Podcasts about remicade

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Best podcasts about remicade

Latest podcast episodes about remicade

Empowered Patient Podcast
Using Anti-TNF Therapy and Synthetic Cannabinoids for Pain and Inflammation with Dr. Jim Woody 180 Life Sciences

Empowered Patient Podcast

Play Episode Listen Later Nov 29, 2023 19:14


Dr. Jim Woody, CEO and Director of 180 Life Sciences, discusses the company's vision for safer pain and inflammation management. Their earlier work on anti-TNF therapy revolutionized the treatment of conditions such as rheumatoid arthritis. Now 180 Life Sciences focuses on additional indications of inflammation, fibrosis, and cognitive dementia for using anti-TNFs. Jim highlights their research on the anti-inflammatory and analgesic properties of cannabinoids and the potential of synthetic cannabinoid analogs for pain management and appetite suppression. Jim elaborates, "Many years ago, I was Chief Scientific Officer at a company called Centocore, and they were one of the first companies developing therapeutic monoclonal antibodies. One of them that we developed was called anti-TNF. It was Infliximab, which was the FDA name that it received. In your body, circulating around, there are hundreds of small proteins. Those that modify the immune system are called cytokines, and most of them are good actors. One of the bad actors is what they call tumor necrosis factor. It was given that name because of some mouse studies in cancer that were done, although they turned out to be incorrect." "My colleagues in the UK, Dr. Marc Feldmann and Dr. Ravinder Maini had data suggesting that rheumatoid arthritis inflammation and pain were driven by TNF. We were the first to treat ten patients with anti-TNF in this program, in the whole world. Now, anti-TNF is the therapy of choice for rheumatoid arthritis, which, of course, is severe inflammation of the joints." "We also found out that TNF was driving these inflammations in Crohn's disease, Psoriasis, and in Ulcerative Colitis. We discovered all of those from Centocore, and now anti-TNF is the largest-selling class of biologics, at almost $40 billion a year. The current favorite is Humira from AbbVie, but J&J, who bought Centocore, still makes a billion dollars a year from Infliximab sales or its brand name Remicade." #180LifeSciences #LifeSciences #CBD #Biotech #Fibrosis #AntiTNF #DupuytrensDisease #PainManagement #Inflammation  180lifesciences.com Download the transcript here

Empowered Patient Podcast
Using Anti-TNF Therapy and Synthetic Cannabinoids for Pain and Inflammation with Dr. Jim Woody 180 Life Sciences TRANSCRIPT

Empowered Patient Podcast

Play Episode Listen Later Nov 29, 2023


Dr. Jim Woody, CEO and Director of 180 Life Sciences, discusses the company's vision for safer pain and inflammation management. Their earlier work on anti-TNF therapy revolutionized the treatment of conditions such as rheumatoid arthritis. Now 180 Life Sciences focuses on additional indications of inflammation, fibrosis, and cognitive dementia for using anti-TNFs. Jim highlights their research on the anti-inflammatory and analgesic properties of cannabinoids and the potential of synthetic cannabinoid analogs for pain management and appetite suppression. Jim elaborates, "Many years ago, I was Chief Scientific Officer at a company called Centocore, and they were one of the first companies developing therapeutic monoclonal antibodies. One of them that we developed was called anti-TNF. It was Infliximab, which was the FDA name that it received. In your body, circulating around, there are hundreds of small proteins. Those that modify the immune system are called cytokines, and most of them are good actors. One of the bad actors is what they call tumor necrosis factor. It was given that name because of some mouse studies in cancer that were done, although they turned out to be incorrect." "My colleagues in the UK, Dr. Marc Feldmann and Dr. Ravinder Maini had data suggesting that rheumatoid arthritis inflammation and pain were driven by TNF. We were the first to treat ten patients with anti-TNF in this program, in the whole world. Now, anti-TNF is the therapy of choice for rheumatoid arthritis, which, of course, is severe inflammation of the joints." "We also found out that TNF was driving these inflammations in Crohn's disease, Psoriasis, and in Ulcerative Colitis. We discovered all of those from Centocore, and now anti-TNF is the largest-selling class of biologics, at almost $40 billion a year. The current favorite is Humira from AbbVie, but J&J, who bought Centocore, still makes a billion dollars a year from Infliximab sales or its brand name Remicade." #180LifeSciences #LifeSciences #CBD #Biotech #Fibrosis #AntiTNF #DupuytrensDisease #PainManagement #Inflammation  180lifesciences.com Listen to the podcast here

A Real Change With Sandi Krakowski
#51 - How I Healed My Body And Got Off Remicade PT2

A Real Change With Sandi Krakowski

Play Episode Listen Later Nov 11, 2023 25:41


Part two of: How I Healed My Body And Got Off Remicade. In this episode Sandi talks about how to handle the challenges of taking control of your health and being your own advocate. She also shares the deep parts of growing our minds to create the kind of life we want.

A Real Change With Sandi Krakowski
#50 - How I Healed My Body And Got Off Remicade

A Real Change With Sandi Krakowski

Play Episode Listen Later Nov 2, 2023 35:49


In this episode Sandi shares what's been happening in the last year and a half in her personal life. How she has been on a healing journey and even got off Remicade is a big focus.    Lets connect.. @sandikrakowski IG Sandi's investment group www.arealchange.com

The Beautiful Bag
From Diagnosis to Determination: Meghan Brown's Inspiring Path to Ostomy Empowerment

The Beautiful Bag

Play Episode Listen Later Sep 6, 2023 49:43


Join LeeAnne Hayden and special guest Meghan Brown for an inspiring and informative episode of "The Beautiful Bag." In this conversation, they explore their journeys living with ostomy bags, discuss the challenges they've overcome, and share valuable insights on topics like pregnancy with an ostomy and the power of a positive mindset. Segment 1: Meghan's Crohn's Journey [00:00] Intro: LeeAnne Hayden introduces Meghan Brown, sharing their mutual admiration for each other. [02:37] Meghan's Crohn's Diagnosis: Meghan's journey with Crohn's disease began at a young age when she was diagnosed at 13. She endured a year of misdiagnosis and the struggles of managing her health while navigating high school. [04:15] Remission and High School: After starting Remicade, Meghan experienced significant improvements in her health. However, she reflects on the challenges she faced as a teenager dealing with steroids and rumors about her absence from school. [07:27] College and Recurrence: Meghan's life took a positive turn when she met her husband, but her sophomore year of college marked a recurrence of her illness. She explored various treatments, including Remicade, but encountered complications. [08:42] Decision for Surgery: A routine colonoscopy revealed precancerous signs, leading Meghan to make a challenging decision. She discusses the emotional and mental aspects of choosing to undergo surgery and embracing an ostomy bag to eliminate the risk of cancer. [09:37] Mental Health and Support: Meghan emphasizes the role of mental health throughout her journey and the importance of her parents' unwavering support. She shares how her family's positive outlook helped her during difficult times. Segment 2: Overcoming Challenges and Acceptance [13:10] Balancing Vanity and Health: Meghan and LeeAnne discuss the difficult decision they faced regarding surgery and ostomy bags. Both admit to struggling with the idea of having an ostomy bag due to aesthetic concerns. [16:06] Perspective Shift: Meghan reflects on the moment her perspective shifted during a conversation with her surgeon. He highlighted the importance of considering her future as a young mom and how her decision would impact her loved ones. [20:09] Privacy vs. Openness: LeeAnne and Meghan discuss the balance between privacy and openness regarding their ostomy bags. Meghan commends LeeAnne for being open on social media and showing her ostomy bag. [22:15] Meghan's Social Media Journey: Meghan shares her reasons for joining social media after her surgery and how sharing her journey helped her heal, find acceptance, and connect with others facing similar challenges. [24:06] Embracing Acceptance: Meghan describes her social media journey as a healing process that allowed her to accept her body and gain body confidence. LeeAnne shares her own experience with healing through acceptance. Segment 3: Pregnancy with an Ostomy and Self-Advocacy [28:11] Hidden Community: LeeAnne and Meghan highlight the curiosity and lack of awareness surrounding ostomies and the need for more visibility. [29:53] Pregnancy and Ostomy: Meghan shares her remarkable journey of having two healthy pregnancies with an ostomy. She emphasizes the need for more information and awareness around pregnancy with an ostomy. [35:03] Postpartum Challenges: Meghan discusses postpartum challenges related to her skin's reaction to ostomy products after childbirth and the importance of self-advocacy during life-changing events like pregnancy. [38:01] Self-Advocacy: LeeAnne and Meghan underscore the significance of self-advocacy, particularly for individuals with ostomies facing pregnancy. They stress the importance of open communication with healthcare professionals. [43:31] Mindset and Positivity: Meghan emphasizes the power of a positive mindset in coping with challenges and shares her personal journey of transforming her outlook. Segment 4: Embracing Life and Conclusion [46:06] Embracing Life: LeeAnne and Meghan discuss the importance of embracing life, even in the face of challenges. They acknowledge the value of returning to a positive perspective after moments of sadness and frustration. [46:55] Outro: LeeAnne Hayden expresses gratitude to Meghan Brown for sharing her experiences and insights on the podcast. She invites listeners to stay tuned for more episodes of "The Beautiful Bag" and the valuable stories and discussions it brings to light. Connect with Meghan & LeeAnne on Instagram  Connect with LeeAnne on Website 

The Beautiful Bag
Navigating Life with Chronic Illness: A Journey of Resilience and Transformation

The Beautiful Bag

Play Episode Listen Later Aug 23, 2023 48:57


Introduction: Host: LeeAnne Hayden Guest: Stephanie Brenner [00:00] Introduction: LeeAnne introduces the podcast and the guest, Stephanie Brenner. LeeAnne and Stephanie met at an ostomy convention. Stephanie's journey with chronic illness and surgeries is an inspiration to others. [0:41] Welcome Stephanie to the Podcast: LeeAnne welcomes Stephanie to the podcast. Stephanie expresses her gratitude for being on the show. [1:18] Stephanie's Journey with Chronic Illness: Stephanie shares her story, starting with her diagnosis of Crohn's disease in 2001 during high school. She quickly received a diagnosis and tried various medications, including steroids and Remicade. Stephanie discusses her journey through three surgeries: subtotal colectomy, J-pouch creation, and J-pouch closure. She talks about her challenges during college and how she learned to manage her condition. [5:10] Living Life Despite Chronic Illness: Stephanie reflects on her determination to live life to the fullest despite her condition. She shares her experiences of traveling and studying abroad, even when advised against it by doctors. Stephanie highlights the importance of making the most of life's opportunities. [11:18] Embracing Life with a Permanent Ostomy: Stephanie discusses her decision to undergo a permanent ostomy in 2018 after her J-pouch surgeries. She emphasizes the positive impact it had on her quality of life. Stephanie also talks about her breast cancer diagnosis and double mastectomy in 2019. She acknowledges the resilience and adaptability required to navigate these challenges. [14:34] Overcoming Hesitations and Fears: Stephanie shares her initial hesitation and fears about undergoing surgeries. She talks about the anticipatory anxiety and the mental struggle to make the decision. Stephanie encourages others to find ways to cope with the anxiety and fear surrounding surgeries. [16:50] Mental Health and Chronic Illness: LeeAnne and Stephanie discuss the importance of mental health when living with chronic illness. Stephanie highlights the prevalence of anxiety, depression, and trauma among individuals with chronic illnesses. She explains how these conditions manifest and affect patients' daily lives. [20:05] Coping Strategies for Mental Health: Stephanie discusses various coping strategies for managing mental health, including psychoeducation. She emphasizes the significance of connecting with one's body and exploring sensations. Stephanie encourages grounding exercises, joyful movement, breathwork, and sensory support. She mentions referring patients to somatic therapists and EMDR specialists for trauma-related issues. Stephanie promotes self-compassion and self-care. [24:05] Connecting with the Body: LeeAnne shares her experience with somatic therapy and connecting with her body. Stephanie emphasizes the importance of understanding the body's protective mechanisms. She encourages the use of pronouns to personalize the body's needs and feelings. Stephanie suggests practicing self-compassion and treating oneself as a caring guardian. [26:07] Conclusion: LeeAnne and Stephanie discuss the ongoing journey of self-love and self-acceptance. Stephanie reminds everyone that navigating life with a chronic illness is a collective journey. LeeAnne thanks Stephanie for sharing her inspiring story and insights. Find Stephanie: https://chronicillnesspsychotherapy.com Rome Foundation https://romegipsych.org  

Not So Different: a Podcast from The Center for Biosimilars
S6 Ep4: Biosimilars Gastroenterology Roundup for February 2023—Podcast Edition

Not So Different: a Podcast from The Center for Biosimilars

Play Episode Listen Later Mar 5, 2023 5:09


Show notes Eye on Pharma: Formycon Aflibercept Data; Sandoz CHMP Nod; Henlius Daratumumab Study https://www.centerforbiosimilars.com/view/eye-on-pharma-formycon-aflibercept-data-sandoz-chmp-nod-henlius-daratumumab-study Report: Over 60% of Providers Plan to Only Prescribe Interchangeable Adalimumab Biosimilars https://www.centerforbiosimilars.com/view/report-over-60-of-providers-plan-to-only-prescribe-interchangeable-adalimumab-biosimilars IQVIA: US Spending on Biosimilars to Reach $129 Billion Over Next 5 Years https://www.centerforbiosimilars.com/view/iqvia-us-spending-on-biosimilars-to-reach-129-billion-over-next-5-years Vizient Report Predicts Over 3% Inflation Rate for Biologics https://www.centerforbiosimilars.com/view/vizient-report-predicts-over-3-inflation-rate-for-biologics On the Come Up: What Vizient's Report Says About Inflation and Biosimilars https://www.centerforbiosimilars.com/view/on-the-come-up-what-vizient-s-report-says-about-inflation-and-biosimilars Patients With RA, IBD Trust Specialists' Biologic and Biosimilar Recommendations https://www.centerforbiosimilars.com/view/patients-with-ra-ibd-trust-specialists-biologic-and-biosimilar-recommendations Study: Higher Adherence Rates Among Users of the Remicade vs Infliximab Biosimilars https://www.centerforbiosimilars.com/view/study-higher-adherence-rates-among-users-of-the-remicade-vs-infliximab-biosimilars 

WONDERGIRLSAIDA
Shining A Light: Road To Starting Remicade & Humira For HS

WONDERGIRLSAIDA

Play Episode Listen Later Nov 30, 2022 4:22


Hello everyone in this episode I will be talking about how I am working with my medical team to get started with getting my HS under control with the treatments Remicade and Humira and so much more etc --- Send in a voice message: https://anchor.fm/wondergirlsaida/message

You're Great with Unique Hammond
Ryan M- Healing Story.

You're Great with Unique Hammond

Play Episode Listen Later Aug 21, 2022 53:32


Today's Podcast is a healing story from an Instagram LIVE I did with Ryan in 2020. Ryan began having symptoms in 2018 and was diagnosed with Crohn's soon after. Ryan started steroids and transitioned onto Remicade. It helped correct his downward spiral, but he was still struggling with gut and other health issues he wanted to clear up.At the urging of his wonderful girlfriend, he listened to my Podcast with Lacy Phillips on ToBeMagnetic and Soon after, he started my e-course. At first, Ryan started loosely, and as he saw results, he decided to set up his first call and go all in. Ryan wanted to feel great, build healthy habits and go into remission. I hope you enjoy my conversation with Ryan, and I hope it inspires you along your healing path.Connect with Unique on Instagram - https://www.instagram.com/uniquehammond/Find out how to work with Uniquehttps://www.youregreat.com/oneonone-consultsThe Bean Protocol -E-course - https://www.youregreat.com/the-bean-protocolTBM Podcast w/ me - https://tobemagnetic.com/expanded-podcast/2020/83

Crohnically Mom Podcast
CrohnicallyMom: Remicade and Pregnancy

Crohnically Mom Podcast

Play Episode Listen Later Jul 21, 2022 20:59


CrohnicallyMom: Remicade and Pregnancy by Michelle Pickens

pregnancy remicade
Heal “U” Podcast
Me, Behcet's and Remicade, Part 2

Heal “U” Podcast

Play Episode Listen Later Jun 7, 2022 16:57


Today, I continue the journey of sharing how I continue my journey of being a better Me living with Behcet's and taking Remicade. Support the show

remicade behcet
Heal “U” Podcast
Me, Behcet's and Remicade Part 1

Heal “U” Podcast

Play Episode Listen Later Jun 6, 2022 5:27


Sharing my journey living with Behcet's and Remicade Infusions!!! Support the show

sharing remicade behcet
LowCarbUSA Podcast
Reversing Ulcerative Colitis By Adopting a Carnivore Diet - Brett Ender: Ep 91

LowCarbUSA Podcast

Play Episode Listen Later Apr 14, 2022 41:16


Today we talk with Brett Ender (aka @MrSollozzo) and hear how he reversed debilitating ulcerative colitis by adopting a carnivore diet.  He had started to notice symptoms while at college but while serving an internship after that and commuting 4 hours a day by train to and from New York City.  He started to notice more and more blood in his stool but was too embarrassed to mention it to anyone and just assumed it would heal on its own.  But it just got worse and worse and at its peak he was going to the bathroom 30 times or more a day and effectively he was just passing straight blood!  Finally he tells a doctor and ends up on a drug called REMICADE which does help but it is $65,000 per infusion and he is told he will need an infusion every 6 - 8 weeks for the rest of his life. Then he stared to hear that a carnivore diet approach might help him and when he heard doctors like Shawn Baker talk about it he though it might be worth trying.  He started to notice improvements .  Before long all his symptoms had evaporated.  But he was still on the REMICADE and experiencing a lot of bad side effects from it.  He had to work really hard to convince his doctor to take him off it but finally he did and it's been plain sailing every since!!

IBD Heal
How I healed 10 Years of Ulcerative Colitis | Remicade & Entyvio Didn't Work

IBD Heal

Play Episode Listen Later Jan 31, 2022 69:15


We have been waiting to share Jacob's story on how he has been able to heal through a plant-based diet. Jacob worked with us for 6 months! This was one of the most incredible stories to health. I can't explain so it's best you listen to this testimonial from Jake on how he battled through years of flare-ups and medications to be where he is now, free of disease and how he has been able to have a Life After Colitis. Well done man, so proud of how far you have come and how far you will go. If you are done being sick take inspiration from a young man that never gave up and realised what true heath is. Free consultation: http://www.highcarbhealth.com/healthsurvey/

IBD Heal
Jacob Avoids Surgery and Heals from Ulcerative Colitis

IBD Heal

Play Episode Listen Later Jan 3, 2022 37:26


Today's episode is about how Jacob was able to avoid surgery and stop using all his Ulcerative Colitis medications. Free 30 Minute Consultation: http://www.highcarbhealth.com/healthsurvey/ Jacob's Testimony: I was diagnosed with ulcerative colitis in 2013 and put on Remicade along with a few other drugs to bring it under control. These drugs caused a lot of side effects and made me really constipated. My quality of life was low and at 18 years old I knew this wasn't the life I wanted to live so I started looking towards alternative ways of treating this disease. I tried all kinds of things like going gluten-free and the paleo diet. I eventually found that cutting animal products from my diet is what made me feel the best, so I went vegan but didn't really know what I was doing. In early 2020 my symptoms came back, and I started losing a lot of weight. Fortunately, I found High Carb Health on youtube and knew this was exactly what I needed! They sent me loads of information, books to read, and videos/documentaries to watch and for the next several days I immersed myself in all their knowledge and learned that the body will heal itself if given the proper conditions. So, for the next 6 months (and for the rest of my life) I worked on changing my lifestyle and giving my body the right conditions for healing. I had all the usual detox symptoms. Blood and mucus, fatigue, headaches, etc. but after a couple of months, I got better and better. I wasn't as tired, there was significantly less blood, and I started regaining my energy. Having already been vegan for two years, the change in diet was the easiest part for me. What I struggled most with was the mental side. Stress plays a significant role in healing and can slow or even prevent the healing process and Shukul and Shamiz helped me tremendously to deal with this. Now 6-7 months later and my health and vitality are returning to normal. I'm back to biking, running, camping, and living the active lifestyle that I love! Every week I continue to see more and more improvements with my digestion and am eating all the fruit and delicious potatoes I want. Shukul and Shamiz not only help you get over your disease, but they give you the knowledge to continue living a life free of colitis and can't thank them enough for their help and support!

IBD Heal
How to Heal Ulcerative Colitis | 40+ Bowel Movements | Padraig's Story

IBD Heal

Play Episode Listen Later Dec 6, 2021 43:41


In 2016 I was diagnosed with Ulcerative Colitis. I knew very little about the disease and was confident in the medics suggestion that it could be controlled by medication. After a round of steroids and Asacol, it subsided for 12 months. My second flare-up was much worse and I continued to flare up every 6 months with my medication being increased each time. Eventually, I was put on Remicade and then Entivio. My antibodies rejected the Entivio and by December 2019, I ended up in the hospital. At this stage, I was passing a lot of blood and needing the toilet 40+ times. They couldn't complete that colonoscopy due to the inflammation, even with morphine. Free consultation with High Carb Health: http://www.highcarbhealth.com/healthsurvey/ I was advised by the Gastro specialist that I would have no choice but to remove most of my colon and have a colostomy bag put into my body. I asked the specialist nurse if diet would help and she said absolutely not. The best thing I could do was go home and eat as much meat as possible to make me strong enough for surgery. She also suggested I have irreversible surgery because there was no coming back with my health. You can imagine how frustrated this made me feel. I knew there were other options and I was adamant I would exhaust trying these before I gave into surgery and life-changing surgery at that. While in hospital I revisited the Whole Food Plant-based Diet (I had attempted trying this in July without understanding it fully and I failed) and watched all of the HCH testimonials that I could fit in. I decided to take the plunge and contacted HCH in January to start the programme. In the meantime, I had worked with a well known Bioenergy specialist who definitely helped bridge the gap. I began on my healing through diet, exercise, hydrating correctly, sleeping correctly and looking at all the positivities in life. After speaking with both Shamiz and Shukul, I realised that this could have a really successful outcome for me if I was fully committed. Within a few weeks of the programme, I could already see huge improvements. I had two detoxes - the first one was easy and I thought that I was healed. The second one hit and removed all the toxins in the body that had built up over the years through food and medication. When I got out the other side of the second detox, I felt like I was running towards the finish line. Everything improved. My body started to rebuild itself by putting on healthy weight again, I had more energy than I ever had in my life before and I was only using the toilet 2/3 times a day with no urgency or symptoms of UC. I am now feeling better than I have ever felt in all my years. I am so grateful to High Carb Health that they worked with me in reversing UC and have given me a better life than I ever had, even before the diagnosis. I now look forward to living a healthy and happy life where I can do all the normal things that we all take for granted until we become ill. Most of all, I am free of medication and all of the horrible side effects that come with it.

My Immune System Hates Me!
R.A. Treatments Gone Wrong

My Immune System Hates Me!

Play Episode Listen Later Oct 29, 2021 33:55


Give Jenni a follow @gracefully.jen on Instagram.Check out our website, myimmunesystempod.com, where you can get in contact with Chelsey, listen to old episodes, learn about the RA Warrior Group, buy a signed copy of Chelsey's upcoming book, and apply to be a guest on the show.Don't forget to rate and review the show, and follow us on Instagram and Facebook @myimmunesystempodThis episode is sponsored by Grace & Able. Visit https://www.graceandable.com/discount/IMMUNE10 for 10% off your purchase. Follow Grace & Able on Facebook and Instagram.***Any information discussed in this podcast is strictly my opinion and those of my guests and are for informational purposes only. We are speaking from our personal experiences and you should always consult with your doctor or medical team.

My Immune System Hates Me!
Crohn's Disease with Lauren

My Immune System Hates Me!

Play Episode Listen Later Oct 22, 2021 33:51


Lauren's website is laurencunningham.co and you can find her ebook directly here. Follow her on Instagram @laur_cunningham.Check out our new website, myimmunesystempod.com, where you can get in contact with Chelsey, listen to old episodes, learn about the RA Warrior Group, buy a signed copy of Chelsey's upcoming book, and apply to be a guest on the show.Don't forget to rate and review the show, and follow us on Instagram and Facebook @myimmunesystempod***Any information discussed in this podcast is strictly my opinion and those of my guests and are for informational purposes only. We are speaking from our personal experiences and you should always consult with your doctor or medical team.

Sarc Fighter: Living with Sarcoidosis and other rare diseases
Episode 46 | Lisa Pflug is early in her journey with neurosarcoidosis, but already suffering the effects.

Sarc Fighter: Living with Sarcoidosis and other rare diseases

Play Episode Listen Later Oct 11, 2021 60:38


Lisa Pflug's hand started shaking one day and she couldn't make it stop.  For months neither she nor her doctors could explain it.  Then they started looking at her spinal cord, and they found the problem. In this Episode of the Sarc Fighter Podcast, Lisa shares the story of her journey through sarcoidosis, from her shaking hand to life on prednisone and hopefully a better life thanks to Remicade. Lisa is right handed and she is thankful sarcoidosis has only affected her left hand, allowing her to pursue her passion as a painter.  Here is one of her creations -- a flying egret. Promised links are below.  But here are a couple of photos from my trip to Zion, Grand Canyon, and Bryce National Parks.     Read about the patient trial with aTyr 1923 https://investors.atyrpharma.com/news-releases/news-release-details/atyr-pharma-announces-positive-data-phase-1b2a-clinical-trial Also -- Note that investors also believe in the promise of aTyr 1923: https://investors.atyrpharma.com/news-releases/news-release-details/atyr-pharma-announces-closing-863-million-public-offering   Bonus Episode on COVID-19 and Sarcoidosis https://beatsarc.podbean.com/e/bonus-episode-sarcoidosis-and-covid-19-presented-by-the-foundation-for-sarcoidosis-research/ Bonus Episode  Sarcoidosis and Prednisone: https://beatsarc.podbean.com/e/bonus-episode-sarcoidosis-town-hall-dealing-with-prednisone-presented-by-the-foundation-for-sarcoidosis-research/ MORE FROM JOHN Cycling with Sarcoidosis http://carlinthecyclist.com/category/cycling-with-sarcoidosis/ Watch the Prednisone Town Hall on YouTube https://youtu.be/dNwbcBIyQhE More on aTyr Pharma: https://www.atyrpharma.com/ Do you like the official song for the Sarc Fighter podcast?  It's also an FSR fundraiser! If you would like to donate in honor of Mark Steier and the song, Zombie, Here is a link to his KISS account.  (Kick In to Stop Sarcoidosis)  100-percent of the money goes to the Foundation.  https://stopsarcoidosis.rallybound.org/MarkSteier The Foundation for Sarcoidosis Research https://www.stopsarcoidosis.org/ Donate to my KISS (Kick In to Stop Sarcoidosis) fund for FSR  https://stopsarcoidosis.rallybound.org/JohnCarlinVsSarcoidosis?fbclid=IwAR1g2ap1i1NCp6bQOYEFwOELdNEeclFmmLLcQQOQX_Awub1oe9bcEjK9P1E My story on Television https://www.stopsarcoidosis.org/news-anchor-sarcoidosis/ email me  carlinagency@gmail.com S

Plant Based Briefing
99: The Best Diet for Crohn's Disease Treatment by Dr Michael Greger at NutritionFacts.org

Plant Based Briefing

Play Episode Listen Later Sep 9, 2021 7:58


Switching to a plant-based diet has been shown to achieve far better outcomes than those reported on conventional treatments in both active and quiescent stages in both Crohn's disease and ulcerative colitis. Dr. Michael Greger at NutritionFacts.org explains. Dr. Michael Greger is a physician, New York Times bestselling author, and internationally recognized speaker on nutrition, food safety, and public health issues. A founding member and Fellow of the American College of Lifestyle Medicine, Dr. Greger is licensed as a general practitioner specializing in clinical nutrition. He is a graduate of the Cornell University School of Agriculture and Tufts University School of Medicine. In 2017, Dr. Greger was honored with the ACLM Lifestyle Medicine Trailblazer Award and became a diplomat of the American Board of Lifestyle Medicine.   He Founded NUTRITIONFACTS.ORG is a non-profit, non-commercial, science-based public service provided by Dr. Michael Greger, providing free updates on the latest in nutrition research via bite-sized videos. There are more than a thousand videos on nearly every aspect of healthy eating, with new videos and articles uploaded every day.   His latest books —How Not to Die, the How Not to Die Cookbook, and How Not to Diet — became instant New York Times Best Sellers. His two latest books, How to Survive a Pandemic and the How Not to Diet Cookbook were released in 2020. View the trailer for How Not to Die here, and for How Not to Diet here.  100% of all proceeds he has ever received from his books, DVDs, and speaking engagements have always and will always be donated to charity. Original post: https://nutritionfacts.org/video/the-best-diet-for-crohns-disease-treatment/ Related episodes: 75: Healing Ulcerative Colitis with a Plant Based Diet Follow Plant Based Briefing on social media: Twitter: @PlantBasedBrief YouTube: YouTube.com/PlantBasedBriefing  Facebook: Facebook.com/PlantBasedBriefing  LinkedIn: Plant Based Briefing Podcast Instagram: @PlantBasedBriefing   #vegan #plantbased #Plantbasednutrition #veganpodcast #plantbasedpodcast #plantbasedbriefing #wfpb #wholefoodplantbased #drgreger #nutritionfacts #crohns #colitis #ulcerativecolitis #remicade #humira #budesonide #ibd #inflammatoryboweldisease  

Health Professional Radio - Podcast 454422
One-year results for STELARA in Crohn's disease - The head-to-head SEAVUE Study

Health Professional Radio - Podcast 454422

Play Episode Listen Later Jul 1, 2021 9:38


Returning guest, Dr. Andrew Greenspan, Vice President of Immunology Medical Affairs at Janssen discusses recent data from the Phase 3b SEAVUE study, the first head-to-head study of biologic therapies in patients with Crohn's disease, evaluating the safety and efficacy of STELARA® (ustekinumab) compared with adalimumab through one year of treatment in biologic-naïve patients. These data were presented at this year's Digestive Disease Week (DDW) Virtual 2021, where Janssen Immunology presented 20 abstracts in total from the company's gastroenterology portfolio and pipeline. As Vice President of Immunology Medical Affairs, Andrew Greenspan, M.D., is responsible for leadership and oversight of Immunology Medical Affairs activities supporting REMICADE® (infliximab), SIMPONI® (golimumab), SIMPONI ARIA® (golimumab for infusion), STELARA® (ustekinumab) and TREMFYA® (guselkumab) for a wide range of diseases, including rheumatoid arthritis, Crohn's disease, ulcerative colitis and psoriasis. #Immunology #CrohnsDisease #IBD

Adoptive Citizen
Dr. Jan T Vilcek - CEO & Chairman Vilcek Foundation

Adoptive Citizen

Play Episode Listen Later Jun 29, 2021 49:27


Episode 5 brings the extraordinary tale of biomedical scientist and philanthropist, Dr. Jan T. Vilcek. Dr. Vilcek and his wife, art historian Marica Vilcek, arrived in the United States as refugees from the former communist Czechoslovakia in 1965. In New York, Dr. Vilcek joined the faculty of NYU School of Medicine as a research professor. His work on cytokines – and specifically on Tumor Necrosis Factor alpha (TNF), were instrumental in the development of the first member of a new class of therapeutics called TNF blockers. Dr. Vilcek's contributions to the development of TNF blockers revolutionized the treatment of autoimmune disorders.  The success of treatments like Remicade® have generated significant royalties, which enabled Dr. and Mrs. Vilcek to establish the Vilcek Foundation in 2000. The Vilcek Foundation is a nonprofit private operating foundation; the mission of the foundation is to raise awareness of immigrant contributions in the United States and foster appreciation of the arts and sciences. To date, the Vilcek Foundation has awarded more than 11 million dollars in prizes and grants. Love and Science Book:  https://vilcek.co/loveandscience-acpodcast Vilcek Foundation:  https://vilcek.org

Healthy Eyes 101
Ep. 026: Causes and Treatments of Ocular Inflammation with Lou Chorich, MD

Healthy Eyes 101

Play Episode Listen Later Jun 20, 2021 35:12


Inflammation can occur in any part of the body and the eye is no exception. In this episode, we discuss uveitis and scleritis, two specific inflammatory conditions of the eye. Uveitis, one of the major causes of vision loss, is an intraocular inflammatory condition that can be broken up into three categories: infectious, non-infectious, and traumatic. It can further be classified by where the inflammation occurs in the eye: anterior (front part - iris), intermediate (middle part – ciliary body), posterior (back part – choroid), and panuveitis (entire eye).Infectious uveitis can be caused by bacteria, viruses, fungi, and parasites in the eye or by a systemic infection like herpes, tuberculosis, syphilis, toxoplasmosis, or Lyme disease. Noninfectious uveitis, the most common type, can be caused by autoimmune conditions like rheumatoid arthritis, lupus, sarcoidosis, Reiter syndrome, ankylosing spondylitis, Behcet's disease, psoriatic arthritis, and inflammatory bowel disease. The most common reason for uveitis is called idiopathic – no reason can be found. Symptoms of uveitis will vary according to its location in the eye. Anterior uveitis, also called iritis, can cause ocular pain, photophobia (light sensitivity), red eye, and decreased vision. Uveitis in the back of the eye mainly causes vision loss but usually does not cause pain.After a thorough eye examination, a lab work-up should be performed especially after the second recurrent episode or if the first episode affects both eyes. Ruling out an infectious cause can be done in the office. Bloodwork to rule out some of the autoimmune diseases is the next step. Sometimes a chest x-ray may be necessary to help rule out TB or sarcoidosis.Treatment of infectious uveitis is directed at the pathogen causing the infection. This may involve a combination of topical antibiotics or anti-virals and systemic medications. Steroids are the mainstay of treatment of non-infectious uveitis. Most anterior uveitis is treatable with topical steroid eye drops. Intermediate and posterior uveitis is mainly treated with oral steroids and steroid injections around or in the eye. For patients with chronic or recurrent uveitis, immunomodulatory therapies may be necessary. Some of these medications may include methotrexate, Cellsept, Humira, and Remicade.Scleritis is an inflammatory condition of the outer coating of the eye (sclera). Symptoms include severe eye pain, red eye, and sometimes a decrease in vision. If the back part of the eyewall is inflamed, the eye may not appear red. An ultrasound of the eye may be necessary to properly diagnose this condition. Some of the causes of scleritis include rheumatoid arthritis, HLA-B27-related diseases, and gout. Oral and injectable steroids are the primary treatments for this condition. Sometimes immunomodulatory therapies are also needed to control the inflammation. Here are some more links to learn more about inflammation in the eye.Uveitis.orgPreventblindness.org/uveitis/Scleritis To find out more about Dr. Lou Chorich and his practice, go to Midwest Retina's website.This is intended for informational and educational purposes only, and nothing in this podcast/blog is to be considered as recommending or rendering medical advice or treatment to a specific patient. Please consult your eye care specialist for proper diagnosis and treatment of any eye conditions that you may have.

The Bio Report
Finding New Uses for TNF Inhibitors

The Bio Report

Play Episode Listen Later Apr 8, 2021 22:26


TNF inhibitors, such as Humira and Remicade, have been a great biotech success story. These multi-billion franchises treat a range of autoimmune conditions including rheumatoid arthritis, psoriasis, and Crohn's disease. Jim Woody, who led Centocor's development team for Remicade, the first of the TNF-inhibitors, is today in pursuit of new uses for these therapies. Now CEO of 180 Life Sciences, Woody and his team are pushing TNF inhibitors into new indications for inflammatory and fibrotic conditions. We spoke to Woody about the role of TNF in the inflammatory process, the indications his company is pursuing, and why these well-established drugs have gone untapped for these purposes. The Bio Report welcomes DeepDyve as a sponsor. Search 100 million scientific papers with full access to 20 million articles. It's one-stop, affordable research. Try the enterprise version of the service free for one month. Go to deepdyve.com/podcast and use the code BIOREPORT

The NetworkNewsAudio News Podcast
180 Life Sciences Corp. (NASDAQ: ATNF) Developing Groundbreaking Anti-Inflammatory Therapeutics [Video Edition]

The NetworkNewsAudio News Podcast

Play Episode Listen Later Mar 26, 2021 16:29


In a natural response to injury or infection, the body produces chemicals that trigger the immune system to release antibodies and proteins plus increase blood flow to the afflicted area, which aids healing and produces inflammation. However, the immune system and the inflammatory processes have pernicious aspects far removed from beneficial healing. In fact, inflammation has been directly linked to a wide variety of physical and mental health maladies. Inflammation is also a symptom of infectious diseases, implicated in noninfectious diseases, and new findings show a causal relationship with postsurgical trauma. Inflammatory diseases are recognized as the most significant cause of death in the world, with more than 50% of all deaths attributed to inflammation-related diseases. The recognition of the connection between inflammation and disease sparked a flurry of biotech research and a new generation of drug development to treat previously untreatable disorders. World renowned scientists that now lead 180 Life Sciences Corp. (NASDAQ: ATNF) (180 Profile) pioneered the research and development of one of the first anti-inflammatory therapeutics to ever reach market, and today these drugs generate multiple billions of dollars in annual sales. Critical to creation of some the most important and profitable drugs ever on the market, the 180 team is in hot pursuit of new anti-inflammatory blockbusters with active programs in both preclinical and clinical studies. The world's largest and most broadly based health-care company, Johnson & Johnson (NYSE: JNJ), owns Remicade (infliximab), a blockbuster several times over with approved use in a range of inflammatory diseases. The founders of 180 Life Sciences discovered the anti-TNF (tumor necrosis factor) drug class that led to the development of Remicade and to a $4.9 billion merger between JNJ and Centocor Biotech. AbbVie Inc. (NYSE: ABBV) owns Humira, an anti-TNF therapeutic and top-selling drug in the world. The scientists at 180 Life Sciences licensed the anti-TNF technology in development of Humira. One of the world's leading biotech's, Amgen Inc. (NASDAQ: AMGN), bought Celgene's blockbuster anti-inflammatory drug Otezla in 2019 for $13.4 billion in cash, and Eli Lilly (NYSE: LLY) recently announced a deal for Rigel Pharmaceuticals' autoimmune and inflammatory diseases treatment for $960 million. In addition to delivering much-needed relief for previously untreatable maladies, eye-popping sales and king-sized acquisitions are likely to accelerate in the anti-inflammatory space, as more new and highly effective drugs come to market.

The NetworkNewsAudio News Podcast
180 Life Sciences Corp. (NASDAQ: ATNF) Developing Groundbreaking Anti-Inflammatory Therapeutics

The NetworkNewsAudio News Podcast

Play Episode Listen Later Mar 26, 2021 16:29


In a natural response to injury or infection, the body produces chemicals that trigger the immune system to release antibodies and proteins plus increase blood flow to the afflicted area, which aids healing and produces inflammation. However, the immune system and the inflammatory processes have pernicious aspects far removed from beneficial healing. In fact, inflammation has been directly linked to a wide variety of physical and mental health maladies. Inflammation is also a symptom of infectious diseases, implicated in noninfectious diseases, and new findings show a causal relationship with postsurgical trauma. Inflammatory diseases are recognized as the most significant cause of death in the world, with more than 50% of all deaths attributed to inflammation-related diseases. The recognition of the connection between inflammation and disease sparked a flurry of biotech research and a new generation of drug development to treat previously untreatable disorders. World renowned scientists that now lead 180 Life Sciences Corp. (NASDAQ: ATNF) (180 Profile) pioneered the research and development of one of the first anti-inflammatory therapeutics to ever reach market, and today these drugs generate multiple billions of dollars in annual sales. Critical to creation of some the most important and profitable drugs ever on the market, the 180 team is in hot pursuit of new anti-inflammatory blockbusters with active programs in both preclinical and clinical studies. The world's largest and most broadly based health-care company, Johnson & Johnson (NYSE: JNJ), owns Remicade (infliximab), a blockbuster several times over with approved use in a range of inflammatory diseases. The founders of 180 Life Sciences discovered the anti-TNF (tumor necrosis factor) drug class that led to the development of Remicade and to a $4.9 billion merger between JNJ and Centocor Biotech. AbbVie Inc. (NYSE: ABBV) owns Humira, an anti-TNF therapeutic and top-selling drug in the world. The scientists at 180 Life Sciences licensed the anti-TNF technology in development of Humira. One of the world's leading biotech's, Amgen Inc. (NASDAQ: AMGN), bought Celgene's blockbuster anti-inflammatory drug Otezla in 2019 for $13.4 billion in cash, and Eli Lilly (NYSE: LLY) recently announced a deal for Rigel Pharmaceuticals' autoimmune and inflammatory diseases treatment for $960 million. In addition to delivering much-needed relief for previously untreatable maladies, eye-popping sales and king-sized acquisitions are likely to accelerate in the anti-inflammatory space, as more new and highly effective drugs come to market.

Biotech 2050 Podcast
48. Anti-TNF: From Arthritis to Dementia and Fibrosis, Jim Woody, CEO, 180 Life Sciences

Biotech 2050 Podcast

Play Episode Listen Later Mar 3, 2021 22:53


Jim Woody has more than 25 years of pharmaceutical research and management expertise He currently serves as Chairman of Oncomed Pharmaceuticals, where he was previously a founder and CEO; he is also a General Partner at Latterell Venture Partners, a venture capital group focusing on early-stage healthcare companies He has served in a variety of health and management roles including as President of Roche Bioscience, and CSO and Senior Vice President of R&D for Centocor. At Centocor, Jim was part of the team that discovered Remicade, used to treat arthritis and which is now one of the best-selling drugs in the world. He served as Commanding Officer and Director at the US Naval Medical Research and Development Command in Bethesda, Maryland In this role he was responsible for the surveillance, detection and therapy for all biologic warfare agents and infectious diseases in the First Gulf War; he was awarded the US Navy Legion of Merit for his service He holds an MD from Loma Linda University, and trained in pediatric immunology at Duke University and Boston Children’s Hospital (Harvard) He further holds a PhD in Immunology from the University of London, and has co-authored more than 140 publications

Arthritis Life
Life with Arthritis is a Marathon, Not a Sprint: Christy Williams’ Story

Arthritis Life

Play Episode Listen Later Feb 4, 2021 66:58


Christy Williams is a certified health coach, wife, mother of two and endurance athlete/triathlete. She has been living with an autoimmune disease called Sero-negative spondylarthopathy (blood negative inflammatory arthritis) since the age of 24. She is now 48 and has been in remission for 15 years due to a combination of Remicade (a biologic disease modifier) and an active healthy lifestyle. Cheryl Crow is an occupational therapist who has lived with rheumatoid arthritis for seventeen years. She is passionate about helping others with rheumatoid arthritis thrive despite arthritis. She formed the educational company Arthritis Life in 2019 after seeing a need for more engaging, accessible, and (dare I say) FUN patient education and self-management resources. Episode links:Christy’s Instagram: @coachchristy10 Free Handout: Cheryl’s Master Checklist for Managing RACheryl’s Facebook group: Arthritis Life Podcast, Practical Tips & Positive, Realistic SupportThe Happiness Trap book by Russ HarrisCheryl on InstagramCheryl’s website: Arthritis LifeCheryl’s Tiktok: @ArthritisLife Arthritis Life Facebook PageCheryl’s Twitter: @realcc This episode is brought to you by the Rheumatoid Arthritis Roadmap, an intensive online education and support program Cheryl created to empower people with the tools to confidently manage everyday life with rheumatoid arthritis.Medical disclaimer: All content found on the Arthritis Life public channels was created for generalized informational purposes only. The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment.Show Breakdown: 01:00 – Christy shares her diagnosis at 24 after the birth of her first child, and her transition into adulthood. 03:20 – Christy’s tenacious drive to stay active, her journey completing an ironman challenge. 5:35: How Christy has managed her inflammatory arthritis over the years: it’s a marathon not a sprint! How she went from being in a wheelchair to completing triathalons after figuring out the right medication and lifestyle interventions such as exercise.8:00 - Christy explains how fatigue still affects her quality of life, and how she copes with it by pacing herself.13:05– Christy shares why and how she became a health coach for people with autoimmune disease, after she achieved remission. 20:30 – How having an autoimmune disease sparked Christy and Cheryl to confront their mortality.23:10 – Christy’s definition of “remission,” and additional reflections on the fact that no two paths towards remission are the same.30:10 – Cheryl and Christy share different debates and challenges within the chronic illness community, including medication shaming, or shaming of people who celebrate natural methods.34:40 - Cheryl reflects on how she’s tried to strike a balance between celebrating how well Western medications have worked for her and also respecting others’ choices if they differ, and how patients within the chronic illness community can unite in our common goals and consider the intent of our messages when we communicate our journeys.36:00 - How Christy & Cheryl cope with unsolicited advice.38:00 - How Cheryl’s therapy helped her cope with uncertainty and gray areas during treatment for RA.41:25 – How Christy has managed her attitude and mindset during the ups and downs of life with inflammatory arthritis.43:38– Cheryl shares how Acceptance and Commitment Therapy transformed her relationship to uncertainty as a chronic illness patient, and how anxiety makes you want black and white answers and certainty.  50:00 – Common misconceptions and myths around arthritis and remission.54:27 – Christy’s advice for anyone battling chronic illness and her best coping mechanisms dealing with uncertainty  57:00 - Christy’s pre-diagnosis challenges with people not believing her.1:03:00 - The importance of sharing our stories, even if we get criticized or misunderstood! 

Sarc Fighter: Living with Sarcoidosis and other rare diseases
Diet and CBD - Can they be effective? Ryan Norenberg offers proof.

Sarc Fighter: Living with Sarcoidosis and other rare diseases

Play Episode Listen Later Feb 1, 2021 86:58


Ryan Norenberg is fighting cardiac sarcoidosis with a one-two punch that includes the use of CBD oil and a holistic diet.  Many people who have appeared on the Sarc Fighter podcast have been frustrated by the lack of choices when it comes to treatment of their disease.  There is a menu of medicines that people are familiar with ranging from prednisone to Remicade to Imuran and others.  For many people, these are only marginally effective. So you ask yourself, "What if I just ate better?" or "Should I avoid certain foods?"Ryan says yes.  In fact his wife is now a certified Holistic Nutritionist.In addition, Ryan has turned to a newer alternative - CBD oil.  In this podcast, he explains how he uses this over-the-counter therapy to reduce inflammation. Give the podcast a listen and see if there isn't an opportunity for you to make some lifestyle adjustments, that could improve your situation.Additional notes from Ryan!Lindsey Norenberg's Website www.nourishbylindsey.comRealm of Caring website https://realmofcaring.org/Here are a couple related to the Omega6/3 topic: https://pubmed.ncbi.nlm.nih.gov/12442909/This is an abstract to a research document that one would need to pay for but you can get the idea of it in the abstract provided. https://www.healthline.com/nutrition/optimize-omega-6-omega-3-ratioThis is a good one I found geared more towards the layman.  It explains the importance while providing some specific information about different foods and sources of omega 6’s and 3’s.As it is with CBD, it is important to get fish oil from a reliable source.  As it is unregulated, there is a potential of high mercury content.  Additionally, it is recommended to consume in a true liquid oil form that is stored and shipped at cooled temperatures vs capsules that have been on a store or warehouse shelf for unknown time at unknown temperatures.  I currently use Nordic Naturals Ultimate Omega liquid available on Amazon and shipped with a cold pack.  I take 2800 mg/daily (1 teaspoon). The probiotic I take is Ther Biotic complete.  This one has 12 strains of bacteria. Here are some related to cannabinoid therapy: Cannabinoids-as-novel-anti-inflammatory-drugs.pdfThis one focuses more on THC than CBD specifically but provides a good overview of our endocannabinoid system and how it works. https://realmofcaring.org/roc-research/research-library/?_sft_condition_=inflammation&_sfm_publication_year=1972+2022Here is a group related to inflammation Research Library - Realm of Caring FoundationHere is a group of research articles related to cannabinoids and their impact on immune function. https://store.healthylivingshop.com/Here is a link to the Cleveland Clinic Healthy Living Shop.  The supplements on this site have been vetted by the CC and they consider trustworthy and reliable.  However, that doesn’t mean that there are not other good options out there but the buyer needs to beware. https://www.charlottesweb.com/This is my trusted source of CBD.  There are several other good ones out there as well.  They offer different types (gummies, oil, lotions…) and different ratios of CBD/THC ranging from 100% CBD isolate to full plant extract containing up to the .03% federal limit on THC content. R44742.pdfHere is an article I found describing the legislation that established the hemp laws. Ryan also advises: .03% THC adds up and is not completely negligible in its effects at higher doses.  The Realm of Caring can offer some support here as well. If you do decide to try CBD, I recommend you read up on the “entourage effect”.  You can find some articles on the Realm of Caring Research Library page.  Basically, studies are limited but there is evidence to believe that CBD is more effective in the presence of THC and other cannabinoids vs isolated by itself.  Charlotte’s Web offers discounted pricing if you register with them and offers further discounts if you subscribe to recurring deliveries.  I have found the subscription to be the most cost-effective way to get it.  

Health Professional Radio - Podcast 454422
180 Life Sciences - Clinical Programs

Health Professional Radio - Podcast 454422

Play Episode Listen Later Dec 1, 2020 7:56


Dr. James (Jim) Woody, CEO of 180 Life Sciences Corp., a newly formed clinical-stage biotech company focused on novel drugs for unmet needs in inflammatory diseases, fibrosis, and pain, discusses three clinical programs using anti-TNF, with the lead program in Phase 2b/3 for Dupuytren's contracture, a fibrotic disease of the hand. He previously led the team responsible for developing Remicade, the first of the TNF inhibitor biologics.

ceo phase thursday night football life sciences clinical programs dupuytren remicade
Crohn's Fitness Food
Shelly Sulfrain: Ulcerative Colitis Warrior (E63)

Crohn's Fitness Food

Play Episode Listen Later Nov 12, 2020 45:22


In today’s episode, 12-year Ulcerative Colitis Warrior Shelly Sulfrain shares her IBD journey and how an ileostomy gave her back her life. At the age of 29, Shelly was working as a pharmacist and enjoying life, having just finished school. Then, her first symptom of blood in her stool led her to a trip to the emergency room. It took a few more visits to her primary care doctor and eventually a gastroenterologist to finally diagnose Ulcerative Colitis. From there, she faced a number of highs and lows as she cycled through medications and faced life-threatening side effects throughout the course of her journey.  Over the years, Shelly found brief periods of remission, but ultimately kept finding herself back in a flare and struggling to keep the symptoms away. She battled one major flare right before her wedding and found remission on Imuran while she carried her baby. But, after delivering a healthy baby boy, she went into her worst flare yet and was started on Remicade. Four years later, she experienced a life-threatening side effect. The brain fog she developed and difficulty in finding the right words were a result of her neurons not functioning properly; a rare side effect of Remicade. It also meant there was a chance that she might only have a few months to live. While an MRI confirmed that she was not facing death, the damage that had been done was not reversible.  Her options for medications were dwindling and, for Shelly, it was a sign that the disease was getting worse and that it was winning. She went on to try Entivyo, Humira, and Xeljanz, but nothing worked. By this point, she was in a bad place emotionally and mentally and she leaned into meditation, prayer, and journaling to help her cope with the anxiety, stress, and depression. Finally, her doctor suggested surgery. While she dismissed the idea at first, after reaching out to a number of different ostomy advocates on Instagram, she was ready to consider it. She gave one last effort to exhaust all non-surgical options and sought the help of a functional medicine doctor. After she still couldn’t find relief, she was ready for surgery. Though she faced a number of complications after her first j-pouch surgery, a year later Shelly had an ileostomy and today is living life to the fullest. She’s gained a lot of insight over the years and although times may get tough and bleak, she recognizes that having a positive outlook is vital and encourages others to remember that they are not alone. Follow Shelly on Instagram at:https://www.instagram.com/shellsgotguts/@shellsgotguts

The NetworkNewsAudio News Podcast
180 Life Sciences Corp. Founders Leverage History of Success Developing, Selling New Drugs to Big Pharma

The NetworkNewsAudio News Podcast

Play Episode Listen Later Oct 23, 2020 13:10


Pharmaceutical companies invest enormous amounts of time and money on the research and development of new drugs, typically years in the making and costing millions of dollars. Only occasionally is a new drug developed that's approved and generates more than $1 billion per year in sales, a benchmark in the industry commonly called a “blockbuster.” Blockbusters are scarce, but the proverbial quest for blockbuster drugs continues unabated because of vast unmet medical needs and because blockbuster therapeutics can be worth tens of billions of dollars during their patent-protected lives. Little wonder that pharmaceutical giants often buy up promising new drugs, some even in their infancy, not just to fill their pipeline or mesh with current R&D projects but also to bank on a bonanza of prospective revenues that could exceed $100 billion. With so much at stake, it only makes sense to pay special attention to scientists who have previously developed and delivered these blockbusters. With this in mind, expectations are high for 180 Life Sciences Corp. (180 Profile) since the founders have significant expertise in developing new therapeutics that were sold to big pharma for billions. They are renowned for development of some of the largest-selling drugs to ever come to market. Now they aim to do it again with a pipeline of drug candidates in sequential stages of development that address large untapped markets. The founding scientists at 180 Life Sciences discovered the anti-TNF drug class that led to Remicade, the fourth all-time best-selling drug in the world.

