States in mid-2010. The 2nd edition of the book was released in February 2016. Through New Edge Performance, John Haime works with some of the world’s leading professional and elite amateur athletes on mental/emotional high performance. He regularly works with World Top 50 athletes in a variety of sports. The “New Edge” athlete process (5 stages) (http://johnhaime.com/athletes/) helps athletes build a sustainable, dynamic platform for performance offering growth and independence for the athlete in sport and beyond the game. The robust program has the very best elements from performance psychology, sport psychology, executive coaching, business planning, emotional intelligence and neuroscience. It is the most complete, dynamic program a young athlete can experience. New Edge Performance and John Haime are consulting with athletes and global sport organizations (professional and amateur) in golf, tennis, hockey, basketball, swimming, soccer, track and field, baseball, football, volleyball, squash and equestrian. John has been chosen by a number of leading organizations as the program developer for their mindset modules. The most recent is for the Asian Institute of Sport – Asia’s leading elite athlete development organization. John lives in Ottawa, Canada with his wife and son. He is a graduate of Purdue University, West Lafayette, IN USA. Subscribe to the Way of Champions Podcast on iTunes   Show Notes 9:15 The most important quality of high-performance teams 14:30 John shares an easy athlete self-assessment process 21:15 Performance starts in the mind. This is where coaches should start 26:30 How can someone develop great psychosocial skills in sports? 32:15 Finding balance in the youth sports machine and social media mania 39:00 Why don’t athletes build the key skills to succeed in and beyond the game 46:15 Start with why 50:15 Best way to find John Haime 54:00 Closing thoughts   Get in Touch 12 Week Athlete Program: 12 Week Athlete Course John’s Book: You Are a Contender Download   If you are enjoying our podcast, please help us out and leave a review on iTunes. How to leave an iTunes rating or review for a podcast from your iPhone or iPad   Launch Apple’s Podcast app. Tap the Search tab. Enter the name Way of Champions. Tap the blue Search key at the bottom right. Tap the album art for the Way of Champions podcast. Tap the Reviews tab. Tap Write a Review at the bottom. Thanks so much, every review helps us to spread this message!

Non sono nuovo a queste tematiche, se mi segui, sai che ne ho parlato in passato.Sia nei canali in cui produco contenuti ma anche i gruppi social dove partecipo, uno su tutti quello di Libero Pensiero Immobiliare su Facebook.Dunque, veniamo a noi ed entriamo nel dettaglio...Che il mondo dell'immobiliare necessiti di un cambiamento, di uno svecchiamento, non è roba nuova... anzi, è praticamente roba trita e ritrita. Se ne parla e se ne riparla continuamente, si discute ferventemente, spesso si va a collidere e ci si manda a quel paese in maniera elegante.Dopo tutto questo polverone, un giorno sì e l'altro pure, secondo te si è ottenuto qualcosa? No.Le cose, nonostante a parole si esprima il concetto all'infinito, quasi alla noia, nella pratica sono ben diverse.La verità è che si rimane legati alle solite vecchie storie, attività, procedure, passaggi, tecniche che hanno le ore contate. E lo sai anche tu, te lo stanno dicendo tutti i GURU dell'immobiliare nazionali ed internazionali, non serve di certo un collega a dirtelo.Le tecniche che abbiamo sempre implementato, a partire dagli anni 80 e sviluppatisi poi, possono continuare a funzionare oggi e nei prossimi giorni, ma per quanto ancora produrranno risultati? Mesi, anni? Non decenni, fidati.Siamo davanti ad una rivoluzione imminente, nei prossimi 5 anni cambierà completamente il modo in cui si fa marketing, in tutti i settori.Il real estate non ne sarà escluso, noi agenti immobiliari non ne rimarremo esclusi.Allora, vuoi restare al palo o vuoi cambiare modo di lavorare? La scelta è ovviamente tua, per la tua agenzia, per il tuo business, per la tua famiglia.In USA, anche se non ti piacerà saperlo perché lo sai già, l'agente immobiliare fa marketing immobiliare ad altissimo livello da decenni."Blah blah blah... l'Italia è diversa, noi siamo agenti, non marketers... il cliente è