The NetworkNewsAudio News Podcast
180 Life Sciences Corp. Founders Leverage History of Success Developing, Selling New Drugs to Big Pharma [Video Edition]

The NetworkNewsAudio News Podcast

Play Episode Listen Later Oct 23, 2020 13:11


Pharmaceutical companies invest enormous amounts of time and money on the research and development of new drugs, typically years in the making and costing millions of dollars. Only occasionally is a new drug developed that's approved and generates more than $1 billion per year in sales, a benchmark in the industry commonly called a “blockbuster.” Blockbusters are scarce, but the proverbial quest for blockbuster drugs continues unabated because of vast unmet medical needs and because blockbuster therapeutics can be worth tens of billions of dollars during their patent-protected lives. Little wonder that pharmaceutical giants often buy up promising new drugs, some even in their infancy, not just to fill their pipeline or mesh with current R&D projects but also to bank on a bonanza of prospective revenues that could exceed $100 billion. With so much at stake, it only makes sense to pay special attention to scientists who have previously developed and delivered these blockbusters. With this in mind, expectations are high for 180 Life Sciences Corp. (180 Profile) since the founders have significant expertise in developing new therapeutics that were sold to big pharma for billions. They are renowned for development of some of the largest-selling drugs to ever come to market. Now they aim to do it again with a pipeline of drug candidates in sequential stages of development that address large untapped markets. The founding scientists at 180 Life Sciences discovered the anti-TNF drug class that led to Remicade, the fourth all-time best-selling drug in the world.

The NetworkNewsAudio News Podcast
180 Life Sciences Corp. Dedicated to Developing Groundbreaking Anti-Inflammatory Drugs

The NetworkNewsAudio News Podcast

Play Episode Listen Later Oct 5, 2020 16:10


Inflammation typically occurs in the body as a natural response to threats such as infection or injury, but chronic inflammation can cause severe damage and even death. Inflammation is a well-known symptom of multiple infectious diseases. However, multidiscipline research strongly suggests that inflammation is also closely linked with a broad range of noninfectious diseases. The critical aspects of the interplay between inflammation and disease may well be the key to development of a new generation of drugs to treat previously untreatable diseases, sparking a flurry of biotech research and development in the field. At the vanguard of this new drug development, 180 Life Sciences Corp. (NASDAQ: KBLM) is driving groundbreaking studies in clinical programs aimed at developing novel therapeutics that address distinct areas of inflammation, finally offering hope for vast unmet medical needs in inflammatory diseases, fibrosis, pain and more. Amgen Inc. (NASDAQ: AMGN) acquired the anti-inflammatory drug Enbrel for $4.8 billion in 2018 and, in conjunction with AbbVie Inc. (NYSE: ABBV) and others, is testing anti-inflammatory drugs in a joint COVID-19 study. Actemra, an anti-inflammatory arthritis drug from Roche Holding Ltd. (OTCQX: RHHBY) previously failed to meet its primary endpoint in earlier COVID trials. Johnson & Johnson (NYSE: JNJ) now owns Remicade, which was developed by the current management of 180 Life Sciences, the first tumor necrosis factor-α (TNF) inhibitor and one of the top anti-inflammatory drugs in the world with over $5 billion in sales in 2019 alone.

The NetworkNewsAudio News Podcast
180 Life Sciences Corp. Dedicated to Developing Groundbreaking Anti-Inflammatory Drugs [Video Edition]

The NetworkNewsAudio News Podcast

Play Episode Listen Later Oct 5, 2020 16:11


Inflammation typically occurs in the body as a natural response to threats such as infection or injury, but chronic inflammation can cause severe damage and even death. Inflammation is a well-known symptom of multiple infectious diseases. However, multidiscipline research strongly suggests that inflammation is also closely linked with a broad range of noninfectious diseases. The critical aspects of the interplay between inflammation and disease may well be the key to development of a new generation of drugs to treat previously untreatable diseases, sparking a flurry of biotech research and development in the field. At the vanguard of this new drug development, 180 Life Sciences Corp. (NASDAQ: KBLM) is driving groundbreaking studies in clinical programs aimed at developing novel therapeutics that address distinct areas of inflammation, finally offering hope for vast unmet medical needs in inflammatory diseases, fibrosis, pain and more. Amgen Inc. (NASDAQ: AMGN) acquired the anti-inflammatory drug Enbrel for $4.8 billion in 2018 and, in conjunction with AbbVie Inc. (NYSE: ABBV) and others, is testing anti-inflammatory drugs in a joint COVID-19 study. Actemra, an anti-inflammatory arthritis drug from Roche Holding Ltd. (OTCQX: RHHBY) previously failed to meet its primary endpoint in earlier COVID trials. Johnson & Johnson (NYSE: JNJ) now owns Remicade, which was developed by the current management of 180 Life Sciences, the first tumor necrosis factor-α (TNF) inhibitor and one of the top anti-inflammatory drugs in the world with over $5 billion in sales in 2019 alone.

Crohn's Fitness Food
Nicole Candelaria: IBD Journey Part 2 (E58)

Crohn's Fitness Food

Play Episode Listen Later Jun 15, 2020 50:01


In today’s episode, we continue Nicole Candelaria’s story from her decision to begin traveling to and from New York to see a gastroenterologist who specializes in IBD. Everything happened quickly as her new doctor was determined to not let her suffer any longer, but she quickly became weary of the travel and the reluctance of her doctors in Florida to cooperate.  In New York, however, her doctor blew her away with the amount of information she knew about IBD and her willingness to explain and discuss in detail the answers to many of Nicole’s questions that her doctors in Florida were never able to give. From medications to surgical options, her new doctor shared the reasoning behind every step of her treatment plan.  This past fall, Nicole went on short-term disability and began seeing her doctor in New York once a week. As she began healing, her visits dropped to every other week and then every few weeks. Using Methotrexate to help her transition from Remicade to Stelara, Nicole and her doctor finally started to see an improvement just this past February.  It was then, after all the years battling IBD and only achieving remission for one brief period, Nicole finally had hope and she realized that in order to get better she needed to move to New York to be able to continue this journey with her new doctor. As the timing worked out, she was able to move and get settled into a place in New Jersey just before the Coronavirus pandemic hit the U.S. in March.  Today, Nicole is vibrant, energetic, and thriving. Looking back, she realizes what a shell of her former self she had become – not realizing she was simply going through the motions day in and day out. Now, she’s happy, appreciating every moment of life, and sharing her story with the IBD community. One of her biggest struggles throughout her journey, with all the highs and lows that IBD brings, was body image. Nicole often found herself hating her body for fighting against her, she was uncomfortable, and had no self love. Over the years, however, she gained a different outlook. Her experiences with IBD, she said, were humbling and she learned to love and be grateful for her body and everything it was doing to fight FOR her. With that new perspective, she created her Instagram handle, @crohnsically_beautiful, and began sharing her journey to help provide comfort and show others that they are not alone.  To those who are newly diagnosed, Nicole gives a reminder that you will get through it, you’re not alone. For those who are currently battling flare ups, “you’ve got this!” And for family members, she shares the importance of reading up and becoming as informed as possible to help better understand the person in your life with IBD. ---- Follow Nicole: www.instagram.com/crohnsically_beautiful

Crohn's Fitness Food
Nicole Candelaria: Crohn's Disease, Ulcerative Colitis, and Perianal Crohn's (E57)

Crohn's Fitness Food

Play Episode Listen Later Jun 8, 2020 57:50


In today’s episode, Nicole Candelaria shares her IBD journey that began in 2007 during her first semester in college. After ignoring the symptoms for a few months–attributing them to stress–she finally went to the hospital and a colonoscopy revealed both Crohn’s Disease and Ulcerative Colitis. From there, life became a roller coaster.  Like many who are unfamiliar with IBD, she was overwhelmed. Her life changed dramatically as flare ups prevented her from doing the things she loved. From band to athletics, she started losing a sense of who she was as IBD started to define her. She was put on a number of different medications over the next few years, from antibiotics and steroids to 6MP and Remicade, but nothing gave her the relief she was searching for and a few resulted in serious side effects. Nicole’s search for remission led her to a naturopathic doctor, and although she was able to achieve a brief period of remission by listening to his advice, changing her diet to a vegon one, and taking a variety of supplements and herbs, it didn’t last. Over the next couple of years she found herself back in the emergency room on multiple occasions. She experienced intestinal blockages, partial blockages, fistulas, and had part of her small intestine collapse and deteriorate over her large intestine–dangerously close to ruptering. During one surgery, she had 10 inches of her large intestine removed and 12 inches of her small intestine. Between her surgery and blood infusions on separate occasions, Nicole said it was eye opening to just how serious IBD and the long-term effects of inflammation are.  In 2017, Perianal Crohn’s Disease was added to her list of diagnoses and changes to insurance forced her to switch doctors. It started a search that led her to multiple physicians and discovering the difference that a doctor who specializes in IBD can make. Her search for relief eventually led her to a doctor in New York, over 1,200 miles away from her home in Florida. It was during her search that Nicole also realized the importance of advocating for herself and listening to what her body was telling her.  Like many others, her journey has been–and continues to be–a long and winding one. Though she found herself wishing for the guide book on how to cope and accept IBD, she recognizes that everyone’s journey is different and that there’s not one clear path. In this episode, we break here in Nicole’s story and will pick up next week as she continues her journey with a new gastroenterologist in New York who specializes in IBD. ---- Follow Nicole: www.instagram.com/crohnsically_beautiful

Sarc Fighter: Living with Sarcoidosis and other rare diseases
Episode 9 COVID-19 & Sarcoidosis: What are the real risks? First data with Dr. Robert Baughman

Sarc Fighter: Living with Sarcoidosis and other rare diseases

Play Episode Listen Later May 5, 2020 35:13


Are sarcoidosis patients more likely to get COVID-19 and if they do, will outcomes be worse?  For the first time, medical science has an answer to that question.  Just in are the results of a study conducted by the University of Cincinnati, Albany Medical Center, and The Foundation for Sarcoidosis Research.   The study was headed by Dr. Robert Baughman of the University of Cincinnati who talked to the Sarc Fighter Podcast about his findings.Take the survey:  https://redcap.research.cchmc.org/surveys/?s=TJXWAK4FCJHere is Dr. Baughman's bio: Dr. Baughman is Professor of Medicine at the University of Cincinnati. After completing undergraduate training at Yale University, he received his medical degree from Case Western Reserve School of Medicine. He joined the Internal Medicine staff at the University of Cincinnati after completing both an Internal Medicine residency and fellowship training in pulmonary diseases at the University of Cincinnati. His major research interests include: the treatment of sarcoidosis and bronchoalveolar lavage. Along with his long time collaborator Dr. Elyse Lower, he has developed several novel treatments for sarcoidosis, including methotrexate, thalidomide, leflunomide, and infliximab. Current studies include treatments for sarcoidosis associated fatigue and pulmonary hypertension due to sarcoidosis. He is on the editorial board of multiple subspecialty journals, and his publications include over 150 original papers and over 70 review articles and/or book chapters. He is on the editorial board of several journals, including American Journal of Respiratory and Critical Care Medicine and Chest. In addition, Dr. Baughman is the recent editor of books on sarcoidosis, interstitial lung disease, and ventilator associated pneumonia. He has been an active member of WASOG since its inception and is President Emeritus.Here is the New Release from the study:On April 27, 2020, the Johns Hopkins University Coronavirus Resource Center reported that over 3 million individuals world wide have been infected with COVID-19, including 979,077 in the United States. The vast majority are adults. In the United States, approximately 210 million individuals are above the age of 18. About 200,000 of these people have sarcoidosis.COVID-19 has changed our world. In sarcoidosis, there have been many questions asked about COVID-19. These include:Is a sarcoidosis patient more likely to get COVID-19 infection?If a sarcoidosis patient becomes infected, does he or she have a worse outcome?Is there increased risk if a patient is taking prednisone or other immunosuppressive drugs?Does taking hydroxychloroquine protect a sarcoid patient from COVID-19?Does race affect the risk or the outcome for COVID-19?In order to answer these questions, The Foundation for Sarcoidosis and University of Cincinnati launched a questionnaire three weeks ago. They asked their patients to tell them if they had been infected with COVID-19 or not. If infected, they were asked to report what happened.To date, over 1600 sarcoidosis patients have responded. Of these, only 31 patients, which is less than 2% of the total, reported having COVID-19 and most were able to be treated at home. None required mechanical ventilation.We were unable to identify an increased risk associated with race, use of prednisone, or treatment with infliximab (Remicade). Also, the use of hydroxychloroquine (plaquenil) was neither protective nor a risk factor for infection.Dr Robert Baughman, principal investigator of the study, had the following comment: “When COVID-19 began, there was controversy about the additional risks of sarcoidosis and treatments. This information, although only preliminary, found the rate of infection only slightly higher than the national average. Also, sarcoidosis patients with COVID-19 mostly did well, which is what we are seeing for many of our other patients.” Dr. Elyse Lower, co-director of the University of Cincinnati Sarcoidosis center added, “Thank you FSR for working on getting this information together in a timely manner.”Dr. Marc Judson of Albany Medical Center and co-investigator of the study added the following comment: “Although more sarcoidosis patients need to participate in this survey to reach definite conclusions, these preliminary results are reassuring. These data show no obvious signal of a particularly poor outcome from COVID-19 infection in sarcoidosis patients. Furthermore, these preliminary results do not suggest that steroids or other immunosuppressive medications are placing sarcoidosis patient at a greater risk of a poor outcome. This has been an important undertaking by the FSR.”This study is ongoing and we need more information now.https://www.stopsarcoidosis.org/coronavirus/Other interesting links:Cycling with Sarcoidosis http://carlinthecyclist.com/category/cycling-with-sarcoidosis/The Foundation for Sarcoidosis Research https://www.stopsarcoidosis.org/FSR Summits 2020  https://www.stopsarcoidosis.org/patient-summits/Donate to my KISS (Kick In to Stop Sarcoidosis) fund for FSR  https://stopsarcoidosis.rallybound.org/JohnCarlinVsSarcoidosis?fbclid=IwAR1g2ap1i1NCp6bQOYEFwOELdNEeclFmmLLcQQOQX_Awub1oe9bcEjK9P1EMy story on Television https://www.stopsarcoidosis.org/news-anchor-sarcoidosis/email me  sarcfighter@gmail.comSarc Fighter Facebook Page  https://www.facebook.com/SarcFighter/

Crohn's Fitness Food
Ryanne Sullivan, Crohn's Warrior finding remission through diet and lifestyle (E56)

Crohn's Fitness Food

Play Episode Listen Later May 4, 2020 46:15


In today’s episode, Ryanne Sullivan, shares her 20-year journey with IBD. Diagnosed with both Crohn’s Disease and Ulcerative Colitis, she’s learned to manage her symptoms and achieve remission through nutrition and lifestyle. At age 14, she started treatment with medications, like many others, using steroids and 6MP to try and control inflammation and symptoms. But, she often found the side effects of medications to be worse than the IBD itself.  Over the years, Ryanne has found stress to be a major trigger of her flare ups. Right out of high school she started working full time and living on her own, but the stress brought on yet another flare. Remicade helped to put her back into remission, however, it was short lived and soon after she was back to battling Crohn’s symptoms.  After the Remicade failed, her aunt introduced her to “The Maker’s Diet” by Jordan S. Rubin. It focused on bringing nutrition back to the basics of real food, grown in nutrient-dense soil and improving the microbiome. The book kicked off her journey to discovering how she could control inflammation from within. Since then, Ryanne has only had a few flare ups due to the stress from each of her three pregnancies and with the knowledge and experience she’s gained over the years (and continues to gain!), she was able to get right back into remission.  Ryanne focuses her diet around foods and supplements that help reduce inflammation, including plenty of fruits and vegetables and grass-fed meats. Her family eats the same and follows a healthy lifestyle with her, though she does try to let her kids be kids and enjoy the occasional bowl of ice cream and Goldfish crackers :) She’s learned to listen to her body and knows what the first signs of a flare up are for her, which gives her a chance to head off a full-blown flare up by sticking to the basics and giving her gut a chance to heal. Her go-to methods and supplements include intermittent fasting/gut rest, aloe vera capsules (or juice), Protandim® Nrf2 and Nrf1, prebiotics and probiotics, easy-to digest foods and soups, golden milk (made with almond milk, turmeric, black pepper, ginger, and cinnamon), and dandelion tea. As many of us with Crohn’s Disease and Ulcerative Colitis know, genetics play a role in IBD. Recently, Ryanne’s 8-year-old daughter was diagnosed with Crohn’s and they’re working together to help give her the same level of control and quality of health. Ryanne talks about what it was like to have open and honest conversations about taking a holistic route with her daughter’s pediatrician and gastroenterologist. While medications are not off the table, they are hoping to avoid them. Ryanne’s advice for other parents with children diagnosed with IBD: keep a food journal, learn everything you can about the disease, learn to talk to doctors openly, and  get involved in the community! To keep up with Ryanne and her IBD journey, follow her on Instagram at:https://www.instagram.com/ryanne_sullivan/  

Between Two Derms
05 - Psoriasis treatment with Dr. Cory Rubin

Between Two Derms

Play Episode Listen Later Apr 27, 2020 33:47


Cory Rubin is a Board-Certified Dermatologist practicing at the Michigan Dermatology Institute in Waterford, Michigan. He is the founder and medical director of the practice, and is on staff with several large health systems in Michigan including Ascension/St John-Providence, Beaumont-Royal Oak, DMC Huron Valley-Sinai, McLaren-Oakland and St Joseph-Oakland hospitals. His medical school education was completed at Thomas Jefferson University in Philadelphia and his dermatology residency training was performed at the University of Michigan in Ann Arbor. He has a passion for complex medical dermatology and professional skin care. When not practicing, he is a proud father, happy husband and avid ice hockey player. Instagram links https://www.instagram.com/@208SkinDoc https://www.instagram.com/@treasurevalleyderm https://www.instagram.com/@michiganderminstitute If you think you may have psoriasis and would like to seek out a dermatologist in your area please visit https://find-a-derm.aad.org/ to locate a board certified dermatologist in your area.  For additional resources for patients with psoriais please visit https://www.psoriasis.org/ or https://dermatologyboise.com/What-We-Treat/Psoriasis Oral medications discussed included methotrexate as well as Otezla https://www.otezla.com/ The biologic injectable medications we discussed are listed here as well according to their class, and otherwise in no particular order.  TNF-inhibitors Humira https://www.humira.com/ Enbrel https://www.enbrel.com/ Cimzia https://www.cimzia.com/ Remicade https://www.remicade.com/ IL-17 inhibitors/receptor blockers Cosentyx https://www.cosentyx.com/ Taltz https://www.taltz.com/ Siliq https://www.siliq.com/ IL-23 inhibitors Ilumya https://www.ilumya.com/ Tremfya https://www.tremfya.com/ Skyrizi https://www.skyrizi.com/ IL-12/23 inhibitor Stelara https://www.stelarainfo.com/ If you have found this information helpful please consider leaving us a 5-star review on Apple Podcasts or wherever you get your podcasts.

Crohn's Fitness Food
Yovani Gonzalez, Crohn's Warrior and founder of Purple Roots Clothing (E54)

Crohn's Fitness Food

Play Episode Listen Later Mar 16, 2020 58:05


In today’s episode, Yovani Gonzalez shares his IBD journey from rapid onset and diagnosis to turning down surgery and finding the right balance of medication, diet, and lifestyle changes to take back his health. Before Yovani’s diagnosis, he was an active 26 year old working 12-hour shifts, hitting the gym hard, and enjoying everything in life–including great food and watching the game with a beer. But when he had his first sudden flare up and immediate Crohn’s diagnosis, his life turned upside down. Steroids helped with the initial inflammation and then he started Remicade treatments. But his mindset was one of “let’s take a drug to fix this and go on with my life.” Young and stubborn, as he described himself, he wasn’t ready to make any lifestyle changes. But, Remicade eventually lost its effectiveness and he found himself back in the hospital. He switched medications to Entyvio and later to Humira. At the end of 2017 and beginning of 2018, Yovani faced his worst years yet. His weight dropped from around 170 lbs. to 138 lbs. and it was then that he decided he needed to do more than just take medications. Yovani took a look at all areas of his life and with the support of his friends, family, and girlfriend (now fiancé), he made some significant changes. He took a new role at work that was less stressful, he began changing his diet and workout routine, and sought the help of a holistic doctor. Yovani focused his workouts on endurance and started incorporating new activities, including yoga, which helped him slow down both physically and mentally. He focused on sleep and changed his priorities–allowing him to focus on his health. For his diet, he gave up beer (though he still has an occasional glass of wine or cocktail), learned what he tolerated and what he didn’t, and adopted the Autoimmune Paleo diet as his way of eating. Over the years, he’s kept his positive outlook and tends to look at new hurdles as challenges that he can take on and overcome. He adapts to what life throws his way, looks at problems from new angles, and is grateful for the support of his friends and family around him. One of the biggest life changes that Yovani and his girlfriend recently made was moving to Palm Springs. With long-term health as their focus, they wanted a quieter place that would allow them to be outdoors more with less traffic and stress. Throughout his journey, Yovani has always kept a focus on his roots–what drives him and what anchors him. His focus on remaining true to his roots, combined with a passion for clothing and fashion, led him to start Purple Roots Clothing just over a year ago. His line is focused on clothing for active lifestyles that raises awareness and supports a cause (Crohn’s and Colitis Foundation), while at the same time being approachable and wearable by anyone–not just those with IBD. Purple Roots Clothing is about finding your roots–your anchors in life–and remaining true to those. Follow Yovani & Purple Roots Clothing:https://www.instagram.com/crohns_fit_yo/ https://www.instagram.com/purple_roots_clothing/ ---Episode support:Intestinal Fortitude Supplements: https://www.crohnsfitnessfood.com/if (10% OFF use code CFF10)

The Axial Spondyloarthritis Podcast
An Open Letter to Family and Friends

The Axial Spondyloarthritis Podcast

Play Episode Listen Later Mar 15, 2020 11:49


Hello, and welcome to this episode of The Ankylosing Spondylitis Podcast. It's so great to be here. As I record this sitting in my apartment it's March of 2020 and it's about 55 degrees outside here in Michigan. So I know that's not warm to many of you, but for this winter, it just tells us that now we're starting to head into spring and the warm weather is on its way and man that just makes me so happy.  I received another review for the show and I just wanted to read. It is a five star review from the podchaser.com website. And if you ever want to leave a review for the show, if you're inclined, go to podchaser.com. You can find my show The Ankylosing Spondylitis Podcast and then go ahead and leave a review for it. So anyway, this review is from Liquid Soap and it says: Awesome, simply very humane and informative. I love it. I'm glad they're happy with the show. Glad you're happy with the show. I'm glad you're listening. And it's great to have you here today.  I want to touch base on something that I read on one of the forums. It's the form called Living with Ankylosing Spondylitis and you can find that on Facebook. This was a posting done by Angela Coplin Robinson back on October 21st of 2019. I finally connected with her and she said it was great to review this. So I've wanted to review this for a while and it really, I think goes to the whole core of everything that we all think of with Ankylosing Spondylitis. I want to just read this because it's so powerful the way she wrote it. I don't think that there's anything really that needs to be changed because it's just, in my opinion, perfect. So I want to read it, and then add my commentary in certain spots, and at the end of it, and I hope this just really resonates with everyone listening because I just think this is perfect. In fact, Angela originally posted this message to her family and friends, and she writes: Tired of walking on eggshells around certain people. This will be quite a long post, but I want my family and friends to know a few things.  1.    I love each and every one of you. I might not go see everyone all the time. But I am battling a disease that sometimes controls everything in my life. When I'm in a flare, I don't venture out and these last few weeks have been hard. Now I'm coming out of one and feeling less defeated.  2.    I do everything in my own time. I clean the house, cook and do normal everyday things when I have less pain and more energy. If you walk into my home and see that it's not pristine. I'm probably in a flare. You all know I love a clean home and believe like modded a place for everything and everything in its place.  3.    My memory is shit. If I say I will meet you or call you back, you can  remind me the day before or morning up. I forget words sometimes and stumble around in my own mind. Please help me remember, I do have a tablet that I write things down on if I remember to look at it  4.    When I tell you that I'm in such pain that I wish God would take me, it doesn't mean that I'm suicidal. I love life and I want to live my best life to see my kids, grandkids, nieces, nephews grow up. Just in those days. I can't see past some of this debilitating pain. Not all days are bad, though.  5.    I hate saying that I'm hurting all the time. So when you ask me how I'm feeling, I may just lie to not be complaining. I heard every single day, but it's a controlled pain. Only during times of flare, I'm in massive pain.  6.    I'm sick of doctors needles, prescriptions, and this disease period. I am trying Remicade infusion therapies on Wednesdays to try and stop the process of ALS or at least slow it down. He'll be tired for a few days afterwards. At the least, this is my last ditch effort to help myself. Please don't tell me my decision Support this podcast

Gut Check Project
Crohn's: Living Life to the Fullest

Gut Check Project

Play Episode Listen Later Feb 13, 2020 61:46


Although Dr Brown is a real doctor, the Gut Check project is here to inform, discuss and most of all have fun. The show is not intended to diagnose or treat anything. So if you have a new mole, grew and extra toe, and cant figure out that weird rash, we recommend that you go get checked out by your healthcare provider. So sit back , free your mind, and get ready to think and step into the gut check project.Eric Rieger  Alright guys, here the gut check project. It is now Episode 32. We have an incredible show today if you've ever suffered from ulcerative colitis, Crohn's disease, or anybody that you know has ever dealt with an IBD and inflammatory bowel Disease this show is going to be incredible. We have a special guest today and let's knock off a couple of our sponsors for today we have Atrantil, you can get your own Atrantil at lovemytummy.com chock full of all natural polyphenols you will not find a more comprehensive natural collection of polyphenols to address your bloating, your IBS symptoms etc Dr. Brown you know a little bit about Atrantil.Ken Brown  I know a little bit about it and you know what I want to do to offer everybody you said lovemytummy.com  I'm going to add a little something if you want your beneficial policy and also we're going to get into that with inflammatory bowel disease Crohn's ulcerative colitis, just put /KBMD you'll save some money.Eric Rieger  Save some money go to love my tummy calm /KBMD Dr. Brown is exactly right. Treat yourself treat your gut treat your life Atrantil your bloating relief, it's what they do. Second thing of course here at KBMD health we have the gut check project at KBMD health we also have KBMD CBD and you can go to KBMD health.com and find your own physician vetted co2 all natural extracted, coa of everything that comes out and basically anything that you want out of a CBD we've got Dr. Brown Ken Brown  Well the thing is is that everybody's kind of buzzing about CBD and I know even the Crohn's and colitis community people are talking about it but it's been studies have shown that over 80% of the CBD that people grab, don't have anything that is actually on the label. And what that means is you don't really take anything or you could be taking olive oil or whatever. Time and time again today today we treated people this morning and they said wow, I was on like three different CBDs and when we started the kBm the health CBD I'm actually noticing somethingEric Rieger  Happens all the time. So if you want reputable CBD, used clinically by gastroenterologist, check out KBMDhealth.com. Get your own CBD today and use code GCP to save 20% on your purchase Ken Brown  20% Eric Rieger  20% Next, our final sponsor of today's show is going to be unrefined bakery. If you want to get gluten free keto friendly paleo vegan, they've got it if you've ever wondered I need to adhere to a special diet and I'm afraid that the food's gonna taste bad guess what unrefined bakery makes great food get just so happens to fit your special dietKen Brown  You know it's nuts every patient that we had this morningEric Rieger  Yeah Ken Brown  Knows of Ann & Taylor Eric Rieger  They definitely do Ken Brown  They love them like these like they are true celebrities watch that episode. It is awesome unrefined bakery, gluten free. They can do all the other stuff just watch a show it's it's fun Eric Rieger  Based here in the Dallas Fort Worth area you do not have to live here to get your own unrefined bakery goods. You can actually go to unrefinedbakery.com use code gut check, and you can have yourself some 20% off I believe on your first order and then right 20% off anyhow unrefined bakery. com use code Check, save some money on your first order. So make it a big one,Ken Brown  One impromptu sponsor.. and just keep watching the rest of the show to figure out why.Eric Rieger  YesKen Brown  If you are a reader and you enjoy novels, go look at a book called in the end written by Dr. Michael Weisberg. In the end. He is an honorary sponsor of this show and for reasons that you will soon see later on.Eric Rieger  Yes, absolutely. As I hinted at before we got to the sponsors. This is a dedicated show to ulcerative colitis and Crohn's. And we're going to be visiting with a special someone who will tell us a little bit about her story, her journey, hopefully to relate to anybody that either yourself or a loved one on what it's like to face these kinds of challenges, but Weisberg is a fantastic supporter of the ulcerative colitis and Crohn's foundation. He knows a lot and he's, it's awesome. And he has a book like that available. So ..Ken Brown  In the end Eric Rieger  In the endKen Brown  Honorary sponsor.Eric Rieger  All right, let's start The project. So now we just wait a little bit and then we're just gonna start talking. And I don't want to mispronounce your last name. Okay. Okay. eyeball 321Eric Rieger  All right, we are here on the gut check project. It is now episode number 32. I am here today with your normal host, Dr. Kenneth Brown, and we've got a special guest. Paneez Kahkpour. Oh, you know what we had her and now she can talk.Paneez Kahkpour  Am I back? Hello Everyone. Nice to see y'all.Ken Brown  Well Paneez has been my patient for over 12 years. What do we have 14 something like that.Eric Rieger  Awesome. Thank you so much for coming Dr. Brown. You have a monikor for her already that you just annoyed her with. What is that?Paneez Kahkpour  12-13Ken Brown   Something like that I've always referred to her as the Persian princess. And so she is the she's Dallas's own Persian princess to the end here to the Persian community. This represents you My life the Persian princess. So sweet. She went to Iran of what about three years ago and brought me back a hand painted? What was that? It was art, but it told a story.Paneez Kahkpour  Yeah, it was. I'm trying to remember what it was. I'm pretty sure it was. Maybe it's like an old fairy tale. It's like a couple. I think it's called Laylee Imagine. I think it's their story, and it's the picture of them.Ken Brown  Wow. So.. really beautiful. I took a picture of it and send it to my friend Reza, who's who's a gastroenterologist in Florida, whose Persian also and he goes that's that's really expensive. Be very careful with it was like,Oh, okay. Eric Rieger  You're hanging out the window of your car.Ken Brown  Using it as a fly swatterEric Rieger  Trying to direct traffic in Denver. Ken Brown  Yeah I was. Let's go over here. These Atrantil ads Don't stick on it at all.Eric Rieger  So you've had Crohn's Correct, yes. For how long? Paneez Kahkpour  16 yearsEric Rieger  16 years, you've been a Crohn's patient. And today, I think that what we really want to do is get your perspective on what it was like to be diagnosed to learn about what it was. What led you to go seek help in the first place? So back at the clock a little bit. And what did you first experience that drove you to go? In fact, you didn't go to Ken first you went to another gasterologist.Paneez Kahkpour  I was. I saw pediatric gi doctor in the beginning, I was 15 at the time, all right. Yeah, I just had all the symptoms. I couldn't eat anything anymore. I was just constantly going to the restroom. And every time I went to a doctor or you know, General doctor, they said I had the flu. They'd give me antibiotics. Send me on my way. A couple days later, I'd be feeling terrible again. And that lasted several months. I went to the ER multiple times to get IVs, but nothing seemed to help. It was it wasn't until it was probably my like sixth or seventh ER visit and my grandma was like, You're not going anywhere you need to stay here. Someone needs to see you. I called an old pediatrician of mine. His name was Dr. Shams and he ended up. I gave him the symptoms over the phone and he said, I think I know what you may have. Let me call in a specialist. I was hospitalized at medical city Plano and then did a colonoscopy. And here we are. Eric Rieger  lLet me ask you. So you said you're 15 .. So freshman high school.Paneez Kahkpour  I yeah, I that would be freshmenEric Rieger  So as a freshman in high school going through this, I mean, your peers that age adolescence, what is it like trying to navigate that you internally you already know that you don't feel normal? So what were you having to do to?Paneez Kahkpour  I wasn't ever eating lunch. I you know, everyone thought Something's wrong with her because she's not eating. And at that time, you know, it's something super embarrassing. You don't know what's happening with you. And so it's not something I really talked about. Just because I, I didn't know it was happening, and I didn't have anyone to really talk to at the time. And it wasn't until I was diagnosed. You know, when someone finds out you have something they know a friend of a friend. And I ended up speaking to a girl who was also someone who has Crohn's disease, and she really helped guide me kind of through the initial process of everything, and it was very, very helpful.Eric Rieger  Wow. So when once you found her and so at this point, you probably found her after you've been officially diagnosed. Yes, correct. Yes. So what was it like? I mean that it doesn't sound like it, looking back 16 years, but there's probably at the time seemed like an eternity of not knowing Paneez Kahkpour  Oh, yeah. Eric Rieger  So what was that like?Unknown Speaker  And it was, it was very hard. You know, when you're young, all your friends are doing all these fun extracurricular activities and you just don't have the energy Because I just, you know, was constantly sick. It was very difficult, and very, very lonely. Even though I had someone who had some experience, it was still it was just that one person who wasn't who didn't even live here. So it was pretty difficult. Ken Brown  You said a word right there that I think this resonates with a lot of my patients, you felt very lonely. The Psychology of a disease like this is unimaginable for you. And for your loved ones. Would you just describe the loneliness a little bit? Paneez Kahkpour  You know your entire family, the ones who know and who really understand are there for you, but I mean, they only know so much. They can only help so much because they can only empathize to a certain degree. And so, you know, when you just don't have anyone to talk to it feels really difficult to try to even begin like know where to begin and who were to go who to talk to, but I was able to find some people And find my way through the Crohn's and colitis foundation that took me a few years to even find I had no idea about it. No one told me anything. Ken Brown  Why did it take so long to find the Crohn's or colitis foundation?Paneez Kahkpour  You know, I just don't know if it was back then it was still something super new, you know, no one really talked about it, it. It's even still now it there's a stigma. It's, it's embarrassing. It's gross. So no one really talks about it. But it took me several years until I knew that there was such a thing as the Crohn's and colitis foundation. But after it took me a lot of googling, lots of lots of googling until I was able to find it.Eric Rieger  So but leading up to that you you get this diagnosis and as you're trying to educate yourself and you haven't found the foundation yet. What type of changes did your pediatric gastroenterologist ask for you to make? What were you? Did you have difficulty with compliance? What was it like to step out of there and say I've got this diagnosis and now kind of have an idea of what I'm going to do. What How'd you handle that?Paneez Kahkpour  I mean, it was hard. You're 15 and you, you know, don't, you're not usually on some type of regimen. You just kind of live your life as normal as can be. But when with this change, I was taking 15 pills a day, when I was barely even taking a Tylenol before that, you know, I struggled taking pills. And then yeah, he just told me I had to, you know, watch what I eat, see what my triggers are. Beyond this, you know, diet of pills, you know, it's pretty much I was what I was consuming and so my entire day was spent taking medication and so I didn't really have time to have friends really go out and do anything because I was at home taking medication or going to bed.Ken Brown  I it's it's weird because I smile when you say this because I've seen you progress over these years and become this and tremendous advocate, super. I mean, healthy you you radiate this energy right now. And that is to bring so much hope to a parent that has a child who was recently diagnosed. And that's what I want this episode to be about your story. What I love hearing the questions that Eric is asking you are the wait a minute What is this because as a gastroenterologist, and this is probably what you experienced, it's like, Look, this is your disease. It's either 5% no seniors all sort of, these are our options. Where do we go from here? He's asking life questions. He has an 18 year old and a 16 year old. Yeah, it's Max 16 Eric Rieger  Eh two weeksKen Brown  Two weeks Okay, it's getting real close. So he's asking it as a parent Yeah, well what happened this and that. I'm listening to this and I'm like, I asked it as a clinician. So I always keep going, I love I love where you go with this.I love it love it Paneez Kahkpour  It took me many years to get here. It was definitely a bumpy road and I had lots of highs high and low moments. But you know, right now I consider it being a really high moment. I feel good. I'm in a good place. But you know, with all the struggles goals and all the things I had to get through with, you know, taking medication every day having to be doing IVs every six weeks like that was insane like, what 15 year old does that you know like that's it was a whole new territory. Eric Rieger  So making a change. You talked about that he said, watch what you eat and pay attention to your triggers. My wife was recently diagnosed with celiac disease and for her there's, there's an interface, right? We used to enjoy just sipping on a cold beer every now and then that and that's gone. So that's not the end of the world. But the changes obviously for her are more stark when you family gets together or you want to go on a road trip. There's just certain things that were cut out what was it like to you to discover? These are my trigger foods? These are the things I can't do. I've got my circle of friends that may or may not fully understand what I'm dealing with. How did you integrate back to I've got at some point you're gonna get a crossroads I gotta get my social life back in.Paneez Kahkpour  Right. Eric Rieger  So what did you do?Paneez Kahkpour  Well, first I educated all my friends. That's the big step because if they don't know what you're going through, if they don't understand what the disease is and they have Zero empathy for you. They don't really understand Ken Brown  What did you say to them?Paneez Kahkpour  Well, I have Crohn's disease and they look at me guys go cross, like what is that? I'm like, well, you know, it's a digestive disease. I try to use words as simple as I can for them to understand. I'm like, basically, I can't eat lots of things because my body rejects it. And half the time I say, if you want to know more, just go Google it because I don't want to get into the nitty gritty, all the things I just go look it up. But that that helped. And then finding out which friends were, you know, there for you and which friends were not that was really helpful. And then with diet changes, and just lifestyle changes, I had to I learned that had to be present for the things that could be present for and if I couldn't, then I had to listen to my body and say no, and really just crossing my fingers and hoping that my my friends would be empathetic to thatEric Rieger  So for Paneez. Think about the ones Small advantage that she did have was turning her friends to Google. Because think of someone just a decade before that having this type of disease trying to share that experience with their new diagnosis with their friends, like, go to the library and look whatever up if you can. And thats just not going to happen.Ken Brown  As an adult doctor, I have the advantage of sitting down with somebody that has either been handed off to me by our pediatric doctors .. had has some incredible ones in that Whitney Kendall Brown, john Baker, jack and they've got incredible doctors. So I get the pre prepared family. And now at this stage of my career, my patients are their, their children are starting to show up we're seeing more of this disease. So when I said you have what did you say because I don't know how much to vomit on somebody. Paneez Kahkpour  Yeah. Ken Brown  And well, quite honestly, when I met you when you came into the hospital as a flare And the only thing I was thinking back on my Paneez on and she'd been my patient for a long time. And you're an incredible patient, you do everything that you're that you're supposed to do, and you're an advocate, we're going to get into all of that about how you've been giving back, and how important people like you are coming on the show and doing this and being part of the Crohns Colitis society. I remember one thing I remember your mom crying. That's all I remember about the whole impatient experience, because it was too much. Eric Rieger  Well, maybe, maybe she maybe your mom was curious about the challenges it was going to be to you. And I'm going to ask you about that in a second. But the second, the second thing I was kind of curious about that may lead into why her mom would would cry because I think that that's anybody cares for the kids going to be upset. But what was it that the physician said would happen? If you didn't make these appropriate changes? And know what, what did you begin to learn the risks would be if you didn't become a compliant patient, because at some point, for some patients, it doesn't matter. They just kind of like I don't really care. I'm just gonna keep living and yeah suffer the consequences. That's not the route that you took. So what did you hear that made you decide? I'm gonna do this.Paneez Kahkpour  It was mainly how I felt. I didn't want to feel terrible anymore. I was very tired. I was sick and tired of being sick and tired. You know, that's what I remember telling myself when I was really young, as I'm tired of feeling this way. And my doctors at the time, they just said, Listen, if you're not going to do this, you're not going to get better. You're just going to get worse. You're going to have to have surgeries, you're going to have to do all these other things. And mainly, the surgery is what really scared me. Especially being so young, because most people don't have to go through that stuff. But it was mainly just really not wanting to feel that way anymore. And I must say there was a period of my time where I wasn't compliant. And that's when I met you. And that was really what changed everything for me is because a doctor changed my medication. And I didn't really take it because it was a pill. I was on IV before and then it changed. And I got super sick and I was in the big, big flares when I met you. And after that, I was like, I never want to feel like this again, like it was not worth it.Eric Rieger  Was the risk of a collective mean or anything else like that kind of on your radar? Did you think that that might ever happened to you? Paneez Kahkpour  Thats always in there like the backburner. I always think that like in the back of my mind, like there's always a chance for all of that. Eric Rieger  Sure.Ken Brown  Yeah. So let's, for everybody else that's listening this not familiar that. I mean, our audience is getting pretty broad right now. And for those people that don't know what Crohn's is, that's why I wanted to say, what did you tell your friends what Crohn's is? And you said, I couldn't eat certain things. Paneez Kahkpour  Right. Ken Brown  Let me rephrase it now that you're, you've had it for a few years. What would you tell people what Crohn's is?Paneez Kahkpour  I would just say it's a digestive disease is an autoimmune disease. And so basically, my body doesn't know what's happening. So it's attacking itself. And with that comes all these terrible side effects.Eric Rieger  Yeah. Ken Brown  That pretty much sums it up. Eric Rieger  Yeah, definitely. Ken Brown  That is beautiful, everybody Makes it too complex that So you went from. I'm talking so what you are gifted with is the ability to understand what your peer will will will hear which is I can't say automated. I can't say all this. I'm just going to say what I struggle with as a doctor is how much do you want to hear about this? Right? So when you were 15, you said like, the bottom line is I just can't eat certain things, and I may get sick. Now you're like, Look, here's the deal. Yeah, my body's attacking my own intestines. That's what Crohn's is. We're gonna leave it at that.Eric Rieger  Yeah, definitely. So do you want to get into to mom? Because this is something that just for the audience, this is something before you even got here Paneez that came was like, the thing I never forgot is how resilient Paneez was and how much your mom apparently and I've never met her but was concerned about your future.Ken Brown  So we each every single episode regrow and we we find new ways we find new science and I become a better doctor because of it. I mean Eric sees the patients he puts them all to sleep. And when I asked you to come on the show is because of the emotional aspect of being a parent. It wasn't so much that you because you're amazing. I mean, like you persevered and we're going to get to the Oasis camp where you've been a counselor, we're going to get to the fact that you're a speech pathologist for underprivileged autistic kids with so you are up here. I just always thought, did your mom know you were going to do that when you were diagnosed? Paneez Kahkpour  You know? I don't think so. I mean, you have all the hopes but there was a time where the disease was all that I was and that very much defined defined me and my life. And I think that was a big struggle for her. Because you never want to see your child sick and in a hospital bed with hooked up to all these wires and IVs. And that's just a terrible site. She struggled a lot. My entire family did. My grandmother, my brother, my dad, but a lot my mom because she was my main caretaker, she was there for every step of the way. But I don't think she ever thought that I'd be doing all these great things and being, you know, self sufficient.Ken Brown  It's a story of perseverance. It's a story of giving back. It's a story of sharing and caring and doing this kind of thing. It's so we were at the Crohn's and colitis annual gala, where my partner, Dr. Mike Weisberg was being honored as Person of the Year and gave an incredible touching speech, or keynote speech, I should say, where I thought it was just I mean, I admire public speaking, because just like you're doing right now, being on a mic is not so easy sometimes, but you're crushing it.Eric Rieger  Well, not only is he a gastroenterologist, didn't he? Didn't you tell me once before that his one of his kiddos has RBD of some kind?Ken Brown  Yes. So leading it up to this, and I want to ask a favor of you Paneez because it's going to take a few minutes. So I actually called Dr. Weisberg Dr. Mike winesburg last night and I said, Hey, I'm gonna bring a Crohn's patient on and I know that your son had Crohn's because you discussed it in your keynote speech. And I'll tell you what, I've worked with him for 17 years, and I had no idea this was going on. And so it was like, it's like the duck with the, with the flippers, right? You got to keep your game face on go to work, just like you've probably done a million times. Yep. You feel like, you know what, and you're Paneez Kahkpour  Pushing through Ken Brown  Push through. I got to tell you that. I'm just a quick side note, before we get back to that really quick. Crohn's patients. I have to tell them that they're sick. They're like, No, no, no, I'm good. I've been worse, i've been worse. They're tough as nails like Crohn's people just like at some point, they just start sucking it up and they're like, No, I'm just gonna deal. Screw you. I'm not I feel sick, but I'm sick of being sick.Paneez Kahkpour  Yeah, you've done that to me. Actually, beforeKen Brown  I have. I keep trying to make her sicker than what she is. I'm like your bloodwork.Paneez Kahkpour  I know I remember one time I was I was very, is during my second flare and I came in to see you. You had my bloodwork and I was, you know, I dressed up for the day trying to make myself feel good. You know, if you look good, you feel good type of thing. And you made me walk to the emergency to the hospital and it put a gown on because you're like, you're very sick. I didn't know it because I was like, I'm fine. I'm strong. I got this. And I wasn't.Ken Brown  So when I called Mike last night, I was I just wanted like, hey, what was it like being the parent of Crohn's patient and so as it so happens, Dr. Weisberg, whom I admire very much, he's been my partner for years he was awarded Person of the Year for the Crohn's and colitis society. He is also an award winning author of two novels, the hospitalist and in the end that we discussed as an honorary and rather than just sit there and throw, you know, two lines Oh, it's it's tough being a parent of a..wrote a little bit and if you guys would humor me, give me just about five minutes. This experience is something that I want every parent to share. If you have a sick kid, I would like people to realize, because what he showed here and he just wrote this in an email, and I read it this morning and I went, holy cow, so you wrote it last night. So I'm going to read it. And this is from Dr. Weisberg verbatim no changes Eric Rieger  All right.Ken Brown  When I think back 13 years to when my son Reed was diagnosed with Crohn's disease, my mind flooded with vivid scenes and emotions. I will try to relate some of them to you in the next few minutes. Reed had never been a very active child. He was never one to ask to go out to play football or ride his bike. We just assumed that he was a laid back kid, a cerebral kid who enjoyed playing on the computer and playing video games more. At age 12. We decided To send him to sleepaway camp, which is not Oasis, a traditional camp sleepaway camp for a month over the summer, along with his nine year old brother Brent, in order to go, Reed had to have a camp physical, which my wife and I thought was routine. I was working that night when my wife called me and told me that the physical exam revealed that Reed hadn't grown an inch in the past year, and had actually lost two pounds. Plus bloodwork showed that he was severely anemic. I felt guilty that I had not thought of this as a cause of Reeds easy fatigue ability and avoidance of strenuous activity. But as I thought about it more I realized that night that Reed may have Crohn's disease. I had suffered from a related disease called Iritis, which is Crohn's disease of the eyes. And my sister had been diagnosed with Crohn's several years before. I knew that chromes presented and reads it Group and that all his symptoms fit this diagnosis at 730. That night I drove frantically to the pediatricians office wanting answers and I pounded on the doors of the locked offices for 20 minutes until I realized that it was futile. Since I was a gastroenterologist treating Crohn's patients, I knew what a devastating disease it was. And I became terrified. When I got home that night, I personally examine Reed and found that he had an anal fissure, which he hadn't told anyone. He'd been having rectal bleeding read younger brother went to summer camp alone that summer because Reed was too sick to go. My wife was too upset to drive Brent to the airport, so she stayed at home with read while I drove Brent and dodged all the other parents questions about why Reed wasn't going. I met my wife in a park in between our home and office one day at lunchtime, and we just sat talked, held hands and cried. We had no idea how extensive and severe Reed's disease was. But as his parents, we felt so sad for him and what he had been going through and what the future would entail. I personally felt tremendous guilt. I felt that I had given my son this disease and it was my fault that he was sick. I talked to my wife and several friends who told me that if I took all the blame for Reed's illness that I must also take all the credit for his admirable traits, such as his intelligence, his sense of humor, and his willingness to work hard to achieve things. For a very long time. These arguments did nothing to assuage my guilt, and it was only after Reed felt better that I quit being so hard on myself. We took Reed gastroenterologist who did his colonoscopy while I stood in the endoscopy room watching, I saw all the damage the Crohns said done to Reed's intestines on the telly Vision screen as a scope made its way around the colon. Afterwards, I had to go to work and even though I felt depressed and upset and guilty, I never missed a day of work or miss treating a patient due to my grief. Reed was started on enamoran and we waited for him to get better.Ken Brown  Instead of getting better Reed worsened and he had more fatigue and high fevers his liver test went through the roof the Emoran was stopped just as we left for a family reunion on Amelia Island in Florida. I talked to his gastroenterologist the night before we left and he told me it was okay for Reed to go, but to take him to the hospital first for two sets of blood cultures. I drove Reed at tea at 10pm to my hospital and had blood cultures done. The trip to Amelia Island was a disaster. Reed was sick had high fevers the whole time, and I finally found a doctor in the box where they were willing to give him some antibiotics. Reed love to fish but the day of our deep sea fishing trip he was sick the entire time he lay in the boats cabin and vomited into a pail where he lay. I could go on with memories forever overall, until we took read to see Marla Dubinsky and IBD expert Los Angeles. He was constantly sick with pain, fever, diarrhea and anemia. Marla did testing put them on Remicade, which he took for six months until developing an anaphylactic reaction. I was scoping at the time that he had this in the same building I was so I had to run and see my son go through an anaphylaxis reaction. I had Remicade stopped and Dr. Dubinsky switched into humera, which he was on along with methotrexate for 12 years. He stopped the methotrexate last year and is now only on humera shots every two weeks. It was hard giving my son a shot every two weeks, but he was so brave and never once complained. I could tell you that I felt depressed devastated and guilty, and that the light in my life had been turned off. That is until Reed started getting better. Boy did he ever he started to grow and gain weight started having a physique that resembled his classmates instead of a skeleton. He went into remission grew to a normal height and weight. This summer he will graduate from medical school and start a residency in internal medicine. I am extremely proud of all he has accomplished but even more proud of the person he is. He never complained, never cried why me, but instead has met each challenge head on, and fought until he won. When I asked him why he wanted to be a doctor. He told me that he wanted to be like me and help make people better. He wanted to be a healer. The light in my life is back on and I am certain that I will be alive the day, a cure for the diseases is found an impromptu thought by Dr. Michael Weisberg when I just said What's it like being the parent of a Crohn's kid? Eric Rieger  What why so short? Why no detail?Ken Brown   There's a reason why his books are so good.Eric Rieger  Now seriously, Dr. Weisberg, thank you so much for the submission that's it that's an incredible story. Paneez Kahkpour  Yeah. Eric Rieger  How do you think your your mom would relate to that?Paneez Kahkpour  100% like the feeling of guilt I think that my mom and my father felt that for many years and I still think they sometimes do still to this day you know, I don't think that ever really goes away. But yeah, the the guilt the depression just feeling helpless that you can't do anything for your child.Eric Rieger  Did your parents have to watch you try like we've seen a lot of Crohn's patients do the the drug hopping from Enamoran to Remicade to humera etc. Till you finally found some mix. It works for you and then I mean, did you did you have to endure anything like that?Paneez Kahkpour  Well, luckily, no, not really. I was on a bunch of like I was on Enamoran and all these other things when I was first diagnosed, but I was also started on Remicade, and I've pretty much been on Remicade ever since I took a year off, and that's when I met Dr. Brown because I wasn't complying with the medication I was taking, but I've been able to go back and Remicade and that's pretty much all I've ever really been on. Luckily, knock on wood.Ken Brown  One of the coolest things here is in we forget we take the burden of everything but the fact that Dr. Weisberg noted that his friends and family and his wife said, hey, there's a lot of great traits. There's a lot of great traits do. I mean, it's so hard as a parent to go I mean, except for Eric every time Gage scores, thats my son. That's me out there.Ken Brown  But it's so funny because his parents, that's what we do as parents is we just say What did I do wrong? How could I have changed something Because my child may be sick and I don't think it stops at Crohn's or colitis I think it you know anything juvenile rheumatoid arthritis. I don't want to get into the, you know the cancers and things like that everybody says what could I have done different and it was fascinating to think that it's exactly right the same characteristics that Reed, developed, or at least had all along allowed him to now he's gonna be a bass doctor, a real badass doctor, and I've met him and he's taller than me. I mean, he's a stud.Eric Rieger  I live vicariously through everyone I know.Eric Rieger  Nice.Ken Brown  Yeah, you met him at the Crohn's and colitis foundation didn't?Paneez Kahkpour  actually knew him through camp Oasis actually.Ken Brown  Oh, we need what is camp Oasis says,Paneez Kahkpour  Well, Camp Oasis is a camp for kids with IBD Crohn's disease or ulcerative colitis to come for about a week to just live like a normal kid and have fun at camp. It's probably the best thing I do in my life every year. I've been going for I think about seven years are so best time of my life.Ken Brown  I thought your doctor visits for me with the best thing?Paneez Kahkpour  No, Yeah, that's it. That's like neck and neck.Eric Rieger  So, Camp Oasis, if I remember correctly, there are 12 states that have a location that routinely host these kiddos with you see your Crohns. And then I think the one here in Texas is what outside of Bruceville?Unknown Speaker  Yeah, now it's, um, it wasn't Bruceville and now it's some place called. I'm not sure. You know, Texas, so many little town. Sure. Not really sure. But yeah, it's some it's like two hours outside of Dallas.Eric Rieger  Okay, nice. Yeah. And so, but it's directly affiliated with the Crohn's and colitis Foundation, correct? Paneez Kahkpour  Yes. Eric Rieger  And so, supporting the camp oasis. It's, you're going to have the latest research, the latest techniques, the the best, quote, unquote, training for a kiddo to learn how to deal with the situation right?Paneez Kahkpour  Well, you know, they have it's basically a week where They can feel like they are heard or noticed. They have other friends there who also have the same disease they have right. And most of the counselors who are there, not all of them but most of them also have IBD. And so it's just like everything you could possibly want in life and a week.Ken Brown  So somebody feels comfortable. They say my belly hurts that's..Paneez Kahkpour  Oh, yeah, we have a whole med staff everything like you were mentioning we have we have a whole med staff nurses, child life specialists that called everything every everything they would possibly need. They have theirEric Rieger  So would you say by attending a camp like that having this disease affliction that you began to learn? I can have a normal life.Paneez Kahkpour  YeahEric Rieger  These people are making it or I remember when I felt like that you probably serve as a mentor if you just happen to be further along than somebody.Paneez Kahkpour  Definitely. I mean, I feel I wish I went to camp as a kid. But I didn't so I'm lucky to be able to go as an adult. But yeah, they they see all these adults doing all these wonderful things like Reed going to medical school, and they see Oh, I can do that if they can do And they have the same disease I have, and they have had surgery, they've done all the things I've done, I can do the same thing. And its wonderful.Ken Brown  What was your first year like as a counselor, because it had to bring back a lot of memories of what you experienced.Unknown Speaker  I mean, it was, it was sad, in a sense, because you just see all these kids, like, I don't remember myself, you know, as a child, like dealing with all these things. We just see them and you just see how strong they are and how happy they are and how they, like you say they persevere. And I'm like, how even though I was the same, but I just, you see, and you're like, it's incredible. And every year I go I cry because some kid says something super motivating and inspirational. I'm like, I don't know if I'm doing anything for you. Because you're the one helping me like feel like I'm there to live a better life. It's all it's all them. It's really wonderful. But yeah, the first year was intimidating. I didn't know anyone. I'm meeting all these people with Crohn's and colitis, like that's super cool. But at the end of the day, you you leave with a family and we've all been together ever since.Eric Rieger  That is awesome. How many times have we heard things on this show with from guests that giving is the best getting that you can do? Ken Brown  Absolutely. Eric Rieger  I mean, it really is. Ken Brown  Absolutely. When I'm curious as there's a doctor, you said that there's a doctor that runs this every year?Paneez Kahkpour  Well, yeah. So it's, it's the Crohns and Colitis foundation sets it up, and then they have a pediatric doctor come along, just because if there's a flare if a child needs medication, we they handle all the medicine, everything. They they do it all and yeah, there's a pediatric gi who comes along and does everything.Ken Brown  Just the whole idea of just being a normal kid, and still experiencing your normal symptoms. And it's not like blown out of proportion. It's not like overreact. It's like Okay, come on over here. Let's go over. Yeah, you're not going home. We're gonna we're gonna make you feel better. Paneez Kahkpour  YeahKen Brown  That's cool.Eric Rieger  Absolutely. And you can I noticed on the website, that Most people can volunteer if they wish to. And you can donate, obviously, directly to the camp through the Crohn's and colitis foundation. So it's obviously an incredible resource for people who are young and newly diagnosed.Ken Brown  I'm going to put you on the spot. But it was there ever a time that you ever were this I'm really put you on the spot because because I think it's like a healthcare provider if I'm in a camp with people that potentially can get sick on me, you know, I'm like, worst case scenario person. So were you ever in a position where you felt that you were worried for somebody?Paneez Kahkpour  Um, yes and no, yes. Because they weren't feeling well, or they, you know, have been vomiting a lot or something, you know, because a lot, it's in the summer. So, there's a lot of heat. But no, because we haven't fully staffed with all these smart doctors and nurses who come and help the kids. So like, there was never a time where you're like, Oh, this is not going to be good because they're fine. They're in safe hands. Ken Brown  That's awesome.Eric Rieger  That is awesome. Well, what can people do if they wanted to connect with someone from Camp Oasis? And let's say that they have a child that they want to get enrolled, but they may not live close, they're a particular resource or a way for them to get in touch with counselors to do that?Paneez Kahkpour  I would say just going to the website would be the best starting point.Ken Brown  Crohn's or colitis or the Oasis?..Paneez Kahkpour  Because that will take you to the camp, website. And m depending on where you live, you can see where the closest camp is and then I think there's always an email or phone number for the director who like sets up sets it up for every state.Ken Brown  Man i'm sitting here thinking I'm just like, wow, it's, it would be really cool for like, I'm hearing this like I learned about Camp Oasis from you. Yeah. And I'm like, Oh, I I feel like like a jerk like I have not been involved sooner than that. And then I went home and talked to my kids lil bit about it. They're just like, Wow, that's great. And I'm sure that there's a lot of different camps for different illnesses.Eric Rieger   Oh, yeahKen Brown  I didn't realize that there's a lot of people giving back all over.Eric Rieger  That brings me. That brings up my next question. I'm glad you brought that up because not that far from here for juvenile diabetics, there's a place called Camp Sweeney. And when people go and that was it, I was a maintenance man there when I was in high school, but..Ken Brown  He was the janitor.Paneez Kahkpour  Come a far way.Ken Brown  She's over here going, Wow, you've come a long way. I had Crohns almost died and I'm doing this but you..Eric Rieger  I guess you got out of your truck. But the thing that I found kind of interesting is almost and I'm kind of curious if it's the same for for camp oasis. The first time that someone came to camp Sweeney, sometimes there was a chance. They were reluctant to get out. They didn't really know why they were going. They really didn't know what they were going to get out of it. They kind of had to be talked into it by their parents. And then when they got there You saw it within the first 24 hours. Oh my gosh, these are my These are my people. Yeah, they understand what I'm doing so I guess I'm just saying that for someone who may be new to camp Oasis, you have a kiddo you get them get them inoculated, get into around and to talk to someone.Eric Rieger  That's awesome.Well..Paneez Kahkpour  Yeah I mean, it's super helpful. I, I, I've seen kids who are newly diagnosed come into camp for the first time crying because they're like, I don't know anything. I don't know anyone. Like I'm super nervous. They leave crying, but not be because they're happy that they met all these friends, and that they're sad to leave, they don't want to leave. And so everyone starts crying. What are they? It's, it's the best. I mean, you know, whoever wants to apply to be a counselor. I think for the Texas camp, it's open. So come hang out. Ken Brown  Well, no, we have a whole new topic that I want to get into. Oh, yes, because I've known Paneez the Persian princess for a long time.Eric Rieger  This is..Eric has no idea what you know.Ken Brown  Yeah. And I've watched Well, she has gone on to not only be a camp Oasis, Counselor, but she's doing something which I think is fascinating. It's huge. And now we're going to talk about something else. That is a passion of mine, which is autism. Eric Rieger  Oh, yeah.Ken Brown  Yeah.Eric Rieger   So I did know that sorry.Ken Brown  Well, you give a little background about your education. And now what you're doing because if you want to talk about the one two punch of giving back, Camp Oasis, and wow, that was just the jab. Now we got the right cross coming. This is coolPaneez Kahkpour  You know, gotta do a lot. So I actually I went to University of North Texas here in Denton, wonderful school. I studied speech language pathology, pathology, audiology, so I have an undergrad degree in that. So technically, right now, I am a speech pathology assistant, but I'm working on my grad school applications at the moment.Ken Brown  You speak better than us. So you're, you're the master in this room.Eric Rieger  Thank you. Pretty good.Ken Brown  Pretty good. Speak English real good.Paneez Kahkpour  You know, lots of practice. But yeah, so I work with most of the kids I work with right now have autism. And it's it's quite a job. It's actually pretty fun.Ken Brown  But it's not just autism. It's actually autism for a lot of underprivileged kids. Paneez Kahkpour  Yes. for underprivileged kids. Ken Brown  Yeah. And so what? So So Penny's and I were talking about this, because autism, I'm a huge advocate of the gut brain access, and that if you heal the gut and you feed the gut, then it will heal the brain and we got into a discussion so you asked all those questions at the beginning of the show. What did your pediatric gastroenterologist do? What did you recommend for diet recommendations? What did he do this and that? So I'm sitting with Paneez in my office and I'm like, Oh, my gosh, that's so cool. Can you get them to go gluten free? Can you get them to go Whole Foods? And she's like, Well, let me tell them my patient population first. Yeah, has described what the typical person lifestyle is and They're, they're home life.Paneez Kahkpour  I mean, most of them are lower income. And so with that brings just difficulty and buying just healthier foods, and having access to a lot of stuff. I was talking to a parent actually, who had to take a child to the doctor, and they waited eight hours. So I'm like, they still have access to a lot of things. And so they're not eating as well as they should, or they may not be doing the things that you know, you and I have easy access to. So that's what makes a little bit harder.Ken Brown  So, a couple episodes ago, Episode 28, Doug Blonde was on here and I challenged him with the same thing he is in. He's a medical doctor that it's an advocate for whole food plant based. And I said well, the problem with that is is that when you say whole food plant based you think of going to Whole Foods and spending a lot of money. Paneez Kahkpour  Yeah. Ken Brown  And I and he told me that no, you can do it really cheap and he gave prices he discussed the price of doing lentils versus as long art..My gosh, I can go down rabbit holes on this one, our secret weapon, which we'll reveal one day he sent me some incredible articles on manufactured fibers or fibers that that are added to foods to augment the plant based diet and to do things like that and the inflammatory process that it actually causes. So if you're opening up a package mean just that means that they put stuff in there which will pause an inflammatory reaction in your body. I know that that leads to intestinal inflammation resulting in brain inflammation. So on Doug's episode, we discussed how you can buy for pennies on the dollar foods which will supply thymine, which I mean he's got the vitamins down, he's got the fiber down. So the misconception is that you can actually take a parents say don't go through the drive thru McDonald's, it seems cheap. When if you can just go to the periphery of the grocery store, it's always the periphery. It's not the middle, not the middle. Do not walk down the aisles, just walk around the outside, you'll be able to fill your cart with sustainable foods which provide most of the nutrients that you will need. And you can do it in a cost savings and it, it hurts my feelings that I mean, I feel like you're doing an uphill battle right now camp Oasis is awesome. That is like you crush it right there. Now you're going and you're helping autistic kids that when they go home, probably the parents are not educated enough or Well, nobody is it's America. Nobody's educated enough on how to properly eat.. Well I'm not I'm learning. Eric Rieger  Well think about the challenge that you said about the mom who has to wait with the kiddo for eight hours. That's a work day for her. It's a work day for the dad. I mean, they're sitting there doing that they're negotiating. I'm going We are going to have to do without because we have to go and do this. And we're going to waste all day waiting. Ken Brown  So let's go back to the parent perspective again. So now you have an autistic child that you are trying to work on their speech capability to express their emotions. And a parent shows up and says we need to pick them up. What's your interaction with the parents?Paneez Kahkpour  Um, it's not too much. It's usually like, every time I see their child, it's maybe like a four or five minute conversation. So not a whole bunch just because in that conversations is, this is what we did today. These are the things you should try to do at home and see you next time. That's basically as much as we really get because most of its spent with that child. So it'sa little hard. Ken Brown  I could just imagine what happens with somebody who is worried about paying next month's rent. Eric Rieger  Oh, yeah. Ken Brown  And they have a trial that it has some trouble communicating on the Autism Spectrum Disorder it's the the ability to become empathetic to that situation. You have that ability because you have Crohn's disease, and you have muscle through it and you chose a career which could be one of the more difficult uphill battles to change a the underprivileged autistic community. And I commend you on that. Paneez Kahkpour  Thank you.Ken Brown  That is awesome. That is it is a bold, bold thing. Definitely, but I could totally see. Man, it's a hierarchy of needs. I have a I have a patient whose they actually corrected their their child's autism but they also have the resources share the intelligence they I mean intelligence, meaning they're both like super educated, and deep dive and didn't stop at the traditional medical thing. And they started looking at all kinds of alternative therapies like hyperbaric oxygen chambers, which then they purchased for their house and they, I mean, stuff that I mean, whenever they come out, I don't know why they even come to see me. I'm just like, so what do you want? What have you read? You're gonna teach me I got several patients like that run like we should probably meet at the coffee shop I learn from you. But..Eric Rieger  What's it like to have to have a kiddo who who has a breakthrough after the training, so maybe you have somebody who's been non verbal, and then suddenly they..Paneez Kahkpour  It's greatest like every, you know, if someone else looking at it may not seem like a very big change. But from someone who doesn't say anything to like, give me a sound is just incredible. It's, you know, it's those little baby steps that make it a, you know, a big change. And so those baby steps are the big ones. Eric Rieger  I'm curious as a parent when they see like this one little victory that helped them kind of buy into the process that Okay, we've got this little victory here. This isn't time wasted, my child's doing better. And maybe they expand their acceptance of things that you're yeaching them to do at home.Paneez Kahkpour  Yeah, I mean, I think so to a degree. Yeah, they, especially the ones who, because I do home health as well. So the ones who see are in the sessions or they can hear they're like a, you know, earshot away, they can hear it. I think it's super helpful. Because, you know, they see like, how much time is spent. And then you get that one little like, like, vowel sound, or like, you know, kid thing more or something super simple that we take for granted, because, you know, we never had any issues with that. But yeah, it gives them hope it gives them you know, like a light at the end of the tunnel.Ken Brown  So, like I always do when I just think what's going on what's going on at a cellular level, how is this happening and you're dealing with the end product of this which is necessary, which communication is the key, so I've never told you this. But anyways, I grew up I was a really bad stutter. And so my ability to communicate was really limited. Like for the first six, the first six grades, and I was put in remedial classes, because they just assumed that I was stupid. And what I did is rather than stutter I did a type of stuttering called blocking. Right? I could see the word coming. And I'm like, I'm gonna stutter on that word. Eric Rieger  Really? Ken Brown  Yeah, no, yeah, it was bad. And so I would block and then I could not get the word out. And then it just became this facial contortion thing. So I'm extremely empathetic to the fact that communication is how you're labeled. So if you cannot articulate yourself, oh, he's so articulait he's must be intelligent. If you cannot verbalize what's going on, then so I'm really well, I went to speech pathology for years and then when I.. So I didn't learn Spanish as a child, I learned Spanish as an adult in med school and went back to the same speech pathologist that I went to when I was a child. And he was just like, crap, you're greedy. He's like you how bad you were. Now you want to like not stutter in another language, because it all kicked back in and then tremendous anxiety and everything. So the ability to actually communicate and a speech pathologist role to help somebody do that, whether it's somebody's post stroke, whether it's somebody that is autistic, whether it's somebody that stutters, is incredible because we're judged by how we actually articulate. And it's the social norm. And I love how you're saying that if I can get somebody to just acknowledge I can see that they're getting it.Eric Rieger  Yeah Ken Brown  That's what's cool. There's something in there. And I want to my my passion is the gut brain access, and I believe that autism is really no different than dementia. It's over activity, it's really no different than stuttering its activity in a certain neural complex, which prevents you from having the appropriate connection. It's all electrical. And there's some really cool stuff. Johns Hopkins is going to do a study on a molecule called sulforaphane coming up, too, because they're showing some deep some improvement with that, if we can find this. And so, the reason why I think it's so interesting that we talked about diet because I've seen in my own practice, autistic their 16 year olds, because that's the earliest I can see him. When we improve their gut health, their brain health improves. So to anybody that's listening that has an autistic child, I think that people like you are making a huge difference. And I think that we have to continue to realize that, that there are people out there working on a cellular level and there are people out there working on the functional level, and that's what you're doing. You're changing the moment. It's great if I say Oh, hang in there. for 10 years, there's a drug or a new study that will come out, but you're grinding it out. That's what I love. Paneez Kahkpour  Thank you. Eric Rieger  That's awesome. Ken Brown  What's your favorite thing in that job?Paneez Kahkpour  No session. No days the same. You're always keeping you on your toes all the time. Keeps it fun, and you get to play with kids. It's great.Eric Rieger  Sounds creepy when a guy says it.Ken Brown  So Eric, Eric actually tried to be a at home speech pathologist. But I mean, for some reason showing up in the windowless van. Eric Rieger  Kind of.. just said candy on the outside. They asked, Why do you want to do this? I just want to hang out kids. That's awesome. Thank you, Paneez so much for coming. Paneez Kahkpour  Thanks for having for having me.Eric Rieger  Absolutely what an incredible show. Ken Brown  You know ...I just love it. I mean, I just admire you so much. You. This is like, like we talked about the whole show. It's a story of endurance. perseverance of being open and vulnerable. Last episode, we talked about being open and what makes people that way. And every characteristic that we talked about you absolutely show the willingness to see new ideas. Try, just get out there. And if you don't succeed, just keep adapting slowly. Paneez Kahkpour  The only way.. Ken Brown  So where are you? I'm gonna put you on the spot again. Where are you at? 10 years from now?Paneez Kahkpour  10 years from now, hopefully still in remission..Hopefully, I mean..Ken Brown  She said that she kind of looked at me like, well I don't know keep me in remission..Paneez Kahkpour  That's on you. Hopefully in remission, you know, hopefully I went to grad school and accomplish that because, you know, working on that right now. Maybe working in a hospital, maybe have my own private practice something, something along those lines.Eric Rieger  Now, I don't know you didn't prompt me because I don't know but I don't know if Paneez is one of the Crohn's patients that we have currently that is taking Atrantil and CBD combo is thatPaneez Kahkpour  I was just on the CBDEric Rieger  Just on the CBD. So I okay, yeah, that's what I wanted to give us your perspective and what you felt. Did you get more control over?Paneez Kahkpour  Yeah, I mean, so the thing is I overall I felt great, but because not going on again. Thank you Remicade. I've been feeling pretty good.Eric Rieger  Sure Paneez Kahkpour  Majority of the time I don't really have too many you know, issues maybe a little tiny players here and there but nothing too big. So overall, yeah, I just feel good. I sleep well. You know, no complaints.Eric Rieger  No, that's that's the awesome part. I get to see the patients when they come through just like you've been through and there's a handful that have just verbalized. I don't worry so much about taking, whether it happens to be Remicade or anything else like that as often They're able to space it out just simply because they feel like they've controlled their inflammatory process. They don't have the flare ups like that anymore. I mean obviously they're adhering to a specific diet for them. But it's it's curious because it CBD to me four years ago I didn't I didn't believe the hype at all. I had to wait till we proved it clinically before I thought there was anything to it.Ken Brown  Well, we this is this is where I want to end up in 10 years I want to end up with the ability to heal people's guts and their intestines so that we decrease neuro inflammation and it all comes down to overactivity your Crohns is because your immune system is overactive. All we got to do is ratchet it back a little bit. And fortunately, Remicade figured out by doing it in one particular manner that worked really well which really well for you. I got a lot of patients it doesn't and I'm not bashing Remicade at all We love all and that's why we tried these different biologics. That's why Reed had an anticlimactic shock and he had to go and humera and his doctors you just sit there and you'll Wow, contrary to what people think we really all want to cure for this. Eric Rieger  Sure. Ken Brown  We really want to care we I could sit here and do if I had my 10 year goal is just Well, this show is huge and we've got you know, we're having fun doing it still in 10 yearsEric Rieger  Yeah Ken Brown  Cuz I like doing it and then I leave the show and I do like 20 Hemorrhoids and then I just go home Eric Rieger  WowKen Brown   I love hemorrhoids Paneez Kahkpour  Sounds like a good line.Eric Rieger  Big goalsKen Brown  Big goals, has nothing to do with you know..Eric Rieger  Someday I'll have a full tank of gasKen Brown  I'm a.. maybe I'll have a new pair of jeans. I don't know. Yeah, no. Eric Rieger  It's a little thing. Ken Brown  It's dude, keep your I mean live the dream just keep the dream real accessible. Paneez Kahkpour  Attainable goals.Ken Brown  Attainable goals.Eric Rieger  Weird way in that episode, but yeah.Ken Brown  Well I want to..Well, we're almost done. I want to ask one another thing here. Just let's do a shout out to your mom because she suffered a lot through all this. Paneez Kahkpour  She really did. I love you, Mom, thank you for everything. Ken Brown  Wave at the camera.Paneez Kahkpour  Thank you. Love you. The best mom ever.Ken Brown  Can you say I love you mom and Farsi?Paneez Kahkpour  ....Mom.Eric Rieger  Big shout out to all the parents of all all kinds of diseases like that. I mean, you are your kids champion.Ken Brown  This is the look at the camera one more time. This is this is the beautiful face of Crohn's disease.Paneez Kahkpour  Think of Crohns and see my face?Ken Brown  Yeah, and this is the beautiful face of a janitor at a..Eric Rieger  Camp Sweeney.Ken Brown   Camp SweeneyEric Rieger  It's been a while but yeah. Well said it.Ken Brown  I think that is a great episode. I think it's very touching. I want to thank Dr. Mike Wiesburg for telling his story. That is very compelling. Go over and Get the book in the end. You can see by the way he writes that and that was like five minutes. Yeah. Like I mean, you know his his novels are incredible. I want to thank you so much Paneez for coming on and sharing I know that it's like really personal and stuff but we just need to get the word out to the Crohn's and colitis foundation camp Oasis thank you so much for everything that you guys do for all of this. And ultimately, I'm hoping that through some polyphenols like Atrantil and CBD, we can start making people feel better heal their guts heal their brain, stop the immune system and we will eventually get to the point where we would talk remember that time when people used to develop Crohns?Eric Rieger  Yeah, that would be a great day to get to in fact, you can help them get to that day by donating to the Crohn's and ulcerative colitis foundation and if you go to gutcheckproject.com check the show notes for this show. We will be certain to have the links to you can check out camp Oasis how to be a volunteer how to give to Crohn's and UC, it's it's, it should be a goal.Ken Brown  If you go to KBMDhealth.com and put in a code Persian princess but has to be in Farsi, you get 120% off. Eric Rieger  Yeah, good luck getting that keyboard Paneez Kahkpour  I have it, i'll go use it right now.Ken Brown  Eric we're losing money!Eric Rieger  It's not gonna work.Ken Brown  Don't do that. Okay, nevermind. I retract the Persian princess code in Farsi.Eric Rieger  Thank y'all very much for tuning in again, check project Paneez. Thank you so much for making time for us today. Paneez Kahkpour  Of course, Thanks for having me. Ken Brown  Awesome. Eric Rieger  See you all later. 

Uninvisible with Lauren Freedman
061: Author & Celebrity Journalist Dibs Baer on Life w/ Rheumatoid Arthritis

Uninvisible with Lauren Freedman

Play Episode Listen Later Feb 12, 2020 61:50


Dibs Baer is a New York Times best-selling author and celebrity journalist. The author/co-author of six books, including, most recently, Lady Tigers in the Concrete Jungle: How Softball and Sisterhood Saved Lives in the South Bronx, she was formerly the executive editor of InTouch Weekly, and has worked on staff at numerous other publications. While she has been published extensively across varied media, she’s best known for her celebrity interviews. Dibs and Lauren connected over a piece Dibs was writing for Creaky Joints, the foremost online publication for arthritis patients (including RA and fibromyalgia patients, among others). It came to light that Dibs lives with rheumatoid arthritis (RA), and has for some time. It also just happens that she is transgender. The intersection of layers of invisibility in Dibs’ life became a conversation, and Lauren couldn’t help but invite her on the show to share more. Uninvisible community, meet Dibs! Tune in as Dibs shares… how her early symptoms manifested that fatigue comes hand-in-hand with chronic pain, and that these symptoms create mental health concerns of their own that her pain was largely in her extremities — hands and feet about the Frankenstein shuffle, as experienced by RA patients typical age of onset for RA that she lived her early years as an out lesbian, and came out as transgender around the same time she was diagnosed with RA that her family was very supportive of her coming out that she experienced body dysmorphia in relation to her gender identity, and had difficulty looking at herself in the mirror…and that this identity confusion was compounded by the onset of RA, which made her even more confused and angry at her body that she has healed mentally with years of therapy that she is still legally known by her female-identifying first name, although she goes by “Dibs” — and that this can become an emotional hardship when being called at doctors’ offices and elsewhere that she had her breasts removed in 2012, and is uncomfortable showing her scars at certain doctors’ appointments because she fears the judgment of others that her treatment includes infusions of methotrexate, a cancer drug — but used in MUCH smaller doses for RA treatment, as well as Remicade (an immune suppressant) that RA is closely related to psoriatic arthritis and ankylosing spondylitis that one of the most common complaints among RA patients is not wanting to take methotrexate infusions — but in many cases, it’s a necessity for quality of life that getting an RA diagnosis made her start taking much better care of herself that she fears smoking may have triggered her RA that there is a high prevalence of RA among first responders from 9/11 — and she lived directly across the river from the Twin Towers and was in NY in 2001 that she now plans each day around flares as they come and go that her treatments can cause gastrointestinal side effects, and that those can be difficult to work around day-to-day how difficult it is to have an invisible disability and maintain a 9-5 job that she has to plan her life around infusion scheduling — a constant 8-week cycle that the US healthcare system doesn’t help all people equally

About IBD
Health Insurance, Accommodations, and IBD at Work

About IBD

Play Episode Listen Later Feb 10, 2020 28:21


People who live with Crohn’s disease or ulcerative colitis have more to consider when it comes to the workplace. The cost of inflammatory bowel disease (IBD) means that a comprehensive insurance plan is a must, which may limit job choices. A flare-up or complication that results in absences can lead to poor performance reviews or difficulties with supervisors or co-workers. How can people with IBD cope? Three women who live with IBD, Megan Starshak, Mary Elizabeth Ulliman, and Tina Aswani Omprakash, tell their stories about missing work, being underinsured, and changing jobs while managing IBD. Information discussed in this episode includes Clostridium difficile (C diff), pouchitis, Crohn’s and Colitis Foundation Help Center, IBD and the Americans With Disabilities Act, The Family and Medical Leave Act, and Financial Help for People with IBD. Select pharmaceutical company assistance programs: Cimzia (certolizumab Entyvio (vedolizumab Humira (adalimumab Inflectra (infliximab biosimilar Remicade (infliximab) Renflexis (Infliximab biosimilar Simponi (goliumumab Stelara (ustekinumab Tysabri (natalizumab Xeljanz (tofacitinib Find Megan Starshak on MeganStarshak.com, Twitter, and Instagram. Find Tina Aswani Omprakash on Own Your Crohn’s, Facebook, Twitter, and Instagram. Find Mary Elizabeth Ulliman on Instagram. Find The Great Bowel Movement on Facebook, Twitter, and Instagram. Find Amber J Tresca at AboutIBD.com, Verywell, Facebook, Twitter, Pinterest, and Instagram. Credits: Sound engineering courtesy Mac Cooney. "IBD Dance Party" ©Cooney Studio.

Gut Check Project
A Surgeons Guide to a Plant Based Diet

Gut Check Project

Play Episode Listen Later Jan 23, 2020 83:06


Remember, I am a real doctor Eric is a real crna. We do do real medicine. But this show is not intended to diagnose or treat. Please, if you have any issues like rectal bleeding, go to our website, kbmdhealth.com. Download the E book, learn about it, but make sure that you talk to your doctor about it.Ken Brown   All right, here we are with the gut check project, Episode 29 a super special episode because we have a guest co host, Eric Rieger was unavailable. And so we had a guest co host today it is Dr. Doug Won, who's here. Welcome to the studio, my friend.Dr. Won  Thank you so much for having me here. Truly an honor.Ken Brown  Well, I think that this is gonna be a really really cool show. You're doing A lot of functional things you're really big into treating the whole person. Your background, I think is really cool. I am gonna warn you though. I hope you're a pretty smart guy because Eric's a smart guy. You got some big shoes to fill in. So why don't we at least find out like if you're, you know, like where you actually came from and everything. Tell us a little bit about yourself?Dr. Won  Sure. I'm from South Korea, immigrated to Irving, Texas when I was 11 years old and went to elementary, middle school and high school in Irving MacArthur High School, go Cardinals. And then after that, I went to Northwestern University. I majored in biology and biomedical engineering, and then went to medical school at utmb in Galveston, and once I was done with the medical school, pursued orthopedic surgery at Washington University in St. Louis, and did spine surgery fellowship in Michigan, and then came right back to Irving, Texas, to treat my friends and family members and my local community and Irving, the city that I love, I went back to it and been there ever since.Ken Brown  Yeah, you're way smarter than Eric. Yeah. Of course right now he's probably arguing I didn't hear anything about Texas Tech. So you know, so in his mind, you didn't go to Texas Tech. You're not nearly as smart. But I guess you did say a few other things Northwestern, double major biology, biomedical engineering and everything. So, yeah, I think that I think the show is going to be really great. What I want to do with this show today, you have you and I have very similar passions. We're really big into the functional medicine side of things. I want to cover some anti aging stuff. I want to talk about how supplements and nutrients can actually augment a lot of these different things that talk about your past. Now. You are one of the most accomplished orthopedic spine surgeons and I can I have to pick your brain before we even jump in. I was actually talking to a very difficult patient of mine and I wanted to throw out a disease and just see if you've ever dealt with any of this. I believe That we have somebody who is smoldering into ankylosing spondylitis. Now this actually happened to one of our co workers, but now I'm treating somebody who's acting a lot like she did. She spent about two years just sort of, you knew something wasn't right. And then pow it just kind of all popped up. Have you had some experience with autoimmune diseases and stuff like that specifically as ankylosing spondylitis?Dr. Won  Yeah, absolutely. In our spine clinic, we used to see a lot of patients with ankylosing spondylitis. And then also patients who didn't quite have the the conditions, but they were HLA 27 positive, and they were brewing the different types of symptoms and conditions. And then we also deal with because I also deal with lifestyle medicine. We've actually seen a lot of different kinds of patients with autoimmune disease. And what we usually tell patients is that your genetics and genes may load the gun, but you actually pulled the trigger through your nutrition and lifestyle.Ken Brown  i like how you say that. Yeah, totally. So one of the things I just want to get this out of the way that you You're a very accomplished orthopedic surgeon. You're currently involved a little bit of a legal situation that you're appealing. What I think is amazing what you have done is because you have to put your surgical practice on hold for a little bit. Yes, you have shifted, and have still taken on the role of being a doctor, helping people and being an educator, you have not slowed down at all, you are the embodiment of resilience of moving through. I'm super, I think that's really, really neat. And why did you decide to kind of shift gears, I mean, you were going from scalpel. And I get that you have to take a little break from that. But a lot of people like you would just say, I'll use this as a break to go tour the world and say hi to things and you went I'm gonna use this as my opportunity to help more people.Dr. Won  Thank you. You know, helping people and making a big impact was my passion. That is a reason why I went into medicine and went into medicine because you know, my father suffered from back and he had four back surgeries, and his life was ruined for about 30 years with severe pain and in life You come up with so many different challenges. Either you can crumble or or decide to just sit back, and then the life continue to punch you, or you can stand back, you know, stand up again, and continue to move on forward. And what got me going was as long as I can make an impact and help all the patients, and my passion was biohacking, which I've been doing, you know, all my life. And what I realized was that in medical school, we really didn't learn how to cure the disease. We learned to manage the disease. And through this experience, I really learned how to better manage and then in many incidences, and cure the patients, and wanted to continue to make an impact and help patients. That's what gets me going and that's what's getting me up every single morning. And no matter what anybody says, as long as I feel good about you know what I'm doing and continue to practice medicine in different way. Through health coaching, and, you know, even approaching and these days, I also teach a lot of doctors in Africa. How to treat chronic disease.Dr. Won  You teach doctors in Africa?Dr. Won  Yes. Ken Brown  Okay. I got a segway out of that for a second. What? Tell me about that? Dr. Won  Yeah, so I came in contact with a physician who was really into preventive medicine. He's a personal doctor to the president of Cameroon. In Africa right now, they're facing so many different chronic disease. In the past, before the Africa became developed, there was no such thing as heart disease, cancer, diabetes, or obesity. But as the countries are becoming wealthier, and countries are becoming more developed, they're now importing American disease such as heart disease, diabetes, cancer, Alzheimer's, and they obviously can't afford to treat the patients with American medicine. So they're looking for ways to treat the patients naturally, and also the citizens most of the people in Africa are still hesitant about Modern medicine. So we got in contact through a mutual friend. And we decided to teach the the physicians there, how to reverse the disease naturally. And then also importantly, to prevent them.Ken Brown  Wow and so are you doing some sort of zoom with them? Do you have a lecture series? How are you doing this? Dr. Won  Yeah. So every Saturday morning, I connect through them through zoom meeting. Thank goodness for technology. I don't have to physically be in Africa. I would love to visit the continent, sometime soon. When things free up, but utilizing the technology, we provide the lectures, mostly to physicians, but also just about anyone who's interested. And we open it up to the whole community. And at one point, we had people from seven different countries connecting seven different countries in Africa.Ken Brown  Oh, wow. That is that is fantastic. So even before you had to kind of take this little hiatus from actually cutting on people and doing spine surgery, you've been thinking about this for a long time. You've been working towards the changing, changing the disease progress, you made a living for many years taking care of the end problem of people having wearing their bodies down, then you as the spine surgeon go in, and you take away their pain and you help them. But even then you were thinking, and what can we do to prevent this?Dr. Won  Yes. Oh, absolutely. So we've been giving free seminars on how to prevent and reverse chronic disease naturally, for about three years. I initially did not necessarily want to give the seminars myself, I'm not a good public speaker. And so I wanted to set up the infrastructure and then invite one of the physicians to do it. And he did it in a couple of times, but it took him away from the family. And it takes a lot of effort to prepare different topics. So I thought this was so important. And as you know, when we're in medical school, maybe we had an hour or two hours of lectures of nutrition, and how to reverse the disease naturally. Well, actually, we didn't learn anything about how to reverse the disease naturally in medical school. We learn how to just manage the disease. And so once I saw the light, I said, I have to share this information with everyone as many people as possible Ken Brown  Even as a gastroenterologist when I trained as a fellow, it is called the division of gastroenterology and nutrition. And I think we got like, half hour a week on nutrition. I know that it's supposed to a split the title. Gastroenterology and nutrition.Dr. Won  Yeah. And look at the hospital. You know, once I had a patient after a very big surgery, and he had a mild, MI you know, mild heart attack. And the next morning when I went up to the patients for patient had eggs, bacon cheese, for breakfast and lunch, I said, this is wrong, and then go to any hospitals, whether it's Dallas or anywhere else, go to the cafeteria, the hospitals are serving disease causing food in the cafeteria and to the patients. I said this is wrong, right. That is the true crime. And I said, you know, it was one of our mission to to really empower the people and teach me How to Prevent and reverse the disease themselves.Ken Brown  We should do a video where you actually come to my hospital to the doctors lounge. They give free food to the doctors and you walk around that doctors lounge. There's bags of m&ms. I've taken pictures of this. There's m&ms there's, this is really funny. There's actually bowls of like gummy bears. And I'll watch and people will just go by just grab a head. Start eating on the way out. I'm like, there's so many things wrong with that. Not just the food, but a lot of hands been in that bowl.Dr. Won  Yeah, actually, I got in trouble with that one of the hospitals here locally in Dallas I actually took a picture of what they were serving at the doctors lounge and then post it on the social media. Oh, and then I got called into the principal's office. The hospital CEO.Ken Brown  Oh, before we get called into the principal's office, since I'm not good at this part. This is what Eric does real well. One thing disclaimer both Dr. Won and myself are real doctors yet this is not intended to treat anybody or give any medical advice if you have that unusual rash or joint pain or anything, this is not here to cure or treat you. But this could help cure whatever it is or not, or at least reverse what's going on by lifestyle changes, not through medical advice. And the other thing that we always need to do is really give love to our sponsors. Our sponsors Atrantil my baby, my little polyphenol complex, which we're going to get into a lot of stuff about this because Dr. Won is a whole food plant based doctor. And those vegetables all have polyphenols similar to what we have, in Atrantil. And we do know that that actually can work like the Mediterranean diet, and do all different kinds of things. And of course, the KBMD health CBD, I'm a big fan of cannabadial, we get into the science of it, we're going to learn more and more. I don't know if you've gotten too much into that. But the one thing that we talk about a lot because I start meeting scientists, like we have discussed before when you have when doctors say there's no science and then you're meeting the bench researchers that are out there. There's gonna be a field like you're an orthopedic spine surgeon you're a subspecialty of a subspecialty. I'm a gastroenterologist I'm a subspecialty of a sub specialty. I guess yours is sub sub sub because you did spine after orthopedic. Your your next level, even though you didn't go to Texas Tech, we're gonna forgive you for that. Dr. Won  Thank you. Ken Brown  Yeah, that's, this is just for Eric because he gets so upset if we don't discuss that. But even when you're sitting there as a sub sub specialist, we've got all these people with knowledge in other fields, that then you start realizing you could be a sub sub specialist. So I've met researchers that I call Endocannabinoidologists because they understand so much on the molecular basis of the endocannabinoid system, which I think eventually we're going to get to, but I think all of it gets corrected if you eat right and live the right lifestyle. So our little disclaimers go to Atrantil.com or go to KBMdhealth.com and take a look at the CBD. So that's usually a Does that a whole lot smoother? That's not really my...Dr. Won  I think you did great. Ken Brown  We have to get that out of there. So, all right, getting back to you, because I this is a rare opportunity to have somebody with both your background, your your skill set. And now this this continual pursuit, this continual change. I'm very similar to you, I've realized at this stage of my life, that moving forward is what keeps me happy. Always trying to see okay, what what can we do? What can we do for the next thing? What can we do for the next level? I try to always talk about a recent news article or something and I want to bring this up. Not to put you on the spot. Dr. Won, How old are you?Dr. Won  I am 48 years old.Ken Brown  You don't look it 48 years old. Awesome. An article just came out out of the National Bureau of Economic Research, which takes on the myth that life begins at age 40. This is kind of interesting, according to this very large study, that they looked at over 257 different countries, different socio economic stages and all that. Fascinating that you're saying that Africa is now getting these Western diseases Dr. Won  Yes. Ken Brown  So it's it's, it's impervious to everybody. The whole world is having the same crisis that I think we face. We just got there a little quicker than everybody else. Dr. Won  Oh, absolutely.Ken Brown  What they looked at is that there is a U shaped curve for happiness. And as it turns out, it bottoms out at age 47.2. And the reason why I bring this up is that there's a lot of people and they were trying to figure out why is it genetics? Is it that the stressors are too much? Is it that disease start setting in right about then you start realizing your own mortality and all these other things. They don't know exactly why, but they were able to account for education, marital status, all these things. And they did show that although it bottoms out by 48 49, people are able to find their way out and they can usually do it through community and through purpose.Dr. Won   Yes.Ken Brown   So both you and I are beyond that now. So now we're in the happiness zone. And I think that you've done exactly that you got through a little curveball and you're like, I'm just gonna keep moving. and I'm going to do this through community and purpose. And what it sounds like, is that the first thing you did is say, I'm going to give free lectures. Tell me about that.Dr. Won  Yeah, so we've been hosting a free seminar, teaching people how to prevent and reverse their chronic disease, and through whole food plant based nutrition. And there's a it's not just in nutrition itself, but it's a whole lifestyle. And that's why we don't like to call it you know, plant based diet is a plant based nutrition and lifestyle. And what I realized was I started going into plant base once I lost a few of my colleagues to cancer, they're physicians, and I myself, always thought, Hey, you know, there's a chance that I might die from cancer and the reason for that is because I've done a tremendous amount of a minimally invasive surgery and use two interpretive X ray machines and, and got significant amount of radiation exposure.Ken Brown  Just explain real quick, minimally invasive and why you would have to be using an X ray machineDr. Won  So a traditional spine surgery, you would make a big incision, right and then open up the spine, take away the, you know, the fat, the fascia and the muscle and then strip all of them off and gain access to the spine. And the whole concept of minimally invasive surgeries, not disrupting the soft tissue, you would make a very small incision, and then utilizing the X ray machine at the time. Now these days, you can use imaging guidance with minimal amount of radiation. But when we were first starting out 15 years ago, it was the typical X ray machine. We were protected with Lead But still, we got a lot of exposure to radiation. So I used to joke around saying I'll probably die of cancer someday. But what I realized was that I don't want to die of cancer Who does? So I started doing just a lot of research how to prevent cancer. And I just, you know, went through about thousand different papers, scientific papers, I realized we all have cancer cells, every single one of us have cancer, so we have cancer. So when we're diagnosed with cancer is a clinically significant cancer that we which we can prevent In many times and reverse, even the study from the MD Anderson state state study showed that number one cause of a cancer was diet. Number two was the tobacco. Number three is obesity, which leads back to the diet, right? And then the genetics makes up the smallest percentage, you know, no more than five to 10%. So we actually have to controlKen Brown  Use your analogy one more time with a gun. I like that.Dr. Won  Yeah, it is the gene or genetic loads the gun, and then the diet and lifestyle pulls the trigger. And so in that we now with better understanding of epigenetics, that the the genes are like the light switches, depending on our nutrition and lifestyle, we actually have the ability to turn them on and turn them off. So So through that approach, I discovered whole food plant based nutrition, which has worked wonders for me, instantaneously, within six weeks, I lost about you know, 25 pounds, and after age 40. They said if you do exactly the same activities level eat same thing. You're going to gain about a pound or 2 every single year, if you know then within 10 years, that's additional 20 pounds. And so starting 40...Ken Brown  I'm sorry to interrupt. I just want to clarify this one thing you chose to go plant based Whole Foods based on the thousands of articles that you researched. Dr. Won  Yes. Ken Brown  So you were not like watching Netflix and stuff. I'm going to I'm going to follow this what the health diet or I'm going to do the game changers This is based you are not influenced you did it all on your own correct?Dr. Won  Yeah. So I actually did it before all those documentaries came out. And the researchers were there. And and what happened was one of my friends from medical school, he came to visit me at one time and then he gave me a book called China Study. And I thought, maybe because he knew that I was also into business. This was about economics book. I didn't even see the cover. And then I kind of put it in the bookshelf and I forgot about it for a long time. And then once I started doing the research, there's a The China Study kept on coming up. And I said, Wait a minute, I think I have a book called China Study. Written by Dr. Campbell from Cornell, and now pulled it out, read it cover to cover, along with other studies, and then realize you can actually reverse the disease. And this has been the studies been going on, you know, there's been studies since 1950s. And so I was convinced I said, You know what, I'm going to do this for myself. And without even trying at first thing I did was wait is, you know, important, but not the most important thing, but I instantaneously lost 25 pounds. And I was back at the weight when I was in high school. And you haven't seen many you know, you don't most people think there's not too many, you know, overweight or obese Asians? Well, in America, there are plenty not and maybe not in Asia, and I was becoming one of them. And so instantaneously, I was back into my high school weight. And then I started exercising on regular basis, and I felt so much better and now I'm I feel better and stronger than when I was in high school. And until about, you know, three years ago, I couldn't even do a single pull up. And and now I can do quite a bit and my goal is by the time I'm 50 I'm going to be able to do muscle up.Ken Brown  Oh, yeah, yeah, for sure. Well, I got to actually Eric super into CrossFit. So he can teach you the whole technique on that. Dr. Won  That'll be great. Ken Brown  We can sit there and do that. It was on last week's show of the week before we actually discussed the fact that when coke really started penetrating China, that's really when their obesity problems started the high fructose corn syrup and all that Dr. Won  Oh, yeah. Yeah, all the the processed food, right. And then, you know, along with the, you know, meat consumption, and as a developed countries are getting wealthier and wealthier they're eating just like American Standard American Diet, right, all the processed food, all the sugar, all the the, you know, high fat animal products. Even in America, average Americans consume about 250 pounds of animal products every single year, which is a tremendous amount, right? And so, and then the China's Study...Ken Brown  How many pounds? Dr. Won  250 pounds. I thought that's a that's a lot right? That's average Americans since I'm I don't eat any somebody is eating 500 pounds of meat every single year right?Ken Brown  I'm gonna look at that cow and go. I'm gonna eat half of you this year. The whole cow.Dr. Won  That is a tremendous amount. I think they said also during the Superbowl, I don't know how they come up with the numbers. Every every year during the Superbowl people consume about 1.6 billion chicken wings. Oh my god.Ken Brown  1.6 billion chicken wings. Yes. For the for the Super Bowl. Dr. Won  Super Bowl. Ken Brown  All right. Yeah, that is a lot of wingless chickens running around.Dr. Won  Yeah, absolutely. And, and you know that the chicken these days doesn't look anything like the chickens from let's say even hundred years ago, because they're genetically modified, you know, and they have so much more antibiotics. They have so much more chemicals, growth hormones, and so people are so concerned about eating food that's not Genetically modified but most people in America don't know where the food comes from. And they don't really think about it especially when it's in a hamburger or chicken sandwich which they really do need to pay attention whether you're plant based or not, you should really know where your food comes from.Ken Brown  You know, I mean I love having you on here because even as gastroenterologist and even though I think like kind of we want to treat the whole body I've I have not spent that much time really going over the whole diet thing because I naively am like okay, this is the weight I want to be. This is kind of what I want to look like when I'm when I'm at the beach is you know, if I start not seeing the the ABS or we go from that six pack to the four pack to the two pack to the no pack. Then I just start working out more. Yeah. And I got a little rude wake up call. Last week I went to I have a functional medicine practitioner. His name's Kevin Wilson. It's smart wellness now. And you know, they they do real Like deep dive into the blood work so it isn't just HDL LDL, it's you know, it's LDL, C it's Apolipoprotein B, it's all this. And my cholesterol went up. I'm feeling better than I ever felt what? And he's like, yeah, you're doing something wrong, buddy. Yeah, and you know, and quite honestly, I'm pretty much paleo so i don't i don't really do dairy or gluten, but I will mowdown some meat. Got to eat my 500 lbs. So you got me rethinking. So he's given me three months to try and reverse this. So I'm starting a little bit slow and so I'm not I'm gonna start watching your videos for sure. Because I did the thing that most people do. I went and watch Game Changers on Netflix and and which is a very fascinating documentary in the sense that that got more traction than what the health and knives over forks and all those other vegan propaganda ones, because I think that they were talking about performance. Dr. Won  Yes, Ken Brown  What you're describing is exactly that you're you this is not an ethical thing. This is not a a conscious choice. You were like, No, I did my research this, I can be healthier.Dr. Won  Yes. I mean, I did this because for my health, and you know, I always tell people that I want to live until 120 years old, I may have had a better chance if I actually started when I was in my 20s.Ken Brown  You know, that will just be you. And Dave Aspy having tea together because he says the exact same thing on his podcast.Dr. Won  I think he says he wants to live forever. And so I don't know if that's possible yet. But they said he, if you do it, right, the kids who are born today have a potential to live until 150 years oldKen Brown  A hundred and 50 years old, have the potential?Dr. Won  Have the potential. But but the sad thing is the kids you know, between age 10 to 12 years old, what percentage of the kids actually have early signs of atherosclerosis? 75% Ken Brown  What? Dr. Won  75% of the kids between age 10 to 12 years old, have already fatty strix. Ken Brown  No! Dr. Won  They all found that the... Ken Brown  That's nuts there's no way! Dr. Won  Even the fetuses are now showing up. unfortunate event because, you know, whatever, you know, may have happened. But when they do an autopsy on fetus, even the fetus, some of the fetus actually have, you know, some fatty Strix, depending on Mother's, you know, a vascular system. Right? So, you're starting at life already having early signs of cardiovascular disease, what is that? Right? And so when mom said, you know, I'm really, you know, sensitive to listen moms who are pregnant, and then also parents, they have such a difficult, you know, challenges, you know, feeding their kids, but they're not really thinking about what they're serving them, right. And I cringe when I go to a breakfast, and then you know, next table, you know, parents are serving their kids bacon, or hotdogs, and the kids and the food that is known by World Health Organization as a group one carcinogen, right. So I think we need to really step back and educate the public and help them see what they're putting on their, on their table. And when I saw the article where the kids, you know, between 10 and 12 years old, 75% of them had already have signs of, you know, cardiovascular disease. I mean, that's terrible. We're not doing something right. And we spend so much money on managing the disease, which we don't do very well. But and, you know, completely forgetting about preventative medicine because there's no money in preventive medicine. Right? That's that was our mission is to actually go to community and and teach them how to eat properly. And so, so we've done not only lectures at our clinic, but also if anybody wants to hear us talk. We'll go and give a talk. And we've gone down to the south side and then the African American churches to church in Richardson at Methodist, you know, pretty much 99% Caucasian, you know, congregation. Or you know, community centers who wants to learn about...Ken Brown  You still have the guts to go to a nice Korean BBQ establishment and give a talk? I like Korean bbq man!Dr. Won  Yeah, you know, for whatever reason Koreans were known for Korean barbecue, but in Korea actually. Their health is declining like in China because the meat consumption has increased processed food, and then their lifestyle is changing. But you know, they used to be one of the healthiest country in the world, because they were too poor to actually eat meat. It wasn't available. Everyone wants to eat. So if you look at all the countries, all the cities and along the Blue Zones, the the cities that have the most amount of centenarians, most people are poor. So by being rich, yeah, you may have money to spend it, but you're actually ruining your health. Ken Brown  Alright. So I was going to ask you this, and it's a perfect it's a perfect segue right now. So I was talking to one of my patients today that she's going to be a guest here shortly what happens to have Crohn's disease and gives back to the community just like you she works as a counselor and does all this and she happens to be a speech therapist for underprivileged kids with autism. So part of this, you know, they, they send them with the with the school system. And so her and I started talking, I started talking about how last week we did a whole show on a chemical that makes plastic flexible, called DEHP you've been exposed to it a ton as a doctor. So have I that's what IV bags are. That's what the tubing is, all the catheters and tools that we use to be flexible so that we're not puncturing where we don't want to use this chemical dehp. And when you said in utero, they're finding stuff as it turns out in utero, if a if a woman is exposed to it, it just goes to the fetus and causes all kinds of stuff. Dr. Won  Oh, wow. Ken Brown  So what her and I talked about is I'm like man, well, what can what can you do to circumvent this autism at you know, I mean, basically epidemic She's like they're too poor to eat healthy. Dr. Won  Yeah. Ken Brown  So now you just said that when countries were poor, they ate healthier. So let's talk about the cost of, of living your lifestyle. Is it possible if I don't have a high income to eat a plant based whole food diet?Dr. Won  Absolutely. When people are thinking Whole Foods plant based, I think a lot of people get that confused and they think it's vegan. And then and they get meat replacement products, which are actually quite expensive. Right?Dr. Won  So when you do... Ken Brown  This guy did that when he watched game changers and it didn't work out well. Dr. Won  Yeah. Ken Brown  Because I think the either the fillers or the soy or something may be very inflamed. Dr. Won  Yeah. Ken Brown  So I backed off.Dr. Won  So one of the things I really you know, it's also talked to the vegan community is that you know, they've already given up the meat which is the one of the most difficult thing for a lot of people. However, they also need to get away from the processed food because most of the the meat replacement products are processed. So when you're eating a whole food plant based, you are eating non processed or minimally processed food. And so the best place you know, and the best pharmacy is actually with F, you know, FARMACY right Farmacy is in the produce section, that is the medicine, that's where people need to go shop. And so if you get dried beans, it costs pennies, right? Versus, you know, getting ground beef or getting chicken breast. So actually eating whole food plant based can be very, very inexpensive. That's why and along the the Blue Zones, the you know, like nicoya, Costa Rica, Okinawa, Japan, you know, Sardinia, and aquaria. All those countries, all those communities, people were relatively poor, they're not wealthy at all, even especially like nicoya they were eating mostly beans Ken Brown  Where's the Nicoya? Dr. Won  Costa Rica. Ken Brown  Okay. Dr. Won  Yeah. And it's one of the cities and Blue Zones that has the most amount of centenarians, right? And and there were most they're all 98% eating plants because they were too poor to eat meat. And they're living beyond and then they didn't necessarily go to the gym, you know, or CrossFit or 24 Hour Fitness, because they walked every day everywhere, they didn't have cars, right? So they're moving their body every single day. They're eating mostly plant, and because that's all they had available to them. And then they had sense of community and, and they had sense of purpose. And you mentioned purpose earlier, I think that is so critical. You have to have a reason for living, right? You have to have why, as long as you have why, and sense of purpose, no matter what challenges are in front of you, you can overcome them. And that's how powerful human beings are. And if you decide to just give up, that is a failure. And no matter how many mistakes you make, how many, you know, failures and debt that you face, as long as you stand back up, and then continue to, you know, pursue your purpose and your why I think Most people will be very, very happy.Ken Brown  Yeah, I think that you saying that you came at 11 years old, you started your journey, probably not the easiest time in your life.Dr. Won  Not at all, I didn't know how to speak English. And but all our family, you know, including my parents, we worked as a janitors, you know, don't want to get my parents in trouble. But when we're 12,13,14 years old, we used to go help our parents, you know, clean the toilets in the building and then I still pass by one of the buildings we used to clean when I was 14 years old. And and that's what we did as a family. And then they, you know, open to the flea market store. My mother was shot at, you know, twice when she was working at the flea market store when she was being robbed. Right. And luckily, they missed, thank goodness and then where my parents lived after I left for college. There was a drive by shooting at my parents house. They got the wrong House, it was supposed to be the next door. But my parents were asleep. And then fortunately, their windows were shattered. And so, you know, we grew up very humble. And a lot of people think that, you know, you're a doctor, you must have come from a doctor family. That wasn't the case at all. And we live in the government assisted housing. But, you know, our parents always gave us you know, good foundation, and always, you know, taught us to have purpose in life. And that really, you know, sunk in with us for you know, since we were little child Yeah, and, and in always the life force, you know, living the life with purpose, and, and that was our mission.Ken Brown  So, you come over here you go through this kind of hardship. Now, we kind of tongue in cheek, talked about how I hope you're as smart as Eric obviously Eric's a very smart guy. He's my crna and he's he could he's still continues to do whatever he wants to do he has entrepreneurial spirit very, very like minded like us. He's very big into purpose into raising his kids the right way and all that stuff. But your your academic background is super impressive. I mean, you know, just for the average person that says, Oh, that's a doctor. Now there's levels of doctor, there's levels of med schools, you gotta really work to get into some of these places. And I, I'm just so impressed that you basically have to put your career that you were worked so hard to do, and you went awesome. I'm gonna work on this now. I love that. I think that is the coolest thing. And I'm learning for you. So I want to ask you a couple quick questions. Dr. Won  Yes.Ken Brown  Because these are the arguments that I get. So the community that I'm in I'm in fact, I should. We'll we'll talk afterwards, but I've been part of some really cool entrepreneurial groups, where it's just like minded people that all they do is sit around and say don't step on this land mine. I blew off my left, you know, theoretically, in a business sense, I blew up my left foot doing that I wouldn't do that, try this software instead try this thing and you know, you read books and stuff like that. Well, a lot of these people are the Paleo community, and they're really smart people, Chris kresser, Rob Wolf, you know, become friends with them in these groups. And what what I'm hearing is, is that in Kevin Wilson, my doctor is not plant based. He's very big into paleo and all these other things. So a couple curveballs towards you. Dr. Won  Sure. Ken Brown  All right. Let's talk about the thing that I get asked a whole lot. Lectins. So you said Dr. Beans do this, what's your thought on lectins? Do they create and then that's going to lead us into the microbiome and and eventually into your entrepreneurial spirit where you continue to grow? So that's where I want to head with this. But can we talk about lectins real quick?Dr. Won  Yeah, absolutely. I think that's a you know, very interesting topic. And so if you think about the Lectin especially in the beans, no one can eat them being raw. You don't eat dry beans, you can eat it, you can't digest it, and we don't recommend it. Right? Because if you eat it, you're going to get nauseated, you're probably gonna throw up. However, if you cook them properly, right, all the lectins are gone, right? And so lectins are there so that the plants can protect itself and so a little bit it's actually healthy for you because you're stressing your body. However once you cook them... Ken Brown  Hormesis.Dr. Won  Yes, absolutely right.Ken Brown  The term Hormesis means that you stress your body a little bit so it adapts.Dr. Won  YesKen Brown  That's why we exercise that's why we fast that's why we do things.Dr. Won  That's why you know, we get exposed to heat that's why we take cold showers right? Ken Brown  I don't take cold showers. I refuse to go that route. I'll sit in a sauna but I will not do a cold shower.Dr. Won  You should try it you know maybe 10 seconds first and you know 15 seconds in the beginning you hate it. But you'll learn to love it. But the lectins...Dr. Won  We're gonna get to elections really quick. Just Just this reminds me my late father in law passed away a few years ago, we were watching a show on navy seals. And a Navy SEAL actually did a obstacle course, where he first soaked himself in warm water, and then did the course. And then they put him in ice water. And then within a sofigel probe, they show that he dropped his core temperature and then through various Navy SEAL techniques, he raised his core temperature. And so my father in law, this is on Christmas, this is about 10 years ago, goes you know, it's Dallas, it's not that cold, but it's cold enough. It's It was like 30 or 40 or something. He goes, I bet you can't even get in that pool. I went out there with my son and my father in law and I jumped in and like a total weenie jumped out in about 10 seconds. So the whole cold thing I think that's funny, but all right, that's the whole point is is that lectins can do this. Let's get back to lectinsDr. Won  Yeah, so but once you actually properly cooked the meals, yeah, I recommend soaking them at least for eight hours or even 24 hours.Ken Brown  Soaking the beans first?Dr. Won  Yes, soak the beans minimum of eight hours. If you have a pressure cooker you don't need to soak them you just dump it in there and you cook itKen Brown  Do can beans qualify?Dr. Won  The can beans are already cooked so you don't even need to cook it you can just open it and start eating them.Ken Brown  Do you find can beings unhealthy or do you always do whole food? Dr. Won  At the house we have both dry beans and canned beans because to make it a little bit more convenient, right. And the can beans are, the studies have shown that they still retain just as much nutrients. And so when I'm really busy, I would open up a can can beans with the my whole grains and mix them up along with different kinds of spices and then along with different greens, but once you cook the bean most of the lectins are gone. So there's really nothing to worry about. And so you don't need to take Lectin you know, supplements or anything like that. If you properly cook the food, then there's really no issues with lectin and if you think about it, so beans are the most known for lectins right? Every single one of the cities, right? There's one common theme among Blue Zones, five cities that has the most amount of centenarians, right? The research by Dan Buettner from National Geographics every single one of them that the common theme was Beans, beans, beans, beans Ken Brown  Shut up! Really? Dr. Won  Every single one of them there was their main source of protein was their beans.Ken Brown  Dang. And I've actually been avoiding them because I'm trying to you know, I've just kind of go with the no grain thing.Dr. Won  Yeah, so the beans is one of the healthiest thing one can consume. Not only it's a great source of protein, but also it's also has so many fodder nutrients. And I consider them as a superfood really, really cheap. Super food, Ken Brown  What are your favorite beans? Dr. Won  All of them, but we have at the house about 10 different kinds of beans. And then when I make grains I usually mix like black beans, pinto beans, white beans, navy beans, kidney beans, along with let's say buckwheat brown rice, wild black rice, barley, mix them up, and then that's how I make the rice and so rice and beans. I don't you know we definitely avoid any refined grains such as white rice,Ken Brown  Oh you do? Dr. Won  Yeah, I we avoid any kind of white anything that's white right?Ken Brown  Okay, so I hope that helped my wife is listening my wife's Puerto Rican. Dr. Won  Uh huh. Ken Brown  So i mean...beans and rice. Yeah, it's just pretty much it's whatever. I'm like, Honey, what are we having? She's like salmon, and beans and rice.Dr. Won  Yeah. That's good. And you just got to put in some greens.Ken Brown  But but but but you avoid the white rice Dr. Won  White rice. Yeah. So the...Ken Brown  As a Korean you still avoid white rice because we love I mean, that's actually our favorite. If we're going to globalize our cuisine for my family, I got a 15 year old a 13 year old and we essentially eat Japanese in this order. Japanese, Thai, Vietnamese, Chinese almost anytime we get a chance to eat out.Dr. Won  You're inner asian. Ken Brown  I'm we are definitely Yeah, it's a it is it is definitely our favorite cuisine. So we end up eating a lot of rice. Dr. Won  Yeah. So interesting fact is that the, the in Asia, you know, while back the white rice was you know, it's extra process right? So this was actually for aristocrats or the wealthy individuals, all the poor people ate brown rice, which is less processed it's unprocessed. Right? And so the the poor people actually live longer they were healthier than rich people, right? Same thing happened 100 years ago, the rich people ate white bread, right? And then the the poor people ate the whole grain bread. And guess what it was a poor people who are healthier, right? So you know, grains, especially white grains, they're extra processed. And so and also raises your blood sugar level much, much faster and raise you know, increases more insulin production or release of insulin. So we try to avoid anything that's processed. So including the the grains. So if you eat you know, brown rice or you know buckwheat barley, black white rice those are the grains that I would recommend that I say it's whole grains not grains, whole grains, Dr. Won  Whole grains?Dr. Won  whole grain.Ken Brown  Beans, beans, okay lectins get destroyed when they get soaked and then followed by cooking and or canned. Dr. Won  Yes. Ken Brown  And then...Dr. Won  Because canned beans are cooked. Ken Brown  Can can beans are cooked and as far as the grains, so yeah, the This works really well for you. And I know right now that there's, you know what I've seen with diets, especially when people make a living like if they have a book or so I mean, I hung out with Rob wolf, the guy looks amazing. He's been keto for 10 years. And Chris kresser is essentially you know, straight up paleo and, you know, I know his blood work is amazing. We've talked about that. And so there are, you know, the the things that actually work it's not working for me. My doctor just told me that's why I'm like, Oh, yeah, we need to we need to call Doug, I need to I need I need to eat his brain and figure out what's going on here because maybe my genetics, so you use the term epigenetics a little while ago. Explain what epigenetics actually is, because there's some confusion around this.Dr. Won  Yeah. So just to simply put it way I like to explain it is our gene is like a light switch. Right? So we are born with certain genes, unfortunately, for some people, and they may have a greater risk of developing certain type of disease. But just because you carry the gene does not actually mean you're actually going to develop those disease. But there's a lot of external factors, environmental factors, including the cancers, right. And so by a proper nutrition and lifestyle, you actually have the ability to turn the genes on or turn them off. So what that tells us is that you actually have a full control. So you know, like Elizabeth Blackburn who won a Nobel prize from UT Southwestern for discovering telomeres did a study with the Ken Brown  She's the one that discovered telomere races?Dr. Won  Yeah. So along with the telomeres, and that's what she, she won the Nobel Prize,Ken Brown  Did not know that wow, out of here, out of here in DallasDr. Won  Yeah at UT Southwestern. Ken Brown  That's, that's impressive.Dr. Won  So she did the research with Dean Ornish, and they got group of patients who had early stage prostate cancer. And then when they did the genetic study, all the over 500 cancer genes were actually turned on. And then they spent three months changing their diet and lifestyle. And then they did the the genetic study again, all the genes were actually cancer genes were turned off over 550 cancer genes, Uncle genes are turned off. So you only took them three months o so especially prostate cancer, right? Especially if you catch them early stage, you really want to treat them with diet and lifestyle change. They said the the traditional surgery, whether it's a chemo or the surgery does not prolong only one out of 49 people actually live longer after getting traditional, conventional medical treatment.Ken Brown  Well, when you start looking at some of this, I listened to a podcast called medical reversals. It was on Freakonomics, the Freakonomics podcast. And they they actually had some doctors on there. And they and if you look back at all these medical reversals, so basically your doctor says, do this, and then we go, Oh, no, that was wrong, because now we've looked at our cohorts of 10,000 patients over 10 years. We can go on and on about that the estrogen replacement therapy, one of the things that's been brought up and I brought this up to my doctor because my cholesterol is statins and statins have not been shown to improve lifespan. And so the question is, do they actually decrease the incidence of events, but it has not been shown to improve lifespan. So now I start. I'm at that stage in my career in medicine where I'm starting to question so many things. I'm having patients come to me, and well, let's throw this one out with autoimmune disease. And you and I were talking about this I treat a lot of Crohn's disease, ulcerative colitis. I use drugs like Remicade and humera. Have you had any experience with as an orthopedist you're going to be exposed to rheumatoid arthritis, you're going to be exposed to ankylosing spondylitis. Poly arthropathy from these other things. Have you had any wins with using your method?Dr. Won  Absolutely. So some of them are my patients and some of them are attendees to our free seminars. And I gave an example of Denise she gave us a permission to talk about her. And so she came to us suffering from severe rheumatoid arthritis and she's been on multiple medications, even methylstrexate as in the past and humira. And humira costs 25 to $50,000 a year. Right? And one of the side effects is heart failure. And she began to have a severe heart issue. So they had to take her off. And and she she was in severe pain. And so I said, you know, you got nothing to lose. You tried everything else. So why don't you try a whole food plant based nutrition, and that's what she did. She did that. January 1, 2018. Within two months, she was in remission. All the pains were goneKen Brown  On her alright rheumatoid arthritis? Dr. Won  Rheumatoid arthritis. Ken Brown  So rheumatoid arthritis is an autoimmune disease. Autoimmune means you something turns a genetic switch on and your body starts attacking yourself. In gastroenterology, I see it with all sort of colitis, Crohn's disease, celiac disease, autoimmune hepatitis. In your field. You see it with the joints.Dr. Won  With the joints rheumatoid arthritis, but we also I've seen patients with multiple sclerosis, right? And actually, this was another patient who walked in or not walked in, came into the clinic on a wheelchair and had multiple sclerosis. So we actually... Ken Brown  In a wheelchair?Dr. Won  In a wheelchair.Ken Brown  That's very advanced MSDr. Won  It's pretty advanced. And and the patient went whole food plant based, and was six to eight months later, when they came back for a follow up visit. He actually walked out walked in with a cane. So he still had weakness, but it got him off the wheelchair and now he's able to strong enough to actually walk with a cane. Ken Brown  Just diet change? Dr. Won  Just a diet change. And he was off to all the medications and he's not the only one and there's a one lifestyle medicine physician even up in New Jersey, a good friend. She was initially infectious disease doctor and during her residency or fellowship, she woke up one day completely paralyzed. Ken Brown  What? Dr. Won  And that's how she discovered she had multiple sclerosis. And to a point she was walking with a cane and she was bad to get on a wheelchair. And she made the she discovered she read an article about blueberries, right? She said No way. There's no way and this can't be and she starts researching and really realized the autoimmune disease starts from the gut. And she needed to find a way to decrease inflammation. And she needed to once she healed her gut, and she changed her complete, you know, nutrition when whole food plant based. 10 years later, she ran a marathon.Ken Brown  I'm sorry, I don't have any Kleenex. Do you have any Kleenex because I have tears of joy. I just had an orthopedic surgeon say that. Everything starts in the gut. Oh,Dr. Won  Yeah. We think that you know, a lot of the the lifestyle medicine physicians and believe that autoimmune disease may be in a different sort of autoimmune disease, whether it's rheumatoid arthritis, Hashimoto thyroiditis, multiple sclerosis, maybe it disease, it all starts from the gut. And then it manifests to a different disease based on our genetic makeup. And so our treatment method whether it's, you know, lupus, multiple sclerosis, you know, Hashimoto thyroiditis, it's all pretty similar. You know, they may, we may make little bit of a different protocol for them, but overall as a whole food plant based, and many of them improve significantly.Ken Brown  Wow, that is. So we've actually, that's actually a common theme that we talked about, we have brought some people in, but my thing is we've got lots of data to show that when you have an inflammation in your gut, that leads to an inflammatory cascade that can cause this epigenetic phenomenon. And so somebody sitting around listening, so I want to talk about what else you have going on, which means that you've taken it to the next level, but I everything about, about this show and about what we want to do is talk science first. Clearly, you're a brilliant And you know, you're, I'm a, I'm a gut doctor. So you know your s-h-i-t. So I wanted to throw this article out at you because it's fascinating that we can talk disease. And I could sit there and say if you've got rheumatoid arthritis if you got ms if you have anything, but there's also one underlying thing that happens to all of us and you keep talking about the Blue Zones. A recent review article, my little secret weapon will eventually be able to disclose who it is, but she sent me an article yesterday. And with you coming on it is a review article on the new insights for cellular and molecular mechanism of aging and aging related diseases. herbal medicine is a potential therapeutic approach. So in other words, what this title says is, yo we're all aging. And why do you want to load the gun faster than it should be loaded? So what this article looked at is they go into the background A little bit where 900 million people in the world are over the age of 60. Dr. Won  Wow. Ken Brown  And you just pointed out that it doesn't matter where you live now it looks like it's it's pretty much spreading everywhere. So aging, which can be divided into both pathologic and physiologic. So if you are perfectly healthy, you're going to physiologically age if you choose to load your gun faster, that's pathologic aging. And this article gets into really cool geeky science about the complex biological processes and the decline of tissue and origins and structural degeneration and then they go into telomeres and then they go into the fat, a common thing keeps popping up. And it is reactive oxygen species or oxidative stress. Dr. Won  Yes. Ken Brown  So stress at a cellular level, or inflammation at a subtle level leads to aging. Dr. Won  Yes. Ken Brown  So if you didn't care about anything about the fetus having a heart attack or a 10 year old having coronary artery disease, We spend a lot of money trying to look younger. I just got done talking about the other article that said that at age 47, maybe that's when men look in the mirror and go, Oh, I'm I'm there. I don't know. It all comes down to reactive oxygen species. This leads to they can actually get into the actual mechanism. So one of the things I run into that we have discussed, which is I'm sure you've run into because I think your field is a little bit less holistic than gi, which is probably because the gut affects so many things. But I imagine if you're trying to talk to one of your colleagues at a conference and say hey, plant based they probably look at you like what?Dr. Won  Yeah, I'm I don't represent typical look of orthopedic surgeon right? So if you imagine orthopedic surgeon those of you who don't know like in medical school, we are like the cords pedic surgeon smart jocks, right? Everyone's hitting the gym, you know, bone broke me fix. Big guys, ex-thletes, right? And then somehow I snuck in as a nerd, right?Ken Brown  So I have I have a friend who played football for the San Francisco 49 years played at the University of Notre Dame. And we have or he's very good friends with orthopedic surgeon named Brian rhadigan. And he played linebacker for Notre Dame, and if there is ever the avatar of what I thought this guy was just jacked, and you know, and he's an orthopedic surgeon now for Notre Dame. Dr. Won  Wow. Ken Brown  But anyways, yeah, so yeah, you you are talking different than the typical orthopedic surgeon.Dr. Won  Yeah. And so but yeah, but I think even with orthopedics, and also especially in spine, some of our patients, after if they choose to follow our diet and lifestyle modification, they came back even with herniated disc, most of the inflammation was gone, pain was gone, and so they they would cancel the surgery. I said Congratulations, right. And so if I can help patients, that surgery is definitely the last resort.Ken Brown  Say that one more time you got paid to operate and you were happy when you didn't have to operate?Dr. Won  Yeah, absolutely. Because there's plenty of patients who's not following the lifestyle modification and who is in agony, who failed all the conservative treatment, who's going to need the surgery. But you know, what I would love to be able to do is to prove to the medical community that so many of the surgeries and procedures that we do are completely unnecessary, because if people are willing to make the lifestyle modification, if the physicians actually know and teach their patients, how to make the modification, because most of them do not know. Right, then I think, you know, many people can avoid significant surgical procedures, whether it's a cardiac cath open, you know, open heart surgeries, which we know that does not extend anybody's life, right. And same thing with spine surgery. And, you know, orthopedics is a little bit If you break a bone, you broke a bone and you need surgery to fix it right?  Ken Brown  Don't try to hobble into whole foods after that skiing accident.Dr. Won  I don't think that whole foods is  going to fix that broken bone, but it may help you heal faster, but you're probably going to still need surgery. And so that is one of my mission and I get a great enjoyment out of it. And you know, I remember one patient who walked in who had a thoracic herniated disc. And you know, in order to do the surgery, we have to do a thoracotomy. So basically cracking our chest open the compress the lung in order to get to the spine from the front. And I said, you really don't want to have this surgery. We can do it if you want to. However, why don't you give me three months make this changes come back in three months. If it doesn't work, then we'll go ahead and do the surgery. She came back to clinic and three months along with her husband, she lost 40 pounds. He lost 60 pounds, right? And she said her pain was gone. And she said doctor, I don't need your service. anymore awesome congratulations. So I think it is very possible and you know once once you have seen that I just get a kick out of itKen Brown  I'm feeling like a little jerk right now because we did a show on using cell phones while there people around the bathroom doing social media posts and I I told everybody to keep doing that because it creates hemorrhoids so they can come see me. I feel like a jerk. I'm over there encouraging, sit on the toilet longer and make an appointment with me.Dr. Won  That's funny.Ken Brown  Oh, you're making me look bad man. I want to talk about something about this article because I we use the term reactive oxygen species all the time. Now one of the things that they got deep into this article is about a lot of the end origin disease that kills most of us. cardiac disease strokes. dementia. A lot of it comes down to blood vessels. Yes, the endotheliam meaning that as our blood vessels, all this inflammation leads to endothelial dysfunction, and impaired activity and arterial stiffness. And the reason why I bring this up is because I'll plug this the polyphenols and Atrantil we do know that they actually improve the most polyphenols when taken in. There's literature for this. But when we first launched Atrantil we did it strictly for people that bloated and then we had all these people that kept staying on it. And that's when I started backing up because I was looking at one little problem then went, Oh, this is actually it's sad that it's that I'm now learning because all I've been doing is doing plant based, but I started with a pill and now I'm working my way to lifestyle. Yeah, which you're doing lifestyle. And you realized, Hey, I can help people in different ways. So you noticed immediately that endothelium is really important. And when we talked before and you brought me some gifts, I would like to talk about what else you have going on here because very clearly, you have put some serious thought into this. And then I came backwards. I started with a plant based product to treat something and now I'm learning about a plant based lifestyle. Yeah, you did the opposite. You started plant based lifestyle and said, I'm going to produce the best product for that. Yeah. So tell me what you got here.Dr. Won  Yeah, so one of the things that we developed was, is called Neo Nox is a nitric oxide booster,Ken Brown  Neo NoxDr. Won  neo neo, no x, no x, and this product was developed without intention of developing a supplement company. what we realized was as I was doing research, even as a physician, we knew that heart disease was a number one killer, but I didn't realize how severe it was. It is actually the number one killer of both men and women worldwide. Right? And, you know,Ken Brown  Yeah we start seeing once women go into menopause. Yeah, they get the same risk as men.Dr. Won  Yeah, exactly. And, and so and a lot of women just getting neglected and they think it's a man's disease. And but women develop a cardiovascular disease just as much as the guys and, and one in three deaths in us is related to vascular disease. So pretty significant amount. And it all comes down to endotheliam and nitric oxide, what I realized was the most important molecule in our body because it saves endotheliam, and is produced it within our endotheliam. However, as we age, by the time you're 40, you lose about 50% of your ability to produce it. By the time you're 60 you lose about 85% of your ability to produce nitric oxideKen Brown  Say that one more time.Dr. Won  So by the time you're 40, you lose about 50% of your ability to produce nitric oxide, which is the most important molecule in our body.Ken Brown  Why do why do we do that? Dr. Won  So a few things number one is produced in your endotheliam. Right intercellular is basically the inner lining of your artery. And so, as we age, we develop atherosclerosis, we damage the endotheliam. So therefore, we lose the ability to produce the, the nitric oxide, but along with that... Ken Brown  So the inflammatory process damaging the endotheliam does not allow us to produce the one molecule to repair the endotheliam.Dr. Won  Exactly. And so and not only the nitric oxide, is that the strongest vasodilator that lowers of blood pressure, and then also vasodilate the vessels so they're more nutrients and oxygen can be delivered to the end organs, right. It also stimulates the stem cells and activates the stem cells and mobilizes the stem cells, Ken Brown  nitric oxide does? Dr. Won  Nitric oxide, and that's how we really actually got into the nitric oxide because we knew we needed to boost the nitric oxide to our patient when we're doing orthopedic stem cell therapy, right to to help them prevent either You know rotator cuff tendonitis and tear surgeries Ken Brown  We had we had weighed with 10 on our show the orthopedist. Dr. Won  Yeah. Ken Brown  From Fort Worth that had the the Panama stem cell clinic.Dr. Won  Yes. Yeah. Ken Brown  We deep dived into stem cells. That's some cool stuff. Yeah.Dr. Won  And but, but most people are looking for that magic pill. They want the injections, right? And the stem cell therapy, but you need to activate them and people who needed the most are typically 60 Plus, right, sometimes 40 Plus, but most of the patients we have arthritis are 60 Plus, but they can't really activate their stem cells because they don't have any nitric oxide. That's part of the reason why people develop cardiovascular disease. people develop diabetes, right? people develop erectile dysfunction, which is a vascular disease. Right. And so that's, that's why the even Biograph Cialis only works on 50% of the population.Ken Brown  So one of the reasons why game changers has been so much more well received is that they have a whole segment on nighttime boners Yeah. And how eating a plant based diet actually improves erectile dysfunction. Dr. Won  Yes. Ken Brown  And so and not just erectile dysfunction actually improves nocturnal erections I should say. Yeah, boner seems a little bit unprofessional. Dr. Won  You are a doctor.Ken Brown  But um, yeah. So that's, that's one of the things so it's, it's when you talk anti aging or you talk sexual performance, that's what people spend all their money. Yes. They don't sit there and go, Oh, I'm going to have a heart attack. Yeah, when really, it's all the same process. It's all the same thing. The thing that's making you look older, the thing that's making you not perform as well in bed is the exact same that's going to kill you! Dr. Won  Exactly. And, and, you know, the dementia, which are mostly now we're realizing that is a vascular disease also, because you're just not getting enough blood to your brain, right. And so, and also lack of energy, you know, after age 40, everyone's fatigue suffering from fatigue, lack of energy, because  mitochondrial biogenesis is actually initiated by nitric oxide also. So it helps nitric oxide stimulates the production of mitochondria, which is the energy source. Ken Brown  There we go. Yeah, so that's the that's the energy source of every cell. Every cell has a little power plant. Yes, it's called the mito