abituato al vecchio sistema e non funzionerà... ho provato a fare una pagina Facebook ma è meglio il profilo... ho fatto il sito web e nessuno ci entra..."Sai, nonostante non dovrei fare questa sorta di "marchetta", lo faccio lo stesso perché a me ha aperto gli occhi.Nei mesi scorsi ho letto un libro di Michele Tampieri, illuminante per i contenuti che ci ho trovato dentro. Ho allora approfondito sull'argomento, ho trovato molte informazioni sul tema, aldilà di Michele che in Italia è uno dei principali esperti in materia, puoi trovare un sacco di roba... soprattutto se parli inglese, e ti consiglio in questo caso Russell Brunson.Comunque, il tema è il funnel marketing, ossia fare marketing con gli imbuti, processi canalizzati dove le persone vanno dove tu decidi che vadano, ne hai mai sentito parlare?Hai presente l'Ikea? Ecco, quello è un funnel... tu entri e segui un percorso guidato di acquisto!Sulla base di questo, ho deciso di intervistarlo e condividere con te quello che pensa in merito a questa rivoluzione del marketing.Allora, ti invito ad ascoltare/vedere la puntata, poi se ti interessa, approfondisci tu stesso e valuta cosa puoi fare da oggi per cambiare in meglio la tua agenzia immobiliare.Io ho già iniziato...

Non sono nuovo a queste tematiche, se mi segui, sai che ne ho parlato in passato.Sia nei canali in cui produco contenuti ma anche i gruppi social dove partecipo, uno su tutti quello di Libero Pensiero Immobiliare su Facebook.Dunque, veniamo a noi ed entriamo nel dettaglio...Che il mondo dell'immobiliare necessiti di un cambiamento, di uno svecchiamento, non è roba nuova... anzi, è praticamente roba trita e ritrita. Se ne parla e se ne riparla continuamente, si discute ferventemente, spesso si va a collidere e ci si manda a quel paese in maniera elegante.Dopo tutto questo polverone, un giorno sì e l'altro pure, secondo te si è ottenuto qualcosa? No.Le cose, nonostante a parole si esprima il concetto all'infinito, quasi alla noia, nella pratica sono ben diverse.La verità è che si rimane legati alle solite vecchie storie, attività, procedure, passaggi, tecniche che hanno le ore contate. E lo sai anche tu, te lo stanno dicendo tutti i GURU dell'immobiliare nazionali ed internazionali, non serve di certo un collega a dirtelo.Le tecniche che abbiamo sempre implementato, a partire dagli anni 80 e sviluppatisi poi, possono continuare a funzionare oggi e nei prossimi giorni, ma per quanto ancora produrranno risultati? Mesi, anni? Non decenni, fidati.Siamo davanti ad una rivoluzione imminente, nei prossimi 5 anni cambierà completamente il modo in cui si fa marketing, in tutti i settori.Il real estate non ne sarà escluso, noi agenti immobiliari non ne rimarremo esclusi.Allora, vuoi restare al palo o vuoi cambiare modo di lavorare? La scelta è ovviamente tua, per la tua agenzia, per il tuo business, per la tua famiglia.In USA, anche se non ti piacerà saperlo perché lo sai già, l'agente immobiliare fa marketing immobiliare ad altissimo livello da decenni."Blah blah blah... l'Italia è diversa, noi siamo agenti, non marketers... il cliente è abituato al vecchio sistema e non funzionerà... ho provato a fare una pagina Facebook ma è meglio il profilo... ho fatto il sito web e nessuno ci entra..."Sai, nonostante non dovrei fare questa sorta di "marchetta", lo faccio lo stesso perché a me ha aperto gli occhi.Nei mesi scorsi ho letto un libro di Michele Tampieri, illuminante per i contenuti che ci ho trovato dentro. Ho allora approfondito sull'argomento, ho trovato molte informazioni sul tema, aldilà di Michele che in Italia è uno dei principali esperti in materia, puoi trovare un sacco di roba... soprattutto se parli inglese, e ti consiglio in questo caso Russell Brunson.Comunque, il tema è il funnel marketing, ossia fare marketing con gli imbuti, processi canalizzati dove le persone vanno dove tu decidi che vadano, ne hai mai sentito parlare?Hai presente l'Ikea? Ecco, quello è un funnel... tu entri e segui un percorso guidato di acquisto!Sulla base di questo, ho deciso di intervistarlo e condividere con te quello che pensa in merito a questa rivoluzione del marketing.Allora, ti invito ad ascoltare/vedere la puntata, poi se ti interessa, approfondisci tu stesso e valuta cosa puoi fare da oggi per cambiare in meglio la tua agenzia immobiliare.Io ho già iniziato...