Crohn's Fitness Food
Renee Taylor balances western and holistic medicine in her Crohn's journey (E48)

Crohn's Fitness Food

Play Episode Listen Later Jan 6, 2020 52:58


Describing her Instagram as “a young gal’s adventures with Crohn’s Disease & other chronic illnesses,” Renee Taylor continues her IBD advocacy on today’s podcast where she shares her Crohn’s journey and how she’s seeking to find the balance between western and holistic medicine. Diagnosed with Crohn’s Disease while a junior in college, Renee shares her many ups and downs over the past two years. Renee was diagnosed with Autoimmune Hepatitis as a child, so she’s no stranger to battling chronic illness. But, since being diagnosed with IBD, she’s faced some of her biggest challenges yet, including flare-ups and erythema nodosum episodes that are so severe that she can’t walk. Renee talks about her medication history, from her first few (and only) days on prednisone to finding immediate relief with Remicade. But relief was short lived as she failed out after a few months and then switched to Humira. Once again, however, she started to reject Humira and it was then, around July 2019, that she decided to get serious about her lifestyle and began focusing on changing her diet and reducing her stress levels to help manage Crohn’s. While fitness has always been a part of Renee’s life, she stresses the importance of re-evaluating what fitness looks like after being diagnosed with IBD. As she describes in the interview, sometimes fitness must be put on hold during intense flares. She talks about how she’s learned to celebrate the small daily victories and reminds herself that the flares are temporary. Overall, she feels better when she gives her body the chance to sweat and move and fitness gives a much-needed routine and structure to life with a chronic illness. During flares, she tries to hold on to a sense of normalcy, even if it’s just reading a book or connecting with a friend. She’s learned to adapt her diet to include foods she tolerates and avoid common inflammatory foods like corn, soy, and gluten. Renee has also found the power of investing in her interests and not being afraid to follow her passions, one of which is advocating for IBD patients. Through her advocacy, she has found a sense of normalcy and connection to those fighting the same battles. This month, she’s starting a collaboration with Avery Rosenbloom from @talktummytome on Instagram called “What the F Wednesdays.” They’ll be diving into the abyss that is early adulthood in a series of Instagram live videos. The first episode just launched yesterday, January 5th, on her Instagram (@killinitwithcrohns) and future episodes will be recorded every Wednesday evening. Follow Renee on Instagram: @killinitwithcrohnshttps://www.instagram.com/killinitwithcrohns/ -------------------- Cellercise Rebounder: https://www.crohnsfitnessfood.com/cellercise Pineapple Clothing Leggings: https://www.crohnsfitnessfood.com/pineapple(20% OFF with code: STEGIS)

Gut Check Project
Jeremy Kinder, CBDTakeout, Curated & Trusted CBD

Gut Check Project

Play Episode Listen Later Nov 7, 2019 73:08


Welcome to the new location of the gut check project. I'm your host, Eric Rieger along with your other host, Dr. Kenneth Brown. How you doing Ken what's going on?So well, we've moved from the Spoony studio and we are attempting our first own podcast over here at the new studio at the KBMD Health studio. We are and guesswhat, you know we are still on the Spoony network, but I can't express how nice it is for you to now have a studio that's closer to the clinic. It's closer to where we do the procedures. It's the same distance for me no matter what.And most importantly, it's closer for our guests like Jeremy who just flew in from Austin. All the way from Austin because we got so much closer. Yeah, thank you guys. Much closer. Awesome. So our firstguest here in the new studio is going to be Jeremy Kinder here with CBD Takeout and I'm going to let Jeremy kind of take it away a little bit about what is special about CBD Takeout here in just a moment. Dr. Brown real quick, do we have any catch up items that we needed to do to kind of put in front of Jeremy to see if he wants to weigh in on anything?Well, we got like several visual on so first of all, we want to hear the story about how you and Jeremy met Sure. We want to talk about how much synergy there is. Whenever you start meeting people and you start connecting with people. We came back from the baby bath water event and just met incredible people. We had Tim powers over here who we're going to have back on because we actually had the equipment. We were unpacking the equipment when our first real guest showed up and he was kind of helping us just show how to...like we were like wiring this stuff together. Check thisout. Before Tim came over here, he was over at a hotel and then put his iPhone down to simply turn around and pay a guy at the bar. No, no, no, he was going to turn around and refill his ice tea. Oh fill his iced tea.Like five feet away at like a Homewood suites are just like some. Yeah, you know, like normal family.A little hotel. Did somebody grab his phone?  Withinlike three seconds, three seconds took off. So he was in town. And so me my wife, my daughter, my son was out of town, me, my wife and my daughter, we're going to take him out to dinner. And I pick him up. And this is what we have to do is figure out so now we're, I'm learning how to move the camera. So now we're back on me. Yeah, nice. Sweet. So we're working on that. And I picked him up in like a boss. I mean, like a boss. He was like, Hey, man, what's up? I'm like, why did I have to face you know Facebook you?  Yeah, funny thing and he stops in the car, funny thing my phone just got stolen I'm like when? He's like, I don't know eight minutes ago. I'm like, you are a boss. I stopped the car. I'm like do we go to BestBuy? Do we get you a flip phone? What do we do here? This is crazy. So was he calling youfrom like an iPador something? He sent me and I'm not a Facebooker and so he sent me a message said hey, phones, phones not working. It was cool about it phones not working. message me through this and I'll I'll do it through my iPad. When I picked him up, I mean, he was just like, I would have been curled up in a corner, crying, whatever. And he's like, yeah, let's just go to dinner. It's all good.Let's go get a drink.Let's just I mean, he was just cool and super, super neat about it. And then that evolved into a realization for himself and go ahead and expand on that. The coolest thing was is he found how addicted he was to his smartphone.Yeah, he said he began to sleep better, he communicated better with people that are in front of him. His anxiety level, he said, the first day was palpable, where he didn't feel captivated by the phone constantly vibrating for something for him new to look at.So, man, I don't know how much y'all want me to talk because I bet I'm a talker I'll throw in stuff on everything. But my wife and I have been talking about how do we decouple from our devices and I've tried everything if you're getting a second device or getting an Apple Watch and you know, all kinds of different stuff and honestly, the thing that that's helping me the most is just discipline you know, but I'm not going to you know get on my device and it's freaking hard I mean it's really like a you know like a drug fix of it My mind is telling me Hey, I need to check my phone go through the cycle of okay check Instagram, check the email check, you know. And then 15 minutes later I've been on my phone the whole time and I I literally don't need to be on there. But that's probably about a year ago we started talking about how how we can improve our lives and have better sleep quality and a lot of that stuff and decoupling from electronics was a big part of thatI don't remember was that Aaron File at baby bathwater who made the statement that there's a boxthere's a box..No it was Jack Olocka. Oh Jack Olocka. So it was Jack Olocka . So Jack Olocka...I'm  a little bit echoed here. Is that you know what, whatever we're just we're just gonna run the first one is studio thinking first one new studio figured out. So Jack Olocka . So Jack, so this group that we're with is like, it's like, you know, like when you like meet a bunch of people and you just go oh my gosh, I'm I'm like around a bunch of like minded people yeah well Jack Olocka is a PhD in psychedelics, all his research has been in this and like not like, Oh, I'm really good at psychedelics like he actually has a doctorate on the neuro plasticity and what happens I mean, just brilliant guy. And he gave a little speech there's this thing called a Baby Einstein, we're just going let it echo doesn't matter now. Where the Baby Einstein where everybody kind of gives either an ask or a give. And you know, his give was there's something called a kitchen safe. And what you do is you put your phone in the safe in the kitchen. Yeah. And when you set the timer, you nothing can get that phone out until the timer stops. Like there's like like even if somebody breaks it, it's just pretty much like yeah, you better have a landline going Yeah, yes. You know. And so unless you have dynamite and a crowbar and the reason is is because people are so addicted to their phones and we know that the blue light affects sleep. If you look at the how important sleep is and how affected it is just getting in just shutting your phone off and not looking at it is probably the most important thing that you can do.Yeah, yeah. My problem though, is you know, I come from the technology world and my house is wired like I have sono speakers everywhere and I have lights that are on smart plugs and all that stuff. And I did all this before I knew the the harmful effects of emf and so now I kinda thinking. So if I put my phone in a safe like I can't turn my lights on or I can't listen to music. Or turn the air conditioner down. I'm hosed. Just honey. I can't flush the toilet. Right. My phone's in the safe.Yeah, yeah. So you know we're talking about how to it maybe shut all that down and all that butyeah. That's funny. So let's talk a little bit about CBD take out that's why you You came up here today we're going to explore opportunities that are synergistic between the two of us. I was going to kick it off by saying one of the things that allowed you and I to get on this wavelength to start talking. So I went down to Austin to join a friend of mine. Marie and I are really good friends with the Leath's. Rennon Leath is basically the founder of a podcast called Lazy Sundayz Lazy Sunday, Lazy Sundayz and that's with a Z. So lazy Sunday's podcast. It's really kind of cool. It's four people who got together and have anxiety issues. So they forced themselves to start a podcast to confront their anxiety and now they just recorded their 50th Show and The 51st comes out this weekend. Yeah, so They wanted me to come down and help him see it. They held it at the Tequila 512 headquarters. Thanks to Scott Willis. Oh, can you do me a small favorover there and hold up that bottle. oh yeah that's the old vintage bottle.  this is so now I'm going to change the camera here so this is the vintage bottle. This is the original bottle of tequila 512 that when a they were in a tasting contest according to your buddy there that he said that they call this a shit-tastic label. They did. Shit-tastic.Once they replaced it with the new and they said yeah old label kind of cool pretty shit-tastic . Yeah,the tequilas phenomenal . The label is bad. So can you guys hear that?Yeah.I don't know. Maybe it? Is it? Is it too loud on me? It's been first podcast.It might just be the headphones popping?I don't know. It's probably something that we did with the microphone.Ron. So run. Shout out to Ron and Paul, everybody else that helps us out with this that they're going to be dying laughs I'm going to try and puttogether Episode 21 good content from Jeremy bad audio from me.So, anyway, we go down to do the podcast we did it at Tequila 512 casita there in Austin and man great turnout. Yeah, they had what...60 people? I was running down to the liquor store trying to buy more liquor. Yeah, everybody was having a great time. Theymaxed out the what 512 made available to them. Yeah. And then we had to shut the party down at nine. That was the rules of that particular neighborhood. So, great podcast, great turnout. And then Jeremy, I'd heard Jeremy's ads on the podcast previously, I've listened to my friends podcast before and I was really intrigued because your first and second interview specifically talked about what y'all do at CBD takeout is essentially you're going to find CBD on CBD takeouts website. It's been vetted. You've made certain that the certificates of authenticity are real, and that the measurements of everything that's in there, it's real CBD per the label that's given to you now. It was at baby bathwater that we learned that just on the retail side 26 to 28 offerings of CBD to 1 are fraudulent for every good one was 26 to 28, which are not so thankfully for someone like Jeremy and CBD take out. This is a bastion of where you know, everything that you're going to find on there is vetted. And I think that hopefully over time, you'll find the KBMD will be  a part of their repertoire.I think that would be awesome. And so I mean, Jeremy just get everybody up to speed you come from a long lineage of CBD growers. You're the seventh generation of a hemp grower you have extensive experience with CBD, your great great great great grandfather was the first original CBD producer. And now you decided to go digital but am I a little off on that?No that's spot on? I guess you read my bio. Yeah, like that couldn't be further from the truth.No. So my, my career's been is in technology, so I've worked for a lot of software companies and sold, you know, really high end platforms to major corporations and may have had a great time doing it, But I wanted to do I wanted to do something different that I was passionate about. And so at the same time that I was building technology companies and doing all that I just have always had a passion for health and fitness. And I think that that goes back to being a collegiate collegiate athlete. So I was a cheerleader at the University of Kentucky. Oh, yeah. went there on a full ride. That's fantastic. died doing that. Yeah. My wife's also a cheerleader. She was a cheerleader at the University of Texas. So, you know, we grew up as gymnast and so athleticism is in my background. But then about, I don't know, age 21-22 I started and that's really kind of when things peaked I started having gut issues. And back then I didn't mean that was, what 25 years ago, something like that i there wasn't research that was readily available, you couldn't go to the, to the grocery store and find gluten free products, none of that it was really really difficult. You know, I went to doctors and had lots of blood work done and they always came back with your you're healthy, you know, but I didn't feel something just didn't feel right. And so that kind of started me off on this whole exploration of, of diet and trying to find balance in my body. And you know, I've been tweaking that for 25 years and that that's what really led us to starting CBD takeout and and getting into this industry.Were you ever normal or more did you actually feel that there was an event that took place that changed everything?Yeah. So when I said that, you know, around 21 22 is kind of when all of that peaked when I started peeling that onion and going back, so I had spinal meningitis when I was six months old. So massive amounts of antibiotics, you know, had IV's in my head, all that good stuff. And, you know, at that point, nobody really knew about balancing flora, and that, that antibiotics could basically just kill all the good bacteria in your gut. And so I think from, you know, six months old that I was at a disadvantage. And then by the time maybe 15 or so, you know, just like, you know, normal teenager started having acne, and I got on tetracycline, so I took an antibiotic every single day for, you know, maybe two years. And I remember around that 15-16 I remember my body changing not in the teenage way. Just I remember Remember things with, you know, with going to the bathroom and stuff like that, that there were changes, but I didn't know. I didn't know why. So I started having a lot of athlete's foot and a lot of rashes and stuff like that. But so it was there an event? Yeah, I think there was probably a lot of events along the way that then you couple that with a college life style of shoot we were we were sponsored by Papa John's, at the University of Kentucky. I mean, we could call up and get a large pepperoni pie for like four bucks. We were We were rocking that every other day.I have this image of Jeremy and his buddy catching that one cheerleader that they throw up in the air and she keeps getting heavier as the season goes on. It's like yeah, we gotta find a new sponsor.Yeah, yeah. What thank God we had ephedrine back then.That's great. So Jeremy, when when you realize that there was an opportunity there to basically take...Well, no, actually you went to this where you are starting to realize some changes. So what progressed? And how did it take to take you to where you are now?So back that up to the question? So how did my dietary issues affect? So yeah, I think that that that just spawned a passion within me and starting to research that there were ways to put my body in a position that it could heal itself versus looking to a quick fix of let me take a pill let me you know, kind of that that approach tothis was during college when you were starting to think about this, or when did you start to do this? Yeah, yeah, that's, that's about right. It's really interesting, because everybody that we've met, that we've met in this field, when they start doing that they really get drawn to medicine. Yeah, and you didn't. Well, I, I mean, career wise.Oh, gotcha. Yeah. So I think What I really contemplated back then getting into more of dietetics and and going about it from the diet route, but man I am not a scientist by nature I think and and even at that stage that the issues that I was having, that you have concentration issues so, so to follow a, you know, a profession and medicine, It just wasn't in the cards for me So, and plus I like to talk so it kind of led me into more of the sales avenue of business.You know, Eric puts people to sleep for a living and he talks the whole time so you can still do medicine. yeah, you can do it, but they don't ever respond to anything I say. So yeah, pretty much.Yeah. He has full on conversations with all my patients and they wake up happy like subconsciously they love communicating with Eric.Yeah, it's always a good dream. Yeah.So obviously then you still pursued, your career, you said that you got into software sales correct? And but you didn't lose the passion for trying to find something that was going to allow you to heal. And I like that you say it that way, find something to heal and not a quick fix. Oftentimes the companies that cater to the medicine world now, it's pharmaceutical, and it's always a quick fix. It's a patch. You know, I didn't know that growing up. I always felt like well, you may be dependent upon medicine that's just the answer. And what I've learned is that's oftentimes absolutely incorrect. You can learn to heal from the inside and get so much better. So what turned you to that for your own personal health?So the point around pharmaceutical companies and that methodology if you look at foundationally how how they are built, they're not financially, they're not, they're not compensated to heal you, to fix you, they are compensated to get you on a regimen, that you come back and be a repeat customer. If anybody knows about publicly traded companies, the the end goal is to increase the stock price. So pharmaceutical companies, they they don't have and this isn't a political statement, this isn't a perspective of whether they're bad or good. It's simply foundationally they have to satisfy that stock price and if they get people off of their drugs, then that stock price does not go up, it goes down, right? So, from from that perspective, they they are not going to be in the business of healing people.clear my throat there. It's alright. Sofrom the perspective of,of healing yourself, I come from the perspective that of that we're creative beings and then We, God created us in a way that we should function properly. But what stands between us and that is desires. So does the food tastes this way? Do you want? Are you chasing the way that that tastes? Or do you not want to exercise because you're too tired? So there's the I think that there are things that stand between us living an optimal life, that it comes down to choice. So I begin to peel that onion for myself in my own life of what was standing between me and optimal health. And over time, you know, I have experimented with different supplementation or different diets and so on and so forth.So that my perspective. I want to expand a little bit about what you just said, because that's never really been addressed before, which is that our health is related to our desires. Now we know that fast food industry we know that processed food industry, they hire, I have patients who are chemical engineers, their sole job, and they've told me this is to figure out how to make the food more palatable, more satiable, more like everything about it that you want more. How do you put a coating on a freedom? So it goes down easier. Yeah. So we have the pharmaceutical industry over here trying to combat high cholesterol, obesity, coronary vascular disease. We've got the food industry over here trying to figure out how to how do I get you to eat more Doritos? How do I get you to eat more Fritos? And I love how you said that because what you basically said is something I've never thought about. We battle our desires, but our desires are influenced by both the media scientist there's some really smart people trying to get us to take certain things.Certainlylet's go back to the beginning of this conversation was about technology. So I was in the technology business, and the exact same thing that you're talking about of how they create foods so that they're more palatable, they look better, whatever they do the same thing with, with technology. So your, your phone is created in a way that they call it gamification. How, how do they attract you? And it's really like a drug, how did they attract you in a way to keep you using the device? And once again, I'm not saying something bad about the company companies are here to be to be profitable and build a company. It's up to us to choose if if we're going to engage that or not. So it goes back to your desire. Are you do you have fomo right? So do you have to look at your device and start figuring out what am I missing? What am I missing? And I need information or you know what be at peace that you're world and things going on in your life is what's important to you versus everything else.We're getting super deep, real quick, but I asked just another No, no, I love it. But I want to ask a couple quick things because Eric and I talked about our family and our kids all the time. You have kids, family, wife married Tell me about that real quick. I've been married for 17 years.Two kids, 14 and 8. Two girls. They're fantastic. Beautiful.Yeah. So the reason I bring this up is because a lot of times since I've had kids, so I have a 14 year old a 12 year old about ready to be 15 and 13. Eric has his sons. And when we sit there and you live your life, when you start thinking how do I want my kids to live? It really changes your perspective. For sure You suddenly just go Oh, no, I want and the fomo thing like you don't realize that you're on your phone, but when you see your kids on the phone, you go Wait a minute, and they look at you and go, but you're on yours. That that puts you in check. I mean, Eric and I talked about this all the time.Yeah, it's difficult. I remember the when Ken and I actually just started working together. Whenever my oldest got a an iPod, they would communicate with other iPods. And I remember saying, Man, this is kind of weird. I don't know if I like it or not, but he does every now and then need a ride because he's going to soccer and basketball back then. And it helps. Maybe it was the lure that conveniently lure at that moment sank its little teeth in and then about three years later, he's got a phone and then suddenly we're like, well, that's certainly certainly is convenient in the younger we didn't have to wait till he was the same age. He actually got one about nine months later and honestly, looking back at it, I wish we had just never jumped off of that cliff. I do think that we both Marie I both have looked back and tried to carve out the time that we just absolutely don't have a phone at dinner when we're  having family conversations etc. But the thing that stinks, is it when it's on you and you're not planning the formal talk with with whomever you whomever you're talking with even if it's your family sometimes you like oh yeah, yeah, two seconds let me finish real quick. That never existed growing up and in all I feel is more fatigue at the end of the day just because of that.It's kind of weird. So wesomebody shared with me this YouTube video that you should probably share with your daughters. It is a Harvard psychologist which is talking about the affects and I've shared it with Eric before but it's essentially thatthethe fact that we have these desires and things when we get a like or and I say we because we're all human or get a like when we get a share when we get whatever it releases dopamine. Yeah. And dopamine makes you feel good for a quick second.They knew that when they created it. Isn't that nuts?  For sure that's nuts! It's the gamification.See that molecule right there? That's dopamine, advancement of dopamine because we sit there and look at this, and I just think, wow, I want to actually...when we talk about it, we don't want. We don't want dopamine pleasure, you want happiness, Serotonin is the happiness molecule. And when you release dopamine, you actually reduce your happiness molecule, which is serotonin. So everything that is done, and unfortunately stopped, sorry. Everything that is done is to get people to do more of it. We're talking about tequila companies we're talking about. And the beauty is this is a great segway for us to talk about this, that this isn't a discussion of desires or everything. It's a discussion of how do we start healing? Yeah, well, one way to start healing is is that because of all this crap that's going on, we as a society, have an Endocannabinoid deficiency. And I think that's kind of what you were gonna get at that you were you went from the space of digital to realizing I need to start helping people.Yeah. Well, I got to this place in my life whereI had enough money to where I could just say, you know what, I'm not going to do this anymore. And I mean, we could go down that route of, should I have done that in the beginning anyway, I don't know. But I decided I'm going to apply everything that I've know that I've learned to this point, and apply it to something that I'm passionate about and giving back to people. So all of this research that I've done, and you talk about not going down the route of, of medicine. I did it in my own way. Right. It was, it was experimental. And, and so I gained a lot of knowledge along the way of what worked for me and I wanted to I wanted to give back so we took that that knowledge especially in the technology space and applied it to I mean if you go to our site it's I'm going to brag a little bit our site is is fantastic. We've got a....what's the URL real quickCbdtakeout.com so we've got a bot on there that readily answers questions now it's about to get an upgrade so he's not perfect right now but we're we're growing and we're we're making updates to the system but technologically we're we're, we're spot on. So we wanted to build a fantastic site that was really easy to use. And then we saw an issue in the market with this flood of CBD products that were unregulated and because I have toyed with supplementation for so long, I there's so...You can say so much and it's hard to weed through all of that junk and so we wanted to help people by vetting those products and having a marketplace of fantastic products in one place that like you talked about that have the the lab tests and every product has the lab tests that you can pull up and see on our site.That's awesome. I think it's I love it when people have a success in one industry and then want to give back. That's essentially what you're saying.Well, I wanted to do that all along, but it...No we don't want to tell our audience that I made you take off all your gold chains and your watches and what you've got like for Lambos out front right? Right. Not that well. I can just pay my bills. Let's say it that way. But it is it's just fascinated because you come from a background of health and there's no doubt about it, dude. I mean, Kentucky cheerleading. I have had friends that have been cheerleaders and they're like the most. I mean, they're like now CrossFit beasts that I work out with. I'm just like, holy cow. Yeah, these guys like that is hardcore. Yeah, Kentucky cheerleaders a dynasty. I think they're on their 23rd national title, I lose count. But my my teammates still a coach their Jamal Thompson. And they are, they are beasts. They're fantastic.It's so I mean, essentially you're a an elite athlete, gets sick, tries to discover his route develops a successful business. And then wants to give back and you're giving back by CBD takeout by trying to make sure that people have access to proper material, proper products, proper supplements. I think that's fantastic.Yeah, I think the other thing to say there is, we were dedicated to the process. You know, when there's a product that everyone wants and needs, it's very easy to get on the latest gimmick and we refused to do that. We We're taking our time to vet these products to vet these companies and, and really vet the trends. And that's that's not easy to do that takes a lot of time to figure out what is right for for people and what products are right for people. So that's important to us.I was just looking at something because I don't hardly ever get to correct anybody but I want to have some fun since you went to Kentucky. Kentucky did win a ton of national championships in a row. And they finally were unseated by the Texas Tech Red Raiders this last year. I just had to throw that out there. So welcome to the show.WhichI love the I rarely get to correct anybody just asked Marie. Yeah, I'm going to use this opportunity even though we're on our first podcast and I'm going to insult our first guest, but I never get to do it. I never getto do it and do it becauseHave you seen Scott yet?Since we were... Oh no I haven't. Okay well the nevermind. I'm holding that okay. Yeah okay. But back to Texas Tech now look them up and see how many they have won. I think it's one.You're right. We just did it we just did it so you can come on the show.In fact, you know, they are always...I work for the organization that you know for that competition. Varsity spirit worked for them for a long time. They want someone else to win because nobody wants to go compete because like well, Kentucky's already won and the competition hasn't started yet. So there are they're actively hoping that someone comes and beats the team.I went I went to the football game this last weekend because gage went out to go visit Tech's campus and when we were there, they talked about how there was finally a school to unseat Kentucky. Yeah, I'll still give mad props. I mean, that's, that's a huge thing. I mean, so it's basketball and cheerleading. Everybody knows that about Kentucky. It's becausethe university really supports the program. If you go to other universities, they just don't support the program and I understand cheerleading is a huge liability and it doesn't make any money. Kentucky just really appreciates. I mean that there's there's been a guy there. T. Lynn Williamson he is the university attorney. And he started the cheerleading team at the University of Kentucky. Dedicated.How dedicated Kentucky is to finding talent, too. He doesn't come from Kentucky. He's originally from Denver city, Texas. Yeah. Yeah. I'm from Texas.Yeah. How'd you end up going to Kentucky? Doing cheerleading? Yeah, yeah.So I went to a junior college first. And I got recruited. So the junior college I went to was really good at cheerleading as well. And you come from a background of gymnastics is that correct?  yes. Yep. Man that's impressive.Well, now I'm just old and...You're not that old.So one of the things I want to ask you did you have to quit gymnastics after you grew the mustache because the aerodynamics threw you off, or is that something that you can still do gymnastics with? Actually when you twist it makes this cool whisp.you spin faster.So one of the secrets if you guys are not out there the reason why Kentucky wins and gymnastics every year is that all the men have to have mustaches because it actually it actually augments the twists and turns. Yeah, yeah, that is awesome. So you have this really kind of cool background and then you do CBD Takeout and you're doing it for one reason. It's one reason is to source proper supplements. Is it only CBD or do you guys have other supplements or what are you doing? So it's all CBD in different shapes and forms, right? We've got salve, we've got capsules, we've got tinctures, we've got massage oils, there's quite a few different we stay away from the gimmicks like CBD candles, CBD toilet paper, that kind of stuff. We don't carry that. We want good value for our customers, you know, if you if you can't absorb it into your system, and there's really no value to it, we don't carry it. But, you know, honestly, I've built a business for scale to be able to help as many people as we can to reach as many people as we can. So in terms of direction of will we can carry other products, I'm open to that. Does it help people? Does it increase the benefit of CBD? If there's a product out there, maybe cue  Atrantil. That that works together that has a harmonizing effect, we would consider that.When he and his wife went home, he let me know that she'd already picked up Atrantil from people's pharmacy. Oh, that's awesome.Yeah. Well, what I love about this is that you're not doing the death by 1000 cuts. You're staying true to one thing. We're going to do one thing. We're going to build a really good website first. Yep. We're going to make sure that the thing that I'm good at which is digital, we're going to do it well. And then we're going to offer this. Now you have a calling to this, why do you think it's going to make a difference?I think in that goes back to you talking about building it in a way that we can execute properly. I, I'm convinced that and I mean  there's science behind this, you can talk about this that our bodies need cannabis. And and so I, I think that there's some interesting reasons why people have been have been kept from cannabis for so long. And I'm frankly I'm just excited to be a part of call it a revolution Call it whatever. I think the impact that cannabis can have on people lives because you can remove so many pharmaceuticals, you can aid with cannabis. And then that puts you on a road. I don't think cannabis is the end all. I think that it can still be a crutch depending on how you use it. I think it is. It has the potential to put people on the road to healing. So I think it's very powerful. I think that there is a fantastic opportunity. If we can wade through all of the noise and trust me people there is a lot of noise in the business right now. The the people that I talked to day in and day out. There's some great people that are getting into the cannabis business, but there's a lot of people that honestly it's the the old culture of just drug dealers that have moved one step over to legitimising and they still have the same principles and so  we're really committed to the culture of cannabis and representing it in in a proper way and we could spend probably an hour talking about what I think the the proper way to do that but... Let me just clarify really quick for the listeners here so cannabis what you're talking about right now on your website is purely CBD correc?t Correct. Yes and we split that up. We have some that are guaranteed THC free we've got a filter on that. If you need something that is guaranteed THC free you can find it easily. But everything is hemp derived so it's all . 3% or less so all federally legal.And it's so frustrating because when we get into this we understand that the confusion about it. Cannabis where you're knowledgeable about it because we know that comes from the same genus species of the plant, but everybody hears cannabis and they have a connotation of it.Yeah but in and that's the that's the thing that I'm talking about changing because I believe in the power of THC as well in proper dosing. But here's the thing is we don't even in legal states, the the science has not come along enough for people to get accurate. dosing, time and time again, it's still trial and error. And so while you can't overdose from THC, you know, from a medicinal standpoint where you know, you can't kill yourself, but it can cause psychological issues if you consume too much THC. So that's the culture that I'm talking about where THC has this, this negative connotation because it's been attached to this attitude of rebellion. How high can I get, can I get the strongest THC product available, and I just think that's wrong. And because it's been represented that way, then we don't get the the truly beneficial aspects of THC and and so many people have dismissed it, but then they'll go get, you know, an anti anxiety drug that causes 15 other issues. So how do we move back to this culture of, you know, business people should be able to consume small amounts of THC that are blended with other cannabinoids. So if it's just THC, that's where that's where you have issues with. I'm super paranoid and I'm freaked out. If you were to consume a nice dose of CBD in conjunction with that, it balances it out real nicely. So I just think that the industry is in the elementary stages right now and I'm talking to all of the the entire cannabis industry. I think it's in the elementary stages. And we're excited to be a part of that.You know, we if anybody's interested in getting a little bit more into this Chris Cresser just had a little client in both friends of ours just had a little client who is CEO of oh hi energetics on his show. And Will went into deep detail about the history of hemp, CBD, marijuana, Cannabis, whatever. And it's been ingrained in our culture for so many years, our genetics actually eat a certain amount of it. And one of the things that's really fascinating to me is that we used to feed our livestock, hemp. And when they would eat that, like a chicken would have an anecdote of 250 milligrams of CBDA in it and then our bodies would convert it. That would be the acidic version of it to get all sciency and stuff. But basically, we were getting CBD in our diet until the US government decided to say. Okay, now wait, this is an illegal product, we're going to ban it and then the farm bill came around just recently in the last five years and started changing things and now it's become more available, but I think you're exactly right. I think that the black and white notion of I'm going to get high or I'm not going to get high I'm going to do this and that am I  doing something? No I was testing mine. But we're...Eric you could probably attest to this remember that the Joe Rogan does a whole set about how people have done that they get the little gummy. Eric and I, Eric and I are huge comedy fans. Yeah, yeah, like like he actually takes his sons to comedy shows when they buy and don't like to see what you see. Who the guys you've seeing live?In the last year we've seen Bill Burr, Tom Segura, Marie went with us on that and we also saw Hannibal Burris. Yeah. I mean it's it's a pretty rich and actually gauge for his birthday last week he and his friends went to go see Eric Andre that's off the chain. Wild stuff right there.Yeah, Who was the comedian at  baby bathwater that just wrecked it.Oh, goodness. What is her name? She killed it.   She's a total amateur and just gets up there and just starts. She was inShe was in between bands on the top of a mountain and when I mean she nailed it. It was like, you gotta have your own Netflix special nailed, really. And she just sat there with her iPhone. She's like, I just don't talk about this and just killed. Love it. I respect comedy at that level, just having the balls to get up there and just do it is nuts. No kidding. So anyways, I'm digressing, but basically Joe Rogan does a whole set about how the guy gives him a gummy and he goes, just eat the arm. He'slike the arm? What kind of shit are we making these days? They just are gummy bears.They just they are. I can't tell you how many times I hear that story of people. They're like, oh, I'm going on vacation. My wife and I are going on vacation to Colorado. And we're going to eat some gummies so they eat gummies and they're like, man, I got so high. I was freaked out and like what I mean, that's what I'm talking about. You don't have access to how do you dose properly and edibles are especially bad because you're going through your digestive system and how much did you eat before that? How hydrated you are? So you know the insulin uptake yet all of that... Jeremy, have you ever tried alcohol? Drink this bottle.Right? Right just chug it. Yeah.yeah. Can you guys hear me crackling? Yeah, I don't know. What's up with that?Yeah, I think so. You know what I'm gonna go take a little pee break real quick. Okay, figure we forgot the crackling you guys keep talking and you're on camera right now. All right. Okay so what we'll do is we'll hit here real quick about whenever someone does visit CBD takeout something that's interesting to me. We get feedback a lot about people that take CBD currently and order it from KBMD health. Most of our feedback though, is directed towards people who come to see Ken for gut issues in particular, IBD such as Crohn's, ulcerative colitis, advancing proctitus, even to a lesser extent, a lot of folks who have found issues with celiac disease, but that began to open up a completely different arm of people who have systemic autoimmune disease. So a lot of IBD's are viewed as are viewed as an autoimmune disease in and of themselves, but so is psoriatic arthritis or all the way up to Alzheimer's. Where do you get a lot of your reviews from? Because the thing I really love about your right, your website's great, and I've seen it before, but as I'm watching it scroll now. You get so many athletes on here. Yeah. And Brandon, the host of lazy Sunday'z podcast, has his own CrossFit gym. So the synergy there and your application obviously the way that you're marketing to these folks, where do you get mostl of your reviews and do you see them kind of branch out a little bit?Yeah. So one of the things that we looked at when we we developed a site was what are the the markets that we want to to support and athletes is definitely one of those you can see that pretty quickly when you go to the site. And the reason that we wanted to focus on athletes is because the CBD's ability to help with recovery is is really, really great. So and what I mean by that is I don't think it's any secret that CBD helps with sleep, sleep quality. So if you can improve your your sleep quality, then your body is going to recover better and more quickly and for athletes that that's key, especially within the CrossFit, CrossFit world. It's how much how much output can you get out of your body, and so recovery is the biggest is a big deal there. And then the other thing is, you've got receptors in your skin, Endocannabinoid receptors and so you can use topicals to reduce soreness. So athletes use our products very consistently. So obviously a group that we we wanted to service. Another group is the aging community that does have issues with specifically arthritis, because, like you mentioned, Eric arthritis is a symptom of, of inflammation. And so CBD has shown that it has the ability to lower inflammation. And so we get a lot of feedback from that group. I think also that group is, I don't know, I feel like they are more open to providing us feedback. We get more more feedback from that age group than we do from our athletes. Athletes are always talking about it when we see them, but that aging community man they give us a lot of reviews and feedback, a lot of emails and we hear fantastic stories, you know, you want to talk about reaping the benefits of creating a company. We talked about this quite a bit of, you know, customer saying, I haven't been able to walk in, you know, six months because of my arthritis. And now I it's changed. This was a word that was used, it changed my countenance I had to go look it up. But it really is helping with that arthritic community. In fact, we've written a couple of blogs on on how it helps with arthritis.Wasn't Chad Hudson, his father, one of those that..He was, yeah, he got off of opioids. I mean that that stuff blows me away when we look at the opioid crisis that that we're having in the United States. If if we are directly directly related to helping people get off of opioids, man, I'll keep doing this forever.That's that's, that's no joke. So Ken, just while you stepped out. I was talking about how we get feedback through KBMD mostly it originates around gut health gut issues, gut inflammation about what we've started to basically branch out and get reviews from people going, I have autoimmune disease, etc, etc. But essentially, like Jeremy just outlined, it all is based around inflammation. So according to their website, if you look at everything and it's it's based around athletes and recovery is where they started getting their reviews, but now, just like what we experienced the KBMD health, you're starting to get reviews from all different facets and it's the geriatric community is pretty impressed I think with their, their access now to CBD. And it's unfortunate that it took until their golden years to start finding something that is going to work for them.There's a couple of, if I can, a couple of other areas unless you're going to if you're going to change the topic. We gotta goat in here. We've got a goat. Goodness gracious.So a couple of other areas that we are focused on on the site. One is, is pets because they also have an endocannabinoid system. And, you know, we hear dogs freaking out on the 4th of July.I'm sorry, I was trying to time that to open for you. I was going to have a bark and I tried to download an animal sound and it became a goat. So but one of the things that people don't realize is that goats take CBD too. Yes, if you have goats. Let's make sure that...We have a goat section...look for the goat tab.So one of the things so I I've actually talked to a lot of high goat athletes that have been going to your site CBD takeout Yeah, yeah. These are elite goat athletes. These are goat jumpers goat runners, and they love it.Yeah, yeah. We're thinking about rebranding it to just be I mean the feedback we get from the goat community.Of the animal species they're some of the best credits in there. Yeah. And they can they can actually afford high level CBD.You'll find that selection in your takeout C Billy DeeI was trying to think of something, something snappy, but that was good.I'm really good. I'm really good at URLs, man. Yeah.So yeah, so um, unfortunately, I have to, you know, one of the one of the addictions that Eric does have is that he buys basically he owns every domain name.He spends hours on Godaddy.I got an ideaAll of a sudden you'll be like oh, that'll be funny to have like goat CBD athletes but somebody bought that?I have JeremyKinder.com if you want it?Yeah.Just kidding.20 grand.I'm sorry. No, I mean, the same endocannabinoid system so it it helps with anxiety and you know, dogs freaking out on the Fourth of July and if they have arthritis, I mean it's really beneficial. So we've got dog treats and tinctures and all that stuff for cats and dogs and animals.So let's just really quick because when we talked on the phone, we were talking more like my whole role is science. So not to sit there and a joke about goats and goat athletes and all sort of stuff but let's be honest about something. We we have a system called the endocannabinoid system, just as important as the cardiovascular system, neurologic system or gastro intestinal system, which I'm a specialist in. Eventually we're going to have doctors labeled as Endocannabinologist. Yeah. It's that important that it will be incorporated into med school, we will have specialists. And what we're going to need is people like you that are sorting through people that are just trying to make a buck, and you're able to put stuff up there that can actually help some people. So much like I like a website called examine.com. Where they vet products, you're doing the exact same thing for the CBD industry. And I commend you on that. And I want to thank you for coming out of your other other profession and being able to put your digital expertise into something to help people.Yeah, it appreciate it. You're right. We talked about the mess. I mean, what do you say 22 out of 24 products I don't know.Actually what they said was 26 to 28 to one yeah, is a fraudulent product.I don't know if you guys listen to the FDA hearing on CBD, but one of the things that kept coming up over and over and over maybe the most consistent thing was, how many fraudulent products there are out there. And it's it's bad. And I think, I mean, that's where the benefit of having the FDA regulate. You know, what can be said and what can't you know, from a marketing perspective is important because you've got people that just want to make a quick buck and they look for situations like this on a early to market, non regulated product that actually works. It is a quick buck type business person's dream. But you got to balance that with how do we vet all these products out and vet these companies. And that's what we we partner with those companies that we feel like are going to be there for the long term. And, and those are the products that we have.What I feel I like the most though about CBD takeout and this approach is that oftentimes with something like the FDA, you're right, they may try to put in some tools or mechanisms to prevent something from happening. But what ends up happening oftentimes is they block access to legitimacy. Yeah. So really, what Jeremy and his company are doing, I think, is from the inside, you're basically beating them to the punch saying no no no we've got a mechanism here. We can filter out the bad, we want to bring you the good so having a resource like that to turn to say, if I shop here this is where I'm going to find the high quality product it's no different than going to a natural grocers and knowing that every time you buy produce in there it's going to be organic regardless of the supplier Yeah. Or going to a whole foods and saying when I shop in the organic section here, I know this has been vetted, it's been tested I can trust what I'm buying here. There's lots of other reputable grocery stores I'm not just singling them out but there's a market for the market itself to police itself and they will rise.Yeah, you know where I think that's going to be particularly important at where I think that we're we're going to really take off is when the other cannabinoids start catching on when that research research starts showing that CBN CBG and blended cannabinoids because we will have already shown our community that we vet CBD companies and it's going to be the same companies that are doing the research on CBN CBG and we will be able to offer that very quickly to our customers as that comes to market.For somebody who is a former cheerleader slash digital marketer who doesn't believe that he should have get on a new medicine you are you are speaking like a doctor. And it is phenomenal. You're speaking like a researcher. What you're describing is, you understand the next wave of this. The majority of people don't even have any clue about CBD or anything else like that. But you're talking next level type stuff. Because the way that I envision it is the endocannabinologist will sit there and say, oh, my goodness, you have ankylosing spondylitis with ankylosing spondylitis. What I believe is that you need a ratio of THC of 10% CBD of 30% CBG of x and this is going to be the response you're going to have in order to be able to control your immune system. And we're not gonna have to put you on prednisone would not have to put you on infliximab, but Remicade or Humera, and the future of this is essentially real medicine. And when, because what I would like to do, I mean, when you sit there and say I love the fact in the very beginning of the show, you said, Well, I made enough money doing this other thing that I can focus on my other thing, I would like to make enough money doing my thing that I can sit there and do my real passion, which is research. I love research. I want to be able to sit there and say, Jeremy, I believe that I'm going to do this study, we're going to pay for it. We're going to look at what these different Endocannabinoids do in different diseases, and then I can go to somebody like you that can actually promote it in an ethical, honest way to say that this is the research that's there. If this is something that you believe that you need, that's awesome, but we've done our homework on the products that are there. And quite honestly, if it's OhHi energetics if it's elixinol that CBD line with CBD plus, these are all really good companies. Yeah, we need to get the word out. It doesn't matter who's putting it out there. Yeah, it's Not a competition anymore. It's a matter of let's start helping some people.Yeah, yeah, man, you're hitting on a lot of a lot of great things that I'm it. I'm wondering how how deep I outta go into this, but you talk about ethics. And I mean, that is a common thing that you hear in business people talking about, we want to do this ethically I'm to the point that if if we can't do it ethically, I'm not going to do it. And that that really becomes a complicated issue. When you look at you gotta pay your bills, you got it, you have to decide, do we make this dollar or do we do this ethically, and I just got to the point where if I'm very solidified in that fact of the company will grow if we are servicing enough people in the right way. And when you talk about doing that research Doing what you're passionate about, and doing it ethically. I just encourage you to stick to that. And things, things will happen to reward that in a way because we need that research from from a humanity standpoint, we're our, our society is so written with anxiety, and I mean, everybody it is, I hate to use extremes, but everybody hates each other because they're on this political side or that political side and I'm just tired of, of our society being that way. And I'm susceptible as well. And and so, I, you start sparking, sparking these emotions in me when you start talking about those things of ethics and what you're passionate about and all those things because, man, our country has, has falsely said that We we were on this righteous pursuit and and we've said it for a long time as a country. And honestly, I don't think that was the deal. I think we were in the pursuit of of making money. And so I'm hoping that we can heal as a nation and go back to, to this place of being responsible and helping each other out even when it might be detrimental to ourselves. And what I mean by that is, okay, I'm going to help you even though that's going to cost me money in a way where I can't pay my bills. So stepping out there in a way to help each other like we should be doing.That reminds me of the book Atlas Shrugged by Imran.Imran. Yeah.The definition of altruism to actually do something where you are not going to benefit. Yeah, that is the definition of it. So...Big shout out also since we've been talking about CPG to Dan and Kayla Wright from Green Sweet are a small company that is started just out of California and they're going around finding all organic land from California is as far east as Texas to plant basically hemp and cultivate before it grows too big so that they can simply go to CPG. Because they want to do research. Yeah. They want they are dedicated research and they're going to work with OhHi. And hopefully us as we go forward.It's one of those things this is like this is it's it's super cool that we're setting up this conversation because that means is essentially the first time we've met but it's crazy. How many people want the same thing. You want your kids to be healthy. You want to live a healthy life. Yes. You want to be able to pay your bills. Yes, you want to do all this stuff, but the majority of people want society to rise as a whole. Yeah, we really want to help and I think that one way that we can do this is to focus on the endocannabinoid system. Yeah, and just get everything back in balance. Yep, that's my thing that I tell all my patients The endocannabinoid system. What it does is just mediates everything to get everybody back in balance so that you're not over firing. It's not a big nerve that's setting off.Yeah. Yeah. The cool thing about that is, you know, Eric, you were talking about the feedback that we get. And yeah, I think CBD might be getting a bad rap for all it fixes everything. But the weird thing about it is when you balance your body, I mean, I was talking to somebody the other day that said that they had male male pattern baldness and they said, Well, my hair started growing back. And you could you could save what the CBD is not going to do that. But the thing is, is CBD is putting his body back in balance to do what it was supposed to do. So his body was just out of balance in a way. Alright, so I mean, not to not to interrupt, but a great example is when I see patients and they're like I've have I'm having weight loss. I'm having a hair falling out having this and that and then we can get to the point where you realize oh, you're not sleeping well, you're stressed. Your your thyroids out, and then we fix that. And then everything starts fixing itself. They don't think anything of that, right? They're like, Oh, well, we got your thyroid back to normal. Yeah, your hair is growing back, you're sleeping better. You're having normal bowel movements. It's all good. They're like, Oh, yeah, my thyroid's back to normal. That's cool. And we did that through nutrition usually, yeah. Because I'm not a not an endocrinologist. So I don't just you know, but we usually do it through nutrition and you know, change in lifestyle. Nobody thinks anything of that and, and then when we do the endocannabinoid system, ahthat can't be true, yeah. Guess what? Yeah, it essentially is like a hormone. Yeah, it's essentially it's a system. The endocrinology system is everywhere in your body. Your neurological system is everywhere in your body. The endocannabinoid system is everywhere in your body. Why can't it just come back to balance and cool things started happening? Yeah, it can That's awesome well I think that'll do it for our first podcast from the first studio our first our new studioWell we want to we want to end with one, okay. We always want to end with something with our guests. Yeah. So Jeremy tell us one last time about CBD takeout where they can go to find you where they can find you on social media the usual stuff and why supporting you supports the industry and helps people.Yep. Right on. So CBDtakeout.com. You can find us on Instagram CBD underscore takeout Facebook CBD takeout you know all the normal stuff you can find this if you go looking for us. We are a marketplace that vet CBD companies and provides the best slash high value CBD products and that has many different forms. You know, tinctures, salves, all that good stuff. And in one fantastic, easy to use website, one place to find that you know, going back to the the benefit of the industry is we're doing the work you know speaking to you customers. We know that you're overwhelmed with trying to find a good CBD product first you're like, what does this do? Second, why is it everywhere in the gas station or whatever? Third, how do I choose the product for me? I would recommend you go to CBDtakeout.com, we're doing that work for you and constantly reading laws, reading science, reading the research and vetting these companies to provide great products for you to use.It's awesome. I got one question for you. I've been looking for the best CBD toilet paper. Do you guys offer that?Yes and it's made of goats hair.No, no mo nomo hair.There you go. That's great.So and I wanted to add one of the things that you said when we first met to your website that ya'll wanted to add and the reason why I wanted to get you in and and Ken here together is soon ya'll like to be able feature educational videos. Basically walk people through the application of CBD and what to look for. Yeah, certainly. And we're about to launch a video series. It takes time, you know, coming from the technology world. I don't have video, well, I didn't have video equipment. I didn't have all these microphones and all this stuff and so acquiring that and figuring out what equipment do we need and, and hiring a good editing company and because if you outsource everything, you guys have probably figured this out, you lose your voice. And and so we figured that out pretty early that if we had a marketing agency doing everything for us and videographers and everything, then they were telling us what to do and they were chopping it up in a way that we didn't necessarily want to do. So we have decided to slow that down. Everything is done in in house and then we we will dictate, you know, hire out certain things but it takes time to build all of that but we are coming out with a video educational series. And y'all frankly, let us know what you want to hear we we don't want to just be talking about stuff that we're interested in. We're directing this to you guys and to educate, educate our customers, so let us know.Well, I'm going to offer this to CBD Takeout that the thing that we can offer Eric and I, which is science, yep. And so, you know, if there's, we have access to graduate students that look up a lot of articles. I just got into several articles today from our favorite graduate student, and she sent me some crazy stuff on the endocannabinoid system and autism and you just eat it up because then you start breaking it down. What I want to do is I want to say the how and the why that these things can happen. Yeah, for instance, it isn't that oh male pattern baldness gets better with this. I'm going to say, here's the markers that get improved when you take CBD because your own endocannabinoid system will decrease the inflammatory brain markers aisle 12 aisle 23, TNF alpha, TNF beta and it's done in animals and it's done in humans and they look at it and people go there's no research. No, there's tons of research. Yeah, there's tons of research, you just got to put the work in and we fortunately have somebody who's a rock star at finding this kind of information and I get daily emails that when I have my next job when I make enough money and I can do what you're doing into the thing that I really want to do, then I can sit there and spend all day looking at it but that you're exactly right. So our our, our gift to you, we want to make sure that CBD takeout is successful. And we want to help you in any way. So if your if your audience if your listeners ask questions, we want to make videos for you CBD takeouts and not for a product for you that we can offer some help for your listeners and explain different things.Yeah, yeah, fantastic. I think that'll be great because one of the things I mean, it's why I'm here is there, there are people out there that don't want to be guinea pigs and don't want anecdotal evidence they want science and frankly, I don't blame them and, and so that's one of the things that we want to get better at is providing hard science as it's coming out and being on the cutting edge of all the research we want to be leading with with that information.Sweet. Jeremy, thank you so much for hopping on the show. So you'll find Jeremy's fine offerings at CBDtakeout.com that is CBDtakeout.com also brought to you today by Atrantil. Go to lovemytummy.com forward slash spoony save some money. But you're giving me hands here. I'm just giving hands because I'm just like oh wow this is sponsored by so many wonderful thingsThat's right. Sponsored by love, sponsored by God, this is sponsored by the world, this is sponsored by...Yeah, I wanna I want to thank lazy Sunday'z Podcast for bringing Jeremy and I together Tequila 512 casita, you can find about find out more about tequila 512 at tequila512.com. And of course, the new website for KBMD Health should be rolling out pretty soon KBMDhealth.com. If you don't like the current site, you have no one to blame but me because websites should not be built by anesthesia providers. Shitty website.Right? So Jeremy, so this is this is one of the things and this is this little piece of advice to everybody out there listening. So I have a patient who's an extremely successful business person. And the one of the things he told me was that you want to know the number one reason why businesses fail. I'm going to ask you this. What's Jeremy, what's the number one reason why businesses fail?I would say lack of execution.That's much better than me. I said lack of funding. Okay, so he said, they never jump. They never jump off the dock. Yeah, there's essentially execution. Yeah, they never just jumped anf go well, Eric and I are jumpers and sometimes we don't build real build the best thing.It's a long way down. A really, really long way. Yeah.And then when you smack, then what do you do? There's a quote from Mike Tyson that that I love. And he said, I'm gonna mess it all up. I'm paraphrasing. Everybody's tough until they get hit in the mouth.Everybody has a plan until they get punched in the mouth. That's his classic quote. Yeah, I mean. Everybody says I'm gonna do this, this and thisNow, what do you do? So jumping, I'm also a jumper. And I've had to learn over time when you bounce now what do you do? And I've learned to think before I jump a little bit, man, when I was young, I would just jump. Here we go. You gotta jump. I mean, that's how you start, but then when you bounce then what do you do? How do you execute from there on out?Well the beauty of this is that I'm not a jumper by nature I'm a I'm truly like and it's funny when I think about it I'm truly a scientist by nature I've been Yeah, I've been a nerd my entire life. I've been in healthcare my entire life. And then you meet somebody like Eric and you get inspired and then we developed a product called Atrantil. And all of a sudden you realize that you become a jumper but I'm like, does not necessarily parachute but it's more Mary Poppins. My umbrella is science. Yes, well, I'm gonna jump but I'm pretty good idea that because of what's already been discovered what's already been shown, I'm going to land softly. Yeah, and I'm not going to do a dead cat bounce and, you know, just smack. And that's an old stock term, I think where people would sit there and say when the stock just plummets, it'll have a little bounce and that adds a dead cat bounce.  I'm not trying to offend the feline lovers and thing