Views from the Pews to Amuse - our book that's quite good - click the link -In USA: http://amzn.to/2yC1A1tIn UK: http://amzn.to/2fMmG5DJust a brief update - we've put together this book of edgy, satirical and sometimes silly poems together with on point Bible verses - to buy it for your Kindle click on one of the links above. If you don't to, that's fine too, the videos and audio podcast remain absolutely free. But the book is good, honest. And so are Jelly Babies (not a sponsor). Subscribe https://www.youtube.com/channel/UCGwCncsQ8nl59ElDWQuKP7gFacebook https://www.facebook.com/goodnewsthismorning?ref=hlTwitter https://twitter.com/goodnewsthisPete's blog http://petertimothycooper.comPodcasts featuring Pete:Mark and Pete http://www.markandpete.comThe Good News Show http://www.tgnsuk.comDaily Devotional Preaching http://www.dailydevotionalpreaching.comGood News This Morning is:Personal updates from Pete, his family and Friends. comment on interesting, moving and humorous news and articles of the day from a Christian perspective.This channel is dedicated to presenting a sideways look at breaking Christian news and and fascinating features of theology. In these Christian videos, pastor Peter Cooper takes a look at Christian issues of the day, sometimes serious and sometimes whacky: its a Christian video blog.

Views from the Pews to Amuse - our book that's quite good - click the link - In USA: http://amzn.to/2yC1A1t In UK: http://amzn.to/2fMmG5D Just a brief update - we've put together this book of edgy, satirical and sometimes silly poems together with on point Bible verses - to buy it for your Kindle click on one of the links above. If you don't to, that's fine too, the videos and audio podcast remain absolutely free. But the book is good, honest. And so are Jelly Babies (not a sponsor). Subscribe https://www.youtube.com/channel/UCGwCncsQ8nl59ElDWQuKP7g Facebook https://www.facebook.com/goodnewsthismorning?ref=hl Twitter https://twitter.com/goodnewsthis Pete's blog http://petertimothycooper.com Podcasts featuring Pete: Mark and Pete http://www.markandpete.com The Good News Show http://www.tgnsuk.com Daily Devotional Preaching http://www.dailydevotionalpreaching.com Good News This Morning is: Personal updates from Pete, his family and Friends. comment on interesting, moving and humorous news and articles of the day from a Christian perspective.This channel is dedicated to presenting a sideways look at breaking Christian news and and fascinating features of theology. In these Christian videos, pastor Peter Cooper takes a look at Christian issues of the day, sometimes serious and sometimes whacky: its a Christian video blog.

This week on the show, we'll be talking to Petra about the NetBSD foundation, about how they operate and assist NetBSD behind the scenes. That plus lots of news This episode was brought to you by Headlines What is new on EC2 for FreeBSD 11.0-RELEASE (http://www.daemonology.net/blog/2016-10-03-FreeBSD-EC2-11-0-RELEASE.html) “FreeBSD 11.0-RELEASE is just around the corner, and it will be bringing a long list of new features and improvements — far too many for me to list here. I think there are some improvements in FreeBSD 11.0 which are particularly noteworthy for EC2 users.” “First, the EC2 Console Screenshot functionality now works with FreeBSD. This provides a "VGA" output as opposed to the traditional "serial port" which EC2 has exposed as "console output" for the past decade, and is useful largely because the "VGA" output becomes available immediately whereas the "serial port" output can lag by several minutes. This improvement is a simple configuration change — older releases didn't waste time writing to a non-serial console because it didn't go anywhere until Amazon added support on their side — and can be enabled on older FreeBSD releases by changing the line console="comconsole" to boot_multicons="YES" in /boot/loader.conf.” “The second notable change is support for EC2 "Enhanced Networking" using Intel 82599 hardware; on the C3, C4, R3, I2, D2, and M4 (excluding m4.16xlarge) families, this provides increased network throughput and reduced latency and jitter, since it allows FreeBSD to talk directly to the networking hardware rather than via a Xen paravirtual interface. Getting this working took much longer than I had hoped, but the final problem turned out not to be in FreeBSD at all — we were tickling an interrupt-routing bug in a version of Xen used in EC2. Unfortunately FreeBSD does not yet have support for the new "Elastic Network Adapter" enhanced networking used in P2 and X1 instance families and the m4.16xlarge instance type; I'm hoping that we'll have a driver for that before FreeBSD 11.1 arrives.” “The third notable change is an improvement in EC2 disk throughput. This comes thanks to enabling indirect segment I/Os in FreeBSD's blkfront driver; while the support was present in 10.3, I had it turned off by default due to performance anomalies on some EC2 instances. (Those EC2 performance problems have been resolved, and disk I/O performance in EC2 on FreeBSD 10.3 can now be safely improved by removing the line hw.xbd.xbdenableindirect="0" from /boot/loader.conf.)” “Finally, FreeBSD now supports all 128 CPUs in the x1.32xlarge instance type. This improvement comes thanks to two changes: The FreeBSD default kernel was modified in 2014 to support up to 256 CPUs (up from 64), but that resulted in a (fixed-size) section of preallocated memory being exhausted early in the boot process on systems with 92 or more CPUs; a few months ago I changed that value to tune automatically so that FreeBSD can now boot and not immediately panic with an out-of-the-box setup on such large systems.” “I think FreeBSD/EC2 users will be very happy with FreeBSD 11.0-RELEASE; but I'd like to end with an important reminder: No matter what you might see on FTP servers, in EC2, or available via freebsd-update, the new release has not been released until you see a GPG-signed email from the release engineer. This is not just a theoretical point: In my time as a FreeBSD developer I've seen multiple instances of last-minute release re-rolls happening due to problems being discovered very late, so the fact that you can see bits doesn't necessarily mean that they are ready to be downloaded. I hope you're looking forward to 11.0-RELEASE, but please be patient.” *** Upgrading Amazon EC2 instance from 10.3 to 11.0-PRERELEASE results in hang at boot (https://bugs.freebsd.org/bugzilla/show_bug.cgi?id=213196) As if to underscore that last point, a last minute bug was found on sunday night A user reported that they used freebsd-update to upgrade an EC2 instance from 10.3 to 11.0 and it started hanging during boot After some quick investigation by Colin, the problem was reproduced Since I had done a lot of work in the loader recently, I helped Colin build a version of the loader with a lot of the debugging enabled, and some more added to try to isolate where in the loader the freeze was happening Colin and I worked late into the night, but eventually found the read from disk that was causing the hang Unlike most of the other reads, that were going into