Crohn's Fitness Food
Episode 33: Author Anitriss Smith, "Undefeated: My Fight with Crohn's Disease"

Crohn's Fitness Food

Play Episode Listen Later Aug 19, 2019 51:28


In today’s episode, author Anitriss Smith shares her 18-year journey with Crohn’s Disease and how her desire to help others with IBD know that they are not alone, drove her to tell her story in her new book Undefeated: My fight with Crohn’s Disease. Diagnosed in 2000 after experiencing her first flare during a family road trip to Canada, it took Anitriss 16 years of struggling with Crohn’s before she finally found the right care and treatment at the University of Michigan Hospital. Her previous doctors–despite many tests, medications, and pain killers–never succeeded in helping her achieve remission. In 2016, she was finally started on Remicade and was able to start taking back control of her health and life. She talks about the important role her husband and children continue to play in providing support and laughter throughout her Crohn’s journey. Her children are always eager to help during flares by cooking food (and snuggling) and she’s learned over the years to help her body heal by getting rest, finding peace and a quiet escape through reading scripture, and adjusting her diet. It was just last year, after spending so much time battling a disease she felt she couldn’t win, that she realized, “I’m still standing,” and with the encouragement of her husband, she began writing. After battling Crohn’s for so long, she couldn’t sit around anymore and not share what she had learned and experienced. The process of writing was not only therapeutic, but was her way of being able to help others going through the same thing. Battling IBD is not just a physical fight, but a mental and emotional one as well. “I am a woman of faith and family,” she says in her book. “I’ve had many trials and challenges with this disease and its effects. Now, I am taking charge of my health and future. My goal is to encourage others to unite and in turn challenge others to do the same. Together we are UNDEFEATED!” Anitriss’ book is available on Amazon or through direct sales. If you’d like a signed copy, you can direct message her on Facebook (she accepts PayPal, Cash App, check or money order) or if you’re in the Flint, Michigan, area, you can bring your copy to her book signing: Undefeated: My Fight With Crohn’s Disease Saturday, August 24, 20191:00pm-3:00pmTotem Books620 W. Court St.Flint, MI 49503 https://www.amazon.com/Undefeated-My-fight-Crohns-Disease/dp/1075984300/https://www.facebook.com/AuthorAnitrissSmith/https://www.facebook.com/anitriss.smith  

Crohn's Fitness Food
Episode 28: Rachel Epplin-Rincker, Part 2 – Nutrition, fitness, medications, and advocacy

Crohn's Fitness Food

Play Episode Listen Later Jul 15, 2019 47:08


In part 2 of my interview with Rachel Epplin-Rincker, she continues to share her journey with Crohn’s Disease and how important both nutrition and physical activity were, in addition to Remicade, to helping her achieve the best health of her life. We pick up right where we left off on the last episode and Rachel gets right in to talking about how her diet has evolved over the years and what she eats when she’s experiencing a mild flare vs. when she doesn’t have any Crohn’s symptoms. She even talks about how she was able to retrain her gut–a process that took a few years–to be able to eat many of the foods she enjoys but was not able to tolerate at first with her IBD. She focuses on food quality and moderation more than restricting any certain types of foods and is now able to give her body the nutrients it needs to thrive. The energy she gets from eating healthy definitely fuels her activity. A runner since the age of 5, she still enjoys mixing running in with her strength training workouts. She talks about her decision to slowly build a home gym that gave her peace of mind when working out with Crohn’s and also eliminated the need for going in to a public gym with a compromised immune system. While her workouts are intense and consistent, she has also learned over the years to listen to what her body needs, whether during times of flares or sickness or when she was pregnant and required rest. Finally, she talks about what it’s been like to be an active part of the IBD community after spending so many years undiagnosed and not having such a far-reaching support system. She talks about the importance of raising awareness for Crohn’s and Ulcerative Colitis and urges patients who have access to a Gastroenterologist who specializes in IBD to seek one out. Follow Rachel on Instagram @rachelfitmom

Crohn's Fitness Food
Episode 27: Rachel Epplin-Rincker, Crohn's Warrior, shares part 1 of her story of misdiagnosis and infertility

Crohn's Fitness Food

Play Episode Listen Later Jul 8, 2019 51:57


In today’s episode, Rachel Epplin-Rincker shares her Crohn’s story and how she went more than 20 years undiagnosed. With symptoms from the time she was a baby until her early adult life, she was dismissed by doctors, believed to be anorexic, and slowly worsened as the years went by. Finally, in her early 20s she demanded a colonoscopy and the diagnosis was conclusive: Crohn’s Disease–her colon was actually collapsed and inflamed so much that the doctor couldn’t even finish the colonoscopy. She was immediately put on medications and eventually started treatments with Remicade that finally put her on a path to healing. Through the 10 years since her diagnosis, Crohn’s continued to give her challenges. She talks about how it affected her fertility and shares her experiences with IVF treatments–including a miscarriage and later a healthy boy–and then how, when her body finally reached full remission and a healthy state of being, she was able to conceive naturally. Rachel shares her advice for women with IBD who are considering getting pregnant and talks about the importance of expressing your concerns and discussing all your questions with a doctor who is understanding and acting as a partner in your healthcare. Find a physician who will present you with facts and data and help you in making your own decisions along the way for balancing IBD and pregnancy. She also encourages patients who are newly diagnosed or still undiagnosed to keep track of symptoms and document everything that you are experiencing to become a better advocate for yourself and get the care you need. We’ll pick up with part 2 of Rachel’s journey in next week’s episode where she shares how her journey to health continued after beginning Remicade and the birth of her babies, and how both diet and nutrition played a significant role in helping her achieve complete remission. Follow Rachel on Instagram @rachelfitmom  

Crohn's Fitness Food
Episode 16: Meghan Cary Brown, Crohn's/Colitis and Patient Coach

Crohn's Fitness Food

Play Episode Listen Later Apr 22, 2019 57:29


Today’s guest is Meghan Cary Brown. At 27 years old, Meghan has lived 10 years with active disease, 13 years with indeterminate Crohn’s/Colitis, and 3 years with an ostomy. But IBD can’t stop her. In that same time, she’s also gotten married, graduated college, lived in four different states, travelled abroad, adopted a zoo of fur babies, and–most recently–landed her dream job as a Patient Coach. As an 8th grader in Middle School, Meghan began having her first bouts of severe diarrhea and IBD symptoms, but doctors dismissed her as just being a nervous child. After about a year, she received a Crohn’s diagnosis and started down a path a trying various prescriptions from oral medications, Methotrexate injections, and biologics. Too sick to stay in school, she was home schooled for the next few years. During the summer before her sophomore year, she finally responded to Remicade and went into remission. With her parents’ encouragement and being concerned about the possible side-effects of biologics, she went medication free and did well for about five years with the help of a homeopathic doctor. But, during her junior year of college, life and stress caught up and she was back in a Crohn’s flare. Meghan shares what it was like to start back at square one and how she got through the struggles and kept a positive mindset. Then, after finding relief with Entivyo for a few years, in 2015, her doctor told her she had high grade dysplasia–a precancerous colon. Coming to terms with the fact that her best option was to remove her colon and rectum, she chose to have the surgery for a permanent ileostomy. Looking back, she has no regrets and the ostomy has changed her life for the better. Listen as she shares what the recovery process was like–including the initial learning curve she battled with caring for her ostomy–and the importance of talking with someone who’s been through the same thing. Now serving as an advocate for IBD and as a patient coach for 11 Health, she shares what it has been like to not only help others, but how it has also helped herself heal. She encourages every IBD patient to reach out and talk with someone, to take a step back and not worry about the little things, and to take care of yourself every day. Find Meghan on Instagram: @emc_brown Learn more about 11 Health and Patient Coaching:https://www.instagram.com/patientcoaches/http://www.11health.com/coachhttps://soundcloud.com/11health  

Crohn's Fitness Food
Episode 14: Luciana Podschun, 30-year Crohn's Warrior

Crohn's Fitness Food

Play Episode Listen Later Apr 8, 2019 35:07


In this episode, Luciana Podschun shares her nearly 30-year journey with Crohn’s Disease and talks about everything from international travel, the support and love of her husband over the years, and how she doesn’t let Crohn’s stop her from living her life. Luciana grew up in Brazil, has lived and traveled all around the world, and now resides in California. When she was first diagnosed as a teenager, she weighed 80 pounds and didn’t know anything about the disease. She wrote to many different U.S. universities searching for information and received a lot of support–one even told her to write to the Crohn’s and Colitis Foundation, which led her to writing to a pen pal and building lifelong friendships (for our young audience listening, pen pals are what we had before social media!). In the late 1990s, biologic treatments were finally an option for Crohn’s and she began Remicade in 1999. For a few years she did very well, but in the early 2000s her symptoms steadily got worse. Finally, in 2016 the chronic inflammation and risk of cancer was too high that she underwent surgery and became a permanent ostomate. It was an eight-hour surgery with many complications afterward (a retraction, adhesions, obstructions, and stoma hernia) that left her very weak and barely able to walk. But, the surgery also gave her a second chance at living. She talks about dealing with depression, the emotional struggle, and the encouraging words of her husband who told her, “Luciana, you can’t stop being the same person you’ve always been. I’m in love with the person who is positive, likes to do things, who is brave, and who likes to live her life fully.” This was her second chance at living and after accepting her new body, things got better. She still doesn’t let Crohn’s stop her from enjoying life. Little by little her old self came back, she began finding ways of dressing up with the bag and feeling sexy and beautiful again. Mr. Crohn (as she calls it) is a part of her journey, but he doesn’t control it. She now shares her story to help other women who are going through the same thing to show that you can live your life, even with a bag. “We never know what’s going to happen tomorrow,” she said, “don’t be afraid to live your life.” More about Luciana:Blog https://meandmrcrohn.wixsite.com/mysiteInstagram @meandmrcrohn  Facebook https://www.facebook.com/meandmrcrohn Read her article for Stoma Tips Magazine here (pages 30-31)Read her article in Ostomy Connection online here  Order the Stomawise calendar here, she’s Miss June!   

Crohn's Fitness Food
Episode 12: Elizabeth Alvarez, "The Dancing Crohnie"

Crohn's Fitness Food

Play Episode Listen Later Mar 25, 2019 63:50


Today’s guest is Elizabeth Alvarez, also known as The Dancing Crohnie. Elizabeth was diagnosed with Crohn’s disease in 2011 at the age of 21. Since then, she’s described her journey as one wild ride trying to attain remission.  She’s been on numerous medications–including included Remicade, Entyvio, Humira, Stelara, Prednisone, Dilaudid, Valium and many others–and is now pairing conventional medicine with non-conventional treatments and organic lifestyle changes. Elizabeth shares her journey in pursuing a career in professional dancing, how she gave it all up when she experienced the worst flare of her life, and how she’s regaining her health and finding her way back to dancing. She relies on the expertise of her Gastroenterologist, her Naturopathic Physician, and a Dietitian to help guide her in her healing journey. In this episode, we talk about the importance of diet–including suggestions for cutting out known inflammatory foods like dairy, gluten and sugar–and her latest addition to her nutritional protocol: celery juice. (http://www.medicalmedium.com/blog/celery-juice) She urges every IBD patient to learn how nutrition can play a role in IBD management and encourages everyone to be an advocate for their own health. Follow Elizabeth online: BLOG: www.thedancingcrohnie.comCheck out her blog for articles, tips, and tricks for navigating everyday life with Crohn’s and Colitis. SOCIAL MEDIAInstagram @thedancingcrohnieFacebook: https://www.facebook.com/The-Dancing-Crohnie-517797962006260/

Gut Check Project
Shawn Bryans, CBD, Medical Marijuana, & Hemp Cultivator - COO OkieHerb

Gut Check Project

Play Episode Listen Later Mar 14, 2019 117:15


Shawn Bryans, VP of operations at Green Tree Medical and Chief grower and cultivator for Okie Herb discusses the benefits of CBD, medical marijuana, the variety of customers from the elderly to PTSD veterans, the new laws and landscape in Oklahoma, and how "Bud Tenders" function to deliver great care to consumers.https://okieherb.comhttps://kbmdhealth.comhttps://gutcheckproject.comNancy husband and wife may kiss the bride connectivity care whenever you need video chatting with the doctor right from your phone so I don't need stitches thank you Dr. United healthcare health plan benefits may vary fantastic second episode of the gut check project and we have our inaugural guess this is going to be a fantastic show on super excited about this I'm pretty pumped also so today we have this is episode number two of the gut check project brought to you by your host Dr. Kenneth Brown and well we really appreciate everyone but Joyce did you know we actually have feedback from our first show actually open content by love people I thought that you and I were just talking to each other the whole time as it turns out some people actually listening what you what you know beyond my mom beyond my wife your wife we actually had some of the people who watch that was really cool hate one of the things that we handle in terms of questions was can I take John Teal and do I need to continue taking probiotics or prebiotic's may want to dress like so there's lots confusion around these terms prebiotic probiotic all the prebiotic is on digestible food source that your bacterial breakdown so fiber is a prebiotic okay so the skins of vegetables and fruits are prebiotic's probiotics are the good bacteria that people want to take into replenish your micro bio the reality is when you're taking out trying to you you don't need to take a prebiotic or a probiotic in fact the molecules known as polyphenols are actually a form of a prebiotic they go to your: the bacteria will break it down into beneficial things so essentially and not to be too confusing but you're basically taking a form of a prebiotic by definition by taking out front feels no it's not necessary to take a pre-or probiotic if you feel better on the probiotic I say continue to take it if you do not feel better than you might want to hold off on that so if last week have your listener and you're curious about arch until you can learn more@lovemytummy.com/spooning that's love my tummy.com for discount use forward/spoony also just a reminder if you ever want to keep got catch up with Dr. Brown and what I was doing has a brand-new website called KB MD health.com so it is only a week old there might be a bug or two in there there's actually a probably a lot of bugs and there have changed and I encourage all the feedback if you don't like the language of going to change the wording is a couple pictures of myself that I would change but you know we have to do what we can do and get things up because that website is there to give information about things that we know that at least my patients are swimming towards us and asking questions about what you have all kinds of information on CBD on got health on sleep on brain protection on everything it just a platform so we want to get up there and also to get access to people to get high quality CBD to get access to upfront you and so on so yes there we encourage feedback hit me up tell me you're not a English major are you Meno English majors yeah me bad at language also so basically Eric and I made this website and there's probably some grammatical errors we would love we learned about it sooner than later I know what you're talking about but I do check out KB MD health.com because there is a lot there's got to be resourceful there's lots of research there is a store where you will find the brand-new KB MD CBD as well as trying to heal and will have other things added to the store as we put research behind yes recent research is one of the things I'm most excited about where you have a guest on today and were to be talking CBD in the cannabis industry and all of that supersmart guy Sean Brian's was just talking from outside not just I love historian you guys gotta stick with this show today because it can be super exciting but one of the things I want to do is I really want to do clinical research on my patients less early research I just want to track the results and were to be putting those kind of things first on the website as we await publication and then once we get published then will go and replace that but anybody go to that website is going to see the white papers first before while they're being submitted for publication way it works you submit it takes a few months this is just a way to get access to things much sooner much sooner last mention here a quick for a sponsor that we had for the show which is down weed is happening now with the medical director of Bridgestone and happens to be Dr. J Perry also a gastroenterologist at the top of the hour you probably heard if you're listening already mentioned ridges own and it was being rented by the late great Doc Thompson so I shout out to Doc Thompson again thanks so much for having us here the team chef Patrick Ron everyone couldn't be happier to now start our second episode of the gut check project on spoony radio so we we did not get pulled off the air last week which outcries and actually said you can come back and do another show I got another shirt is amazing so it's been a week before we jump into all the cool stuff to talk about today what you been up to man for a week it has been a week so last week my oldest son the whole family my youngest son the wife and I took tons of family down San Antonio we live in North Texas if you are familiar that's 5 Hours Dr. S. went and I saw my oldest son compete in the state basketball tournament they did well and dad and after that we it inquired when the whole thing so we decided to take off and enjoy some family time out in San Diego we do know I logged around couple hundred bucks I guess online scooters if you are looking for a way to enjoy an urban environment written lime scooter similar while you heard did you get a chance to jump into one of the Navy seal bug training techniques of water cold immersion we did decide not to do that after we put on a wetsuit and tried to serve tennis: water is not warm at all wetsuit is correct your wet your wet and cold and then you're still wet but we did serve it just got out of there soon become fully we went to do good for you let yourself or even wow I had an equally exotic experience I had to go to which I didn't have to I went to Wichita Falls Texas because my son had a tennis tournament there and my wife and daughter went down to Waco because she had a tennis tournament there which coincidentally shot out to her Carlos she double gold singles and I won the whole tournament love that my son Lucas and I in Wichita if you've ever been there Wendy very very windy candy yet and it was raining so we had tons of rain delays all the stuff I did bring my X.3 bar which you will be writing about this also but the X.3 bar is a portable exercise system developed by a PhD named John Jake wish and I had a long conversation with him not to long ago and he's done some great research showing how variable resistance and volatile bottom line is I sat in a hotel room worked out watch rainfall pendulum was probably as wet and cold as you yeah I without question down if you notice now the Wichita Falls in Texas actually is the region that varies the most from year to year in temperature fluctuation it has the biggest swing I believe throughout the entire state shock about the back me up on this by the time he gets in here but it literally has the biggest average temperature swing throughout the entire state that little region at their out of the Red River and – describe a little bit about what the X.3 bar looks like because if you had never seen this thing is really cool it's very portable it's equipped with bands but has has a resistance motion that you know if you're just looking anything that looks weird when he tried it will wear your ass down since in this actually Dr. Jake which gave me a code so that our listeners can execute a discount on ice just when you go you get it go to X.3 bar.com and then put in code KB MD and you get a nice discount there the other science is pretty interesting I'm mobile hacking this is like one of those mobile acts that you can do show is portable you know there's no excuses for not working out take about 10 minutes and you're done so you break a sweat you will think that you won't but you will break a sweat in fact if you go to the our Instagram at KPMG health is no need to do the resident we need to do this because you can see the big man Eric over here is not doing some curls with the X.3 bar actually got several videos of the X.3 bars so about someone else's biceps to do that she actually had to stop mid workout because he was getting too big yeah knows what about changes wardrobe so that would build fitness shared real quick any other news or notes of any to talk about for the gut check project coming up I can't think anything big of them have our first guest this week but I know that you went to where he works while Europe and Wichita Falls yeah that's right so coincidentally and we Artie had him booked for this I went up Wichita Falls right next to the border of Oklahoma Oklahoma just recently became a I'm to say the word wrong but medical cannabis legal state yes is that term that made Sean to clarify we John. His unit tells all about about what goes on yes I went up there and took a look in our CBD product is in that is in that store it was really cool to see all the hard work that we've done to educate and get things moving and so if you get a chance Oklahoma is one of the new states to start the medical marijuana interestingly enough that I do find it kind perplexing that taxes being such a large state watches the bordering states open up a casino or open up the opportunity for medical delivery cannabis or CBD and essentially date it's it's Texas citizens that more or less come support that industry and I'm sure this will be the same until Texas decides to participate I am very familiar with that because I'm from Nebraska originally were that's exactly what's going on in Colorado once I won the other right I would as the casinos Colorado courses the cannabis industry in Nebraska has chosen to be very strict on that so not surprising to me that a state can have neighboring states with little bit more liberal or differing views sure now I understand well I believe listeners will be going to try to start doing is giving over the format in our first hour so it this point time were going to talk about health news as a relates to the gut check project in KPMG health and you can learn firsthand why I always like talking to Dr. Brown in terms of how he keeps up with what's the latest trends and the latest relevant news in health so this last week and we got a little bit of experience with what were going to talk about but it just so happens there's a lot of research into the fasting mimicking diet and what it can do for you and I'm stopping that you can take over so super interesting a study was published just last week about the fasting mimicking.now with the fasting mimicking diet is is this is developed by a fantastic researcher named vulture long ago and what you do is he figured on animals that if you give a caloric restriction meaning your to take 1000 cal a first end and work your way down to about 10 to about 10% of your normal calories in a very specific ratio of fats proteins and carbs that you can trick your body into believing that it's in a fast and what that does in humans he showed that after five days you turn on your stem cells it actually gets your old selves sick and old cells to just go away called autophagy and so if you can think of it this way your body says okay these cells that are starting to show signs of possible early cancer things like that the body recognizes that goes you go away in working to start new cells so that's the basis of the fasting mimicking diet this was developed and a company called L Neutra has developed a product called prologue to sort of make it really simple for you to have the exact ratio that's have prolonged PR OL ON PROLON so vulture has been doing tons of research and you he's I follow his words Rhonda Patrick follows work through a lot of other conferences he's always going to longevity conferences and giving lectures this time something very near and dear to my heart he just published so out of the University of Southern California USC this article out of cell reports the fasting mimicking diet modulates microbiota and promotes intestinal regeneration to reduce inflammatory bowel disease pathology very long big Boring to title but here's what supercool is basically he took mice he put them on the fasting mimicking diet end date induced Crohn's disease and ulcerative colitis so inflammatory bowel disease and then he showed that these mice had decreased intestinal inflammation increased intestinal stem cells they actually reverse the disease and something else is really cool is that they improved the micro biome composition and then he actually showed that it improved leaky gut or intestinal permeability something about this moment we have a disease or chronic disease inflammatory bowel disease if you don't know anybody who has as its brutal this is what I do with my practice all the time but by putting somebody on a fasting mimicking diet you can actually reverse this then he compared that group to a water only fast this is amazing the water only fast did not do nearly as well this is rising I would not have thought that I was completely blown away because I've always I've done I did three fast this year I did 35 day fast the first one was the prolonged one I did a prolonged fast and I could totally tell when those stencils kicked in I just had a boost of energy like you would not believe next when I did I tried to can't hack the prolonged pasture and try to do it using the foods I bought and try to mimic it I did not quite get that boost of energy and then my third fast was a water only fast for five days and once again I did not get that I just woke up at like 1 AM to take on the world and so I've actually contacted the CEO of L Nutro that were extra friends with Joe on Tuesday and him I talked to said yeah because that's the amazing thing we don't people don't realize it the faster mimicking diet is actually based off of true science and animals vaulter did this all he worked out the exact ratio how many days and then after you do this you have to repeat so in this particular group we had two groups of mice one did water only and that group did not do as well the fasting mimicking group had increased the fiddle bacteria and lactobacilli which have been shown to improve so you asked me the beginning of the show what about prebiotic and probiotic I well guess what if you do a fasting. Then your body will figure out what bacteria should proliferate more when we eat it's actually an inflammatory process so every time you eat electrically little bit of inflammation in the gut by giving it a break and by doing the fasting mimicking diet your not only given your get a break but your body goes okay we can get rid of old dying cells get rid of precancerous cells and working to start brand-new ones and is proven it with these mice what is so fascinating to me is that the faster mimicking diet is so much easier than the water only diet I can vouch for that then we had which at our whole company do it and at all trying to I think we have that on our on a page would a blogger yeah I think it's right at a year ago is that's correct and I can I can say the water fast it's not the worst thing ever but it's more difficult the whenever your body decides you need to eat and he had the influx I believe it's called a Rex and it makes you think okay your ravenous and you need to eat and you have a burst of energy simply to go out and find food and I was actually somewhat envious of those who had done the pole on is the control because the and including you that point time did not have the same drive to go out and just eat yeah you are fasting but at the same time your body seem to be tolerating all the better yeah what about fasting I actually after this article got published I realize another article just really got published with a look at the different fasting types in religion and we have Ramadan we've got Jan to pour a lot of similarities to similar with the Daniel fast we have lent which I'm Catholic but not delivered probably should be fasting in a more serious way here that but it's just interesting that the fasting is could be one of the easiest life hacks ever it's amazing that so many religions had that been are are based in insomuch a agent tradition that there are lots of things between religions that actually are incredibly similar and it also comes down to asking so the reason why this such a big deal is because I have my Crohn's and colitis patients and if you do have girls or colitis or annoying but it does please share this so that we can don't help everybody with this because I think a lot of doctors are talking of fasting and so I think my little hatch here who's going to be the fasting mimicking diet plus trying to heal for the polyphenol effect and we also know that he gets rid of the bad bacteria that's growing rich and big plus CBD which attenuates your immune system right could be the magic thing so I called Joe the CEO of Elder Troy and we got talking about this and he goes I want to come down to do the show let's talk and I'm like yes let's do this this is going be fantastic so we can have a whole episode dedicated to the faster mimicking diet and the science of it and you know how people can realize that it really kind of resets and it's an antiaging thing also so you can do from home this is it something it's going to require someone to go out and get a prescription only to prescription to do a fasting and a condign somebody's have to schedule a time to do it and then commit to it and then I would imagine you being a guest urologist to be C70 make those kinds of improvements that's really all you want is the best for your patient and if they can handle that on their own and escape disease it's a win for everyone as natural natural to do it so being vultures studies it's really exciting because what he showed is it is antiaging it is anti-inflammatory and was really fun is that he also so that you have to re-feed so once you do that and you you have the discipline to do those five days of decreased cowgirl of calories and using the fast mimicking diet when you start re-feeding it is awesome because and he also show that if you do it three times in a year that is equivalent to doing ketogenic diet year-round so now that he showed that in different animal models also so for those who at their key billing manager if you struggling as many who don't struggle but if you are struggling maybe this is not turned the computer I have done it and I have fallen off of it and got back on and fallen off it's and get it's not the hot again not the hardest thing ever but the discipline to stay there if you have a family I'm anything you cook for kids then that's not what they want to do is difficult Joe Rogan had Dr. Addie on how dark a joke and I prepare the both of them to deliver talk about the how they just can't rule their diets by making humor and jelly sandwiches for the kids to cut off the crust and Joe just would just eat the crust off the course so I did that also so every time I done Quito I would I would lapse without trying to lapse I would end up doing dirty Quito church where I would build despite outspent direct all is much as I want and then later be like well sure I can have this bowl of rice yeah what you know it with but with Quito if I member correctly you are talking about lab results even on yourself that where Ed there is advantages to doing keto but if you end up doing like he called a dirty keto you might actually failure your desired results off because your body has been moved to doing fats and you've basically thrown in this carbohydrate in talk about that quick so I didn't I like to do so one of my problems in working probably get into that little bit with Sean when he comes on when I do something I go all way way so I'll try it's all just go Quito and then over period of time I didn't realize I was that I drew I'd listen to a bent wrinkle podcast like oh I need to have lentils now is or whatever you know you name it and I totally forget that that's going on so my functional medicine doctor his name is Kevin Wilson here in town and you know he practices antiaging functional medicine she took my blood and called me up his like what have you been doing and course what we were doing is messing with my diet that I'm experimenting with different supplements because were trying to develop more products right and I'm not really paying attention that I'm doing everything at once at the same time sure and all of a sudden he just like your heard labs are messed up buddy commitments and talking alike is what you been doing I was like you have enough time I been doing it all. I'm just everything that it makes it difficult to find out but that's for sure but I will say it every single thing that you have recommended to patient for long as I've known you you've tried it on yourself first I have 100% done that so I have always done it that this is this is not new I remember being a medical student and I was in Lexington Nebraska running the ER at night so I was like the only person awake in Lexington Nebraska at the time and I decided to teach myself how to do an IV on myself which is hard especially first time so let's see I've tried to stick an NG tube down myself that didn't work so well I live but I've done an art I did an arterial line on myself one time that's ridiculous yeah that's not don't don't do that don't do any of this is a matter if I don't do any but I'm just saying that I will do it so that you don't have to share pain of an arterial line is about tenfold of any intravenous line I had left there was a comment on my YouTube channel yesterday where you I posted my colonoscopy online yeah over on YouTube don't do that either and I was awake but it's hilarious actually texted the text this morning with this Abby somebody in the UK said and you'll notice that nobody cares about your but were all looking to screen his writings always get nervous that I don't you see my butt and she pointed out the second he said that Abby looked at my butt and I I've never noticed that so colonoscopy everything so if I'm not you… Come down with everything I really would never I want to try things on myself then I do a case series with patients and then I have data to tell people I was a look this will happen to me this is this group of 20 people over here that were working with athletic Crohn's and colitis communities so near and dear to my heart because I'm using a lot of different things I've seen success with them sure and don't forget the reason why we are doing a check project is to talk about caving the health which was born out of the idea of taking what you find out in the clinic are you going from anecdotal to applied science and to find out how we can actually help people absolutely and so this is cool were coming down to the I guess the bottom of the hours and the rate of the Patrick is that what you say bottom of the hour the bottom of the hour I'm trying to give 30 seconds but apparently I don't how to make a three and is okay since I can call the fountain outside 20 feet away hate that Sean Brian first at whatever you guys 11 I wish you could go some facial is take the pain out of ordering your diabetic testing supplies with diet Thrive diatribe ships the testing supplies you need directly to you when you need them best of all with plan starting as low as eight dollars a month diatribe is probably going to cost you less than what you're paying today diatribe is so convinced that you love their service they're offering your first month of supplies free simply type the Kodak DOC and checkout diet Thrive.com that's DIA Thrive.com never forgotten apparel is more than just a premium women's and men's clothing line it's a movement to remind us to where American-made and serve those who serve us our heroes never forgotten apparel gives 20% of their total sales to nonprofits that support homeless veterans and off-duty firefighters and 50% to individual veterans and firefighters in need nationwide checkout never forgotten apparel.com use promo code Matt and ATT and get 15% off your purchase have you done it did you catch a glimpse of yourself in the mirror I'm I'm one of those people you don't want to see naked IBM most of us but I mean you look and you're going to die I know I get to whatever you call it's horrible hey that's Dr. Townsend and Brad Staggs to tell you about a different way to shed those pounds this is brand-new technically been around for a couple years or so it was based on research from the University of California that said there is a molecule called OEA that's found naturally in your body produces it in the Mediterranean diet that when taken concentrated amounts it will actually make you feel fuller and boost your metabolism I lost about 10 pounds so far is immune amazing ballet school company said we can take this to market to make this great product will help you it's called grid you zone our IDU zone.com our IDU zone.com Brad's work that were comrades work for me countless other people go to read you zone.com and try today you're gonna love it read you zone.com remember that our IDU zone.com okay we're back back to the second half hour of get check project episode number two and now we are joined with our first ever guessed this is Sean Bryant Sean Salo yeah you guys doing today doing well so when Eric and I would talk about our first guest I just sent out I don't care what we talk about but I want somebody with a beard yeah I started this in eighth grade just just just fill in the patch exactly yeah when I turned 30 I look just like there some very proud of my beard for this is Sean Bryant is VP of operations at Greentree medical and you are headed the cultivation division also known as Ogier and Greentree medical and no gear was located in Oklahoma just north of Bert Burnett across the Red River Craig yes sir and you also have a on-site medical dispensary called alternative medicine great yes we do alright well tell us a little bit about what goes on yeah I think it's as one of the coolest things is your background I personally am so intrigued by that so I would like you to stop in the beginning okay well I grew up in agricultural family my parents had big textbased company in Paris Texas and so not really didn't know what I wanted to do when I graduated high school but I had a passion for pharmacy in biology so I got a Texas Tech University and I majored in pharmacy there which was the biology program then I change my major switched over to agriculture fell in love with the horticulture and and I did a lot of research at East Texas State University and Texas A&M commerce on the cotton plant graduated then I became a bag teacher built greenhouses taught kids how to grow went straight into administration became a principal did that for 20 years and love working with people so when my son graduated high school and my daughter she's a but to be a junior it Texas state and that's when I was like you know what I'll I am ready to chase my passion so Oklahoma June 26 they passed their full medical cannabis program and my wife and I were celebrating our 25th anniversary in Arkansas and we talked about 10 miles that day and I was tired she was in bed in the cabin no TV in I just typed up a quick Craigslist ad and I found three guys that were had little to no knowledge of cannabis and how we can use that in the medical field and we made a great connection and I started working with them and that's where I am right now that's awesome so I've known you for quite some time for disclosure my wife hot for you you are the first one the harder when she was a math teacher so I seen Sean is a principal I've seen him as an assistant superintendent of the school district that was down in Texas and I've seen you much like you can whenever Sean decides to do something a Zollo a.m. date from welding to out sing the guards that you value had outback from your house all the vegetables you raise chickens how did you decide that there was a need to go you told me the cell years ago there is a need for people to be able to explore the real practical application yet far beyond the psychoactive aspects of cannabis there are people out there that have a need how you decide that this is a way did you make it happen you know it really I'm researching cannabis and I'm learning about it and I'm sharing this with other people and getting into dialogue with them and these people people that I worked with people that I Matt in a prohibition state of Texas they or one of their family members had a dire need and we started discussing know-how cannabis could help them with a medical issue and so I kind of took on the position of a caregiver by being able to share information that that I gained from from research and keep in mind you know now Dr. Brown can do research and in the public but before it was something that we would just do you know talking to our friends will how did this work with you what were the facts doing a how did you feel that this you know work with this particular ailment but now were able to discuss more freely so you know that that's kind of how I Mr. quick question so you and your scientist by nature I mean with a background in pharmacology and then horticulture and then you are an educator so that your primary start of your foundation is in science then education then you get into this industry with her so much misinformation Howdy how did you approach that were you realize it's up to him you know it's almost like your moral obligation to try and get through all the clutter because that is your back on the minutes if somebody looked at you and said all I could totally see him in the cannabis industry but they didn't realize that you were a principal or rot yet just researching and educating people you know in our dispensary right now when you have a patient come in they don't know what to ask for date they they may think I need this strong marijuana that's got 30% THC but but what we do is we work with them and and let them know that that is not always the answer but you say what you say why are there instead starting check that by now some had a question about medicine and if the physician recommended to them and they don't have time to get those answers that they may have the questions outside face and said they'll go to a pharmacist and then asked the question they cannot take this with this this is just given to me is that this style of y'all that you basically interacting with people and they come in your trying to help steer them toward something that would work yeah so like the way our medical program works in Oklahoma basically you communicate with your physician hey I would like to try medical cannabis as an alternative or with your method of treatment that were currently doing and the doctor would write you basically it's not a prescription for cannabis but it's it's an okay that you can get your medical card and then you come to the dispensary and that is where we want to work with you know the patient's to find out what part of their system is is out of balance and what we need to do to help them get out get back into balance is there a term for that person Soto would like you said pharmacist sure if I go to Colorado was that since little bit more bold is the return when I walked in I need to speak with the well a lot of people call them bartenders that term came about you know right when medical and recreation and they tended the buds that were in the jars and and no new a little bit about each particular product that was in the jar sure now caregivers are though we don't act as the caregiver for that individual patient we are caregivers and so we are providing you know data and information to the patient and let them make their decision and I all white because a lot of times a patient will come in and you know asked that will what will this do if I'm taking Flexeril or if I'm taking hydrocodone or if I'm taking antibiotic you know I always suggest tell your doctor and and let me take you guys this is a trick here it's it's really neat so you go to the doctor with the stomachache normally you go and you visit with the nurse for 10 minutes takes your pulse your blood pressure then the doctor comes in and you know you spend 10 minutes maybe 15 depending on your situation or if you need a rectal in my case abstractly and that's when I stay 30s but know if you if you bring up the topic of CBD bring up the topic of the cannabinoids and tell that to your doctor say hey I'm I've been doing some research here let me take that Dr. is going to sit there for I may not had an hour conversation and the doctor has 10 patients lining up outside waiting to see him or her and he spending his time with me because he is craving this information sure he were sent from a not want to know what he knows I want to bounce ideas you know off of him and and see how I can battle better either handle my own situations or with other patients that I'm dealing with what I would say though even here in Texas where it's not legal yet because you know that but I see almost daily it seems like the openness is is there people willing to discuss something that maybe even just three years ago what going into depth on do you do you find that depositions in Oklahoma are starting to become more embracing now that it's it's legal for them to have this as an avenue yeah most definitely there was a little bit of fear in the very beginning with with doctors they thought that they would be labeled as the cannabis doctor or the lack some of them are the opioid doctor you know which doctor you could go to to get you know drugs like that can and so they there there were some that were reluctant to to even embrace that idea you know it if you if if you're discussing your health with your doctor and you know they do not embrace cannabis in my opinion I would I would want to second I would want to second opinion I'd want to talk to to another doctor what he authors like to chemically so your gastro neurologist here in Texas licensed here and I saw you specifically decide there has to be there has to be something behind the science of the CBD so comparing what Sean's talking about what a physician would have to do to to move into this movement where it's not legal what allowed you to be able to open up and say I want to find out more for the benefit of my patients so we touch on this last week Sean I just I had no knowledge the Endo cannabinoid system I don't alter CBD marijuana I was so whenever somebody is ignorant to it I don't judge at all because I just recently started learning all of this and what change my mind was I went to a conference and I bought a case very expensive CBD at retail price now I'm angry at the company but whatever should be a discount but I gave away my patients and I just waited and when almost all of them came back that I need more that's when I knew that okay there's something to this then since that over the last three years all I've been doing is looking at the science of this and of course there's not enough of research in the United States because of these different regulations and stuff but I'm seeing clinical evidence was why get so excited when we sit here talking I'm I'm thinking when you said much like the pharmacist right dear old Seinfeld episode where it I can't member who was but basically the doctor prescribed something to go to the pharmacy the pharmacist goes I wouldn't do that you do change the spelling of who had more power the doctor the pharmacist I say us three do a little YouTube skipper I'm the Endo Kanab and all adjust I hear the bartender to be the patient, recommend a certain strain and guilt for what I would do that would be a playoff of that but that really is kind words that's where the science is going with this that's what's so exciting when if a patient comes in so I went and visited your store this weekend to right next to Wichita Falls where was and Steve there was told he goes you know what's amazing is the people walking 20-year-old saying only get sweet you know old people with chains and their struggling and there like I'm the real goes here's what peers or to do for you this is awesome and video so when I realize I'm making this what Steve told me girls I realize I'm now making a difference and people's health goes I feel what you probably would and the medicine for which is to change people's lives exactly and and were surrounded by some huge military bases in Wichita Falls and in Lawton and a lot of our customers they they do not by the cannabis that contains THC they preferred the cannabis that contains CBD the high percentage of CBD and little to 0% THC you know with CBD it is it is new to me also as far is it the benefits it is huge very huge you mentioned the Endo cannabinoids system and you know I've kind of in my mind broke the broke medical patients down into into three different categories ABC a being where I want to feed my Indo cannabinoids system I'm healthy I feel good I work out I walk so, preventative it's it's kind of a preventative and then be moving into a patient that that has an element of whether it's a backache or or a inflammatory science laboratory exactly and then all the way up to our need of severe cancer and the end things where you're you're really going to have to to wage a major war with with CBD but yet that our patients that come into our facility even though you could command if you got your medical card I can sell you 3 ounces of gorilla glue which is a cannabis strain I haven't done that I have not I have an 82-year-old man that pulls up and he will buy CBD flower which is it CBD but cannabis contain CBD and THC this strain of cannabis contains 16% CBD and like .3% THC and that's what this guy buys an and loves it he he could buy no THC but the CBD is making different table does make a huge difference Steve our manager and Bud tender you know I asked him I should tell me what you think because he said cannabis user and he he picked up this bottle and he said I take it what it does for me he said in the evening I'll take a eyedropper input under my tongue and hold it my mouth for for five minutes and then I'll swallow it swallows it he digested he goes to bed he said that when he wakes up in the morning that his whole body just feels rejuvenated pop truck got up out of bed he's he's ready to go take on the day that's what CBD does in your neuromuscular system it it if you're already in that number one zone where you're just maintaining it it helps keep a you say homeostasishomeostasis it just keeps a nice even level balance at our level in your in your body and that way you you feel great when you wake up and and then other systems will start to fall into place like I want to get into it also is a move to the show is really heavy for another hour but there there are differences in CBD and when you get it and was labeled a CPD exactly and before forget X1 ass one thing you said that you are surrounded by military bases yes are these are the servicemen coming in getting good grief yes most definitely an and you know when youth historically you know a lot of our servicemen you know they coming with PTSD and and you think of PTSD as we know from guys that the comeback promote a war-torn country and Anna and they've seen some crazy stuff and and they're trying to deal with that and that is that is very true but how huge our military is there there are things that have happened in the military it could be just having a car wreck you know that is traumatizing to you while your own active duty and and so these guys you know they're there looking for ways to to deal with you know PTSD and emotional issues so one of the things we talked about that out my goal would be this you guys beating the people that are selling CBD and selling other marijuana products you can't make any disease claims what I want to do is get research so you can have published articles 1 of the things Dr. Col. Philip Blair is also a doctor of is the medical director at Alexa and also our CBD is powered by licks and always the medical director there he actually published a case series with CBD and its effect on PTSD is a full bird colonel that realize the benefits of CBD and is now working for CBD company and still seeing patients and collecting data and so were to bring him down and he's he's in a come on in the next month yeah what I really want to do it so he so knowledgeable about that and is also knowledge about the other thing that unfortunate happens in war which is traumatic brain injury and he's actually published something on TV guys and we were talking about possibly setting up a CME meeting so doctors need certain minor credits at my hospital door trauma surgeons because I really believe that a protocol of doing high dose DHA plus CBD at the first impact of any type of dramatic brain injury recent article just got published route showed that unfortunately they did autopsies on the boys that were 16 to 19 that had played football but it had shown in these they were there were unfortunately killed from other circumstances but they they are now looking at the brains looking for CTE and are already showing signs of CTE from just high school right so we know that this TBI thing is huge and I just love it that we have like a full bird colonel who is a doctor willing to embrace it you're talking about it surrounded by military bases it's a perfect marriage is a like-minded think is this essentially what you talk about Sean whenever your wanting to help he would've come to you for that help you want to give guidance that you have it's not just anecdotal I think this'll work this is it's it's this works for this ailment we want to help you just like you said you're not selling the gorilla glue to somebody just because it's profitable to you you want to got into something's gonna make him feel better that's the whole purpose right exactly and you know back on the Indo cannabinoids system the way this the CBD works it just kind of columns some of these receptors I guess it it it if if there's something that for instance on PTSD my wife was attacked by a dog about two years ago we were done in San Marcus best in our daughter and a big bull mastiff Jehovah God are yet Torah but Karen carries on a baking sheet for so it's not her fault I was a bacon on me know if done nervously if you're baking carrier don't want grandson Mark yeah well now you know she has a phobia of just dogs but there are times that I look at her whenever somebody if were in Denton walking around where it's a dog friendly town in here comes this guy with his tiger stripe pit bull that's a sweet dog she kinda moves next to me in and she is having some anxiety and CBD is a product that really does help with that and if if if we know that were going to go to Denton she'll consume some CBD and that will you know help help your wife as long as I know you and Karen is never been a skittish or anxious person and I remember that incident quite vividly and you and you're right I arrived I've heard her comment that it's unfortunate for her that that now is something that's a blemish on an experience but I've also heard her comment that Seabees actually helped her not have is anxious. Whenever we meet chal for dinner out then there are yeah and I and you know the Indo cannabinoids system goes all the way down to think 600 million years ago you know it was in little squids and and sea creatures and and still is in most of the animals today and dogs you know there are a lot of people that will buy this product CBD do not give your animals THC please don't but CBD does help with skin conditions with animals with anxiety with animals one of the number one top sellers in Colorado right now are these pet products dog biscuits yeah I see this all the time of my patients they will deftly spend the money to treat her pants and not uncommonly will not have the money for their own medicines right but they will make sure that the pets are the words on my PTSD I'm looking at all the articles were going to be publishing here soon we've got autism and CBD we got CBD and IBD we got a full review of the end of cannabinoid system working to do PTSD and CBD in these blogs are all about science with references so that you can just hand them to people go oh here's this you look at were not making a claim but you can do your own homework just like you did were you felt that moral obligation to get out there and be a caregiver now you are actually going to have to educate in a way without making claims in my opinion is as a doctor the best way to do it and as an educator is to give references exact this is not my opinion this is just based on these this whole process to bring up Dr. Blair's name again that's actually one of his biggest calls is how do I end up taking my research and make it more applicable to the VA and to the basis because these are the gentlemen who are fighting for our country abutting a lot of the line and often times and they go to that system that machine the options are limited theirs is not it is obviously not of counseling the talk button and in the news today but oftentimes it's just to the prescriptive therapies and not to CBD that actually could be making a difference one yeah absolutely I was just talking to him we were I have a friend in Rich Hagedorn back in Omaha he's a retired 30 years in the military and him and a group of guys have started a alcohol company called soldier volley liquor and we would talk about that how they give back to the servicemen and I'm like when we got have done show we'll talk about this I think the veterans are one of our biggest populations that we can really help and I didn't even realize that you're surrounded by military bases where they are they are seeking you out exactly right yeah and and and were therefore we we want to help on the the side effects are just zero that I've seen with using CBD and compared to what they have received from the VA hospitals that cause horrible horrible side effects in these guys they they realize that they're there saying that their spouses are saying that and so they're looking for you know some some treatment that will help them mean everything were talking about comes down to inflammation PTSD information is hyper firing of nerves inflammatory bowel disease the fast mimicking diet that help these mice that is an autoimmune issue what I really would like to do this next part of the shows let's geek out I mean you got a background we can get into the end of cannabinoid system let's clear up some of the confusion let's talk about the other things full-spectrum terpenes blob about the sound sciences but let's let's bring back to level so that when someone walks in your store they listen to this or you can recommend them to listen to it there you know what they're getting just a resale because we are reaching the top of our or just a moment but this is Sean Brian's he is the vice president of operations for alternative medicine newly opened here in Oklahoma and as any other job websites yet we do have on our Instagram is Okie okay I_earth and we also have alternative medicine okay to grant alternative medicine okay on Instagram will see here in just a moment for the next hour also it's funny shows on-demand at spoony.this is the only 24 hour take anywhere platforms dedicated to food and fun career spoony this hour from Townhall.com, editors hope you have at least some information from the black boxes of the doomed Ethiopian jetliner by days end those devices now being analyzed by experts in France here the US FAA acting administrator Daniel Elwell says his agency had to investigate for ordering all 737 Max jetliners grounded it is in our minds now link that is close enough to ground airplanes he was on NBC's today show a former Texas congressman joins a growing field of Democrats vying for the parties 2020 presidential nomination Democrat Betty O'Rourke became a political sensation during his 2018 bid to unseat Texas Sen. Ted Cruz find ourselves by who or what we are getting sore afraid he lost by about 3% but was immediately mentioned for higher office Texas political analyst Jay Iris is more than 20 other Democrats are eyeing the White House works already mobilized younger voters and raised to record money with alive and gritty social media presence of work spends three days now campaigning in Iowa I'm Jackie Quinn as the British Parliament launches into its latest fracture debate president from promising enhanced trade with the UK if and when it leaves the European Union as the UK struggles with bricks at the president is holding out the promise of negotiating a large-scale trade deal with the United Kingdom he tweets the potential is unlimited it's not the first time that Mr. Trump has suggested this last month he told reporters that the US is going to be increasing its trade with the UK very substantially as time goes by White House correspondent Greg Clarkson Wall streets the Dow is down about 24 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whatever all it's horrible hey that's Doc Townsend and Brad Staggs to tell you about a different way to shed those pounds this is brand-new technically been around for a couple years or so it was based on research from the University of California that said there is a molecule called OEA that's found naturally in your body produces it in the Mediterranean diet that when taken concentrated amounts it will actually make you feel fuller and boost your metabolism I lost about 10 pounds so far is a mere amazing Valley school company said we can take this to market to make this great product will help you it's called would you zone our IDU zone.com are IDUs zone.com Brad's work does work for Brad's work for me countless other people go to read you zone.com and try today you're going to love it read you zone.com remember that our IDU zone.com hello and now we're going to start our number two episode number two we are still joined here by Sean Ryan of alternative medicine vis-à-vis the operations of that and that will clear and just a quick reminder start of second hour if you are interested in picking up your own are trying to heal just go to love my tummy.com/spoony use discount code spooning for some savings for yourself and then of course if you want to check out KB MD health CVD you can also go to KB MD okay BMD health.com or maybe somewhere else you go extra you could come over to Oklahoma and pick up some KB CBD oil when we saw this product in our store when when Eric and I met I immediately fell in love and and the first thing that that jumped out at me was you know having Dr. Brown's name on the bottle so many of our patients that command our dispensary that's the first thing that they asked is not what a doctor what a doctor recommend this what is what would end in a lifetime just kind of funny they say what would my doctor say about me using this and that's when I'm likable don't talk to your doctor tell your doctor what you want to do ask your doctor but this particular product that's backed up with with research and an extensive studies we we wanted to be a part of this we wanted this on our shelves the the other thing that that really jumped out at me is how this product was made how it was manufactured how they did the extraction process y'all use a process called supercritical CO2 extraction so cannabinoids and that are on the Kent cannabis plant they are oil soluble and they are alcohol soluble and so historically they would use some nasty chemicals like butane and propane and they would blast that gas which in a liquid form through through the cannabis extract the the all of the cannabinoids and then try to remove some of the petroleum products from that crude oil and in California they do a hunt of testing on that and California is not happy with the trace petroleum products that are still in the considered a contaminant behind it is a contaminant and some of the extraction method they actually feel that that is the containment sure can be yes alcohol so another way to extract from a cannabis plant you can take and back in the day they use things like acetone in isopropyl alcohol's and and some alcohols that that work food grade like Everclear for instance hundred 90 proof Everclear that can be used to extract cannabinoids from my cannabis plant and and do a full CBD extraction now they tried to evaporate that alcohol that that's also an end they can't sure he can't get all it all out yeah I have taken not this product but I've taken other CBD tinctures that staying real bad under my tongue some people like that staying Carlock taking of shot of vodka over you know some type of alcohol drink for me I do not consume alcohol I find it not not always II use to like alcohol but I I don't like it anymore and when I'm treating a patient I don't want to recommend a CBD tincture that has alcohol in it or other nasties in it I want to recommend a clean extracted product that use supercritical CO2 let me answer the question have you seen certain products that said possibly CO2 extraction put on your tongue burns basically mislabeling gallery itself is a little bit wild West right now most definitely met and you know I've had patients come to us and say yeah we bought this said at the jiffy mark down the road in and it doesn't work it doesn't do anything in and I look at it and you know a lot of these products were were made in India or in China and hey guys I it may be the real thing but these guys and and we have other CBD lines in our store also that are that we know the growers trip and just like your guys we we know where this plant came from we know that it was tested we know that it was tested for pesticides we know that that you know it was tested for levels of THC or CBD or other cannabinoids that are in it when I talked to Steve last week whenever we were entertaining the idea of moving KB MD CVD to I alternative medicine Oklahoma the very first question he said is we can't shelve this without a authenticated COA certificate of analysis and can you may want to talk about this why did you partner with Alexa and all-knowing it that there were certain parameters that you knew you had to meet so knowing that the industry itself so let's back up and just look at the supplement industry so my my initial background was in clinical research during pharmacologic studies and then I Neil found a few holes there we figured out we could do something natural to fix people and that's how we develop doctrine until once I get in touch until I realized holy cow the this industries people mislabeling their making claims or doing things so knowing that if I was really get into the CBD aspect of medicine I just wanted to make sure that I went with a company that was completely on the up and up very open and make sure that they had complete sourcing it was an organic farm they could naturally extract which of the supercritical CO2 extraction and religious source to one company so they have complete control of everything and that was a little and the been very happy that I've partnered with them in when you talk to the CEO when we have lunch with Gabe the people that are doing the right thing they want help each other out so they're there all about if you want to do CW Charlotte's Web do that CBD line is lying as he lines another one wherever it was like yeah let's just all were not in competition the good the people that are doing the right stuff or not competition with each other there there to educate and that's why want to part with little there were very open about church said yeah we just want to do this and that's why they want to part with me because they know that I want to be publishing lots of clinical data on this yes so at another big thing that Stephen also let me know is that we have to have CBD's that is full spectrum that we had on this a little bit last week and we can get into a little bit about what full spectrum of what the entourage effect is what you learn some words like terpene's final cannabinoids. Full spectrum and then talk a little bit about somebody who may appear reputable doing things like isolates but what limitations are on that so Sean start you what is it mean for something to be a full-spectrum product within your your dispensary yeah and people that have researched using cannabinoids to treat their ailments that that's the first thing that they asked for they want a full spectrum CBD and it it it it is very beneficial because all of these can I have annoyed CBN CBD and CBG and even THC they all work with each other and and that's why having a full spectrum product here extract it is very very beneficial I just I feel like that it's the way that these cannabinoids work with each other to to address your problem so it we had last week we talked about drugs that have been formed down to isolate said actually underperformed compared to what it was they were they were designed to build a home Otilio told me GW pharmaceuticals's, who are hidden@gwpharmaceuticalsaddress.fda approval for PDO lacks direct appeal something like that something like that that I got approved for seizures it is a CDD isolate what is interesting without republishing more there is a great example because I'm not a neurologist but as gas are all just they did try to look at that particular isolate in ulcerative colitis and ended up having a big dropout rate due to side effects I don't see side effects when I use the full spectrum right not all and will and in talking about full-spectrum hit on a little bit also but to you today different cannabinoids as well as another word terpenes so tripping profile can actually mean something and this is this is great for you because we had talked about where is the science going so CVD is new everyone the ECS is not being taught in medical school and that's a brand-new frontier for a lot of people to talk about but how do you know what CBD combinations going to work for you could actually be decent some differentiation in doing that so much going to walk all through this to you Sean so one of the things that I been either the tunnel reading and when you start looking at some of these people who are PhD's in the writing about this it gets pretty high level it's like any other specialty I'm a casserole dish I spent three extra years learning the got just got the version of the Endo Canavan all adjust procedure and looking at all just because the science is getting so dialed in and one of the things it's really interesting is that different combinations may do different things for different people so we talk about the disease state when someone comes in and says shot I got my back I got sciatica can you help me with that that kind of thing so I think that the terpenes are terpenes are in every plant and it it's what you smell not tomato plan has terpenes is an oil it I don't know if it's in oil but it is a component you know in their structure but it does have a smell to it most terpenes do the thing that just blows my mind these guys that manufacture lactate the vape cartridges and this is the easiest way to try to understand terpenes and how they can affect the way or change the way I can have annoyed's informed you that they you can do a full extraction of THC and CBD and you can take a terpene like why mean for instance and add to that extraction you can consume that and have a completely different effect then if you added a blueberry terpene to that extraction was the island versing yes obeyed immersing is one of them that they look that word they have shown that if you have a higher concentration of beta mercy that crosses the blood brain barrier and it brings CBD with it so if you've got a brain issue maybe we need to start using higher immersing levels Piper Ian I think is the other one that's more for joint inflammation like relearning about this is a brand-new science and Sarandon is so exciting and it's gonna take people with the pharmacy background people mean that's why love what you're doing and when you have this educator background is a science and you're bringing all that into this new space that needs to be cleared up that's what we have in the show to talk about the stuff yeah and seizure patients for instance they may take a they may get a perfect dial in profile of medicine that they're taking and it works so let's say I'm having 10 seizures a day and this is working great after about a month or two they may start having one or two seizures a day and then three months later they may have three or four in anger stuff doesn't work or I'm have built up a tolerance to it that's where I call it resetting the cannabinoids clock making little subtle changes with terpenes to the same profile that that works for you the same ratio of CBD and CBN and CBG that works for you in treating your seizures but I need to reset the way that is working with my Indo can have annoyed system if that makes sense so by making a small change with a terpene they have found that it resets that clock and that seizure patient now is medicated and able to go through the day without having one seizure and then after a period of time they reset that clock in and and start over so it that's why it in our medical profession I cannot wait till all of our doctors will sit down with the patient instead of just signing the piece of paper and synonym to the dispensary because the other thing you know were lucky to have Stephen in our dispensary I mean we really are truly blessed I had a patient come in the other day that had gone to a another dispensary that had two ladies that were retired kindergarten teachers that were working at the dispensary in you know they had no idea what was in this model innovate they just knew that it was this process and you know for the same reason the matters we get to CVD are probably matters on his help guide you to listen work for so when I run into whenever I see anybody there's quite a few multilevel marketing companies which are try to get into the CBD industry and what I have seen is that if I go to like a tradeshow or something the have a booth I'll just walk up to me like what's this and listen to what they say and everyone that I've encountered doesn't really understand it and are just throwing the words out and try to do the skills you need this this is the is isolate this is this it's got a full terpene spectrums or will we limit so isolate nursing turbine spectrum dual turbine is no and let my kids laugh because of the accident happened about five times Robbie will tell me more know you wrong that is it just education thing but if you're just trying to move some stuff there ever is using these words like did you heard the term broad-spectrum so broad-spectrum is a marketing term is no such thing as each of the broad-spectrum and I cannot find it fascinating that that's catching on, the Joe dirt style of selling the difference tween blue sky pasta Dragon just does well Doug number one thing that we look for is you now want to know how the medicine was made I want to know where the cannabis came from and I want to know that it was tested and that's why I can't always recommend going and buying this on eBay this on that you stay online for $5.99 in and think it is really going to it it may hurt you your point is now I want to hear your horticultural background how you guys grown up their local well it's funny because you know going into this you know I'm res

Smart Digestion Radio
SDR 52: Remicade

Smart Digestion Radio

Play Episode Listen Later Aug 28, 2018 17:57


Today we’re going to talk about a drug called Remicade. Because I specialize in Crohn’s, colitis, IBS, etc., I see a lot of patients who are either taking this medication, have taken it in the past, or are considering taking it. The problem is: Remicade is among the most toxic of drugs. In this episode, I’m going to share a Facebook Live video I did that breaks down how bad this drug really is. Listen in to hear why Remicade is not only ineffective at healing the body, but how it’s also harming people in dangerous ways. You can find show notes and more information by clicking here: http://thedigestiondoctor.com/52

POLITICO's Pulse Check
Trump's drug plan, explained

POLITICO's Pulse Check

Play Episode Listen Later May 16, 2018 44:22


President Donald Trump finally unveiled his plan to lower drug prices last week, and on this week’s episode, POLITICO looks closer at what’s in the strategy and how it builds (or doesn’t) on the Obama administration’s own efforts. First, POLITICO’s Sarah Karlin-Smith discusses her reporting on the Trump administration’s drug plan (starts at the 2:05 mark), what’s in the bill and how it’s being received. Then after the break, Tim Gronniger — who served as CMS Chief of Staff and led the agency’s work on drug spending under the Obama administration — discusses his impression of the Trump plan (starts at the 14:05 mark), and what he learned from Obama-era efforts to try and lower drug prices, which met with significant resistance and were largely stalled. Stick around for a new segment — “Steal My Job” (starts at the 37:00 mark) — where Tim discusses how he got his jobs in the Obama administration and tips for people interested in a similar career path. GLOSSARY OF TERMS ON THIS EPISODE Average sales price (ASP): A manufacturer's sales of a drug divided by the total number of units, which is used to help set government reimbursement. Biosimilars: A type of product that’s highly similar to existing FDA-approved biologic drugs (like Remicade) but intended to offer a lower-cost alternative. Pharmacy benefit managers (PBMs): A third-party manager of a prescription drug program that helps insurers and others negotiate on drug prices. Drug companies say that PBMs are middlemen that drive up prices. STORIES REFERENCED ON THIS EPISODE Adam Cancryn and David Pittman’s story on the Trump drug plan: https://www.politico.com/story/2018/05/11/trump-administration-drug-price-plan-535667 Sarah’s piece on Trump’s ‘America First’ agenda for drug pricing: https://www.politico.com/story/2018/05/09/trump-drug-pricing-prescriptions-514925

Doctor Doctor
DD #13 - HHS Conscience Protection

Doctor Doctor

Play Episode Listen Later Apr 6, 2018 53:00


In this episode: Medical News (1:50) – Link between nighttime light exposure and depression Preventative Medicine Tip (5:55) – Diabetes Screening Recommendations (https://www.uspreventiveservicestaskforce.org/) Guest Interview (13:50) – Ariana Grossu, Outreach Advisor at the Office for Civil Rights at the US Department of Health & Human Services, discusses the newest HHS initiative – the Conscience and Religious Freedom Division – and what current and potential policies protect health care workers from having to violate their conscience in their practice. For more information visit: www.hhs.gov/conscience Medical Trivia (Answer at 39:15) – According to MedScape.com, which of these prescription medications garnered the most sales in 2016 - at $13.6 billion? 1. Enbrel (etanercept) 2. Harvoni (ledipasvir sofosbuvir) 3. Lantus Solostar (insulin glargine injection) 4. Humira (Adalimunab) 5. Remicade (infliximab) Listener Question (42:30) – If I took birth control when I was younger before I knew about the harmful effects, is there anything I can do now to decrease my risk of getting cancer? Medicine You Need to Know (45:20) – Catholic Witness in Healthcare editor Dr. John Travaline discusses how St. Padre Pio’s vision for authentic Catholic healthcare is coming to the United States ------ Live: www.redeemerradio.com Follow us on Facebook: @DoctorDoctorShow Submit your question(s): Text (Holy Cross College text line) - 260-436-9598 Online - www.RedeemerRadio.com/Doctor E-mail - Doctor@RedeemerRadio.com Subscribe to the Podcast: iTunes | Google Play | SoundCloud | RSS

The SIBO Doctor Podcast
SIBO and Inflammatory Bowel Disease (IBD) with Dr Ilana Gurevich

The SIBO Doctor Podcast

Play Episode Listen Later Jan 30, 2018 52:09


In today's episode Dr Nirala Jacobi is in conversation with Dr Ilana Gurevich on the topic of inflammatory bowel disease (IBD) and small intestinal bacterial overgrowth (SIBO).  Dr Gurevich is a naturopathic physician and acupuncturist who graduated from the National University of Natural Medicine in 2007 and 2008.   She is currently co-owner of two large integrative medical clinics, one in northwest Portland and one in northeast Portland.  Dr Gurevich also runs a very busy private practice specializing in treating inflammatory bowel disease as well as irritable bowel syndrome (IBS), SIBO and functional digestive disorders.      She lectures extensively and teaches about both conventional and natural treatments for inflammatory bowel disease as well as SIBO.  She is one of the foremost experts on the intersection of IBD and IBS and how treating one resolves the other.  Dr. Gurevich also acts as a mentor in the naturopathic community educating about GI disorders.  She supervises residents and consults with physicians about their most difficult GI cases.  Dr. Gurevich was nominated as one of Portland Top Docs by the Portland Monthly in both 2014 and 2016. Topics discussed include: How did Dr Gurevich come to specialise in IBD? How acute flares of IBD can be related to SIBO. In relation to small bowel Crohn's and small bowel Ulcerative Colitis. Testing Dr Gurevich uses for IBD Fecal calprotectin (before getting colonoscopy/gastroscopy) Stool collection to test for leukocytes within the small bowel, giving an accurate sense for how much inflammation is in the intestine. Useful for Crohn's and Colitis. Colonoscopy Gastroscopy Comprehensive digestive stool analysis (CDSA) - Doctor's Data GI Health Panel - DiagnosTechs What kind of flora is in there? Are there parasites, yeast, and assessing food breakdown? ParaWellness Research - parasitologist Dr Jacobi uses Genova GI Effects for the PCR testing and microbiome assessment for anaerobes that could not previously be cultured out. Carroll Food Intolerance Testing Dr Gurevich's view of food allergy testing for IBD patients. Microscopic colitis - what is it? What is its main symptom? Lymphocytic Collagenous Parallels with Coeliac Disease. Clinical pearl - if client is having greater than 10 bowel movements a day look into microscopic colitis and other possible conditions. How to use Budesonide (steroid) for a 3-5 month window, to address microscopic inflammation. Budesonide not as systemic as prednisone, and can be used concurrently to naturopathic care to continue to heal the intestine whilst client tapers off the Budesonide. Does microscopic colitis also show elevated fecal calprotectin? Diagnosing microscopic colitis with colonoscopy or sigmoidoscopy. How is ileocecal valve pressure associated with SIBO? IBD recalcitrant population and why they are more susceptible to SIBO. Bacterial translocation from the large bowel flora into the small bowel and how ileocecal valve scarring increases SIBO susceptibility. How to assess ileocecal valve pressure. Colonoscopy (although not included with a standard colonoscopy). 20% of people are found to have open ileocecal valves. Why? How else is the ileocecal valve scarred? Upcoming workshop in Australia - November 2018 - Dr Steven Sandberg-Lewis on physical exam skills of functional digestive disorders - how to free a stuck open or stuck closed ileocecal valve, the hiatal hernia manoeuvre, and a plethora of other techniques. Lower esophageal sphincter is part of the diaphragm - valvular relaxation treated with Buteyko Breathing. Does Dr Gurevich see much hydrogen sulfide dominant SIBO with IBD patients? Various assessment techniques for the complex hydrogen sulfide dominant SIBO. uBiome Genova GI Effects Flatlining on a SIBO breath test The use of biologic agents in IBD as TNF Alpha inhibitors e.g. Remicade as an IV infusion, Humira as a subcutaneous injection, Cimzia (the only one safe in pregnancy). Biosimilars - generic biologics - about to be launched in the States. Upcoming course with Dr Gurevich for the natural treatment of IBD in 2018 via The SIBO Doctor Education Centre. The body has the potential to treat the biologic agent in the same way as it treats the intestine if the person has IBD - practitioners MUST fully educate the client of the risks of going on or off the biologic agent. What are the increased risks with use of biologic agents? Acute flare treatments that Dr Gurevich uses for Crohn's, Ulcerative Colitis, or both. Rectal ozone - extremely anti-inflammatory and extremely fast acting. Elemental diet - as effective as steroids. Specific carbohydrate diet - SCD Intro included. If no improvement then movement towards steroids to treat acutely. Maintenance treatments that Dr Gurevich uses for Crohn's, Ulcerative Colitis, or both. Carroll test for dietary triggers SIBO test for underlying cause ParaWellness test for underlying cause GI Lumen healing - seacure hydrolysed white fish protein, high dose resveratrol, glutamine, CBD and THC, colostrum, Physica GALT fortifier (Dr Gurevich's new favourite). Always focus on digestive support - enzymes, hydrochloric acid, probiotics (e.g. saccharomyces boulardii for diarrhoea regulation), apple cider vinegar. IV nutrition to help clients who have been ill for a very long time. Do parasites play a role in IBD? Dr Gurevich's experience with butyric acid enemas. Dr Gurevich's position on conventional antibiotics for IBD patients.   Resources Dr Ilana Gurevich Portland, Oregon Kwan Yin Healing Arts Centre Phone consults available Dr Mark Pimentel Mim Beim - Buteyko Breathing Australia Buteyko Clinic International Greg Nigh - Hydrogen Sulfide Expert Dr Jason Hawrelak - Microbiome Expert and Founder of clinical tool - Probiotic Advisor Dr Mona Morstein - Diabetes expert Physica GALT fortifier   Testing discussed Fecal calprotectin Comprehensive digestive stool analysis (CDSA) - Doctor's Data GI Health Panel - DiagnosTechs ParaWellness Research Genova GI Effects Carroll Food Intolerance Testing uBiome   Upcoming courses (2018) November 2018, Australia - Dr Steven Sandberg-Lewis on physical exam skills of functional digestive disorders via the SIBO Doctor Education Centre. 2018, Digital - Dr Gurevich for the natural treatment of IBD via the SIBO Doctor Education Centre.    

CorConsult Rx: Evidence-Based Medicine and Pharmacy
Biosimilars and the Purple Book

CorConsult Rx: Evidence-Based Medicine and Pharmacy

Play Episode Listen Later Dec 23, 2017 2:37


This is a brief discussion of the Remicade biosimilars that have been approved. I also discuss the FDA's Purple Book.

fda biosimilars remicade purple book
Ali on the Run Show
49. Abby Bales, Founder of Reform Physical Therapy

Ali on the Run Show

Play Episode Listen Later Dec 6, 2017 59:34


Abby Bales is the founder of Reform Physical Therapy, which is all about keeping pregnant and postpartum women healthy, active, and injury-free during and after pregnancy. On this episode, Abby explains what exactly that means, why it’s so important — and often overlooked — and what women need to understand about returning to exercise after pregnancy. (Because spoiler, it’s a lot more in depth than just waiting six weeks after birth and then jumping back in.) As someone who isn’t pregnant, has never been pregnant, and has no children, I had loads of questions for Abby, and she was game to answer all of them. She even walked me through the proper way to do kegel exercises! But this episode isn’t just about pelvic floors. Abby and I also talk about her history with Ulcerative Colitis (we’re IBD sisters!), her relationship with running before, during, and after her own pregnancies, and what it’s like being an entrepreneur and mom of two. Stuff We Mention on this Episode: 16 Handles: http://16handles.com/ Crohn’s & Colitis Foundation: http://www.crohnscolitisfoundation.org/ Brian Bosworth: http://nyulangone.org/doctors/1881643849/brian-p-bosworth Canasa: http://www.canasa.com/ Remicade: https://www.remicade.com/ Kara Goucher: http://www.aliontherunblog.com/2017/10/25/ali-run-show-episode-43-kara-goucher/ TCS New York City Marathon: https://www.tcsnycmarathon.org/ Hamptons Marathon: http://www.aliontherunblog.com/2011/09/25/i-am-a-marathoner-the-official-hamptons-marathon-recap/ Bank of America Chicago Marathon: https://www.chicagomarathon.com/ Elvie: https://www.elvie.com/ Goop: https://goop.com/ Hillstone: http://hillstonerestaurant.com/ River to Sea Relay: https://www.r2crelay.com/ Follow Abby & Reform Physical Therapy: Instagram @reformptnyc: https://www.instagram.com/reformptnyc/ Facebook: https://www.facebook.com/reformptnyc/ Twitter @reformptnyc: https://twitter.com/ReformPTNYC Website: https://reformptnyc.com Email: abby@reformptnyc.com Follow Ali: Instagram @aliontherun1: https://www.instagram.com/aliontherun1 Facebook: https://www.facebook.com/aliontherun/ Twitter @aliontherun1: https://twitter.com/aliontherun1 Blog: http://www.aliontherunblog.com/ Strava: https://www.strava.com/athletes/13333410 Thank you for listening to and supporting the Ali on the Run Show! If you’re enjoying the show, please subscribe and leave a rating and review on iTunes. Spread the run love!

Dr. and Mrs. Guinea Pig with Heather and Terry Dubrow
Heather & Terry Answer Your Questions!

Dr. and Mrs. Guinea Pig with Heather and Terry Dubrow

Play Episode Listen Later Oct 30, 2017 61:14


As they talk about male plastic surgery options, Heather & Terry answer your questions about Kybella, maintaining perky breasts, and getting plastic surgery with Remicade.

Child Life On Call: Parents of children with an illness or medical condition share their stories with a child life specialist

At just six years old, Susan's son began complaining of belly pain along with other alarming symptoms. After a trip to the doctor, they were quickly sent to meet with a Pediatric Gastroenterologist and would eventually learn the news that one of her sons, Preston, had Crohn's disease. Susan shares personal details about their journey, procedures, and treatments that are associated with Preston's experience with Crohn's. She discusses how she and her family cope with living with this disease. Susan is honest, articulate and gives priceless advice to parents who may be going through similar situations.   Susan says that reaching out to her own doctor and support system was invaluable in helping her cope with a child who has an illness. She and her husband face each challenge with trusting fully in her sons health care team, leaning on each other, and prayer.    If you would like to connect with Susan, you can follow along with her on Instagram or Facebook. She recommends the Crohn's section on kidshealth.org and researching your child's specific medication in order to feel empowered.    If you would like to share your story, you can message Child Life On Call's Twitter, Facebook or Instagram or submit your information on childlifepodcast.com or email info@childlifepodcast.com  

Evolution Radio Show - Alles was du über Keto, Low Carb und Paleo wissen musst
Colitis Ulcerosa - Hilfe durch das Autoimmun Paleo Protokoll