the heap, this read was into a very low memory address, right near the 640kb border. This initially distracted us from the real cause of the problem With more debugging added, it was determined that the problem was in the GELIBoot code, when reading the last sector of each partition to determine if it is encrypted. In cases where the partition is not 4k aligned, and butts up against the end of the disk, the formula used could result in a read past the end of the disk The formula rounds the last sector byte address down to the nearest factor of 4096, then reads 4096 bytes. Then that buffer is examined to determine if the partition is encrypted. If it is a 512b sector drive, the metadata will be in the last 512 bytes of that 4096 byte buffer. However, if the partition is not 4k aligned, the rounding will produce a value that is less than 4096 bytes from the end of the disk, and attempting to read 4096 bytes, will read past the end of the disk Normally this isn't that big of a problem, the BIOS will just return an error. The loader will retry up to three times, then give up and move on, continuing to boot normally. Some BIOSes are buggy, and will initiate their own retries, and the combination might result in a stall of up to 30 seconds for each attempt to read past the end of the disk But it seems that Amazon EC2 instances, (and possibly other virtual instances), will just hang in this case. This bug has existed for 6 months, but was not caught because almost all installations are 4k aligned thanks to changes made to the installer over the last few years, and most hardware continues to boot with no sign of a problem Even the EC2 snapshot images of 11.0 do not have the problem, as they use a newer disk layout that is 4k aligned by default now. The problem only seems to happen when older disk images are upgraded The fix has been committed and will be merged the the branches over the next few days An Errata notice will be issues, and the fix will be available via freebsd-update It is recommended that EC2 users, and anyone who wants to be especially cautious, wait until this errata notice goes out before attempting to upgrade from FreeBSD 10.3 to 11.0 You can determine if your partitions are 4k aligned by running ‘gpart show'. If there is free space after your last partition, you won't have any issues. *** OpenBSD 6.0 Limited Edition CD set (signed by developers) (http://undeadly.org/cgi?action=article&sid=20160929230557&mode=expanded) The first one went for .$4,200.00 (http://www.ebay.com/itm/-/331985953783) + Looking for your piece of OpenBSD history? At the recent g2k16 hackathon in Cambridge UK, 40 OpenBSD developers put pen to paper and signed 5 copies of the new 6.0 release. + Each of these will be auctioned off on ebay, with the proceeds to benefit the OpenBSD foundation. + The first auction has already ended, and CD set went for a whopping $4200! + The next set only has 2 days left, and currently stands at $3000! (http://www.ebay.com/itm/-/331990536246) + Get your bids in soon, these are VERY unique, the odds of getting the same 40 developers in a room together and signing a new .0 release may make this a once-in-a-lifetime opportunity. + Additionally, if you are just starting your OpenBSD collection, here's a nice image to make you envious: A nice collection of OpenBSD CD Sets (http://i.imgur.com/OrE0Gsa.png) [What typing ^D really does on Unix ](https://utcc.utoronto.ca/~cks/space/blog/unix/TypingEOFEffects) + How often have you used a ^D to generate an EOF? Do you really know what that does? + Chris Siebenmann has posted a look at this on his blog, which might not be what you think “Typing ^D causes the tty driver to immediately finish a read().” He continues on: Normally doing a read() from a terminal is line-buffered inside the tty driver; your program only wakes up when the tty driver sees the newline, at which point you get back the full line. (Note that this buffering is distinct from anything that your language's IO system may be doing.) Typing ^D causes the tty driver to stop waiting for a newline and immediately return from the read() with however much of the line has been accumulated to date. If you haven't typed anything on the line yet, there is nothing accumulated and the read() will return 0 bytes, which is conveniently the signal for end of file. If you have typed something the program will get it; because it doesn't have a trailing newline, the program's own line-buffering may take over and keep read()ing