Evolution Radio Show - Alles was du über Keto, Low Carb und Paleo wissen musst

Play Episode Listen Later Jul 11, 2017 46:28


In Folge #117 Das Video der aktuellen Folge direkt auf Youtube öffnen Bitte beachten Sie auch immer den aktuellen "Haftungsausschluss (Disclaimer) und allgemeiner Hinweis zu medizinischen Themen" auf https://paleolowcarb.de/haftungsausschluss/ #geNUSS[explosion] von [næhr:sinn] - das low carb knusper nuss müsli [næhr:sinn] geNUSS[explosion] ist ein hochwertiges low-carb* Müsli und besteht zu 100% aus natürlichen Zutaten. Es ist gut als Frühstück und Snack und hat nur 13,7g verwertbaren Kohlenhydraten auf 100g. Es ist getreidefrei und sojafrei. Perfekt für den Start in den Tag. Wir verarbeiten nur hochwertigste, nährstoffreiche Zutaten, die dich länger satt machen und nachhaltig mit Energie versorgen. Wir nutzen ballaststoffreiche Kokosnuss, Erdmandel und heimische Nüsse. Mehr darüber erfährst du auf lowcarbmüsli.at oder auf Amazon.de Und nicht vergessen: Wenn du uns auf Youtube siehst, und wenn du es noch nicht getan hast, dann abonniere unseren Kanal „Evolution Radio Show“ Wenn du das Podcast hörst, dann findest du die Links für Apple iTunes und Android hier auf unserer Homepage Kurze Zusammenfassung Heidrun Schaller ist 25 Jahre alt und gerade dabei ihren Master in Linguistik abzuschließen, als sich ihr Leben, durch eine dramatische Diagnose vollkommen verändert - Colitis ulcerosa, und zwar eine besonders schwere Form der chronisch entzündlichen Darmerkrankungen. Bei den chronisch entzündlichen Darmerkrankungen (CED) entzündet sich der Darm aus unerfindlichem Grund und bleibt dann mal mehr, mal weniger entzündet. Weil man eben den Grund nicht kennt, ordnet man die Krankheiten pauschal den Autoimmunkrankheiten zu. Die Symptome sind extremer Durchfall (in akuten Phasen ggf. über 20mal pro Tag), Gewichtsverlust, Blutverlust, Bauchschmerzen, Übelkeit, Nährstoffmangel etc. Viele Patienten müssen irgendwann operiert werden, um Teile des Darms zu entfernen, manche auch viele Male, manche leben irgendwann mit einem künstlichen Darmausgang. Die Diagnose ist ein Lebensurteil – man wird zu einem Leben mit der Krankheit verurteilt, denn Aussicht auf Heilung gibt es nicht. Wäre die Krankheit an sich nicht schon schlimm genug, treten bei Heidrun noch andere seltenere Probleme auf. Das Standartmedikament Mesalazin (5-ASA, Markenname Pentasa, Salofalk oder Claversal), schädigt Heidruns Nieren massiv. Das andere Medikament, Azathioprin schied wegen eine Unverträglichkeitsreaktion aus. Als letzten Strohhalm versuchte Heidrun die Therapie mit einem Immunsuppressivum (Remicade). Sie erlitt einen anaphylaktischen Schock und kam in die Notaufnahme. Somit gab es für sie –abgesehen von Kortison – eigentlich keine medizinische Behandlungsoption mehr. Verzweifelt und auf der Suche nach Alternativen, stolpert Heidrun über die Specific Carbohydrate Diet (SCD) und beginnt diese dann ab August 2011 umzusetzen, mit überraschenden Ergebnissen. Gleichzeitig wird Heidrun auch auf Paleo aufmerksam und da die SCD und Paleo sehr viele Überschneidungen haben, probiert sie den Übergang von SCD zu einem Autoimmun-Paleo Protokoll (AIP). Heidrun Schaller lebt seit dieser Zeit strikt nach AIP. Durch Selbstversuche und Testen neuer Konzepte hat sie für sich die SCD und AIP optimiert. In ihrem Blog www.urgesundheit.de und in ihrem Buch Die Paleo-Revolution: Gesund durch Ernährung im Einklang mit unserem genetischen Erbe - Heidrun Schaller hat sie ihre Erfahrungen zusammengefasst. [] #Transkript Julia: Liebe Heidrun, herzlich willkommen zur Evolution Radio Show. #00:00:10-3# Heidrun: Dankeschön für die Einladung. Ich freue mich hier zu sein. #00:00:13-5# Julia: Ich freue mich ganz besonders, dass ich dich endlich mal erwischt habe, weil du bist sehr, sehr eingeteilt natürlich. In welcher Weise, da wirst du noch jetzt ein bisschen dann später drauf zu sprechen kommen. Weil du bist nicht nur eine Mutter, sondern hast dir auch ein großes Ziel gesetzt. Bevor wir jetzt über das eigentliche Thema, nämliche die Autoimmunerkrankung sprechen, vielleicht kannst du mal ein paar Worte zu deinem Hintergrund sagen und dann gerne überleiten zu deiner Geschichte, die dich in den letzten Jahren praktisch geprägt hat und dahin gebracht hat oder auf den Weg gebracht hat, wo du jetzt bist. #00:01:03-6# Heidrun: Ja, sehr gerne. Ich bin eigentlich von Haus aus Übersetzerin. Ich habe 2001 mein Diplom gemacht an der Uni Heidelberg. Geboren und aufgewachsen bin ich in München und war halt während meiner Studienzeit und auch davor viel in Amerika unterwegs. Also gleich nach dem Abitur war ich erstmal ein Jahr als Au Pair in Seattle und auch während meiner Studienzeit hatte ich dann nochmal ein Stipendium in einem College in Amerika und war halt immer sehr viel unterwegs und dann als ich so gegen Ende meiner, also eigentlich nach dem Vordiplom in Australien gelebt habe mal für ein halbes Jahr, da habe ich gemerkt, dass mit meiner Gesundheit irgendwas nicht stimmt. Da habe ich schon oft Bauchschmerzen gehabt und gerade, wenn ich irgendwie in Eile war oder so, habe ich häufig Durchfallattacken bekommen und das habe ich halt auf mein hektisches Leben zurückgeführt und mir da nicht weiter Gedanken drübergemacht. Und dann, als ich dann wieder in Heidelberg war und mein Studium dort wieder aufgenommen habe, also mein Hauptstudium dann in Richtung Übersetzerdiplom, da wurde es aber immer schlimmer und ist dann auch nicht mehr weggegangen, selbst in ruhigeren Zeiten und irgendwann kam ich dann nicht mehr drum rum, dass ich mich dieser Sache mal stellen musste und habe dann eben 2001, also genau in der Prüfungsphase, als ich mich gerade eigentlich auf die mündliche Prüfung vorbereitet habe, habe ich dann die Diagnose bekommen, dass ich Colitis ulcerosa habe und das war natürlich ein wirklich sehr, sehr großer Schock, weil ich zwar schon damit gerechnet habe, dass ich irgendwie krank bin, aber natürlich in keinster Weise irgendwie darauf mental vorbereitet war, dass es jetzt was ist, womit ich mich den Rest meines Lebens herumschlagen muss. Das war eben dann schlussendlich die Feststellung, dass es tatsächlich unheilbar und chronisch ist und dass es eben nur Medikamente gibt, die möglichst unter Kontrolle halten sollen, aber niemals eine Heilung herbeiführen können. #00:03:17-9# Julia: Für die Zuhörer und Zuschauer, könntest du mal noch erklären: Was ist Colitis ulcerosa eigentlich? #00:03:23-9# Heidrun: Das ist eine chronische Autoimmunerkrankung, die den Verdauungstrakt betrifft, ähnlich wie Morbus Crohn, welche vielleicht ein bisschen bekannter ist. Im Gegensatz zu Morbus Crohn ist eben bei der Colitis ulcerosa "nur" der Dickdarm betroffen und bei Morbus Crohn kann der Magen, auch der Dünndarm eigentlich alles, sogar die Speiseröhre betroffen sein. Dann entzündet sich eben die Schleimhaut jeweils in dem betroffenen Abschnitt des Verdauungstraktes, in dem Fall eben im Dickdarm und das führt eben dazu, dass man sehr, sehr häufig Durchfälle hat, teilweise auch blutige Durchfälle oder mit Schleimabgang. Teilweise 20 bis 30 Mal am Tag, sodass man das Haus nicht mehr verlassen kann. (Julia: Wahnsinn) Man nimmt teilweise sehr, sehr stark innerhalb kürzester Zeit ab. Das war also auch bei mir der Fall, dass ich halt sehr, sehr dünn geworden bin und wenn das unbehandelt ist, kann es einen halt umbringen, ansonsten, wenn es, also selbst für Leute, die das relativ gut unter Kontrolle halten, kommt es über die Jahre dann häufig noch zu anderen Erscheinungen, dass zum Beispiel die Gelenke mit betroffen sind. Also, dass man dann so Art rheumatische, ja es heißt immer extraintestinale Manifestation, also außerhalb des Verdauungstraktes kommt es dann auch zu Symptomen. Julia: Es ist ja auch oft so, dass oder bei vielen, dass eine Autoimmunerkrankung oft nicht alleine kommt. #00:05:03-4# Heidrun: Das kommt noch hinzu. Ja. #00:05:04-4# Julia: Dass ja dann oft auch andere Autoimmunerkrankungen dazukommen. #00:05:09-9# Heidrun: Richtig. Ja. Genau. Also bei Colitis ulcerosa und Morbus Crohn ist es häufig so, dass die dann, dass Hashimoto relativ verbreitet ist als zusätzliche Erkrankung, aber auch sehr häufig Rheuma. Und so ging das halt dann, also so ging es dann mit mir bergab, sage ich mal salopp. Ich habe halt, also da stellte sich dann leider sehr bald mal raus, dass meine Erkrankung sehr kompliziert war, also kein leicht zu behandelnder Fall. Ich habe halt sehr viel Komplikationen erlitten und auch die Medikamente, die zur Verfügung standen, die waren bei mir nicht sehr effektiv. Und dass ich halt immer hohe Dosen nehmen musste. Und zu Anfang war es ja so, dass ich natürlich gleich mit Cortison behandelt wurde. Das ist ja so das Standardmedikament, was die Schübe also eindämmen soll und wenn es gut läuft, dann muss man das halt nur kurze Zeit nehmen und kann dann, wenn man die Remission, also die symptomfreie oder fast symptomfreie Phase erreicht hat, dann ohne Cortison leben, aber bei mir kam es halt nicht dazu, weil ich gleich immer wieder Rückfälle hatte. Wenn ich eine gewisse Schwelle unterschritten habe von diesem Cortison und da hatte ich halt sehr schlimmer Nebenwirkungen davon. Also ein bisschen ist das ja bekannt von Cortison, dass man halt eine starke Gewichtszunahme erleidet. Das war jetzt bei mir gar nicht so schlimm, aber ich halte ein unglaublich verändertes Aussehen vom Gesicht her. Es war sehr, sehr rund, ich weiß nicht, ich kann ja das Foto mal zeigen, was ich in meinem Buch davon habe. Ich weiß nicht, ob man es sehr gut erkennen kann auf der Kamera. Ich zeig es mal. #00:06:49-0# Julia: Sonst könnten wir, ja du kannst es mal herzeigen, weil sonst würden wir es, wenn es dir recht ist, können wir es dann auch in den Shownotes noch dazu geben? Ah ja. Vollkommen anders. Man sieht es sehr gut. Ja. #00:07:02-0# Heidrun: Das war natürlich auch belastend irgendwo und man wusste halt einfach, also man wusste halt einfach nicht, wann man das Zeug mal wieder loswird. Dann einfach so auch psychisch unheimlich belastend gewesen, also es hat mich ja mitten in meinem Diplom halt, in der Diplomvorbereitung hat mich das getroffen wie der Schlag und ich wusste nicht, ob ich jemals irgendwie ein annähernd normales Berufsleben oder auch sonstiges Leben hätte führen können. #00:07:31-1# Julia: Was muss man sich das vorstellen? Wie ist da normalerweise die Progression? Weil es ist ja nicht heilbar eigentlich. Also wie wir das normalerweise behandelt beziehungsweise wie schaut das normalerweise aus? #00:07:47-9# Heidrun: Wie gesagt, die akuten Schübe, die werden eigentlich fast immer mit Cortison behandelt erstmal, sozusagen als Notfallprogramm erstmal, um die Entzündung runterzufahren. Und dann ist halt das Standardmedikament, was man eigentlich durchgängig nimmt, auch während dem Schub, aber eben auch während der Remission, das ist dieses sogenannte Mesalazin, und das ist halt ein Verwandter sage ich mal von Aspirin, von Acetylalicylsäure. Aber es ist, also wurde mal gesagt, dass es so gut wie nebenwirkungsfrei ist, aber in meinem Fall war das halt leider nicht so. Ich habe dann nach zweieinhalb oder drei Jahren, wo ich das genommen habe, eine Nebenwirkung gehabt, die sehr selten ist. Und zwar war es bei mir so, dass meine Nierenfunktion mit einem Mal eingeschränkt war. Und das wurde dann halt immer wieder untersucht und es stellte ich, also kam halt raus, dass das jetzt tatsächlich der Fall ist und nicht nur einmal irgendwie ein zufälliger Untersuchungswert war und dann stellte sich eben raus bei genauerer Betrachtung, dass ich nur noch 30 Prozent Nierenfunktion hatte. Das ist also so, als ob man weniger als eine Niere noch hat, deutlich weniger. Denn eine Niere kann eigentlich 100 Prozent sogar bringen. Das heißt, ich hatte im Prinzip keine Niere mehr. Und die Niere kann sich ja nicht regenerieren, also das ist nicht wie die Leber, die dann irgendwann wieder gesunden kann, sondern wenn die Nierenfunktion weg ist, dann ist die halt weg. Das war dann auch wieder so ein Fall, wo ich halt sehr für mich selbst dann sprechen musste und aktiv werden musste, weil mein Arzt damals eben nicht der Meinung war, dass das Mesalazin dafür verantwortlich ist. Aber ich habe halt mich wirklich schlaugemacht und recherchiert, war wirklich der Überzeugung, dass das davon kommen muss. Und es stellte sich dann eben auch raus, dass ich Recht hatte und zum Glück konnte ich noch die Notbremse ziehen, weil der hätte mir das halt immer weiter verschrieben. Habe dann auch später den Arzt gewechselt natürlich. Aber es war natürlich blöd, weil das Mesalazin ist relativ wichtig auch in der Behandlung und dadurch, dass das weggefallen ist, war ich dann halt wieder dem erhöhten Risiko eines Schubs ausgesetzt ständig. #00:10:03-6# Julia: Und da bleibt dann nur mehr Cortison übrig? #00:10:07-8# Heidrun: Ja, also eigentlich, es gibt natürlich noch andere Medikamente, die natürlich weit weniger gerne verschrieben werden. Das sind dann diese Immunsuppressiva, wie zum Beispiel Azathioprin und Methotrexat. Aber Methotrexat konnte ich nun ironischerweise gerade nicht mehr nehmen, weil das darf man bei eingeschränkter Nierenfunktion eben nicht nehmen. #00:10:26-2# Julia: Okay. #00:10:26-3# Heidrun: Auch weg. Dann habe ich Azathioprin verschrieben bekommen, das ist eben ein Immunsuppressivum und das hat bei mir auch eine seltene Nebenwirkung hervorgerufen, nämlich eine sogenannte Knochenmarkdepression. Da habe ich ein ganz verändertes Blutbild dann gehabt. Ich glaube, das war eine Thrompozytopenie, also ich hatte weniger Blutplättchen, und hatte auch, ich sah wirklich aus, als wäre ich vermöbelt worden. Ich hatte wirklich am ganzen Körper blaue Flecken. Das haben wir dann zweimal versucht mein Arzt und ich, also eingeschlichen, ausgeschlichen, wieder eingeschlichen und es kam halt beide Male zu diesem Effekt. Und dann haben wir das auch wieder aufgegeben und dann habe ich, weil mein Arzt nun auch schon ziemlich ratlos war, hat er mir empfohlen Ausdauersport anzufangen. Das war seiner Meinung nach irgendwie so, also er war da auch so ein bisschen auf so einem Trip, das war so sein Steckenpferd irgendwie. Und das habe ich dann halt wirklich sehr, sehr obsessiv gemacht. Ich bin wirklich sechs Mal die Woche halt joggen gegangen, ausdauersport-mäßig und das hat, also hat mir glaube ich nicht geschadet, aber es war halt einfach ein extremer Stressfaktor, weil das muss man auch erstmal in seinen Alltag einbauen. (Julia: Auf jeden Fall) So viel Sport zu machen und es war halt wirklich so, dass teilweise im Sommer kam ich halt nicht mehr dazu irgendwie an den See zu fahren oder so, weil nach der Arbeit war halt dann Sport angesagt. Das, was andere Leute so in ihrer Freizeit machen, da konnte ich halt nicht dran teilnehmen und deswegen habe ich es dann auch irgendwann nicht mehr durchgehalten. Und dann, womit habe ich dann eigentlich weitergemacht? Ach ja, genau. Dann hatte ich ja irgendwann zu einem anderen Arzt gewechselt und der hat dann versucht mir Remicade, das ist Inflixamab heißt das, das ist ein sogenannter monoclonaler Antikörper. Also das sind diese Biologika, die man eben so aus der Rheumabehandlung auch kennt. Das ist auch so eine Art Immunsuppressivum und eigentlich schon sehr fortschrittlich und sehr gezielt und das hat aber bei mir sofort einen anaphylaktischen Schock hervorgerufen. Also ich bin in der Praxis sozusagen mit Tatütata ins nächste Krankenhaus eingeliefert worden, weil ich halt wirklich dort, kaum dass die ersten Tropfen liefen, hat mich sofort, habe ich keine Luft bekommen, hatte hier Flecken überall und es war damals klar, dass ich das auch nicht nehmen kann. Das war halt wirklich so der letzte Strohhalm. Denn das war wirklich, also das ist ja schon keine leichte Entscheidung so ein Medikament überhaupt anzunehmen, denn es geht auch mit einem Risiko einher. Also Remicade und auch die anderen Biologika haben alle immerhin schon ein signifikantes Krebsrisiko. Und dass das halt nicht funktioniert hat, das war dann schon auch ein herber Schlag. Und habe ich dann eben angefangen vermehrt nochmal wieder im Internet zu recherchieren, habe ich schon immer gemacht, ich habe ja auch immer nebenbei 1.000 Sachen probiert, die halt, es wird ja dann immer irgendeine Sau durchs Dorf getrieben in der Szene. Julia: So nur von der Orientierung her, welches Jahr sind wir da circa? #00:13:44-2# Heidrun: Moment, jetzt haben 2017, das muss dann so 2011 gewesen sein. #00:13:48-8# Julia: Okay. #00:13:49-6# Heidrun: Ja. Genau. Und da bin ich dann nochmal, ach ne warte mal, das war sogar, ne warte mal, ich habe ja nicht sofort mit der Ernährungsumstellung angefangen. Ich habe, das war dann doch eher so 2008. #00:14:06-7# Julia: Okay, doch. Ja. #00:14:07-6# Heidrun: Da habe ich mich dann nochmal im Internet so in verschiedenen Foren angemeldet und so. Und dann hat es noch ein Stück gedauert bis ich irgendwann über Facebook eben dann auf diese STD-Ernährung gestoßen bin, Specific Carbohydrate Diet. Das war zunächst mal mein Ding und das war also wirklich, das hat mich so sehr geprägt oder war halt wirklich eine coole Sache, war ein wahnsinnig guter Einstieg in die Ernährungsumstellung. Da ist die Specific Carbohydrate Diet eben eine Diät, eine Ernährungsweise, die wirklich von Leute mit meiner Erkrankung mal erdacht worden ist. Ursprünglich von einem Kinderarzt in Amerika, dem Doktor Haas und dann später von einer Frau Gottschall weitergeführt. Die hat eben auch ein Buch darüber geschrieben, das heißt einfach Specific Carbohydrate Diet oder Breaking the Vicious Cycle. Also das heißt ja, den Teufelskreis durchbrechen und das war halt, da habe ich wirklich auch lange gebraucht, bis ich bis mich dazu durchringen konnte das zu probieren, weil ich halt schon so viele alternative Methoden ausprobiert hatte und alles hat nur Geld gekostet und hat dann am Ende nicht gebracht. Aber irgendwann habe ich den Sprung ins kalte Wasser dann gewagt und der Unterschied zwischen der Specific Carbohydrate Diet und der Paleo-Ernährung ist jetzt erstmal, dass bei der SCD sage ich jetzt mal, das ist ja die Abkürzung dafür, (Julia: Genau) dass dort alle Stärke komplett verboten ist, man darf überhaupt keine Stärke zu sich nehmen, auch keine Süßkartoffeln, auch keine Kochbananen, nichts. Der Hintergrund ist halt, dass der Herr Dr. Haas die Theorie hatte, dass insbesondere im Dünndarm die Enzyme fehlen bei Leuten mit chronisch entzündlicher Darmerkrankung, um Stärke aufzuspalten. Eben diese Polysaccharide dann als solche bestehen bleiben und den falschen Bakterien oder Bakterien, die uns nicht guttun, als Futter dienen. Und dann eben, weil sich dann die Schleimhaut, also nicht Bakterien, sondern die Immunzellen, die sich in der Schleimhaut befinden, wehren sich irgendwann gegen diese enorme Vermehrung von Bakterien und dadurch kommt das eben zu Entzündungsprozessen oder sie werden angeheizt, wenn sie schon bestehen. Also das hat mich unheimlich begeistert natürlich, dass das wirklich schnell angeschlagen hat. Das war tatsächlich wirksam, das konnte man deutlich erkennen und auch nicht leugnen. Selbst mein Arzt war beeindruckt. Das ist ja schon mal sehr selten, dass man ... #00:17:00-6# Julia: Also du hast umgestellt und hast dann sehr schnell positive Ergebnisse, Veränderungen gesehen? #00:17:06-1# Heidrun: Richtig. Ja. Ich habe sogar, ich glaube so 1 Monat oder 6 Wochen nachdem ich damit angefangen hatte, hatte ich eine Darmspiegelung und da habe ich halt wirklich zum ersten Mal seit meiner Diagnose keine Entzündungszeichen gehabt. (Julia: Wahnsinn) Also mein Arzt und der ist normalerweise oder überhaupt sind Schulmediziner ja normalerweise nicht unbedingt so angetan davon, wenn man ihnen von irgendwelchen Wundermittelchen oder Lebensstilveränderungen berichtet oder halt von den Erfolgen, die man damit hat. Und der hat aber dann auch daran also schon war dann meiner Meinung auch und hat sich meiner Auffassung angeschlossen, dass das wirkt und dass ich weitermachen soll. (Julia: Super) Und dann also natürlich die Gemeinsamkeiten der SCD mit der Paleo-Ernährung sind weitaus größer als die Unterschiede, also es geht halt auch da drum, (unv.) Essen selber zu machen, hochwertige Produkte zu verwenden, keine industriell vorgefertigten, also keine Fertigprodukte oder ähnliches zu verwenden und man isst auch zuckerfrei, aber nur in dem Sinne, dass man halt keine so Succrose isst, also Honig zum Beispiel darf man essen und auch Obst und also alles, was Fructose und Glukose enthält darf man essen, weil es eben darum geht, dass es Monosaccharide sind, man darf nur Monosaccharide zu sich nehmen, weil alles, was stärker polymerisiert ist sozusagen, vom Körper dann nicht gespalten werden kann. #00:18:39-2# Julia: Ja. Gut. Und bei den Monosacchariden da braucht man natürlich nichts mehr spalten. #00:18:43-4# Heidrun: Genau. #00:18:44-6# Julia: Das geht so. Und ich die SCD auch eher Lower-Carb, (Heidrun: Genau) also wird grundsätzlich schon kohlenhydratreduziert kann man sagen oder? #00:18:57-8# Heidrun: Ja also dadurch, dass man ja Obst jetzt nicht in unbegrenzten Mengen zu sich nimmt und also ich bin jetzt auch nicht so der Mensch, der irgendwie haufenweise Honig in den Tee rührt oder so. Also ich habe sehr, sehr low carb gegessen, weil halt der größte Anteil von dem, was ich so an Kohlenhydraten früher zu mir genommen habe, war halt schon in Form von Stärke und dadurch, dass das weggefallen ist, hatte ich dann automatisch eine sehr low carb Ernährung. Also das war halt dann letztendlich auch der Punkt, der mir dann irgendwann zu schaffen gemacht hat, weil ich halt, obwohl ich schon sehr dünn war, als ich angefangen habe damit, bin ich halt immer dünner geworden und in den Foren, wo ich dann davon berichtet habe oder wo auch andere eben mit diesem Problemen zu kämpfen hatten, da kam immer der Ratschlag von den alten SCD-Hasen, ja mach weiter, mach weiter, weil nach 3, 4 Monaten hört das auf oder manche haben auch gesagt nach 6 bis 9 Monaten kehrt sich der Trend von selber um und du wirst dann wieder zunehmen, weil dein Darm ausgeheilt ist, wirst du dann wieder zunehmen. Aber dieser Punkt kam halt bei mir einfach nicht, sondern ich wurde immer dünner. Also das war halt nicht gut und deswegen habe ich dann irgendwann, ich hatte natürlich dadurch, dass es ja so starke Überschneidungen gibt zwischen der Paleo- und der SCD-Stile, hatte ich auch eigentlich fast zeitgleich mit der SCD auch von Paleo gehört und habe mich dann da vermehrt eingelesen und bin dann irgendwann zu der Überzeugung gelangt, das will das mal ausprobieren sollte, einfach weil man dort auch Stärke zu sich nehmen kann und das habe ich dann halt gemacht. Da konnte ich dann auch mein Gewicht zumindest stabilisieren und auch wieder zunehmen. Ich muss aber sagen, dass es, also immer, wenn ich doch mal wieder Zeiten habe, wo ich mehr Beschwerden spüre, da ist es doch dann gut, wenn ich 1, 2 Tage wirklich gar keine Stärke ... #00:20:52-3# Julia: Okay. Ja. #00:20:53-4# Heidrun: Also das ist macht auf jeden Fall einen Unterschied aus. #00:20:56-9# Julia: Und wie, weil es mich halt persönlich auch interessiert, wie geht's dir da mit Fett, also kannst du das gut aufnehmen oder musst du da auch aufpassen oder? #00:21:06-9# Heidrun: Also, wenn ich gerade Symptome habe, dann komme ich mit Fett nicht so gut klar. Das ist halt ein bisschen blöd, weil man hat immer so diesen, man muss immer abwägen, man muss immer einen Kompromiss finden zwischen den Kalorien, die man ja braucht, gerade wenn man nicht noch weiter abnehmen möchte und dann ist es aber hier eben mit dieser Darmerkrankung auch schwierig, weil gerade die Dinge, die halt auch satt machen, nämlich Kohlenhydrate und Fette sind beides jetzt Dinge, die nicht so einwandfrei verträglich sind. #00:21:38-7# Julia: Okay. Ja. Eben. So ist es. Ja. #00:21:41-9# Heidrun: Mit Proteinen kommt man eigentlich am besten klar, mit magerem Fleisch. Das ist ... #00:21:46-2# Julia: Okay. Aber da ist halt auch begrenzt wieviel man Fleisch oder mageres Protein mal zu sich nehmen kann, ist dann natürlich sehr schwierig, weil man von der Fettseite her auch eingeschränkt ist. #00:21:57-5# Heidrun: Ja. Das stimmt. Also die Elaine Gottschall, die ja dieses Buch geschrieben hat, auf das eigentlich die SCD heute sich hauptsächlich stützt, die hat auch gesagt, dass man in der ersten Zeit, also es gibt so eine Intro Diet, die man halt 2, 3 bis 4 Tage machen soll, wenn man damit anfängt, und da spielt die selbstgemachte Hühnersuppe eine wichtige Rolle und da sagt sie halt auch, dass man während der Intro Diet das Fett abschürfen sollte. Also das ist auch wirklich ein sinnvoller ... #00:22:30-4# Julia: Okay. Das heißt, von deiner Erfahrung her, dass wenn jetzt jemand beginnen möchte, auch mit der Ernährungsumstellung, wirklich zuerst mal auf jeden Fall nach der SCD das umsetzen und dann vielleicht eine Transition zu einer Paleo-Ernährung? #00:22:53-0# Heidrun: Ja. Das ist schwierig. Das weiß ich gar nicht so genau, was ich da raten würde ehrlichgesagt. Also ich persönlich habe eigentlich mit der AIP angepasst, mit Paleo-Ernährung wahrscheinlich eher die größeren Erfolge gehabt. Es war nämlich so, ich habe ja, also bei Elaine Gottschall ist es halt so, dass die eher stark den Fokus auch auf Nusslinie und so weiter richtet. Also bei ihr wird ja sehr viel gebacken. Also in dem Rezeptteil des Buches wird sehr, um dann diese Ernährung irgendwie halbwegs erschwinglich zu machen und auch für eine gewisse Sättigung zu sorgen, schlägt sie halt vor, dass man auch wirklich Brot bäckt aus Nussmehl und so weiter und das hat halt bei mir nicht wirklich funktioniert, weil ich dann mit der Zeit auch so eine, am Anfang ging es irgendwie noch, aber mit der Zeit wurde ich irgendwie immer empfindlicher gegen die Nussmehle. Konnte ich dann irgendwann gar nicht mehr gut vertragen und dadurch wurde es dann immer schwieriger. Da hat mir das dann auch wirklich gefehlt, dass ich irgendwie halt die Stärke, die hat mir dann noch mehr gefehlt als davor. Und da war ich halt dann froh, dass ich, also ich die AIP, also das Autoimmunprotokoll der Paleo-Ernährung entdeckt habe, das damit ergänzen konnte und einfach leichter, unkomplizierter und billiger satt geworden bin. #00:24:14-6# Julia: Was sind denn die großen Unterschiede jetzt zwischen Normal-Paleo und dem Autoimmunprotokoll der Paleo-Ernährung? #00:24:23-3# Heidrun: Also beim Autoimmunprotokoll da fallen die Nachtschattengewächse weg, also sowas wie Kartoffeln und Tomaten und Auberginen und so weiter, dann natürlich Nüsse und Mandeln. Was fehlt den noch? #00:24:43-9# Julia: Wie schaut es mit Eiern aus? #00:24:45-6# Heidrun: Ach ja genau. Eier und Milch fallen auch weg. Ja. #00:24:49-7# Julia: Also das stelle ich mir persönlich ja sehr schwer ... #00:24:51-8# Heidrun: Das ist mir deswegen jetzt auch nicht eingefallen, weil ich die nicht befolgt habe. Weil das habe ich nämlich, also ich habe halt so ein bisschen auch selber ausgetestet, was mir guttut und was nicht und habe halt gemerkt, dass Eier und Milch für mich, also Laktose habe ich schon nicht zu mir genommen, weil da habe ich mich wieder so ein bisschen an der SCD orientiert, weil Laktose ist ja wieder ein Zweifachzucker, also ein Disaccharid, und das kann man ja dann wieder nicht spalten und das habe ich auch für mich so empfunden, dass Laktose eben eher nicht so gut geht und deswegen habe ich nach dem SCD-Protokoll für mich selber Joghurt zubereitet, der 24 Stunden fermentiert und der ist ja 24 Stunden ist er laktosefrei. Dafür habe ich dann auch teilweise Rohmilch verwendet und das war super. Also ist mir immer super gut bekommen, hat auch sattgemacht und war halt lecker auch einfach und bei anderen Milchprodukten, also Milch so, also einfach Milch im Rohzustand oder in flüssiger Form habe ich halt nicht zu mir genommen, aber ich habe immer Butter gegessen, ich habe immer Brie gegessen und habe immer gereiften Käse auch dann zu mir, also jetzt keinen Frischkäse oder Quark oder so, aber halt den gereiften, der dann auch laktosefrei, den habe ich auch gegessen. #00:26:10-1# Julia: Hast du da irgendwie einen Unterschied zwischen Kuhmilch oder Ziege und Schaf oder so gemerkt oder ist das ...? #00:26:16-2# Heidrun: Ich persönlich habe das nicht gemerkt. Nein. Ich habe es immer mal ausprobiert, gerade wenn ich wieder nicht so gut klargekommen bin, dann habe ich versucht irgendwie da auszuweichen auf Ziegenmilch oder so oder Ziegenkäse, aber das hat eigentlich für mich keinen Unterschied gemacht. #00:26:30-2# Julia: Keine Auswirkungen. Für dich ist eigentlich also wichtig gewesen, dass die Laktose weg ist oder reduziert auf jeden Fall und hast du dann auch, weil du gesagt hast, dass du Rohmilch verwendest, um das Joghurt zu mache, hast du da Erfahrungen, das konventionelle oder normales Joghurt aus dem Geschäft dir weniger guttut oder war das einfach eine andere Motivation? Heidrun: Nein, das war eigentlich mehr eine theoretische Überlegung. Ich habe die Rohmilch übrigens dann abgekocht, was natürlich dann keine Rohmilch mehr war, die ich letztendlich eingesetzt habe, aber ich fand es halt unheimlich schwierig heutzutage Milch zu finden, die Bio ist, aber gleichzeitig nicht diese sogenannte länger haltbare Milch ist. Das steht dann zwar drauf auf den Packungen, aber das bedeutet ja nichts Anderes als, dass die eigentlich homogenisiert ist. Und das wollte ich halt vermeiden, weil da ja eben verschiedentlich dann auch zu lesen ist, dass diese sehr fein verteilten Fetttröpfchen, die ja dann ganz klein sind, dass die teilweise dem Verdauungstrakt auch Probleme bereiten können. (Julia: Genau. Ja.) Deswegen, das wollte ich halt, ich wollte halt keine homogenisierte Milch haben. #00:27:40-4# Julia: Und hocherhitzt wird sie dann auch noch höher erhitzt. #00:27:45-1# Heidrun: Genau. Ja. Und deswegen, also das war eigentlich so der Hauptgrund dafür. #00:27:50-5# Julia: Praktisch wo stehst du jetzt im Moment? Du hast ja jetzt sehr, sehr viel herausgefunden, sehr viel für dich experimentiert, also wo stehst du in puncto Ernährung und auch in puncto wie geht's dir mit deiner Krankheit? #00:28:07-7# Heidrun: Im Moment mache ich ja immer noch dasselbe, was ich halt schon die ganze Zeit gemacht habe, dass ich halt, also ich befolge im Prinzip das AIP, aber ich habe für mich selber so ein paar Abwandlungen gemacht, zum Beispiel esse ich Reis, weil ich einfach gemerkt habe, dass das für mich eine gute Sättigungsbeilage ist und dass die mir überhaupt nicht schadet. Also besser als ich sage mal Kartoffelbrei oder so. Ich esse zwar auch manchmal Kartoffeln, das traue ich mich manchmal, aber das kann ich halt nicht bringen, wenn es mir gerade nicht so gutgeht. Und da muss ich vielleicht dazu sagen, wenn ich von Symptomen, also Tagen spreche, wo ich Symptome empfinde, dann ist das nicht zu vergleichen mit dem, was ich früher hatte. Also das ist alles auf einem sehr, sehr hohen Niveau jetzt mittlerweile. Mir geht's eigentlich wirklich sehr, sehr gut, aber ich weiß natürlich wie mein Darm sich anfühlt oder mein Bauch, wenn ich sozusagen ein bisschen Vorsicht walten lassen muss. Das sind dann zum Beispiel eben Tage, wo ich keine Kartoffeln essen würde, aber Reis schon. Weil Reis irgendwie für mich, also weißer Reis ist total harmlos für mich. #00:29:20-0# Julia: Interessant. Ja. Und musst du jetzt noch, nimmst du noch Cortison? #00:29:24-7# Heidrun: Nein, nein, nein. Um Gottes Willen, Cortison nehme ich schon ganz lange nicht mehr. Aber genau, also ich habe eine sehr einschneidende Veränderung nochmal jetzt erfahren und zwar nehme ich seit neuestem Humira, das ist ein ganz ähnliches Medikament wie Remicade, dieses Medikament, was mich damals eben in die Notaufnahme geschickt hat. Also ein Biologika und erstaunlicherweise vertrage ich das sehr gut, also es ist wirklich das erste Mal kann man eigentlich sagen, dass ich jetzt, das Medikament sowohl wirksam ist als auch bisher nebenwirkungsarm. Das ist sozusagen jetzt so dieser Kompromiss, den ich geschlossen habe mit mir selbst, weil ich ja jetzt studieren war. Also ich habe mich ja jetzt in meinem fortgeschrittenen Alter nochmal dazu durchgerungen nochmal ganz neu durchzustarten und ein Biologiestudium aufzunehmen. Ich habe ja vor 2 Jahren nochmal ein Kind bekommen, also mein 2. Kind und deswegen ist mein Leben im Moment wirklich sehr, sehr stressig, mein Tag ist wirklich voll von morgens bis abends bis später. Und nachts lerne ich eigentlich, wenn meine Kinder im Bett sind. Dadurch und weil Stress für mich eigentlich der wichtigste Trigger ist für meine persönliche Autoimmunerkrankung, habe ich jetzt gesagt, um diese stressige Phase irgendwie zu überstehen, dieses Studium, was mich ja eigentlich auch irgendwann mal dazu befähigen soll wirklich in die Forschung zu gehen und noch effektiver an einer Heilung für Autoimmunerkrankungen zu arbeiten, muss ich jetzt irgendwie mich dafür wappnen und mir noch ein zusätzliches Schutzschild einfach besorgen und das ist jetzt so dieses Humira. #00:31:13-1# Julia: So das war dann der Grund, warum du jetzt doch ein Medikament nimmst. #00:31:18-0# Heidrun: Ja. Weil ich halt, ich bin halt auch wirklich vom morgens bis abends unterwegs, also ich kann jetzt nicht irgendwie hier in die Hofmetzgerei irgendwie fahren und mich, also ich kann einfach nicht mehr so viel Energie und Zeit investieren wie es früher möglich war, um diese Ernährung so gut zu befolgen. Ich muss auch manchmal in der Mensa essen einfach, auch wenn ich natürlich dort kein Paleo kriege, sondern halt nur irgendwie, dann muss ich halt die Hälfte weglassen von dem, was da auf dem Teller liegt oder so. Weil es geht einfach von meinem Tagesablauf nicht mehr so gut zu integrieren, so richtig streng AIP zu essen ... #00:31:54-0# Julia: Ja. Aber es könnte ja auch sein, dass du einfach jetzt auch an einem Punkt bist, wo das durch die Arbeit, die du davor schon geleistet hast, vielleicht jetzt eher möglich ist als, wer weiß, ob das vor ein paar Jahren überhaupt möglich gewesen wäre so wie du es jetzt machst? #00:32:15-9# Heidrun: Weiß ich natürlich nicht, weil das Humira ja schon ein ziemlich effektives Medikament auch ist, aber ich denke schon, dass das auf jeden Fall ... #00:32:25-0# Julia: Ach so und das hat es damals noch nicht gegeben oder? #00:32:28-9# Heidrun: Das war vor ein paar Jahren für, also damals als ich so heftig auf das Remicade reagiert haben, da wäre das natürlich eine Alternative gewesen und die hätte mein Arzt auch gerne gemacht, aber die war für Colitis ulcerosa noch nicht zugelassen, nur für Morbus Crohn damals. #00:32:44-4# Julia: Okay. Ja, ich meine du hast das eben auch schon gesagt auch, dass du jetzt ein Studium wieder begonnen hast oder das Biologiestudium, weil es ist ja für viele von uns sage ich jetzt in der Gesundheitsszene irgendwie so, dass ja oft ein persönliches Problem, eine persönliche Reise dann der Anstoß ist dafür, dass man eigentlich sagt, man möchte sich viel, viel tiefer damit beschäftigen und das auch eine Art Lebensaufgabe, Passion wird, die man (Heidrun: Auf jeden Fall) umsetzen möchte. Deswegen auch Hut ab, dass du das nochmal angehst, weil es ist ja nicht nur eine Zeitfrage, sondern natürlich auch eine Geldfrage. Du hast auch ein Projekt oder eine wie soll man sagen ein #00:33:39-5# Heidrun: Ein Anliegen. #00:33:41-0# Julia: ein Anliegen zu dem Thema. Vielleicht kannst du kurz sagen, worum es geht? #00:33:47-2# Heidrun: Es ist halt so, dadurch dass ich ja schon einmal studiert habe und eben dieses Studium auch abgeschlossen habe, nämlich mein Übersetzerdiplom damals, habe ich, hier in Deutschland da haben wir ja Bafög und das wird eben nicht mehr gewährt, wenn man schon einen Studienabschluss hat. Das macht es halt für mich extrem schwierig, weil mit den 2 Kindern und dem sehr anspruchsvollen Studium ist es mir halt nicht möglich nebenbei auch noch zu arbeiten. Also im Gegenteil ist es sogar so, dass ich pro Semester weniger mache als eigentlich geplant ist, weil ich halt sonst mit der Kinderbetreuung einfach nicht zu Rande komme und da mein Mann jetzt auch nicht so viel Geld verdient, dass er alleine die Familie durchbringen kann, ist es halt, habe ich eine GoFundMe Kampagne gestartet und hoffe, dass #00:34:37-8# Julia: Wie funktioniert das genau, also erzähl, vielleicht kennt das nicht jeder, was ist das? #00:34:43-2# Heidrun: Ach so, wie beschreibe ich denn das am besten? Das ist im Prinzip eine Geldsammelaktion einfach. Ich versuche halt die Leute davon zu überzeugen, was ja auch tatsächlich der Fall ist, dass ich dieses Studium jetzt nicht einfach nur aus persönlichem Interesse oder weil ich das spaßig finde betreibe, sondern weil ich eigentlich wirklich an ein großes Ziel glaube und es mir ein ganz wichtiges Anliegen ist und ich glaube auch, dass viele dieses Anliegen teilen, dass eben für Autoimmunerkrankungen mehr geforscht wird, den die Autoimmunerkrankungen sind eben ein Gebiet oder eine Ansammlung von Krankheiten, die extrem viele Leute betreffen, die aber noch nicht als ein homogenes Gebiet begriffen werden anders als Krebserkrankungen und deswegen findet keine konzentrierte Forschung jetzt, die sich wirklich mit diesem Gebiet der Autoimmunerkrankungen befasst wirklich statt. Und ich fände halt schön, wenn ich daran was ändern könnte oder was dazu beitragen könnte, dass dort eben in der Richtung wirklich Fortschritte gemacht werden. Denn es gibt viele Menschen und das ist nicht so bekannt glaube ich, die mit ihren Autoimmunerkrankungen wirklich kein sehr erquickliches Leben führen. Es gibt zwar schon viele Medikamente, aber es gibt auch extrem viele Nebenwirkungen und es gibt mehr Leute als man denkt, die eben überhaupt nicht davon profitieren, bei denen die Medikamente einfach nicht gut anschlagen. Deswegen also wirklich tagtäglich sich irgendwie mehr oder weniger gut durch den Alltag schleppen. #00:36:28-3# Julia: Und ich glaube auch, weil halt auch noch die Ernährungskomponente beziehungsweise die Lebensstilkomponente im Gesamten auch was Stress und Schlaf betrifft praktisch nicht wahrgenommen wird von vielen Ärzten als ein Aspekt, der sehr viel wie man sieht in deinem Fall sehr, sehr viel beitragen kann zu einer Verbesserung der Symptome. (Heidrun: Genau) Es heißt ja nicht, jetzt nur ganz ohne Medikamente, in vielen Fällen geht's eben nicht, aber man kann einen sehr, sehr großen Beitrag und oft eine große Verbesserung irgendwie erreichen und ich denke auch dahingehend, gerade wenn man selbst die Erfahrung gemacht hat, hier mehr Sensibilität zu erzeugen, auch vielleicht in der Forschung in die Richtung zu gehen, was kann man mit Ernährungsumstellung oder mit gewissen vielleicht auch speziellem Functional Food erreichen. Wer weiß, was da weitergeht? Das heißt, wir werden natürlich auch in den Shownotes verlinken zu deiner GoFundMe Aktion und ich hoffe, dass viele, viele Zuhörer und Zuschauer dich unterstützen, denn was kann es besseres geben als jemanden, der mit so viel Passion und Überzeugung und auch diesem eigenen Leidensweg da in die Forschung kommt. Und wirklich Hut hab, dass du das auf dich nimmst wirklich #00:37:57-6# Heidrun: Ja danke. #00:37:58-1# Julia: und diesen schweren Weg gehst. #00:38:01-5# Heidrun: Ja. Ich wollte noch sagen, ein Aspekt oder ein Erlebnis oder eine Erfahrung, die mich halt auch geprägt hat und die mich auch bewegt hat dazu jetzt nochmal diesen Weg zu gehen, ist halt natürlich auch die Tatsache, dass ich gemerkt habe, dass die Ernährung alleine einen eben doch nicht heilt. Das möchte ich mal hervorheben, denn ich glaube, das ist vielen in der Paleo-Szene auch nicht so richtig klar, das, was man immer in den Foren liest, ist ja ein kleiner Ausschnitt und die Leute, denen die Ernährung nicht geholfen hat, die verlassen die Foren ganz schnell wieder. (Julia: Genau) Deswegen es gibt dieses Confirmation Bias sozusagen, was eben ganz bekannt ist auch in den Gruppen, dass, wenn man jetzt da neu reinkommt als Patient und man möchte halt natürlich, man möchte hören, man möchte Erfolgsstories hören, man fragt teilweise explizit danach: Wird mir denn diese Ernährung helfen? Und dann hast du teilweise einen Threat, wo wirklich 15, 20, 30 Leute schreiben: Ja, mir hat die Ernährung super geholfen und ich bin jetzt gerade total beschwerdefrei und so weiter. Oftmals sind genau die gleichen Leute ein halbes später schon nicht mehr in der Gruppe, eben weil sie nicht zugeben wollen, dass es dann doch wieder, dass sie einen Rückfall hatten oder so. Das ist leider diese Dynamik dann in diesen Gesundheitsgruppen, dass ein Rückfall auch als Scheitern betrachtet wird und man deswegen sich dann irgendwann nicht mehr traut um Hilfe zu fragen. #00:39:30-7# Julia: Das ist natürlich sehr schade dann, weil es eben wieder dieses "Ganz oder gar nicht" oder einfach diese Null und Eins, weil wie gesagt, glutenfrei und getreidefrei zu sein, das kann auf keinen Fall schaden und wenn es ein bisschen hilft, ist gut (Heidrun: Genau) und dass das einfach nicht das Wunderheilmittel ist. #00:39:54-5# Heidrun: Für manche vielleicht. Also es gibt ja immer wieder Fälle ... #00:39:57-9# Julia: Ja. Genau. #00:39:59-2# Heidrun: wo wirklich nichts Anderes dann mehr nötig ist, gerade bei, also ich habe es eigentlich vor allen Dingen bei Leuten beobachtet, die wirklich gleich nach der Diagnose so wie wir jetzt Glück hatten von der SCD oder Paleo zu hören, und sehr, sehr gute Erfolge ... #00:40:13-2# Julia: Macht Sinn. Ja. #00:40:12-8# Heidrun: keine Medikamente mehr nehmen. Aber bei mir war es halt, sind schon 10 Jahre ins Land gegangen nach der Diagnose und bei mir war es halt einfach nicht so, dass ich (Julia: Genau) wirklich sagen konnte, das ist es jetzt, bin komplett symptomfrei und brauche nie wieder was Anderes. #00:40:29-5# Julia: Ja. Das muss man sicherlich sehr differenziert betrachten. Ich möchte noch auf 2 Sachen hinweisen, einerseits hast du einen Blog, das heißt urgesundheit.de, wo du auch immer wieder sehr interessante Artikel schreibst beziehungsweise auch ein bisschen über das, was wir jetzt gesprochen haben, über deine Geschichte. Und dann hast du noch ein Buch geschrieben, das heißt "Die Paleo-Revolution: Gesund durch Ernährung (Heidrun: Ich zeige es mal eben) im Einklang mit unserem genetischen Erbe". Genau. Auch da werden wir natürlich verlinken. Da können dann die Zuhörer und Zuschauer sicher nachlesen, was du jetzt auch erzählt hast und ... #00:41:15-1# Heidrun: Darüber berichte ich gleich am Anfang ganz ausführlich über meinen, wie ich dazu gekommen bin überhaupt. #00:41:20-9# Julia: Okay. Ich bin mir sicher, dass das auch ein guter Start ist, wenn jemand sagt: So. Ich möchte jetzt das gerne ausprobieren. Dann kann ich jedem nur dieses Buch empfehlen und da einfach mal das als einen Startpunkt sehen und wie wir gesagt haben. Es ist für wenige, es kann für manche tatsächlich die die Heilung sein, aber für die meisten wahrscheinlich nicht. Aber es gibt den richtigen Anstoß sage ich mal in die richtige Richtung und das ist ... #00:41:48-0# Heidrun: Ja. Auf jeden Fall. Also für mich hat es mein Leben verändert. Das ist auf jeden Fall so gewesen. Schulde ich der Paleo-Ernährung auf jeden Fall einen lebenslangen Dank. Das war für mich schon die Rettung irgendwo auch. #00:42:02-7# Julia: Ja Wahnsinn. Liebe Heidrun, danke für dieses tolle Interview. #00:42:08-7# Heidrun: Ich danke dir, dass du mich eingeladen hast. Es war sehr schön mit dir zu plaudern. #00:42:13-3# Julia: Ganz meinerseits. Hat mich wirklich wahnsinnig gefreut und ich denke das waren wieder super viele Informationen und ich bin mir sicher, es gibt eben wie du sagst, es gibt so viele Menschen, die an Autoimmunerkrankungen leiden und das ist eben nicht nur ... #00:42:29-2# Heidrun: Und immer mehr. #00:42:29-6# Julia: Colitis Ulcerosa, sondern eben noch viele, viele andere und immer mehr. Es steigt, es ist praktisch wie eine Epidemie, es gehört zu den Zivilisationskrankheiten so wie Diabetes und Krebs und es ist logisch, dass auch diese Erkrankungen ansteigen mit dem falschen Lebensstil, der das Ganze natürlich oft noch unterstützt. Deswegen bin ich mir sicher, dass ganz, ganz viele Leute da was mitnehmen können und vielleicht einerseits dich unterstützen bei deiner Erforschung oder auf dem Weg in die Forschungsposition und dass sich da bald auch etwas ändert beziehungsweise natürlich auch das Buch kaufen und hier vielleicht für sich selbst etwas, einen Schritt in eine bessere Zukunft gehen. #00:43:17-7# Heidrun: Ja. Das hoffe ich auch. #00:43:20-8# Julia: Also dann, Tschüss! #00:43:22-7# Heidrun: Tschüss! Mach's gut! #00:43:24-1# ##Unterstütze Heidrun und hilf ihr auf ihrem Weg in die Forschung Heidrun ist Ehefrau und Mutter von zwei kleinen Kindern. Jeder, der selbst Familie hat weiß, wie viel Kraft und Zeit da benötigt wird. Angespornt durch ihren eigenen Erfolg und durch die eigenen Erfahrungen mit einer Autoimmunerkrankung, hat sie sich entschlossen noch einmal zu studieren. Heidrun studiert Biologie um später in der Forschung arbeiten zu können und um die Welt zu verändern. Da sie nun Vollzeit studiert und für ihre Kinder da sein muss, kann sie nicht mehr arbeiten gehen. Das ist eine große finanzielle Belastung für die Familie! Du kannst Heidrun mit einer Spende unterstützen!! Schau auf www.gofundme.com und hilf Heidrun dabei die Welt zu verändern! Bücher Die Paleo-Revolution: Gesund durch Ernährung im Einklang mit unserem genetischen Erbe - Heidrun Schaller Dieses Buch erklärt wissenschaftlich fundiert, aber auch für Laien verständlich, warum die sogenannte Paleo- oder Steinzeit-Ernährung für Kranke wie Gesunde die optimale Ernährungsform ist. Selbst im Alter von 25 Jahren von einer schweren chronischen Krankheit aus der Bahn geworfen, ging die Autorin den Dingen auf den Grund, anstatt sich mit Krankheit und Nebenwirkungen abzufinden. Nach langer Suche und dank ihrer Verbindungen in die USA stieß sie auf die Paleo-Ernährung die ihr Leben von Grund auf zum Positiven wendete. Denn diese Ernährungsform birgt ungeahnte Chancen für Menschen mit chronischen Erkrankungen sowie viel Potenzial für ein gesünderes Leben. Weitere Folgen Ich habe Hashimoto: So hilft mir Low Carb dabei - Interview mit Daniela Pfeifer Diabetes (Typ 1) mit ketogener Ernährung besiegen, geht das? - Interview mit Jeff Heusserer Artikel Heidruns Geschichte auf urgesundheit.de Breaking the Vicious Cycle SCD Lifestyle Dr. Axe über SCD Webseiten Heidrun Schaller Paleo Low Carb - JULIAS BLOG | (auf Facebook folgen)

united states amazon art master interview internet man sports college pr fall passion stress land seattle blog trip transition patients leben welt android thema threats phase weg als male zukunft deutschland arbeit geschichte manifestation mehr dinge kinder erfahrungen trend rolle geld trigger diabetes zeiten kraft gedanken wochen familie grund durch alltag snacks reise bei erfolg probleme gesch ganz buch anfang mensch ziel sommer hilfe lebens fokus meinung energie beispiel projekt haus suche essen erfahrung gut schritt weise tagen bio gesundheit vielleicht sache butter leute selbst entscheidung dank stunden unterschied monaten praxis wasser protein chancen kindern jeder mutter weil genau punkt monat ern amerika recht sinne interesse luft foto mach dingen ding unterschiede ganze beitrag sachen produkte hintergrund richtung reis ergebnisse studium gruppe krankheit ach problemen methoden kontrolle mir gesicht erfolge teile diagnose habe autorin hut paleo gleichzeitig prozent tee deswegen bett schlaf bevor einstieg tat risiko szene forschung potenzial australien arzt kamera niveau gegenteil scheitern obst alternativen sprung theorie bahn gruppen therapie erlebnis semester prinzip haas leuten phasen krankheiten freizeit fleisch rande krebs heilung teller gebiet dorf brot dadurch effekt hashimoto schau zuschauer bauch axe fett einladung konzepte krankenhaus anteil orientierung behandlung genuss brie aspekt hinweis tatsache heidelberg zeug vorsicht rettung gewicht aussicht einklang perfekt eben urspr anliegen symptome belastung gemeinsamkeiten eier erbe buches erkrankung lebensstil low carb schlag abk ergebnissen somit erkrankungen schock verbesserung berufsleben milch magen beschwerden verbindungen dynamik zutaten aussehen medikamente fortschritte tsch betrachtung nebenwirkungen geboren abitur mensa erfolgen sau biologie testen spende confirmation bias durchf honig gesunde im gegensatz oftmals aspirin ausschnitt darm leber ehefrau quark remission anderes diplom positiven bakterien kompromiss entz symptomen abschnitt futter mengen dosen epidemie colitis ansto flecken sensibilit kalorien au pairs kartoffeln teilweise erforschung medikament konnte tropfen kranke tagesablauf enzyme tomaten teufelskreis fette laien schaf kinderbetreuung antik aip schub ratschlag fructose auffassung vollzeit schwelle protokoll komplikationen vicious cycle eiern scd bauchschmerzen durchfall kohlenhydrate notbremse eile notaufnahme foren gelenke joghurt stipendium vollkommen feststellung niere startpunkt gewichtszunahme unvertr mandeln ziege verzweifelt kinderarzt ansammlung studienzeit erscheinungen strohhalm nebenwirkung rheuma ausdauersport hauptgrund baf leidensweg die diagnose steckenpferd linguistik gewichtsverlust kohlenhydraten herr dr schutzschild kokosnuss kuhmilch humira vermehrung stressfaktor schubs heidrun gesamten die symptome darms speiser blutbild laktose darmerkrankungen der hintergrund morbus crohn packungen milchprodukten frischk glukose darmspiegelung immunzellen functional food krebsrisiko fertigprodukte colitis ulcerosa dickdarm verwandter auberginen um gottes willen cortison specific carbohydrate diet viele patienten darmerkrankung autoimmun studienabschluss verdauungstrakt kortison schleimhaut ziegenk erfolgsstories remicade paleo ern abwandlungen moment du nachtschattengew nierenfunktion schulmediziner blutverlust biologiestudium immunsuppressiva verdauungstraktes blutpl specific carbohydrate diet scd behandlungsoption elaine gottschall hauptstudium methotrexat darmerkrankungen ced azathioprin
Nature Biotechnology Podcast
First Rounder: Jan Vilcek

Nature Biotechnology Podcast

Play Episode Listen Later Jun 8, 2017 65:25


Jan is the co-founder, CEO and chairman of the Vilcek Foundation, and also a long-time researcher and professor at New York University's School of Medicine. His conversation with Nature Biotechnology covers his harrowing childhood in Czechoslovakia during the rise of Nazi Germany and World War II, his escape from communist Czechoslovakia through defection, and his role in the discovery of the blockbuster drug Remicade. See acast.com/privacy for privacy and opt-out information.

DPL-Surveillance-Equipment.com
Bioelectronics: The Future of Medicine

DPL-Surveillance-Equipment.com

Play Episode Listen Later Jun 19, 2016


Click Here Or On Above Image To Reach Our ExpertsBioelectronics The Future of MedicineBioelectronic medicine is a scientific discipline that brings together molecular biology, neurophysiology, neurotechnology and analytics to develop nerve-stimulating technologies to regulate the molecular targets underlying disease. This approach promises to deliver therapies superior to pharmaceuticals in terms of efficacy, safety, and cost, without significant side effects.At the core of bioelectronic medicine is the electrical signal used by the nervous system to communicate information. Virtually every cell of the body is directly or indirectly controlled by these neural signals. Bioelectronic medicine technologies can record, stimulate, and block neural signaling. Bioelectronic medicine will change the way we treat diseases, injuries and conditions such as rheumatoid arthritis, Crohn's disease, diabetes, paralysis, bleeding, and even cancer.The functions and organ systems of our body are, to a significant extent, controlled by electrical signals that travel along the nerves. Bioelectronic medicines will aim to control biological processes and treat disease by modulating these electrical impulses.They will be miniaturized devices that connect to specific groups of neurons or their nerve fibres and modulate the electrical signaling patterns, to restore the healthy states of targeted organs and functions.Imagine a world where we treated deadly diseases with electricity instead of pills or chemo.We might not be as far from this reality as you think.Normally, our nervous systems send signals to our tissues and organs to suppress inflammation, a phenomenon known as the inflammatory reflex. But sometimes, this system gets out of whack, and can even result in diseases like rheumatoid arthritis and inflammatory bowel disease.Traditionally, doctors have treated these diseases using drugs designed to suppress inflammation, such as infliximab (trade name Remicade) oradalimumab (Humira). But these drugs are expensive. Plus, they don't work for everyone, often come with nasty side effects, and sometimes, although rarely, they can even kill.Now, some researchers have found a way to deliver electrical stimulation to just the right areas to stop chronic inflammation in its tracks — a therapy they're calling bioelectronic medicine.-------------------Related Article:Achieving Optimum Health By Understanding Biological Frequencies:  Nikola Tesla Said, "If You Could Eliminate Certain Outside Frequencies That Interfered In Our Bodies, We Would Have Greater Resistance Toward Disease". PRO-DTECH II FREQUENCY DETECTOR(Buy/Rent/Layaway)An Accidental DiscoveryLike many great ideas in science, this one came as an accident. Neurosurgeon Kevin Tracey, the president and CEO of the Feinstein Institute for Medical Research in Manhasset, New York, and his colleagues were studying a chemical that blocked inflammation in the brain, when they found it also decreased inflammation in the spleen and other organs. CELLPHONE DETECTOR (PROFESSIONAL)(Buy/Rent/Layaway)At the time, "we didn't understand how the brain could be communicating with the immune system," Tracey told reporters.PRO-DTECH III FREQUENCY DETECTOR(Buy/Rent/Layaway)As it turns out, the body has an inflammatory reflex that controls how we respond to injury or infection.PRO-DTECH III FREQUENCY DETECTOR(Buy/Rent/Layaway)The Inflammatory ReflexWhen the body senses an infection or injury, the brain is notified via the vagus nerve, which relays information from the heart, lungs, and other abdominal organs.But it's a two-way street: The brain also sends electrical signals via the vagus nerve to the organs, tamping down the production of inflammatory molecules.PRO-DTECH III FREQUENCY DETECTOR(Buy/Rent/Layaway)Tracey and his colleagues have found a way to restore those signals, by implanting tiny electronic devices that can deliver targeted electrical shocks to the vagus nerve.The electrical therapy is already being tested for some diseases.WIRELESS/WIRED HIDDENCAMERA FINDER III(Buy/Rent/Layaway)A company Tracey founded, called Set Point Medical, has conducted clinical trials of this technology in Europe for treating rheumatoid arthritis, and the results have been promising. PRO-DTECH IV FREQUENCY DETECTOR(Buy/Rent/Layaway)But is the stimulation treating the cause of the disease, or merely the symptoms? Possibly both, though we will only know after more studies, Tracey said.ElectRxResearch like Tracey's has inspired broader interest in bioelectronic medicine.Wireless Camera Finder(Buy/Rent/Layaway)The US military's research and development branch, the Defense Advanced Research Projects Agency (DARPA), launched a program in fall of last year called ElectRx to fund research on electrical treatments for various diseases.MAGNETIC, ELECTRIC, RADIO ANDMICROWAVE DETECTOR(Buy/Rent/Layaway)The ElectRx program aims to make it easier to deliver the electrical stimulation in a way that is both minimally invasive and precisely targeted, Doug Weber, a DARPA program manager and bioengineer at the University of Pittsburgh, told Business Insider.COUNTERSURVEILLANCE PROBE / MONITOR(Buy/Rent/Layaway)This type of therapy still has a long way to go before it's widely used. Today's therapeutic devices are pretty blunt, consisting of large electrodes that stimulate an entire nerve, when you may only want to target a small fraction of nerve fibers."We want to be able to identify specifically those fibers for therapeutic benefit, and have the technology to target those fibers directly," said Weber.PRO-DTECH FREQUENCY DETECTOR(Buy/Rent/Layaway)Beyond funding devices that would treat disease, DARPA said they also plans to fund projects designed to constantly monitor the body and potentially detect disease if and when it starts.Last month, DARPA selected the ElectRx proposals it plans to fund, and is in the process of finalizing the contracts. The program will officially kick off in October, Weber said.RF SIGNAL DETECTOR ( FREQUENCY COUNTER)(Buy/Rent/Layaway)Your questions and comments are greatly appreciated.Monty Henry, Owner (function () { var articleId = fyre.conv.load.makeArticleId(null); fyre.conv.load({}, [{ el: 'livefyre-comments', network: "livefyre.com", siteId: "345939", articleId: articleId, signed: false, collectionMeta: { articleId: articleId, url: fyre.conv.load.makeCollectionUrl(), } }], function() {}); }()); Additional Resources: * Prevention and Detection of Electronic Harassment and Surveillance* 

The Bio Report
Seeking a Best-in-Class Antibody at Bargain Basement Prices

The Bio Report

Play Episode Listen Later Mar 3, 2016 15:35


Bird Rock Bio, a small, San Diego-based biotech, is planning to take aim at some of the biggest biologics on the market with an antibody in development to treat rheumatoid arthritis that it says it expects to market at an annual cost of just $2,000 a year. That compares to around $30,000 a year for drugs such as Humira, Remicade, and Enbrel that are TNF inhibitors. The experimental therapeutic known as Gerilimzumab targets IL-6. We spoke to Paul Grayson, president and CEO of Bird Rock Bio about the company, the benefits of targeting IL-6, and how the company expects to be able to offer the drug at such a disruptive price point.

The Opperman Report
Matt Winacott: Remicade For Cheryl

The Opperman Report

Play Episode Listen Later Feb 29, 2016 4:06


My name is Matt Winacott, I would like to raise funds for my girlfriend Cheryl. She has a very rare disease called Takaysu Arteritis. It is defined as a rare type of vasculitis, a group of disorders that cause blood vessel inflammation. Her particular case affects her carotid artery which is the main blood vessel in your neck going to your brain. This artery has been severely damaged from inflammation and her condition is serious. Her life is in immediate danger. Her disease is very active right now and the only medication that is helping her is called Remicade. Remicade put her in a state of remission at one point and she needs it to keep her fight going.Remicade costs $3200 for 1 infusion. The infusion is every two months, March is covered but she needs help for May. Her insurance company recently denied her long term disability and her coverage for Remicade has been stopped.This has been a huge stressor for her. She also has been dealing with severe depression and anxiety. Her ex-husband left her while she was hospitalized initially 4 years ago, took all the money, charged up credit cards and left her for another woman. She battled that and her disease and went into remission- she is a fighter. While trying to rebuild her life again, she was brutally sexually assaulted by two men while waiting for a bus. She has cried a lot and has had so much pain. With all that has happened to her, she is trying her best to recover and get the help she needs! Cheryl is a very sweet, kind, and loving girl and she has a very huge heart. We need to help her get better! Your support for her Remicade infusion would be very appreciated! Thank you!This show is part of the Spreaker Prime Network, if you are interested in advertising on this podcast, contact us at https://www.spreaker.com/show/1198501/advertisement

remicade
IBD Round Table Discussion ( Video ) – The Crohn's Colitis Effect

We’ve got another exciting episode this month!!! We discuss #DDW14 ( Digestive Disease Week 2014 ) in Chicago, Janssen Biotech (makers of Remicade ) and the #IBDSocialCircle meeting, plus #WorldIBDDay 2014. Episode 12 Panelist are Frank Garufi Jr., Sara Ringer, Marisa Lauren Troy, and Ryan Stevens The post Episode 12 – #DDW14 and #WorldIBDDay appeared first on The Crohn's Colitis Effect.