to get the rest of the line. (Other programs will immediately process the partial line with no buffering; cat is one example of this.) Once you've typed ^D on a partial line, that portion of the line is immutable because it's already been given to the program. Most Unixes won't let you backspace over such partial lines; effectively they become output, not input. (Note that modern shells are not good examples of this, because they don't do line-buffered input; to support command line editing, they switch terminal input into an uninterpreted mode. So they get the raw ^D and can do whatever they want with it, and they can let you edit as much of the pending line as they want.) Fascinating stuff, and interesting to see behind the curtain at exactly what's going on with your programs buffering and tty driver interaction. Interview - Petra Zeidler - spz@netbsd.org (mailto:spz@netbsd.org) NetBSD Foundation *** News Roundup Running FreeBSD in Travis-CI Thanks to KQEmu (http://erouault.blogspot.com/2016/09/running-freebsd-in-travis-ci.html) Travis-CI is the most popular testing framework on Github, but it doesn't support any of the BSDs This didn't discourage Even Rouault, who managed to run FreeBSD in KQEMU on the Linux instances provided by Travis-CI “Travis-CI has a free offer for software having public repository at GitHub. Travis-CI provides cloud instances running Linux or Mac OS X. To increase portability tests of GDAL, I wondered if it was somehow possible to run another operating system with Travis-CI, for example FreeBSD. A search lead me to this question (https://github.com/travis-ci/travis-ci/issues/1818) in their bug tracker but the outcome seems to be that it is not possible, nor in their medium or long term plans.” “One idea that came quickly to mind was to use the QEMU machine emulator that can simulate full machines, of several hardware architectures.” They found an existing image of FreeBSD 9.2 and configured the Travis job to download it and fire it up in QEMU. “Here we go: ./configure && make ! That works, but 50 minutes later (the maximum length of a Travis-CI job), our job is killed with perhaps only 10% of the GDAL code base being compiled. The reason is that we used the pure software emulation mode of QEMU that involves on-the-fly disassembling of the code to be run and re-assembling.” Travis-CI runs in Google Compute Engine, which does not allow nested virtualization, so hardware virtualization is not an option to speed up QEMU “Here comes the time for good old memories and a bit of software archeology. QEMU was started by Fabrice Bellard. If you didn't know his name yet, F. Bellard created FFMPEG and QEMU, holds a world record for the number of decimals of Pi computed on a COTS PC, has ported QEMU in JavaScript to run the Linux kernel in your browser, devised BPG, a new compression based on HEVC, etc....” “At the time where his interest was focused on QEMU, he created KQemu, a kernel module (for Linux, Windows, FreeBSD hosts), that could significantly enhance QEMU performance when the guest and hosts are x86/x86_64 and does not require (nor use) hardware virtualization instructions.” “Running it on Travis-CI was successful too, with the compilation being done in 20 minutes, so probably half of the speed of bare metal, which is good enough.” “I could also have potentially tried VirtualBox because, as mentioned above, it supports software virtualization with acceleration. But that is only for 32 bit guests (and I didn't find a ready-made FreeBSD 32bit image that you can directly ssh into). For 64 bit guests, VirtualBox require hardware virtualization to be available in the host. To the best of my knowledge, KQemu is (was) the only solution to enable acceleration of 64 bit guests without hardware requirements.” It will be interesting to see if enough people do this hack, maybe Travis-CI will consider properly supporting FreeBSD *** OpenBSD EuroBSDcon 2016 Papers are online (https://www.openbsd.org/events.html) Slides from the OpenBSD talks at EuroBSDCon are online now Landry Breuil, Building packages on exotic architectures (https://rhaalovely.net/~landry/eurobsdcon2016/) Peter Hessler, Bidirectional Forwarding Detection (BFD) implementation and support in OpenBSD (https://www.openbsd.org/papers/eurobsdcon2016-bfd.pdf) Ingo Schwarze, Why and how you ought to keep multibyte character support simple (https://www.openbsd.org/papers/eurobsdcon2016-utf8.pdf) (roff/mm/gpresent source code (https://www.openbsd.org/papers/eurobsdcon2016-utf8.roff)) Stefan Sperling, OpenBSD meets 802.11n (https://www.openbsd.org/papers/eurobsdcon2016-openbsd-11n.pdf) Antoine Jacoutot, OpenBSD rc.d(8) (https://www.bsdfrog.org/pub/events/openbsd-rcd-EuroBSDcon2016.pdf) Marc Espie, Retrofitting privsep into dpb and pkg_add (https://www.openbsd.org/papers/eurobsdcon2016-privsep.pdf) Martin Pieuchot, Embracing the BSD routing table (https://www.openbsd.org/papers/eurobsdcon2016-embracingbsdrt.pdf) I am working to build a similar website for the FreeBSD project, but there is still a lot of work to do I also managed to find the slides from the keynotes: Opening Keynote: George Neville-Neil: Looking Backwards: The coming decades of BSD (https://papers.freebsd.org/2016/EuroBSDCon/LookingBackwards.pdf) Closing Keynote: Gert Döring: Internet Attacks, Self-Governance, and the Consequences (http://www.monobsd.com/files/16_ddos_and_consequences.pptx) *** VirtualBox Shared Folders on FreeBSD: progress report (https://kernelnomicon.org/?p=650) In the past month or so, VirtualBox in the FreeBSD ports tree got bumped to version 5, which while bringing new features, did cause a regression in Shared Folders. FreeBSD developer gonzo@ (Oleksandr Tymoshenko) has been tackling this issue in recent days and provides us with a look behind the curtain at the challenges involved. Specifically he started by implementing the various needed VOPs: “lookup, access, readdir, read, getattr, readlink, remove, rmdir, symlink, close, create, open, write.” He then continues with details about how complete this is: ““Kind of implemented” means that I was able to mount directory, traverse it, read file, calculate md5 sums and compare with host's md5sum, create/remove directories, unzip zip file, etc but I doubt it would survive stress-test. Locking is all wrong at the moment and read/write VOPs allocate buffers for every operation.” The bigger issue faced is with the rename VOP though: I hit a roadblock with rename VOP: it involves some non-trivial locking logic and also there is a problem with cached paths. VBox hypervisor operates on full paths so we cache them in vboxfs nodes, but if one of parent directories is renamed, all cached names should be modified accordingly. I am going to tackle these two problems once I have long enough stretch of time time sit and concentrate on task. + We wish him luck in getting those issues solved. I know quite a few of our users rely on shared folders as well. FreeBSD News Issue #1 (http://support.rossw.net/FreeBSD-Issue1.pdf) Issue #1 of FreeBSD News, from summer of 1997 Contains an article by Yahoo! co-founder David Filo about their early use of FreeBSD, on 100mhz Pentium machines with 64MB of ram Java Development Kit 1.0.2 ported to FreeBSD What is FreeBSD? Running the world's busiest FTP site (cdrom.com) on FreeBSD Xi Graphics announces the release of CDE Business Desktop, the first and only integrated desktop for FreeBSD, on AcceleratedX, a fully supported commercial grade X display server Get FreeBSD 2.2.2 Today! *** Beastie Bits Call for testing: newly MPSAFE nvme(4) (http://mail-index.netbsd.org/current-users/2016/09/21/msg030183.html) Thinking about starting a BUG in Indianapolis, IN USA (http://lists.dragonflybsd.org/pipermail/users/2016-September/313061.html) The cost of forsaking C: Why students still need to learn C (https://medium.com/bradfield-cs/the-cost-of-forsaking-c-113986438784#.o2m5gv8y7) OpenBSD (U)EFI bootloader howto (https://blog.jasper.la/openbsd-uefi-bootloader-howto/) Michael Lucas sets his eyes on OpenBSD's web stack for his next book (http://blather.michaelwlucas.com/archives/2780) LibreSSL 2.5.0 released (http://ftp.openbsd.org/pub/OpenBSD/LibreSSL/libressl-2.5.0-relnotes.txt) OPNsense 16.7.5 released (https://opnsense.org/opnsense-16-7-5-released/) Feedback/Questions Jonas - ZFS on DO (http://pastebin.com/XeJhK0AJ) Ricardo - OpenBSD Encrypted Disk (http://pastebin.com/Z9JRjcvb) WiskerTickle - Storage Benchmark (http://pastebin.com/XAD0UevP) Phil - Thanks (http://pastebin.com/N52JhYru) Luis - Misc Questions (http://pastebin.com/57qS0wrx) ***

MuggleNet interviews Stefan Coisson to discuss the Harry Potter TCG (Trading Card Game) tournament that is taking place at Gen Con 2015 in Indianapolis, IN USA. In this interview, we discuss the game's history and play as well as the tournament layout for Gen Con 2015. We are hoping to see a resurgence of this game from the early 2000's when it was first introduced. Thanks for listening!

The news has come out this week, Johnny Manziel will be the back-up qb starting week 1. In USA basketball news, D.Rose sat out the last 2 practices and will play tonight in am exhibition game. 2 Steelers running backs were cited for weed and driving impaired. Join the asylum with ya boys El-Boogie and T.Ro. Tell a friend, to tell a friend, to tell a whole bunch of girlfriends..........

Actresses Jessic St. Clair and Lennon Parham. In USA’s new comedy “Playing House,” Lennon Parham (“Best Friends Forever”) stars as Maggie Caruso, a woman who is determined to create a happy home for her baby, despite recently discovering her husband’s illicit online affair with a muscular German woman. In USA’s new comedy “Playing House,” Jessica St. Clair (“Best Friends Forever”) stars as Emma Crawford, a strong-willed, passionate and career driven woman who moves back to her small hometown to help her best friend, Maggie (Lennon Parham, “Best Friends Forever”), raise her first baby. St. Clair co-stars and co-created the series along with Parham.  Playing House premieres April 29 from 10 - 11pm (eastern) on the USA Network.

The new technology used to diagnose heart disease is amazing. We will explore if the time has come for you to take advantage of it. A couple of new studies indicate there's more than one reason to take Viagra. And if you're under 60 and suffer from atrial fibrillation, a new study shows there's something you may want to stop consuming. Dr. Tedd Mitchell is the medical director and a staff physician at Cooper Clinic in Dallas. Dr. Mitchell is double-boarded  in Internal Medicine and Sports Medicine. Dr. Mitchell is the contributing health editor and a weekly columnist for USA Weekend, a member of the President's Council on Physical Fitness and Sports, and co-author of Fit to Lead. Dr. Janet Tornelli is a staff physician at Cooper Clinic in Dallas. Dr. Tornelli is board certified in Internal Medicine and is a member of the Texas State Board of Medical Examiners.    References: Moderate Drinking Linked to A-Fib in Younger Patients http://www.internalmedicinenews.com/article/PIIS109786900770985X/fulltext   ED Drugs Tame Lower Urinary Tract Symptoms http://www.internalmedicinenews.com/article/PIIS1097869007709745/fulltext   CT Angiography Efficient for Initial Screening http://www.internalmedicinenews.com/article/PIIS1097869007709885/fulltext   The Devastating Effects Of Depression When It Accompanies A Chronic Disease http://www.medicalnewstoday.com/articles/81745.php   Youth Suicide Rate Rises 8% In USA, Biggest Climb In 15 Years http://www.medicalnewstoday.com/articles/81868.php   Heavy Drinking Hastens Deaths in Chronic Diseases http://www.internalmedicinenews.com/article/PIIS1097869007709800/fulltext   Sildenafil Citrate Therapy for Pulmonary Arterial Hypertension http://content.nejm.org/cgi/content/short/353/20/214