Medizinische Fakultät - Digitale Hochschulschriften der LMU - Teil 02/19
Therapie der Spondylitis ankylosans mit dem monoklonalen chimären anti-TNF-Antikörper Infliximab (Remicade®):Klinische Wirksamkeit und Einfluss auf die HLA-Oberflächenexpression auf Lymphozyten mit besonderer Berücksichtigung von HLA-B27

Medizinische Fakultät - Digitale Hochschulschriften der LMU - Teil 02/19

Play Episode Listen Later Jun 24, 2004


In der vorliegenden Arbeit wurden therapeutische und immunmodulatorische Effekte einer TNF-Blockade bei Patienten mit aktiver Spondylitis ankylosans untersucht. Hierzu wurde an 10 Patienten während einer 60wöchigen Infliximabtherapie eine Evaluation von Therapiewirksamkeit und -sicherheit, sowie eine durchflusszytometrische Analyse der HLA-Oberflächenexpression auf Lymphozyten vorgenommen. Von 8 Patienten wurde die Therapie ohne ernste Nebenwirkungen gut vertragen und führte zur raschen und dauerhaften Verbesserung der klinischen, laborchemischen und radiologischen Verlaufsparameter. Ein Patient entwickelte nach initialer Wirksamkeit ein sekundäres Therapieversagen, bei einem weiteren Patienten wurde die Therapie unter dem Verdacht eines medikamentös induzierten Lupus-Syndroms abgebrochen. Gegen Mitte des Behandlungszeitraumes konnte ein am deutlichsten auf den B-Lymphozyten ausgeprägter Anstieg der HLA-B27- und MHC-Klasse-I-Expression beobachtet werden. Die Expressionszunahme ist möglicherweise Ausdruck immunmodulatorischer Effekte, die mit der langfristigen Therapiewirksamkeit assoziiert sind. Für die Zunahme der Oberflächenexpression kommen folgende Mechanismen in Frage: 1. eine vermehrte intravasale Kompartimentierung primär hoch exprimierender Zellen oder 2. eine durch die TNF-Suppression induzierte Hochregulation einer zuvor niedrigeren HLA-B27-Oberflächenexpression. Angesichts unserer Ergebnisse und der aktuell in der Literatur verfügbaren Daten halten wir letzteren Mechanismus für wahrscheinlicher. Innerhalb dieses Erklärungsmodells ist die bei Therapiebeginn niedrigere HLA-B27-Expression bedingt durch die Expression einer verminderten Anzahl von HLA-B27-Molekülen oder aberranter β2m-freier Varianten, die durch die von uns verwendeten konformationsabhängigen Antikörpern nicht detektierbar sind. Unter Hemmung des TNF-Einflusses kommt es schließlich zur schrittweisen Wiederherstellung der physiologischen Prozessierung trimolekularer HLA-B27-Oberflächenantigene mit konsekutiv vermehrter AK-Bindung. Eine verminderte oder aberrante HLA-B27-Expression ist möglicherweise mit immunmodulatorischen Effekten im Sinne einer erhöhten Zelldepletion assoziiert. Durch die Reexpression trimolekularer HLA-B27-Moleküle wird die Interaktion zwischen immunkompetenten Zellen und HLA-B27-positiven Zellen beeinflusst, wodurch das Zellüberleben begünstigt wird. Dieser Erklärungsansatz ist vereinbar mit dem gegenwärtig favorisierten pathogenetischen Modell der fehlerhaften HLA-B27-Prozessierung und der derzeit diskutierten Beteiligung von TNF bei der Manifestation der AS.

Benzinga LIVE
Sell The Rip In Stocks?

Benzinga LIVE

Play Episode Listen Later Jan 1, 1970 59:14


BENZINGA CANNABIS CAPITAL CONFERENCEThe premier gathering of cannabis entrepreneurs and investors in North America returns for a 2-Day Hybrid Event on October 14-15.Speakers will include $SNDL and other major Cannabis Companies, for more information visit https://www.benzinga.com/events/cannabis/Episode Summary:Thursday TradesStocks talked about on the show:$INTC $UPST $SOFI $SWBI $VIAC $STAB $NGTF $SOVOGuests:Daniel Creech Curzio Research 2:00 Statera Bio CEO Mike Handley $STAB 10:00 Nightfood CEO Sean Folkson $NGTF 30:00SOVOS CEO Andy Hovancik $SOVO 45:00https://www.curzioresearch.com/Hosts:Aaron BryTwitter: https://twitter.com/aaronbry5Hot Stocks Luke JacobiTwitter: https://twitter.com/lukejacobiJason RaznickTwitter: https://twitter.com/jasonraznickSubscribe to all Benzinga Podcasts hereGet 20% off Benzinga PRO here Become a BENZINGA AFFILIATE and earn 30% on new subscriptionsDisclaimer: All of the information, material, and/or content contained in this program is for informational purposes only. Investing in stocks, options, and futures is risky and not suitable for all investors. Please consult your own independent financial adviser before making any investment decisions.Unedited Transcript All right. All right. What's going on, everybody having. Whew. We are back at it, wine and down the end of the week, another dreary to Detroit day here behind me. I hope everybody's got a little bit more sunshine than we do. It's also very cold. I'm now wearing a light jacket in the morning, but what's going on guys.Market is ripping again. We are back to where we were before that Monday sell off, you buy the dippers out there. All of you by the dippers. I was not wanting. Congratulations to you. Round of applause, pat yourself on the back, you won a game. Uh, you know, I'm going to go ahead. Let's just look at this, this chart aspire really quick for a second, and we're going to zoom it out to a year and then we'll go to five years.Uh here's the one year chart is by, by the day. Tried and true. Uh, here's a two-year charter spy by the dip tried and true five years. All right. I guess at the, by the dippers, just always seem to win this one. Uh, but what's going on guys? This is the power hour. This is the trade idea show. That's why we spend this time together every single day.So if we are not delivering on ideas, call us out. You are empowered to do that in the chat. We're going to get rocking and rolling. Uh, first op we're bringing in Daniel from Curzio reading. Good. Good, good friend to Frank over there. Uh, and Daniel's going to be dropping some ideas on us. He's gonna be talking about the China situation a little bit, I believe.Uh, and then we, we have three public company CEO interviews today. Jam pack guys. Okay. Three public company's CEO interviews. A lot of them may be stocks that you're not familiar with. I'll give you the tickers there. S T a B N G T F and S O V O. Uh, so, so again, S T a B N G T F S O V O a, but without further ado guys, uh, let's go ahead and bring Daniel from Curzio research in there.And when you, if you have takers, drop them in the chat, uh, I see, et cetera, ETCs already go and he's got his affirm on there. He's got his hymns on there. Um, and, and, yeah, let's get these in here. Solar ops. We're talking about the cannabis. I am not in any of the cannabis stocks now, but, but, but maybe I ought to be, but let's ask Daniel, Daniel, are you in any of the cannabis names?Um, not right now. No, but, uh, they've been coming across the headlines a lot. And first of all, thanks, thanks for having me great to be here. Um, but if I were to look at something in full disclosure, I don't have it and I've been kicking myself, but , uh, if you want to pull that up, there are basically a roll-up company that does a medical marijuana and the facilities that they're going to use to produce and grow and distribute.And that's char has been absolutely beautiful from an investor standpoint. Five-year chart. Yep. And, uh, those guys, uh, I believe it's wall street guys that just got together and man, they they've just been knocking it out of the park. So that's the one that I would look at first, other than the big names Tilray and those et cetera.But man, a friend of mine gave me that under a hundred and I just kept thinking, all right, I'll wait and wait and wait. And, uh, that's, that's frustrating, but that's investing that's okay. Uh, and, and Daniel, but before we hop into it, uh, give me a little bit of your background. Tell us, tell us about your trading investing career.Um, and then let's dive into some time. Absolutely. So I joined a Frank Curzio here at Curzio research. Uh, coming up on four years. It'll be four years this October next month. And my background before that was, I started in the brokerage business as a financial advisor, uh, had series seven and 66. Then didn't enjoy that.I like the research side, but not the front office standpoint. They believer in savings and investing. And on the saving side, I'm big into whole life insurance as a, as a wealth management tool. I know that raises a lot of red flags and always gets a good conversation started, but that's for another time, I can argue that until I'm blue in the face.And, uh, then when I was listening to Frank's podcast and following him through his career, and when he said that he was starting his own shop and wanted an analyst, I threw my hat in the ring and here we are going on four years. Uh, and give it, give us the short insurance pitch. The short insurance pitch is if you're disciplined enough to say, if you compare a whole life insurance policy to a bank account, there's no other product out there that is quote unquote as safe and reliable.And it gives you the opportunity to earn interest as you use your money. And there's a big difference between the interest you earn and the interest you pay with the flexibility on that. It's a fantastic wealth building opportunity over the long term. It's not a trading deal. Uh, if you're, if you're old right now and I don't mean to be rude about that, uh, that's what, you know, everybody thinks they're too old for everything these days, but, uh, if you're anywhere under, I'd say 50, you ought to really give it a look and most policies are set up.In favor of the insurance company, meaning higher commissions, and you can split those premiums up and infinite banking process. If you Google that, you'll, you'll see a lot of good stuff. Uh, infinite banking by, uh, Nelson Nash. I believe I'll tell my head as a great book to dig into. All right, there we go.And if anybody has a question about the insurance side, dropped them. And I'll pass it along to Daniel, but all right. Let, let, let, let's get back to the stock side. What what's on your radar right now? What are you thinking about? We, you, you gave us a cannabis name to look at already, but, but what else?Yeah. And that was driven by, uh, you know, if you, you guys are all market junkies. So as you're looking at headlines and everything, uh, the biggest lesson that I'm learning and, you know, I don't have a crystal ball or anything, but you gotta be able to decipher. News to act on and what to ignore. And when you just, when your market junkies and you see a lot of things coming across your desk or your eyes, uh, in my opinion, headlines around pot stocks kind of went away and now they're coming back and I say, they're coming back over the last month, at least in my opinion.So, uh, and that's driven politically, uh, there's a lot of headlines about, um, there's a group of. I think there's a bill in the house or the Senate. I'm sorry, I don't, I'm on the fence there about protecting banks that do business with, uh, pot stocks, because that's a big red flag right now. Cause you still have this illegal NIS at a certain level.I mean, it's kind of scary to think about, Hey, the feds can basically go in and shut anything down, but we're not going to. So we're in this process of, Hey, this is a law, but we're going to ignore that. Uh, we see a lot of that with politicians on both sides of the aisle. So that's not anything new. That's, you know, I look through the world from a political and economic lens.Uh, I think everybody should do that because it literally affects everything in our lives, in reality, as consumers and individuals. Okay. Alright. And I'll, I'll draw, I'll throw mine in the ring too. I'm going to throw in the, the one that everybody thinks about, but till Ray, uh, Erwin Simon, CEO of Tilray founder of Hain, celestial, good friend of Benzinga.Um, I, I, he he's, I followed his career for quite a while and he's just such an incredible operator. Um, and, and so if I had to pick one, I'm picking the track record of, of, of his, on the management side and that's where Tilray would be my plate. And that's great because you want to focus on individuals. I mean, when you, when you don't have an investment that you can control, so it's not close to the vest you want to invest in management teams.Um, Frank talks a lot about that with, especially in the resource sector, you want proven management teams, you want skin in the game. So if that gentleman and you know him like that, that that's a, that's a check mark on the, on the good side for the teacher. Yeah, absolutely. All right. Well, what else is on your mind?You know, Yeah, we'll go from a boring to exciting. So low-hanging fruit. Uh, Intel has dropped the ball for a number of years. They've let you know, their lunch has been eaten by their competitors. They have a new CEO and I'm going to butcher this, but pat gins learner, and he just took over in February of this year.And I think that this is a situation where you can buy it and forget about it. I have a little bit of a full disclosure. You earn a decent yield. And I think that as there's more volatility in the markets, and if you see this transition from growth to value, like everybody's warning about or volatility, you're going to go into hard brand names, solid brand names with good balance sheets.And they. Just have to quit screwing up all the time, in my opinion, to get a higher price, uh, the new CEO's got big ambitions. That's what I like to see either. They're going to invest a lot in fab centers, uh, semiconductor buildings over the next several years. And that's a huge secular bull market.That's not going away anytime soon. So Intel, if it's not exciting, But I do think that that's the lowest hanging fruit out there on a, on one of the big, yeah. And looking at some of the multiples really quick. I mean, it seems like a pretty cheap stock. So we're looking at a forward PE ratio of 12. Um, I don't have the S and P 500 handy, average handy off the top of my head.Right. At least in the twenties, uh, and then a price to sales, a 2.8 versus that one I know S and P average is, is a little bit over four. So, so it definitely seems like a relatively cheap stock. Yeah. And you can argue, I mean, the, the lower PE uh, forward P against its peers is warranted right now, because again, they've been dropping the ball so many times, so this new CEO starts to get some momentum, starts to prove that they can show results.I think that you can see that P rice faster than the actual results in reality. Markets are always forward-looking and that's exciting. That can be good or bad, but again, you get a few, uh, you get a few check marks on this guy's side, and I think it could just take off and easily be, you know, 20, 25% and then kind of find that new normal and hang out there for awhile.And again, you get paid to wait and are you really worried about Intel going bankrupt? I'm not, but you know, that's a good, that's a good hiding spot. And I don't think it's going to be dead money going from. Yeah. And check this out guys. I, I just, I just want it up an income statement really quickly. Uh, you know, th this, this top number that we have here that I'm trying to highlight, uh, th th this is quarterly revenue, and I mean, we're looking at like five quarters in a row with.Literally no growth. Um, you know, we, we zoom it out to annual revenue and we're getting a little bit of growth there. Um, but, but not, not crazy exciting. I think that's what Daniel's referring to. Yep. Absolutely. All right. All right. What else you said you're gonna start pouring and taking. That's boring. So a upstart U P S T is the taker and a quick, uh, are you familiar with this company at all?I am going to Lockton. Who's also a good friend of Benzing as is very, very hot on this stock. A couple of times to us it's been absolutely going crazy lately and quick, a rabbit trail here. You guys need to be going through 13 F filings. Uh, there's free websites out there and that's just great use the power of the internet.We've never lived in a better time where guys like me on 35 can take advantage of, I mean, the amount of resource we have or the amount of information we have for free right now over the internet. It's just a huge step forward and it's just blind, dumb luck that we get to live in this period. None of us picked when we got to be born in order to get some of this information at all, you'd have to go to libraries, different things.So take advantage of there's 13 S I was going through those, uh, Dan Loeb of third point. Somebody I really respect and you know, like to listen to anything he writes or says and read anything he writes. So I just saw this in a filing and I just went through ticker symbols. Um, they're in a major growth platform where the banking and financial services are using a lot of AI.They have been for some time, but it's getting a lot of capital to flow into that space right now. So they do personal loans, consumer loans, and they basically go in and show banks, Hey, we can show you how to make more loans with a. Risk tolerance and a lower default rate. And why wouldn't you pursue that or look into that if you're a bank and that's a scalable business with all the loans and trillions of dollars out there.And as you can tell, I would wait for a pullback. This is definitely a momentum stock. Uh, we were just talking about, uh, PEs with, uh, Intel. I don't know what it is off the top of my head, but it's gotta be through the roof on. All right. And, and I want to throw this one out to the chat to, uh, is anybody in this Docker to anybody get into the stock from the show?Because when we first talked about it, it was in the seventies somewhere. I, this is the first time I've looked at it in a wild scene, three 40. I, I clearly missed the boat. Uh, but, but I'm curious if anybody out there caught the rip in this one. And so, so Daniel, I like, I like what you're picking up on it that you want to wait for for some of that pullback and.Let's let the momentum co come to a close, um, with the model like you're saying is so good. It's so reoccurring too, right. Is once a bank becomes dependent on upstart for, for lending and being like a core part of that engine is as to how they're pricing and deciding who to lend to. I would imagine that that's impossible, damn near impossible for these banks to rip out of their operations.Yeah, absolutely. It's, it's a sticky product and it's scalable. So as an investor, that's a great thing to have. So, you know, be, be prepared for volatility. Um, I, quick story. I told my dad about this around $95 a share, and I said I was buying it and I didn't. And he did, and I wasn't lying to him and it went.50 or whatever. And now look at where it is. He didn't sell it. So he's very happy. But of course I was kicking myself. I think I bought a gold stock or whatever, which I'm still down on. Uh, but I said, Hey, you need to buy this. I should buy this, but I'm going over here. And he did. So that's good. All right guys, and check out the quarterly revenue on this one.We're looking at four quarters of data right here on upstart again, sticker U P S T. We went from $51 million of sales to $194 million of. In four quarters. That's I don't know if there's other public company that operates at this scale that, that that's had that kind of growth. I mean, that's, that would be, if somebody out there wants to go run a quick stock screen, so set maybe market cap threshold somewhere, uh, or, or may set a revenue threshold outlet, like 50, a hundred million dollars and see if any other companies have this kind of growth.I, I would imagine that that there's not one. All right. So, so you're making it more exciting. Do you have a third one for us? Yeah. Along the same lines with the financial platform online platform, a sofa Jeffrey's just came out with initiation yesterday. I've been watching this. It's been volatile as well, and they put a PR $25 price tag it, price target on.If I, uh, if I remember correctly, which is damn near 50% upside from current levels. Well, depending on what it's doing right now today, but. You have a lot of money flowing into this space. It just makes sense from a standpoint and hell their name is on that, a beautiful new, however, billion dollars. It took to build that a football stadium out in California.Yeah. That, that, that, that was definitely an expensive sponsorship. I guarantee that. Yeah, I see, I see I'm using my trusty Benzinga pro here, looking at the recent analyst price targets. Uh, you know, I see the Jeffries yesterday that you mentioned at 25 Mizuho out there at 20. And then the, the low of the street credit Suisse came out about two weeks ago at 16 and a half.Um, and, and, and so, so BA basically, uh, is, is the thesis on this one? Daniel it's it's right. Space, right stock within that space. Yeah, absolutely. It's just, it's more of a momentum play. Uh, I liked the idea in general, but it's just when you have massive amounts of money flowing into that and strong brand types, uh, those are great for trading opportunities and then they can turn into long-term holdings.Okay. Yeah. And I'm zooming into a five day chart right now. So it's what we're looking at. I believe our five minute candles, let me get a, from a 10 minute candles, five day chart. Um, and, and we, we definitely see that rip higher with the market yesterday, uh, in, in tack down another 2% so far today. So, so, and let me throw this one out here, but I definitely see this symbol come up if anybody has long.So if I take her S O F I give me the one in the chat, if not give me the two, I want to get a sense of where the crowd is at on the. Uh, I I'm not in so far, but I do own a couple of the online brokerages. Um, one that I'm getting hammered in right now, uh, I've trimmed the position, but still have a little bit of a position in his tiger.Ticker T I G R a. It's like, like the Robin hood of China, Singapore, et cetera. Um, wow. We have a lot of Sophie owners in the chat check this out. Okay. So a lot of people who like sofa, I can get behind that. All right. Okay. All right. Daniel, anything else for us before we gotta hop? Uh, yeah, if you want to have a fun, uh, political pick a Smith and Wesson brands, uh, they're a pure play on fire symbol on that one.S WPI. Thank you. You can see, we impressed. So that was the first you're you're on stock number four, and I knew the first three. Okay. There you go. All right. SWB. So that massive spike there was after an earnings release, uh, they've recently, uh, I think right around the first of this month, September, they did their quarterly earnings, but that massive spike there, that what you can see on the chart is they blew out the numbers on the earnings release.And then it looks like the Reddit crowd got involved because look at that massive sky high, I mean, that thing just went parabolic for several trading days. Uh, this is a pure play on firearm. I know that's a touchy subject politically, but when you look at the numbers, the FBI background checks and things are falling year over year because of the strong, strong comps that they're compared to during the riots and the 2020 and all that kind of thing.But 50% of new gun buyers are women. Um, everybody I'm a small town guy. I grew up around firearms. So I'm biased as everybody else is, but I'm biased towards them. This is a company with no debt. They are. In a position to continue raising their dividend. Uh, it's not impressive. It's not a high yielding thing, but they are buying back stock as well.And you have a solid company with an amazing brand name and you have a product that people are, um, you know, it's, they have a huge demand for their products right now, their backlogs or their inventories about an eight weeks, which is kind of where they want to management. They're going to have issues along with everybody else with supply chains.When you get a great business in a fantastic financial shape and a well-known brand, um, that's, that's a good one right there. So, and it's got a decent short interest. So that, that spike that you see on the chart that could easily happen again. Alright. I like it. It's interesting. I have, uh, let me throw this edgy Daniel, then we're going to have to hop in a minute here, but here here's my take on the gun stocks is I feel like literally always, or at least.Once a year for the last 10 years, there's like a shortage. And like, there just becomes this narrative, all of a sudden that there's a shortage on guns or there's a shortage on ammunition. And then just a ton of energy pops into these stocks. And you know what I mean? It's it, it just seems like, uh, like, I don't know, like I'm sick, I'm bored of the narrative.Yeah, it does. I mean, and you're right. That does happen. I will tell you the biggest risk I see. This is, and why I think you have some short interest is you have such a political movement and like your major funds and investment companies like BlackRock and those, they have, they kind of shun these kinds of stocks.So you have a great business. You have high profit margins, but what's going to be. The big guys from flowing more money into these stocks is political reasons. That's your biggest risk in my opinion, but yeah, you're right. They, they get hot. They could be used as tradable securities. So that would work out for your listeners, but I wouldn't feel bad about buying and holding this either, but yeah, if you want to trade the pops and, uh, you know, sell on the rips and buy on the dips, that's a great idea.Right? Alrighty, Danielle, I appreciate you hopping on with us. How can folks stay in touch? Where should they go? What should they check out? Yeah. Uh, my email isDaniel@curzioresearch.com. Be sure to check out Curzio research.com and our wall street unplugged podcast that we now do over Tuesday, Wednesdays and Thursdays every single week.Alrighty. There it is. Thank you for joining us, sir, and dropping the ideas. All right. All right, guys. How was that? I see recurring theme of the chat and talk about Viacom. We will get the via, comes to your V I a C, but, but without further ado, w w we're we're going to keep the show rolling. Uh, we, we've got a nice slate of guests coming in for us today.Uh, first up CEO said, taro, biopharma, Mike Handley. I'm going to go ahead and let's bring Mike onto the. How are you doing today, sir? Thanks for that. Absolutely. Uh, and, and everyone, the stock symbol is ticker. S T a B said Sandy tango alpha Bravo, Bravo. Um, long week. Um, but, but, but my, my, I I'm one for, for a good stock symbol.You know, if, if, if a, if a company has a good ticker symbol that like automatically notches it up in my book, so maybe we could just start there for a second. Uh, why. Yeah. Interesting question though. Thanks for having me again. Yeah. Stab is a Sitara biopharma, obviously ticker symbols are a little hit and miss.Um, we were going for sta T but uh, stab is memorable. Um, and it also goes with our tagline, take a stab at stopping. Right. So, okay. We think it's more memorable than most taglines. Absolutely. No, that's great. I love it. It's like some of the ETF funds, right. I read out to them to I'm like, I don't know how you guys pick the ticker symbols, but if there's like a group or like, you know, something you survey include me in there, I haven't gotten any responses, but I love the memorable ticker symbol for sure.Absolutely. And, and, and Mike T taking a step back from the ticker symbol to the company. Uh, could you just give us a little bit of an overview on Satara for anybody out there who might not know. Yes, the terrorist, a, a company that just became public, uh, July 27th through a combination merger with Cleveland Biolabs, which was a NASDAQ listed company.I've been running a state Tara since April of last year. Um, we, uh, talked to Cleveland Biolabs synergistic platforms. So we're most looking at immunotherapies and, uh, it looked like a good combination of two companies. So we combined the two companies officially July 26. Or July 27th. Yeah. And I've been trading since then, and I've been working with circuits and getting visibility for our pipeline and we're about ready to initiate some Wade stage drug programs, uh, that we're really excited about that should help patients and deliver some new immunotherapies to the field.Excellent. And Mike, you, you, you, you mentioned, I think it was April, 2020, that, that, that, that you joined the company, is that accurate or that you've been running it. Yeah, I've been running it since April, 2020. We've done two acquisitions, um, raised or secured over a hundred million dollars in gone public.So it's been a busy what? 17 months. Yeah, no kidding. So, so, so, uh, the, the next question I have is, uh, is on background and, and I, I sort of have two pieces of it. Um, and, and you can pick the answer one, one, or both, uh, but, but either what, what was the impetus for the company? Or can you talk a little bit about your career prior, prior to.Yeah. Yeah, I'll answer both. So I've been in front of biotech for 24 years of running companies for the last 15 years. I'm very interested in the biotech space. Immunotherapy space started off at Amgen Genentech, which are the two big giants and biotech, of course, Genentech bought by Roche now, but Amgen still, uh, independent, uh, took over 17 products to market.You know, raise close to half a billion dollars and, uh, Brandon's is the terror. Like I said, April last year, they had a very interesting portfolio and uh, thought, um, this would be a great public company, a great opportunity to get some drugs, to some much needed patients, um, that don't have any other alternatives that are.Uh, so very excited about our platform, multiple shots on goal. We've got a great story and it resonates well with the street, from our interactions and our non-deal roadshow we've been doing. So we're very excited, better than current position. Okay. And I'll, I'll pick up on that roadshow comment that you made, you know, and w when you're going out to wall street and you're talking about the company, uh, you know, what, what aspect of the business is, is getting investors most.Yeah. Great question. So if you follow the biotech sector, we've seen immunotherapies just exploded in the past five years, I'll use two examples, Humira, which is a TNFL Footlocker sells about $19 billion a year. What's number one, uh, drug selling in us. And I think the world, and then you look at Keytruda.Merck's drug is a PD, one PDL, one inhibitor. It sells at 13 billion. It's also. Um, our approach to immunotherapies is a little bit different than what big pharma is doing. Those particular drugs suppress the immune system, uh, as in Humira. And they do that, um, to account for, um, uh, Crohn's disease, IVG rheumatory arthritis, and then the cancer drugs take the brakes off your immune system.So in effect, our narrative to wall street is the current immune therapies out there or. And they're generating a lot of cashflow and they're helping patients, but they also come with a large amount of side effects because you're suppressing the immune system. Um, in the one case with the Humira and other TNF, alpha blockers and the other cancer cases, you're increasing the probability of hyper inflammation in those patients.And that's been a cause and a concern and a warning for Keytruda, both great drugs, uh, both help patients, but we think there's a better way of doing immunotherapies. And that's what we're telling the street. And they're gravitating. Okay. And can you talk to us a little bit about him? Question in specifically the integration stuff.Yeah, I'm close was the second company we acquired. Um, they're a research driven company with, uh, cashflows and, uh, we're in the process right now of integrating them into our R and D platform. And they're working on our second gen, uh, immunotherapies. And we've got a couple of, uh, potential interesting candidates we're working through, but the inquest simply adds to.And, uh, we're building, I think one of the more interesting and the largest tool, like reception pipelines, um, in the U S if not the world, and that provides us with, again, a lot of shots on goal and a lot of ways to help patients. Okay. And I guess maybe taking a, a step back or a step higher than, than, than inquest specifically.Uh, but, but how do you see M and a fitting into the company's roadmap and why have you made the choice that, Hey, that that's the route that we're going to pursue to really grow. Yeah, I'm a firm believer the, uh, Biven bill, right. It's a lot of companies out there that have interesting technologies or platforms that would take me, you know, months to years to replicate the same thing and a much higher dilution to our shareholders.So, um, being opportunistic, looking at companies with the us. Uh, or complimentary or technologies that are complimentary. Um, we'll definitely use our public stock as currency. And like I said, we're well capitalized and we'll be opportunistic about what we go out and acquire, but it's definitely in the mold of our strategy going forward.So look at M and a, and be opportunistic about increasing our pipeline, both depths. Okay. And Mike, let, let, let me ask you one more question. And this one is always a tough one. Uh, but, but if you had to name one, one thing that you're most excited about, so somewhere on the roadmap, what, what would that one idea.Yeah, great question. Everybody asks me, um, obviously cancer therapies are near and dear to everybody's heart. Everybody knows a relative or friend that has cancer, and we've got some very good cancer therapies for developing an adjunctive treatment. Um, but probably the drug program I'm most excited about is our Crohn's programs.So what we've seen in phase two data is, uh, double the rate of remission in patients who take a once a day world. So current standard of character, marrow, injectable, biologic, um, you get a remission rate of in the low thirties. Um, our what our data, what we've seen is about a 67% remission rate, four weeks, once a day dosing, that is very compelling.And then the other thing I'm really excited about Crohn's is currently for pediatric Crohn's patients. There's nothing out there that, uh, Works. Well, all of that is black box warning. And as kids develop their immune system, it's really hard for them to be on these biologics, like Humira, Stelara, and Remicade.So we're running a phase three pediatric study that should kick off by the end of the year, um, in, uh, pediatric Crohn's patients. And we believe this will be a viable alternative to all the kids out there suffering from Crohn's disease. Awesome. Mike, I appreciate you taking the time to come on with us today.CEO said Tara, a ticker S T a B. And as I said, I do love that symbol and I love the memorability of it. If that's even a word, digging a stab at cancer. Awesome. Yeah. Appreciate it. Thanks for, thanks for your time. Have a good day. Absolutely. You as well. All right. All right, producer, Amy, what do you think.Love it love the company. Love the ticker. Great to have Mike on. Um, but Luke, we have an absolutely packed power hour show. Today. We brought on Daniel from wall street and unplug. We brought on my from Sitara buyout. Now it is time to bring on Sean C Sean folks and CEO of night food. Um, so without further ado, oh wait, wait, wait.Celsius is a hundred bucks. No way. Wait, did we ever get the video of Jonah shock? He said, he said he was going to shut you down. He did it leap and you're sleeping on Celsius. Sorry. Um, yeah. And then you also saw the news that Jonah said a Celsius is sending us some, some drinks to Florida for the conference.Yeah. Guys, if you want to come hang out with me and producer a B in journal up them and put the link in the chat, come say, hi, it's going to be about. That's really the only thing that's keeping me going at this point. So there you go. It will be a good time. Um, all right, Luke. Well, without further ado, I'm going to go ahead and bring Sean folks in on the show.Sean CEO of night food. Thank you for joining us on the Benzinga power hour. How are you doing on this beautiful Thursday? Great. My pleasure. Happy to be here. Great to have you, um, before we get started, do you mind just giving some, uh, background on the company for maybe some of our audience that may not be familiar?Sure. So across the country, On any given night, you've got over a hundred million people that are snacking in between dinner and bed. Uh, the most popular choices tend to be things that are loaded with excess fat, excess sugar, excess calories. Cause that's what we're hard wired to create. So you've got all these snacks being consumed, and they're not only unhealthy, but they're actually disruptive to sleep.When you eat the wrong things before bed, it can impair your sleep quality. So knowing that so many people are snacking at night on a regular basis, what night food does is we deliver healthier snack options that are specifically formulated to satisfy those nighttime cravings, but do it in a better, healthier, and more sleep friendly.There's plenty of companies out there over the last 10 or 15 years that have launched and had a lot of success with better for you snacks, which are generally healthier in terms of, you know, protein content or sugar content or caloric content, but only night food has looked at. Knowing that people are snacking within that hour or two before bed, what should we be putting in our bodies and what shouldn't we be putting in our bodies to make sure that we get the best night of sleep and sleep is becoming more and more of a challenge for a lot of people, uh, especially now with COVID.So we think the timing is great, and we think there's a billion dollar category to be had here in the category of nighttime. So is this something, I guess that took a lot of, you know, scientific research on, on night foods and to figure out like what it is specifically about, um, you know, what's in typical ice cream that can disrupt someone's.Well, I mean, there's been a general consensus for quite some time, and there's been a lot of research over the years. Uh, you know, excess sugar, uh, fat and calories are problematic. Um, you know, there are certain nutrients that can be beneficial, magnesium, calcium, zinc, vitamin B6. Uh, so the research really existed.Uh, and when we launched our, our challenge was. You know, to formulate a great tasting product, uh, with all these ingredients that can satisfy those cravings in that way. So, uh, really we stood on the shoulders of the existing research, which was out there. And it's really interesting because with so much snacking already happening at night.See, this is, this is not a behavior. That's, uh, it's not a trend. It's not a fad. This is how humans are wired. We're wired to crave these things at night, so it's not going away. So there was a lot of talk and a lot of research before we launched, but nobody had ever launched a product into the category, which we thought was really interesting.Now we've got Nestle, we've got Unilever, we've got Pepsi. They're all talking publicly about this category. Um, but, but we're the only ones operating in it. And so the challenge for us was not really to figure out what our snacks should be. An ice cream is the first, you know, what they should contain. It's more about really educating the.Got it. Yeah. And I mean, it sounds like, I don't know if it's fair to say, but you're kind of, um, you know, hacking the human, like hardwiring of wanting to crave these things, but then we, you can eat these things, but in it, and it tastes like what we're craving, but it doesn't have those kinds of detrimental effects on sleep.Is that. Yeah, that's exactly right. I mean, you know, th the reason we crave these types of things at night is because putting extra fuel inside your tank before fasting is a survival mechanism that really served well, you know, the caveman ancestors, uh, you know, if, if they didn't have the resources, if they didn't store excess fuel inside their body, in the form of calories, they were less likely to survive.And specifically before the nighttime fast, that's when those cravings, that's why appetite peaks. Um, so yeah, what we're trying to do is, um, make sure that, that when you do give into those cravings and most people do that, you're doing it in a way that's beneficial and not detrimental. Got it. Um, so real quick on the business side, um, I understand.Uh, you know, you guys do a lot of I'm on the website right now, a lot of direct to consumer. Um, I see, you know, shipping is only 6 95 for an eight, eight pint order, but what about all on the B2B side, on the business to business side? Uh, you know, where does night food stand as far as with partnerships with, uh, you know, places like hotels and chains like that?Yes. So, so from a retail distribution perspective, we're in divisions of Albertsons we're in, uh, almost a thousand Walmart stores across the country. And other supermarkets and we're expecting to add quite a few more supermarket chains, uh, in the spring. You know, those meetings that are going on right now and things are being finalized, but the real cab.And what's going to be happening in the next few weeks and months is the hotel launch. So we were making a big push into hotels prior to COVID and then obviously COVID slowed things down quite a bit, but, uh, in the hotel environment, you know, everybody's been in the supermarket and you see there's there's six or eight doors of ice cream.There could literally be hundreds and hundreds of different varieties, different skews in there in the hotel environment, you've got a consumer that's typically purchasing for more immediate consumption. Our packaging, as you can see there says sleep friendly right on the front. We sell very well in the hotel environment in the past, we've sold pint for pint with Ben and Jerry's pint for pint with hogs.And we got contacted, uh, late last year. One of the leading global hotel brands just conducted and completed a test of night food in several of their hotels. And the test went very well. And what that's going to lead to is a national rollout of the ice. And what we believe also could be the ability to very quickly introduce additional product formats into that hotel environment.So the product sells very well. There, it's a great opportunity to capture high margin businesses, much more profitable than the supermarkets, but it's also really supportive. Of the supermarket distribution. Uh, we've seen, um, we've seen RX bar get into gyms and use that gym distribution to support their supermarket rollout.And then they sold to Kellogg's for $600 million a couple of years ago, Oatley also, which just IPO a few months ago, they very publicly stated their strategy is to roll into coffee shops. They've got to deal with Starbucks. Consumers will interface with the brand in that environment. And that will build trust that build awareness, and then the consumers run into the supermarket and start buying the product.So we think the hotel piece, obviously it's going to be great revenue contribution, great profit contribution, uh, but also really, really supportive of our supermarket expects. Yeah, that that's good insight there as to how you can kind of raise brand awareness through some of these, uh, B2B deals and that way, um, you know, bolstered the, the B2C sales as well.Um, so, so you mentioned some other of the big ice cream players out there. Um, do you see Knight food as a potential, like takeover target down the line? Uh, I do. I think it's, I think it's going to be inevitable. I think we're going to force their hands. You know, uh, when you think about it, Nestle and Unilever are the two largest out there, and they've both publicly expressed interest in this category.And, you know, especially being in the hotel vertical, it's really going to cement us as, as the category king and the category leader, you know, we've seen five-hour energy still sells over well, over 80% of the energy shots in the country. You know, every, everybody in the energy drink business just about has launched a shot and five-hour.Just swats them away. And I think, you know, if we play our cards, right, the same thing will happen in the nighttime nutrition space. And specifically being in the hotels makes it really hard for somebody to come in and try to outflank us. It's a lot easier to do if you're relying strictly on supermarket distribution, there's a lot more opportunity for the big players to come in and try to push us around.But in that hotel space, I think it's really going to insulate us quite a bit. Um, it's also going to really accelerate. Um, our growth curves so that by the time anybody decides they want to get in, we're going to be running out with really tremendous revenue growth as we scale into the hotels. And, you know, even if the first company decides they're going to try to launch against.Then what is the second company going to do? Are they going to play for third place? Are they going to try to require, uh, the category pioneer? So, um, I do think it's inevitable. Uh, you know, we've got some revenue targets that, you know, when we hit those, everybody's going to have to decide how are they going to.One thing. I didn't mention almost half of all snacking takes place at night. This is not a small niche. This is not five or 10%. This is almost half of all snacking. And it's not just Unilever and Nestle. Everybody knows about this Mon delays and Kellogg's, and Hershey's any company that's in the snack space.They know when the Oreos and the Doritos and the Ben and Jerry's are being eaten. And once we show that consumers are wanting and willing to make a small change in order to support better quality. Right, which is an easy jump for any consumer to make. Once these big companies realize that, then they know that the whole landscape of the snack category is going to change.You're talking about almost half of all snacking up for grabs. When all these cookies, chips, candy and ice cream are being consumed between dinner and bed. I don't think they're going to be able to lay off. I think we're going to be fielding. I mean, we've already been contacted by some of the companies, um, at least one of them that I mentioned on this call or.Um, I think the phone's going to start ringing once we start to really scale our revenues coming up. Got it. Yeah. That's exciting. I guess a, you know, a follow up question on that would be, how would you, uh, you know, quote unquote, you know, force their hands, as you said, you know, like what's to stop, you know, Unilever or, you know, uh, Ben and Jerry's whoever it is from going out and trying to develop their own sleep friendly.They could certainly do that. It's really not the way things are done. I mean, there was nothing stopping Kellogg's from making their own, you know, cleaner labeled bar. Uh, there was nothing stopping Hormel, which already owned Skippy, peanut butter for making their own organic brand. But no, they acquired Justin's.Um, and, and up and down the line, you know, uh, it's just not the way things are done these days for them to try to launch against us when they see a category pioneering. Growing at, at, you know, an exponential growth in a category where there's obviously going to be one king and lead player acquisition is the only way to go.Um, everybody else is going to be competing for second place and they all know that. Got it. Um, all right, Sean. Well, thank you so much for joining us on the power hour. Uh, but my final question thought would be, have you ever thought about doing a 180 and maybe making a caffeinated ice cream for breakfast?No, no, I've never heard about people have said we should make day food as well as night food. But you know, you look at the NyQuil analogy, right? And yes, they, they do make DayQuil now, but, but by, by, by commanding a specific day part, Luna bars, another great example when cliff made Luna bar as a protein bar for women, people said, Hey, you know, you're, you're eliminating a portion of your audience and the same thing with Nike.Uh, back in the mid to late sixties when they launched, but there's a lot of power in that kind of focus. And by being the company about nighttime snacking, when I was half of all snacking takes. At night, there there's power in there. We don't feel that it's limiting at all. We feel that it's laser-focused and it's not only going to be, uh, be more powerful in terms of our ability to grow, but it's going to present a more powerful, uh, value proposition to, uh, investors, whether that's our, our day-to-day shareholders or ultimately other conglomerates that might choose to enter the space through acquisition.Got it. Well, Shawn, thank you again for coming on the show today. I look forward to having you on again, anytime night, food has some exciting updates or news. We'd love to have you back on to kind of, uh, you know, bring that news to her. Fantastic. Thanks for having us. I know you mentioned Celsius hitting a hundred, you know, I've been studying Celsius.Um, you know, the, the chart is amazing and you see, there was years, you know, they were cranking away and the stock didn't move and now they're really getting rewarded in the marketplace. So congratulations to John and the whole Celsius team as well. Yeah, of course. You, you, you mentioned the chart, you a trade stocks.I don't, but I, I do feel a lot of questions from investors and certainly, you know, I'm studying Celsius to see, okay, you know, what, what was going on during those years? Where were, were, wasn't moving, you know, what changed? And, and it's a really, uh, really amazing thing to look at, but now I only do it because, because I'm asked.A hundred percent of my net worth is in night food. And, uh, my, my wife and I are okay with that and my kids. And we're very excited about. There you go. Who knew, who needs diversification. All right, Sean. Thank you for joining us. We'll be in touch. We'll be in touch. We'll we'll have you on again soon.Thanks so much guys. A B I was, I was late for that. Um, but. Aye. Aye. Aye. What I want to say. It was also in the chat, which was, uh, someone who, who said this in the chat. They have very cool labeling. I feel like a, uh cause I, everyone always like, whenever you take like a marketing course, they always say, oh, labeling and packaging is so important.And I think, oh, that doesn't work on me. And then here I am. I'm like, oh yeah, they have, they have cool label. I might try that because all that stuff, if that works is done on the subconscious level. So you're not actually. Um, you know, consciously saying, oh, I'm going to buy this because it's got better packaging, but you subconsciously do, did you not?I may have missed it. So I apologize. Did you ask for, for free sample? No, I forgot to do that. I don't know if Sean can still hear us, but if you can, you can email email, I'll send you our address and we will gladly take some free samples. Um, yeah. Spencer, the only question you caught was mine about the, the morning ice cream.Hey, if they're not going to do it, that might be a whole, whole new market out there. Can they, can they, I don't know if you can ship by stream in the mail, whatever, whatever, and you missed it on the, on the website eight by eight pints. It's only $6 and 95 cents. It's a great, I was preparing, I was preparing for our health care conference negative next week.So I apologize for, but I'm here now. I'm here for our next, our next guest, which I'm excited for AB. Um, we have Todd Lachman, who is the Sovos CEO. It's very exciting. The company is IPO in today. Um, and, and we are getting fresh new public companies on the Benzinga power hour. Nowhere else. Can you go on YouTube to find content like this?So smash the like and subscribe. If you haven't already Spencer, without further ado, let's bring Todd on this. There is that guys doing great to be with you today? Yeah, Todd, I'm sure you're very busy today with Sovos IPO in. Um, are you joining us live for I'm from New York? I am joining Vive from New York.Uh, the NASDAQ tower right here. Wow. How's the day going so far busy, but great. Uh, honestly guys it's, uh, I mean, what an exciting. You know, for, uh, for so most brands we're thrilled. Uh, know, we're just thrilled for the journey ahead. It's like to tell you more about it today. And so maybe let's just start with what, what, what the company is, and then I'll, I'll get to my, my, my real questions.So look here. Well, I've been in the industry for awhile, so throughout my career, Plus year time. And in CPG, I was, you know, across brands, categories, companies, geographies. I was always struck by the fact, you know, that you've got these smaller on-trend brands growing at the expense of the largest brands in the store.Some people call them challenger brands, disruptor brands at Sovos. We call them one of a kind brands, but I, I felt that there was an opportunity to create a company specifically suited in order to. Uh, have the talent, the culture, the capabilities, the infrastructure, to build a portfolio of these, one of a kind brands.I mean, w we look specifically for brands that have tastes superiority strong, consumer affinity, high quality ingredients with a cleaner label and authenticity at their core. And that's what we have with Rayos Michelangelo's Noosa, Birch benders, fastest growing food company in the U S uh, outperforming our categories by 25 percentage points.And the journey is just. Okay. Since we were just talking about it, uh, and I didn't get to ask our last guest, I'll ask you Todd, just about packaging and labeling and branding and, and just how important on a scale, like one to 10, how important is that for you? On a scale of one to 10? I don't know if it's, uh, it's, it's really important.Um, I don't know. Let's say it's like, let's, let's say it's a, you know, a seven, eight, you know, kind of what you're talking about, but what's, what's interesting. I think it's more important, uh, for brands like ours that are premium priced high quality. The difference is so different. What's in the jar that, you know, that is the most differentiating aspect for us.The package is. But what's doubly critical. Let's take a brand like Rayez. You've got whole Italian peel tomatoes, fresh basil, fresh onions, olive oil inside that jar, slow simmered and cooked and open kettles. And you've got the market leaders with paste and added sugar and added water and canola oil. So just to kind of highlight the difference in our products versus.The difference of, uh, you know, once they're, so with us, the reason we're able to command a premium price. I mean, Rayos is three times the price of the market leader Rayos is growing at 42%. We're almost the number two brand in the category and the market leaders are flat to declining. So what's in that package is really the magic that's delighting consumers.So, is it mostly, you know, brands under the Sovos umbrella? Are they mostly, um, you know, healthier alternatives organics, um, or is that just happens to be the case with a rail? Sure. No, all our brands, we look for brands with high quality ingredients and cleaner label. Let's say Birch benders has an organic offering, a high quality ingredients.Uh, basically almond flowers, tiger, nuts, uh, you know, all sorts of high-quality ingredients in those products. We have organic, we have a keto and paleo offering keto and paleo Birch benders, pancake waffle mix, two of the fastest spinning items. Then you've got a brand like new stuff, whole milk, real fruit, north American wildflower, honey, with a proprietary process.I mean, this is a great example of guys that, you know, we're, the category is going one way. How much taste can we take out of the container? We're looking at, see how much tastes we can put into the product. And that's why consumers are flocking to new Senate's it's growing well. Well, ahead of the category, very differentiated.Oh, go ahead, Spencer, go ahead. Have you, or maybe down the line, have you guys ever sold like individual brands to maybe market. We, we have acquired we've averaged about four acquisitions a year. We have not invested in asset. We have no plans to we're building a portfolio of one of a kind brands. And quite honestly, we have, uh, you know, plans to acquire more brands in the future.Uh, Y you mentioned the term CPG consumer packaged goods. Why would a consumer package goods company IPO right now? Why. Sure. Well, I, you know, I think just speaking for Sovos brands, we're of the size, you know, the scale, the profitability level, then it's appropriate for us. We've been, uh, you know, we were founded four and a half years ago.We're a $669 million of sales growing at 31% were profitable. This is not a story where I'm saying, Hey guys, I'll be back on in five years when I am profitable. We've been profitable from a, from day one. Uh, you know, so I think at this level, and then look at it, it provides us with, uh, with the balance sheet and the infrastructure and, you know, the sort of widen the aperture to whether it's talent, acquisition, future M and a it's just, it's the perfect time, honestly, for, uh, for Sovos to become a public.Got to ask you about the Al green in the room, which is just, um, uh, the impact that, that COVID the pandemic has had and on everything, right? Uh, whether it's supply chains, whether it's labor costs, uh, whatever. However, you want to answer this question and take it, but like what, what is the impact that the last year and a half has had on your business?Sure. So. Look, I mean, I think there's a few things that, uh, if you just think from a brand perspective, we have brands that have that taste superior brands that have strong consumer affinity with the type of ingredients that we have. They have a higher propensity to stick in a household after trial. Then highly substitutable me to mainstream brands.So we have gained the amount of trial that we've gained over the past 18 months has been prolific just during this, this horrible pandemic. And if you look at a brand like ratios, our penetration is double from 5% to 9.6%. That's why the brand is growing at 42% last 52 weeks versus, you know, the. You know, flat.So, uh, you know, what we've seen is we're gaining trial of our, you know, of our premium brands and they're sticking in the, in the household clearly from a supply chain standpoint, uh, you know, just like everybody, we've had to be really nimble and tenacious and keeping our products and supply. And I'll, I'll tell you one thing we're in a year, as difficult as it was in 2018.And a company of our size. We've got vendor of the year at target and supplier of the year at whole foods. Wow. Because you know, one of our core guiding principles is obsessed with the front line. You know, we're the more time we can be focusing on our retails or on the consumers, on our frontline heroes that come to work every day to make our delicious products.Uh, I mean, that was a real, a Testament to the fact that, you know, our, our phenomenal employees are working so hard to keep our customers in. So Todd, I don't know if you have kids, but it's oftentimes hard to, uh, to pick a favorite kid, but I'm going to ask you, I'm going to ask you to do it here out of the four brands, uh, currently right now under Sovos, which one is your favorite?Or maybe what's the most popular in your own household? Yeah, I do have three kids and we always joke about which job I'm not going to ask you that question. I'll ask you, Kyle Paul and Isabel are listening today. So I will, I won't treat. But, uh, I apologize. I'm going to tell you right now that I've got four outstanding children.So those portfolio with those, with Noosa, with Birch benders, uh, it, look, you got a brand like radios. That's changing the sauce category forever in regards to whole tomato sauce, you have nuisance. Is there a category in and of itself, it tastes, tastes like yogurt. And then we couldn't be more excited that we just added Birch benders to the, uh, to the portfolio, the fastest growing frozen waffle they're a brand.We just launched it into the baking mix aisle with some Quito offerings. So, uh, for four great children in the, uh, in the Soho's portfolio. Oh, favorites. Todd, is there a product category you're not in, but you very much want to be in right now. So great. So I'd say number one, we were at about seven categories.Now. We really like the categories that we're in today. I would say I'm not going to choose a category, but I would say that there are categories adjacent to ours or close to adjacent to ours, that we also really like, we, there are other sleepy categories that are in need of disruption or are being disrupted today by other brands that we would love at some time to add to the Sovos portfolio.So, you know, Some companies are sort of attracted to the category. that? Wow, this is like the place I've got to be. I'm not going to name that area, but there's, some of those were, you know, we're sort of looking at a different direction or those categories that, that, that are right for disruption. I'll tell you a category that we entered with ratios with soup.Everything is in a can. Why can't it? The consumer gets sued. That's not an, a camp. Well, until Rayos came in with glass jar. Absolutely delicious meal and a jar consumers. Couldn't get Superdome in a jar and now they can see that great delicious soup. And it's the, now the number five soup brand and only 18 months.Uh, last one for me, you mentioned you're in a target you're in whole foods. I assume you're nationwide. If you're in both of those locations, have you considered direct to consumer model? Sure. So we, uh, we're partnering well, their customers, whether it's clicker collect and on their retailer e-commerce programs, we do sell an example of what we do sell direct today.If you go on rails.com, we have great gifting baskets. We have some super premium rails, limited reserve products. So aged balsamic, white truffle marinara. We do sell a direct some, uh, some super premium, super, super premium products on the, uh, on the, on the radio site today, as well as, as well as Birch benders.So, um, we do have some experience and, uh, in that area, but not for the, the, the main, the main products, the main products are on only in stores. Uh, the majority. Yes. Okay, cool. All right. I, I think we covered it. It's one o'clock we don't wanna take up too much of your time. It's been a busy day. We've we we've been on with Todd Lockman, the CEO of Sovos brands, ticker, S O V L IPO, like for an hour ago, actually.Um, so, uh, yeah, Todd, thanks so much for, uh, taking time out of your day to, to hop on that. And you can get to ring the bell today. Yeah, we do. We do. Awesome. All right. We'll be watching. We'll be watching. Hey, great to meet you both. You as well? Uh, that was fun, Spencer. Um, I'm hungry, man. As I know, we went straight from ice cream to more delicious food.It's like, what are we, what are we doing right at lunchtime to, oh my gosh. Yes. I'm Hong it's one. O'clock let's go eat everyone. Uh, grab some food and come back to, uh, get technical with you're starting live right now. AB I think, uh, can we get, uh, I think we'll get Neil going and if you haven't already guys drop us.How many likes are we at? Let's find out not enough, not enough. And I'll tell you that much or at wait a minute. Wait a minute. Wait a minute. We're at 52 50. Oh guys. Come on. Four interviews today, three public company execs, one IPO and a Partridge in a pear tree. We did it all for you today. So at least get us to a hundred and.Th th that, that that'll be, that'll be that I spent, I'm going to hop out and get Neil started. I will see you when I see ya. Okay. AB was see over on gay telling all this stream will end. It'll redirect you automatically to get technical. That's how we do things here on Vincent. Any feedback, questions, comments, concerns shows admin zynga.com.Email us, check out Benzinga events.com. To see all of our future events from our, our healthcare conference next week to cannabis next month to, uh, everything. All right. That's a wrap for me here. Hit the, like us here, you guys over on getting technical with, uh, wacky Neil Hamilton. 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